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  • Jiake Xu
2016

Neurotrophin-3 Induces BMP-2 and VEGF Activities and Promotes the Bony Repair of Injured Growth Plate Cartilage and Bone in Rats

Su, Y., Chung, R., Ruan, C., Chim, S., Kuek, V., Dwivedi, P., Hassanshahi, M., Chen, K., Xie, Y., Chen, L., Foster, B., Rosen, V., Zhou, X., Xu, J. & Xian, C., Jun 2016, In : Journal of Bone & Mineral Research. 31, 6, p. 1258-1274

Research output: Contribution to journalArticle

24 Citations (Scopus)

Treadmill running exercise prevents senile osteoporosis and upregulates the Wnt signaling pathway in SAMP6 mice

Chen, X., Li, L., Guo, J., Zhang, L., Yuan, Y., Chen, B., Sun, Z., Xu, J. & Zou, J., 2016, In : Oncotarget. 7, 44, p. 71072-71086 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Sinomenine down-regulates TLR4/TRAF6 expression and attenuates lipopolysaccharide-induced osteoclastogenesis and osteolysis

He, L., Duan, H., Li, X., Wang, S., Zhang, Y., Lei, L., Xu, J. & Liu, S., 2016, In : European Journal of Pharmacology. 779, p. 66-79

Research output: Contribution to journalArticle

12 Citations (Scopus)

Folate-targeting redox hyperbranched poly(amido amine)s delivering MMP-9 siRNA for cancer therapy

Li, M., Zhou, X., Zeng, X., Wang, C., Xu, J., Ma, D. & Xue, W., 2016, In : Journal of Materials Chemistry B. 4, 3, p. 547-556

Research output: Contribution to journalArticle

32 Citations (Scopus)

Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation

Liu, Q., Wang, T., Zhou, L., Song, F., Qin, A., Feng, H. T., Lin, X. X., Lin, Z., Yuan, J. B., Tickner, J., Liu, H. G., Zheng, M. H., Xu, J. & Zhao, J. M., 8 Nov 2016, In : Scientific Reports. 6, p. 1-10 36662 .

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Calmodulin interacts with Rab3D and modulates osteoclastic bone resorption

Zhu, S., Chim, S. M., Cheng, T., Ang, E., Ng, B., Lim, B., Chen, K., Qiu, H., Tickner, J., Xu, H., Pavlos, N. & Xu, J., 29 Nov 2016, In : Scientific Reports. 6, p. 1-9

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2017

The Emerging Role of MORC Family Proteins in Cancer Development and Bone Homeostasis

Hong, G., Qiu, H., Wang, C., Jadhav, G., Wang, H., Tickner, J., He, W. & Xu, J., 1 May 2017, In : Journal of Cellular Physiology. 232, 5, p. 928-934 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2019

Daphnetin attenuates LPS-induced osteolysis and RANKL mediated osteoclastogenesis through suppression of ERK and NFATc1 pathways

Wu, Z., Wu, H., Li, C., Fu, F., Ding, J., Shao, S., Li, K., Yu, X., Su, Y., Liang, J., Lin, X., Yuan, G., Zhou, J., Song, F., Zhao, J., Xu, J., Liu, Q. & Xu, F., 1 Oct 2019, In : Journal of Cellular Physiology. 234, 10, p. 17812-17823 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Molecular structure and the role of high-temperature requirement protein 1 in skeletal disorders and cancers

Li, Y., Yuan, J., Rothzerg, E., Wu, X., Xu, H., Zhu, S. & Xu, J., 22 Dec 2019, In : Cell Proliferation. e12746.

Research output: Contribution to journalReview article

Open Access
2018
17 Citations (Scopus)
2019

Double network shape memory hydrogels activated by near-infrared with high mechanical toughness, nontoxicity, and 3D printability

Dai, W., Guo, H., Gao, B., Ruan, M., Xu, L., Wu, J., Kirk, T. B., Xu, J., Ma, D. & Xue, W., 15 Jan 2019, In : Chemical Engineering Journal. 356, p. 934-949 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Helvolic acid attenuates osteoclast formation and function via suppressing RANKL-induced NFATc1 activation

Chen, K., Yuan, Y., Wang, Z., Song, D., Zhao, J., Cao, Z., Chen, J., Guo, Q., Chen, L., Tickner, J. & Xu, J., May 2019, In : Journal of Cellular Physiology. 234, 5, p. 6477-6488 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
12 Downloads (Pure)
2017

Molecular structure and differential function of choline kinases CHKα and CHKβ in musculoskeletal system and cancer

