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  • Keith Stubbs
2018

A herbicide structure–activity analysis of the antimalarial lead compound MMV007978 against Arabidopsis thaliana

Corral, M. G., Leroux, J., Tresch, S., Newton, T., Stubbs, K. A. & Mylne, J. S., 1 Jul 2018, In : Pest Management Science. 74, 7, p. 1558-1563 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2019

East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide

Li, H., Marceau, M., Yang, T., Liao, T., Tang, X., Hu, R., Xie, Y., Tang, H., Tay, A., Shi, Y., Shen, Y., Yang, T., Pi, X., Lamichhane, B., Luo, Y., Debowski, A. W., Nilsson, H. O., Haslam, S. M., Mulloy, B., Dell, A. & 3 others, Stubbs, K. A., Marshall, B. J. & Benghezal, M., 1 Jan 2019, In : PLoS Genetics. 15, 11, e1008497.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Synthetic and Crystallographic Insight into Exploiting sp2 Hybridization in the Development of α-l-Fucosidase Inhibitors

Coyle, T., Wu, L., Debowski, A. W., Davies, G. J. & Stubbs, K. A., 3 Jun 2019, In : ChemBioChem. 20, 11, p. 1365-1368 4 p.

Research output: Contribution to journalArticle

Open Access
2018

Integrating thin film microfluidics in developing a concise synthesis of DGJNAc: A potent inhibitor of α-N-acetylgalctosaminidases

Wills, S. S., Raston, C. L. & Stubbs, K. A., 15 Dec 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 23-24, p. 3748-3751 4 p.

Research output: Contribution to journalArticle

2020

Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates

Hattie, M. & Stubbs, K. A., 16 Jan 2020, In : ChemistrySelect. 5, 2, p. 875-877 3 p.

Research output: Contribution to journalArticle

2018

Potent inhibition of a GH20 exo-β-N-acetylglucosaminidase from marine Vibrio bacteria by reaction intermediate analogues

Meekrathok, P., Stubbs, K. A. & Suginta, W., 1 Aug 2018, In : International Journal of Biological Macromolecules. 115, p. 1165-1173 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
147 Downloads (Pure)
2016

Modifying the phenyl group of PUGNAc: Reactivity tuning to deliver selective inhibitors for N-acetyl-d-glucosaminidases

Hattie, M., Cekic, N., Debowski, A., Vocadlo, D. J. & Stubbs, K., 23 Feb 2016, In : Organic and Biomolecular Chemistry. 14, 12, p. 3193-3197

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
272 Downloads (Pure)
2018

Chemical Ecogenomics-Guided Discovery of Phytotoxic α-Pyrones from the Fungal Wheat Pathogen Parastagonospora nodorum

Li, H., Hu, J., Wei, H., Solomon, P. S., Vuong, D., Lacey, E., Stubbs, K. A., Piggott, A. M. & Chooi, Y. H., 5 Oct 2018, In : Organic Letters. 20, 19, p. 6148-6152 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Angled Vortex Fluidic Mediated Multicomponent Photocatalytic and Transition Metal-Catalyzed Reactions

Ho, L. A., Raston, C. L. & Stubbs, K. A., 21 Jun 2018, In : Chemistry - A European Journal. 24, 35, p. 8869-8874 6 p.

Research output: Contribution to journalArticle

File
5 Citations (Scopus)
206 Downloads (Pure)
2016

Lipopolysaccharide Structure and Biosynthesis in Helicobacter pylori

Li, H., Liao, T., Debowski, A., Tang, H., Nilsson, H. O., Stubbs, K. A., Marshall, B. J. & Benghezal, M., 1 Dec 2016, In : Helicobacter. 21, 6, p. 445-461 17 p.

Research output: Contribution to journalReview article

Open Access
File
21 Citations (Scopus)
463 Downloads (Pure)
2019

Biosynthesis of a Tricyclo[6.2.2.02,7]dodecane System by a Berberine Bridge Enzyme-Like Aldolase

Li, H., Hu, J., Wei, H., Solomon, P. S., Stubbs, K. A. & Chooi, Y. H., 25 Sep 2019, In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system

Hu, J., Sarrami, F., Li, H., Zhang, G., Stubbs, K. A., Lacey, E., Stewart, S. G., Karton, A., Piggott, A. M. & Chooi, Y-H., 7 Feb 2019, In : Chemical Science. 10, 5, p. 1457-1465 9 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
2020

Syntheses and biological investigations of kirkamide and oseltamivir hybrid derivatives

Sieber, S., Hsiao, C. C., Emmanouilidou, D., Debowski, A. W., Stubbs, K. A. & Gademann, K., 14 Jul 2020, In : Tetrahedron. 131386.

