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  • Markus Schlaich
2016

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Renal artery anatomy affects the blood pressure response to renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Duval, J., Lee, R., Sata, Y., Krum, H., Lambert, E., Peter, K., Head, G., Lambert, G., Esler, M. D. & Schlaich, M., 1 Jan 2016, In : International Journal of Cardiology. 202, p. 388-393 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Renal denervation for resistant hypertension: Closing in on potential confounders

Schlaich, M. P., Schultz, C. & Shetty, S., 2016, In : Journal of Hypertension. 34, 8, p. 1505-1506 2 p.

Research output: Contribution to journalLetter

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 othersVonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney

Singh, R. R., Easton, L. K., Booth, L. C., Schlaich, M. P., Head, G. A., Moritz, K. M. & Denton, K. M., 26 May 2016, In : Scientific Reports. 6, 26777.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Residual sympathetic responsiveness after catheter-based renal denervation: Lessons from renal nerve stimulation

Schlaich, M. P., Sata, Y. & Hering, D., 2016, In : Hypertension. 67, 6, p. 1117-1118 2 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning

Lambert, E. A., Thomas, C. J., Hemmes, R., Eikelis, N., Pathak, A., Schlaich, M. & Lambert, G. W., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 2, p. H364-H370

Research output: Contribution to journalArticle

24 Citations (Scopus)
7 Citations (Scopus)

Three-year changes of prothrombotic factors in a cohort of South Africans with a high clinical suspicion of obstructive sleep apnea

Von Känel, R., Malan, N. T., Hamer, M., Lambert, G. W., Schlaich, M., Reimann, M. & Malan, L., 2016, In : Thrombosis and Haemostasis. 115, 1, p. 63-72

Research output: Contribution to journalArticle

5 Citations (Scopus)
Open Access
File
5 Citations (Scopus)
194 Downloads (Pure)
2015

Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Lambert, E. A., Sari, C. I., Eikelis, N., Nestel, P. J., Phillips, S. E., Hering, D., Karapanagiotidis, S., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Apr 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 4, p. 1544-1550 7 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Central arteriovenous anastomosis in resistant hypertension?

Schlaich, M. & Hering, D., 2015, In : The Lancet. 385, 9978, p. 1596-1597 2 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)

Device-based approaches for renal nerve ablation for hypertension and beyond

Thorp, A. A. & Schlaich, M., 8 Jul 2015, In : Frontiers in Physiology. 6, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Effects of renal sympathetic denervation on urinary sodium excretion in patients with resistant hypertension

Pöss, J., Ewen, S., Schmieder, R. E., Muhler, S., Vonend, O., Ott, C., Linz, D., Geisel, J., Rump, L. C., Schlaich, M., Böhm, M. & Mahfoud, F., 29 Aug 2015, In : Clinical Research in Cardiology. 104, 8, p. 672-678 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

First report of the global SYMPLICITY registry on the effect of renal artery denervation in patients with uncontrolled hypertension

Böhm, M., Mahfoud, F., Ukena, C., Hoppe, U. C., Narkiewicz, K., Negoita, M., Ruilope, L., Schlaich, M., Schmieder, R. E., Whitbourn, R., Williams, B., Zeymer, U., Zirlik, A. & Mancia, G., 2015, In : Hypertension. 65, 4, p. 766-774

Research output: Contribution to journalArticle

116 Citations (Scopus)

Health-related quality of life and blood pressure 12months after renal denervation

Lambert, G. W., Hering, D., Marusic, P., Thorp, A., Sata, Y., Lee, R., Duval, J., Hammond, L., Head, G. A., Esler, M. D., Lambert, E. A., Dixon, J. B., Dhar, A. K., Barton, D. A. & Schlaich, M., Nov 2015, In : Journal of Hypertension. 33, 11, p. 2350-2358 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Home blood pressuremonitoring: Australian Expert Consensus Statement

Sharman, J. E., Howes, F. S., Head, G. A., Mcgrath, B. P., Stowasser, M., Schlaich, M., Glasziou, P. & Nelson, M. R., 2015, In : Journal of Hypertension. 33, 9, p. 1721-1728

Research output: Contribution to journalArticle

32 Citations (Scopus)

Metabolic syndrome: A sympathetic disease?