Chen, X., Qiu, H., Wang, C., Yuan, Y., Tickner, J., Xu, J. & Zou, J., Feb 2017, In : Cytokine and Growth Factor Reviews. 33, p. 65-72 8 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
269 Downloads (Pure)
2018

Redox-responsive chemosensitive polyspermine delivers ursolic acid targeting to human breast tumor cells: The depletion of intracellular GSH contents arouses chemosensitizing effects

Ji, X., Tang, Q., Pang, P., Wu, J., Kirk, T. B., Xu, J., Ma, D. & Xue, W., 1 Oct 2018, In : Colloids and Surfaces B: Biointerfaces. 170, p. 293-302 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

A005, a novel inhibitor of phosphatidylinositol 3-kinase/mammalian target of rapamycin, prevents osteosarcoma-induced osteolysis

Lian, Z., Han, J., Huang, L., Wei, C., Fan, Y., Xu, J., Zhou, M., Feng, H., Liu, Q., Chen, L., Li, Z., Cheng, H., Yuan, G., Lin, X., Song, F., Su, Y., Wang, C., Huang, G., Qin, A., Song, Y. & 1 others, Yao, G., 1 Jan 2019, In : Carcinogenesis. 40, 2, p. E1-E13

Research output: Contribution to journalArticle

2 Citations (Scopus)

Cytochalasin Z11 inhibits RANKL-induced osteoclastogenesis: Via suppressing NFATc1 activation

Wang, L., Chen, K., He, J., Kenny, J., Yuan, Y., Chen, J., Liu, Q., Tan, R., Zhao, J. & Xu, J., 25 Nov 2019, In : RSC Advances. 9, 66, p. 38438-38446 9 p.

Research output: Contribution to journalArticle

Open Access
2018

Macrophages release plasma membrane-derived particles rich in accessible cholesterol

He, C., Hu, X., Weston, T. A., Jung, R. S., Sandhu, J., Huang, S., Heizer, P., Kim, J., Ellison, R., Xu, J., Kilburn, M., Bensinger, S. J., Riezman, H., Tontonoz, P., Fong, L. G., Jiang, H. & Young, S. G., 4 Sep 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 36, p. E8499-E8508

Research output: Contribution to journalArticle

6 Citations (Scopus)
2019

Osthole inhibits osteoclasts formation and bone resorption by regulating NF-κB signaling and NFATc1 activations stimulated by RANKL

Ma, Y., Wang, L., Zheng, S., Xu, J., Pan, Y., Tu, P., Sun, J. & Guo, Y., 1 Sep 2019, In : Journal of Cellular Biochemistry. 120, 9, p. 16052-16061 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Bajijiasu abrogates osteoclast differentiation via the suppression of RANKL signaling pathways through NF-κB and NFAT

Hong, G., Zhou, L., Shi, X., He, W., Wang, H., Wei, Q., Chen, P., Qi, L., Tickner, J., Lin, L. & Xu, J., 19 Jan 2017, In : International Journal of Molecular Sciences. 18, 1, 12 p., 203.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Natural Compounds for the Treatment of Psoriatic Arthritis: A Proposal Based on Multi-Targeted Osteoclastic Regulation and on a Preclinical Study

Deng, S., Cheng, J., Zhao, J., Yao, F. & Xu, J., 11 Jul 2017, In : JMIR Research Protocols. 6, 7, e132.

Research output: Contribution to journalArticle

Open Access
2019

The Effect of Exercise on the Prevention of Osteoporosis and Bone Angiogenesis

Tong, X., Chen, X., Zhang, S., Huang, M., Shen, X., Xu, J. & Zou, J., 2019, In : BioMed Research International. 2019, 8 p., 8171897.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

Cajaninstilbene acid inhibits osteoporosis through suppressing osteoclast formation and RANKL-induced signaling pathways

Sun, Y., Liu, Y., He, W., Wang, C., Tickner, J., Kuek, V., Zhou, C., Wang, H., Zou, X., Hong, Z., Yang, F., Shao, M., Chen, L. & Xu, J., 1 Jul 2019, In : Journal of Cellular Physiology. 234, 7, p. 11792-11804 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2019

Dehydrocostus lactone (DHC) suppresses estrogen deficiency-induced osteoporosis

Li, Z., Yuan, G., Lin, X., Liu, Q., Xu, J., Lian, Z., Song, F., Zheng, J., Xie, D., Chen, L., Wang, X., Feng, H., Zhou, M. & Yao, G., 1 May 2019, In : Biochemical Pharmacology. 163, p. 279-289 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Monocrotaline Suppresses RANKL-Induced Osteoclastogenesis in Vitro and Prevents LPS-Induced Bone Loss in Vivo