Research output: Contribution to journalArticle

Open Access
2016

Transition-Metal-Free Cross-Coupling Reactions in Dynamic Thin Films To Access Pyrimidine and Quinoxaline Analogues

Ho, L. A., Raston, C. L. & Stubbs, K. A., Dec 2016, In : European Journal of Organic Chemistry. 2016, 36, p. 5957-5963

Research output: Contribution to journalArticle

7 Citations (Scopus)
2018

Enzyme targets for drug design of new anti-virulence therapeutics

Kahler, C. M., Sarkar-Tyson, M., Kibble, E. A., Stubbs, K. A. & Vrielink, A., 1 Dec 2018, In : Current Opinion in Structural Biology. 53, p. 140-150 11 p.

Research output: Contribution to journalReview article

Open Access
File
3 Citations (Scopus)
439 Downloads (Pure)

Lipopolysaccharide structural differences between western and Asian Helicobacter pylori strains

Li, H., Tang, H., Debowski, A. W., Stubbs, K. A., Marshall, B. J. & Benghezal, M., 8 Sep 2018, In : Toxins. 10, 9, 364.

Research output: Contribution to journalReview article

Open Access
5 Citations (Scopus)

Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

Wallace, M. D., Waraich, N. F., Debowski, A. W., Corral, M. G., Maxwell, A., Mylne, J. S. & Stubbs, K. A., 21 Feb 2018, In : Chemical Communications. 54, 15, p. 1869-1872 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut

Hemsworth, G. R., Thompson, A. J., Stepper, J., Sobala, T. F., Coyle, T., Larsbrink, J., Spadiut, O., Goddard-Borger, E. D., Stubbs, K., Brumer, H. & Davies, G. J., 27 Jul 2016, In : Open Biology. 6, 7, p. 1-14

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)
2018

Targeting plant DIHYDROFOLATE REDUCTASE with antifolates and mechanisms for genetic resistance

Corral, M. G., Haywood, J., Stehl, L. H., Stubbs, K. A., Murcha, M. W. & Mylne, J. S., 1 Aug 2018, In : Plant Journal. 95, 4, p. 727-742 16 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
201 Downloads (Pure)
2016

A Fluorescent Transport Assay Enables Studying AmpG Permeases Involved in Peptidoglycan Recycling and Antibiotic Resistance

Perley-Robertson, G. E., Yadav, A. K., Winogrodzki, J. L., Stubbs, K., Mark, B. L. & Vocadlo, D. J., 2016, In : ACS Chemical Biology. 11, 9, p. 2626-2635

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)
2019

General Synthesis of 3,4-Dinitrophenyl α-Glycopyranosides

Wallace, M. D. & Stubbs, K. A., 24 Oct 2019, In : ChemistrySelect. 4, 39, p. 11427-11429 3 p.

Research output: Contribution to journalArticle

Open Access
File
302 Downloads (Pure)
2018

A mechanism-based GlcNAc-inspired cyclophellitol inactivator of the peptidoglycan recycling enzyme NagZ reverses resistance to β-lactams in Pseudomonas aeruginosa

Ho, L. A., Winogrodzki, J. L., Debowski, A. W., Madden, Z., Vocadlo, D. J., Mark, B. L. & Stubbs, K. A., 1 Jan 2018, In : Chemical Communications. 54, 75, p. 10630-10633 4 p.

Research output: Contribution to journalArticle

File
3 Citations (Scopus)
318 Downloads (Pure)
2016

Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by human: O-GlcNAcase

Cekic, N., Heinonen, J. E., Stubbs, K., Roth, C., He, Y., Bennet, A. J., Mceachern, E. J., Davies, G. J. & Vocadlo, D. J., 2016, In : Chemical Science. 7, 6, p. 3742-3750

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)
2020

Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum

Li, H., Wei, H., Hu, J., Lacey, E., Sobolev, A. N., Stubbs, K. A., Solomon, P. S. & Chooi, Y. H., 17 Jan 2020, In : ACS Chemical Biology. 15, 1, p. 226-233

Research output: Contribution to journalArticle

2018

Structure of a Talaromyces pinophilus GH62 arabinofuranosidase in complex with AraDNJ at 1.25A° resolution

Moroz, O. V., Sobala, L. F., Blagova, E., Coyle, T., Peng, W., Krogh, K. B. R. M., Stubbs, K. A., Wilson, K. S. & Davies, G. J., 1 Aug 2018, In : Acta Crystallographica Section F: Structural Biology Communications. 74, 8, p. 490-495 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)