Schlaich, M., Straznicky, N., Lambert, E. & Lambert, G., 1 Feb 2015, In : The Lancet Diabetes and Endocrinology. 3, 2, p. 148-157 10 p.

Research output: Contribution to journalComment/debate

47 Citations (Scopus)

New developments in the pathogenesis of obesity-induced hypertension

Kotsis, V., Nilsson, P., Grassi, G., Mancia, G., Redon, J., Luft, F., Schmieder, R., Engeli, S., Stabouli, S., Antza, C., Pall, D., Schlaich, M. & Jordan, J., 2015, In : Journal of Hypertension. 33, 8, p. 1499-1508

Research output: Contribution to journalArticle

48 Citations (Scopus)

Opposing effects of shear-mediated dilation and myogenic constriction on artery diameter in response to handgrip exercise in humans

Atkinson, C., Carter, H., Naylor, L., Dawson, E. A., Marusic, P., Hering, D., Schlaich, M., Thijssen, D. H. J. & Green, D. J., 15 Oct 2015, In : Journal of Applied Physiology. 119, 8, p. 858-864 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
310 Downloads (Pure)

Pioglitazone treatment enhances the sympathetic nervous system response to oral carbohydrate load in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Richards, K., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Jul 2015, In : Metabolism: clinical and experimental. 64, 7, p. 797-803 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Reduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss

Straznicky, N. E., Grima, M. T., Sari, C. I., Lambert, E. A., Phillips, S. E., Eikelis, N., Kobayashi, D., Hering, D., Mariani, J. A., Dixon, J. B., Nestel, P. J., Karapanagiotidis, S., Schlaich, M. P. & Lambert, G. W., 22 Aug 2015, In : Cardiovascular Diabetology. 14, 1, 113.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Reinnervation following catheter-based radio-frequency renal denervation

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 20 Apr 2015, In : Experimental Physiology. 100, 5, p. 485-490 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Reinnervation of renal afferent and efferent nerves at 5.5 and 11 months after catheter-based radiofrequency renal denervation in sheep

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 21 Feb 2015, In : Hypertension. 65, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

Open Access
78 Citations (Scopus)

Relevance of sympathetic nervous system activation in obesity and metabolic syndrome

Thorp, A. A. & Schlaich, M., 2015, In : Journal of Diabetes Research. 2015, p. 1-11

Research output: Contribution to journalArticle

Open Access
File
123 Citations (Scopus)
179 Downloads (Pure)

Renal denervation: Potential future implications beyond resistant hypertension

Schlaich, M. P., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. New York: Springer-Verlag London Ltd., p. 155-161 7 p.

Research output: Chapter in Book/Conference paperChapter

Renal denervation: A new approach to treatment of resistant hypertension

Heuser, R. R. (ed.), Schlaich, M. (ed.) & Sievert, H. (ed.), 2015, New York: Springer-Verlag London Ltd. 201 p.

Research output: Book/ReportBook

Renal Sympathetic Denervation

Schlaich, M., 2015, Chronic Kidney Disease and Hypertension. Weir, M. R. & Lerma, E. V. (eds.). New York: Humana Press, p. 69-81

Research output: Chapter in Book/Conference paperChapter

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering

Mclellan, A. J. A., Schlaich, M., Taylor, A. J., Prabhu, S. G. S., Hering, D., Hammond, L., Marusic, P., Duval, J., Sata, Y., Ellims, A. H., Esler, M. D., Peter, K., Shaw, J. A., Walton, A. S., Kalman, J. M. & Kistler, P. M., 1 May 2015, In : Heart Rhythm. 12, 5, p. 982-990

Research output: Contribution to journalArticle

37 Citations (Scopus)

Role of the Sympathetic Nervous System in Stress-Mediated Cardiovascular Disease

Hering, D., Lachowska, K. & Schlaich, M., Oct 2015, In : Current Hypertension Reports. 17, 10, p. 1-9 9 p., 80.