Wei, C. M., Su, Y. J., Qin, X., Ding, J. X., Liu, Q., Song, F. M., Zong, S. H., Xu, J., Zhou, B. & Zhao, J. M., 1 Aug 2018, In : Cellular Physiology and Biochemistry. 48, 2, p. 644-656 13 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2019

PIP5k1 beta controls bone homeostasis through modulating both osteoclast and osteoblast differentiation

Zhao, X., Cui, P., Wang, C., Zhao, J., Zhang, X. & Xu, J., Dec 2019, In : Journal of Bone and Mineral Research. 34, p. 328-328 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2018

Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways

Cheng, J., Zhou, L., Liu, Q., Tickner, J., Tan, Z., Li, X., Liu, M., Lin, X., Wang, T., Pavlos, N. J., Zhao, J. & Xu, J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2502-2512 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2020

Jatrophane Diterpenoids from Euphorbia esula as Inhibitors of RANKL-Induced Osteoclastogenesis

Yuan, S., Hua, P., Zhao, C., Zhou, H., Xu, J., Xu, J. & Gu, Q., 1 Jan 2020, (Accepted/In press) In : Journal of Natural Products.

Research output: Contribution to journalArticle

2018

Synthesis of Janus Au nanorods/polydivinylbenzene hybrid nanoparticles for chemo-photothermal therapy

Wang, Y., Ji, X., Pang, P., Shi, Y., Dai, J., Xu, J., Wu, J., Kirk, T. B. & Xue, W., 28 Apr 2018, In : Journal of Materials Chemistry B. 6, 16, p. 2481-2488 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2019

MiR-214 is an important regulator of the musculoskeletal metabolism and disease

Sun, Y., Kuek, V., Liu, Y., Tickner, J., Yuan, Y., Chen, L., Zeng, Z., Shao, M., He, W. & Xu, J., Jan 2019, In : Journal of Cellular Physiology. 234, 1, p. 231-245 15 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

Liu, Y., Wang, C., Wang, G., Sun, Y., Deng, Z., Chen, L., Chen, K., Tickner, J., Kenny, J., Song, D., Zhang, Q., Wang, H., Chen, Z., Zhou, C., He, W. & Xu, J., 2019, In : Theranostics. 9, 16, p. 4648-4662 15 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Pectolinarigenin prevents bone loss in ovariectomized mice and inhibits RANKL-induced osteoclastogenesis via blocking activation of MAPK and NFATc1 signaling

Xiao, Y., Li, K., Wang, Z., Fu, F., Shao, S., Song, F., Zhao, J., Chen, W., Liu, Q. & Xu, J., 1 Aug 2019, In : Journal of Cellular Physiology. 234, 8, p. 13959-13968 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

MiR-214 Attenuates the Osteogenic Effects of Mechanical Loading on Osteoblasts

Yuan, Y., Guo, J., Zhang, L., Tong, X., Zhang, S., Zhou, X., Zhang, M., Chen, X., Lei, L., Li, H., Liu, T. C. Y., Xu, J. & Zou, J., Dec 2019, In : International Journal of Sports Medicine. 40, 14, p. 931-940 10 p.

Research output: Contribution to journalArticle

2017

Differential protein expression between normal and degenerated human nucleus pulposus cells by proteomic and bioinformatics analyses

Ye, D. P., Liang, W. G., Dai, L., Yao, Y., Chen, H., Zhou, Y. & Xu, J., 2017, In : International Journal of Clinical and Experimental Medicine. 10, 12, p. 16172-16180 9 p.

Research output: Contribution to journalArticle

Open Access
File
56 Downloads (Pure)

Injectable supramolecular hydrogel formed from α-cyclodextrin and PEGylated arginine-functionalized poly(L-lysine) dendron for sustained MMP-9 shRNA plasmid delivery

Lin, Q., Yang, Y., Hu, Q., Guo, Z., Liu, T., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Feb 2017, In : Acta Biomaterialia. 49, p. 456-471 16 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2018

Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats

Su, Y. W., Chim, S. M., Zhou, L., Hassanshahi, M., Chung, R., Fan, C., Song, Y., Foster, B. K., Prestidge, C. A., Peymanfar, Y., Tang, Q., Butler, L. M., Gronthos, S., Chen, D., Xie, Y., Chen, L., Zhou, X. F., Xu, J. & Xian, C. J., 1 Nov 2018, In : Bone. 116, p. 232-247 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2019

The emerging roles of hnRNPK

Wang, Z., Qiu, H., He, J., Liu, L., Xue, W., Fox, A., Tickner, J. & Xu, J., 19 Sep 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2016
2020

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

Mullin, B., Tickner, J., Zhu, K., Kenny, J., Mullin, S., Brown, S. J., Dudbridge, F., Pavlos, N., Mocarski, E. S., Walsh, J. P., Xu, J. & Wilson, S., 26 Mar 2020, In : Genome Biology. 21, 80.