Research output: Contribution to journalReview article

28 Citations (Scopus)

Short-term effects of catheter-based renal denervation on cardiac sympathetic drive and cardiac baroreflex function in heart failure

Booth, L. C., Schlaich, M. P., Nishi, E. E., Yao, S. T., Xu, J., Ramchandra, R., Lambert, G. W. & May, C. N., 1 Jul 2015, In : International Journal of Cardiology. 190, 1, p. 220-226 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
33 Downloads (Pure)

Sympathetic activation and endothelial dysfunction in polycystic ovary syndrome are not explained by either obesity or insulin resistance

Lambert, E. A., Teede, H., Sari, C. I., Jona, E., Shorakae, S., Woodington, K., Hemmes, R., Eikelis, N., Straznicky, N. E., De Courten, B., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Dec 2015, In : Clinical Endocrinology. 83, 6, p. 812-819 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The effect of renal denervation on endothelial function and inflammatory markers in patients with resistant hypertension

Eikelis, N., Hering, D., Marusic, P., Sari, C., Walton, A., Phillips, S., Lambert, E., Duval, J., Krum, H., Lambert, G., Esler, M. & Schlaich, M., Aug 2015, In : International Journal of Cardiology. 188, 1, p. 96-98 3 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)

The potential role of catheter-based renal sympathetic denervation in chronic and end-stage kidney disease

Schlaich, M. P. & Sata, Y., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. Springer-Verlag London Ltd., p. 181-189 9 p.

Research output: Chapter in Book/Conference paperChapter

The Role of Central Nervous System Mechanisms in Resistant Hypertension

Hering, D. & Schlaich, M., Aug 2015, In : Current Hypertension Reports. 17, 58, p. 1-9

Research output: Contribution to journalReview article

Open Access
File
16 Citations (Scopus)
218 Downloads (Pure)
2014

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K. C., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N. E., Kingwell, B. A. & De Courten, B., 1 Feb 2014, In : Amino Acids. 46, 2, p. 321-326 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

A randomized controlled trial of the effects of pioglitazone treatment on sympathetic nervous system activity and cardiovascular function in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Karapanagiotidis, S., Wong, C., Richards, K., Marusic, P., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. E1701-E1707

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Association of vitamin D status and blood pressure response after renal denervation

Pöss, J., Mahfoud, F., Ukena, C., Esler, M. D., Schlaich, M., Hering, D., Cremers, B., Laufs, U. & Böhm, M., 2014, In : Clinical Research in Cardiology. 103, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 2014, In : The Lancet. 383, 9932, p. 1885-1886 2 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Baroreflex sensitivity: A reliable predictor of response to renal denervation?

Hering, D., Esler, M. D. & Schlaich, M. P., 15 Jul 2014, In : Journal of the American College of Cardiology. 64, 2, p. 232-233 2 p.

Research output: Contribution to journalLetter

Open Access

Biomarkers for the prediction of blood pressure response to renal denervation: A long way to go

Schlaich, M., 2014, In : Hypertension. 63, 5, p. 907-908 2 p.

Research output: Contribution to journalComment/debate

Open Access
4 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
157 Citations (Scopus)

Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: The SABPA Study

Malan, N. T., Stalder, T., Schlaich, M. P., Lambert, G. W., Hamer, M., Schutte, A. E., Huisman, H. W., Schutte, R., Smith, W., Mels, C. M. C., Van Rooyen, J. M. & Malan, L., Jun 2014, In : Journal of Human Hypertension. 28, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Critical issues in patient selection, efficacy, and safety of renal denervation

Schlaich, M. P., Esler, M. D., Fink, G. D., Osborn, J. W. & Euler, D. E., Mar 2014, In : Hypertension. 63, 3, p. 426-432 7 p.

Research output: Contribution to journalReview article

Open Access
26 Citations (Scopus)

CrossTalk opposing view: Which technique for controlling resistant hypertension? Renal nerve ablation

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, p. 3937-3940 4 p.

Research output: Contribution to journalComment/debate

Open Access
5 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
92 Citations (Scopus)

From symplicity htn-3 to the renal denervation global registry: Where do we stand and where should we go

Pathak, A., Ewen, S., Fajadet, J., Honton, B., Mahfoud, F., Marco, J., Schlaich, M., Schmieder, R., Tsioufis, K., Ukena, C. & Zeller, T., 2014, In : EuroIntervention. 10, p. 21

Research output: Contribution to journalReview article

31 Citations (Scopus)

Hypertension: Treatment-resistant hypertension-A risk factor for ESRD

Schlaich, M. P., 2014, In : Nature Reviews Nephrology. 10, 4, p. 189-190 2 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)