Research output: Contribution to journalArticle

Open Access
2017

Hemostasis mechanism and applications of N-alkylated chitosan sponge

Huang, Y., Feng, L., Zhang, Y., He, L., Wang, C., Xu, J., Wu, J., Kirk, T. B., Guo, R. & Xue, W., 1 Sep 2017, In : Polymers for Advanced Technologies. 28, 9, p. 1107-1114 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Three dimensional microstructural network of elastin, collagen, and cells in Achilles tendons

Pang, X., Wu, J-P., Allison, G. T., Xu, J., Rubenson, J., Zheng, M-H., Lloyd, D. G., Gardiner, B., Wang, A. & Kirk, T. B., Jun 2017, In : Journal of Orthopaedic Research. 35, 6, p. 1203-1214

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
95 Downloads (Pure)

Massage alleviates delayed onset muscle soreness after strenuous exercise: A systematic review and meta-analysis

Guo, J., Li, L., Gong, Y., Zhu, R., Xu, J., Zou, J. & Chen, X., 27 Sep 2017, In : Frontiers in Physiology. 8, 747.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)
2019

Sclareol prevents ovariectomy-induced bone loss: In vivo and inhibits osteoclastogenesis in vitro via suppressing NF-κB and MAPK/ERK signaling pathways

Jin, H., Shao, Z., Wang, Q., Miao, J., Bai, X., Liu, Q., Qiu, H., Wang, C., Zhang, Z., Jennifer, T., Wang, X. & Xu, J., 1 Oct 2019, In : Food and Function. 10, 10, p. 6556-6567 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pseurotin A inhibits osteoclastogenesis and prevents ovariectomized-induced bone loss by suppressing reactive oxygen species

Chen, K., Qiu, P., Yuan, Y., Zheng, L., He, J., Wang, C., Guo, Q., Kenny, J., Liu, Q., Zhao, J., Chen, J., Tickner, J., Fan, S., Lin, X. & Xu, J., 28 Feb 2019, In : Theranostics. 9, 6, p. 1634-1650

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
378 Downloads (Pure)
2016

Current research on pharmacologic and regenerative therapies for osteoarthritis

Zhang, W., Ouyang, H., Dass, C. R. & Xu, J., 1 Mar 2016, In : Bone Research. 4, p. 1-14 14 p., 15040 .

Research output: Contribution to journalReview article

Open Access
128 Citations (Scopus)
2018

Achyranthes bidentata polysaccharide suppresses osteoclastogenesis and bone resorption via inhibiting RANKL signaling

Song, D., Cao, Z., Huang, S., Tickner, J., Li, N., Qiu, H., Chen, X., Wang, C., Chen, K., Sun, Y., Dong, S. & Xu, J., 1 Jun 2018, In : Journal of Cellular Biochemistry. 119, 6, p. 4826-4835 10 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
318 Downloads (Pure)
2016

Star-Shaped Amphiphilic Hyperbranched Polyglycerol Conjugated with Dendritic Poly(L-lysine) for the Codelivery of Docetaxel and MMP-9 siRNA in Cancer Therapy

Zhou, X., Zheng, Q., Wang, C., Xu, J., Wu, J. P., Kirk, T. B., Ma, D. & Xue, W., 2016, In : ACS Applied Materials and Interfaces. 8, 20, p. 12609-12619 11 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Deficiency of sorting nexin 10 prevents bone erosion in collagen-induced mouse arthritis through promoting NFATc1 degradation

Zhou, C., You, Y., Shen, W., Zhu, Y. Z., Peng, J., Feng, H. T., Wang, Y., Li, D., Shao, W. W., Li, C. X., Li, W. Z., Xu, J. & Shen, X., 2016, In : Annals of the Rheumatic Diseases. n/a, p. 1-8

Research output: Contribution to journalArticle

14 Citations (Scopus)

The y6 receptor suppresses bone resorption and stimulates bone formation in mice via a suprachiasmatic nucleus relay

Khor, E. C., Yulyaningsih, E., Driessler, F., Kovaĉić, N., Wee, N. K. Y., Kulkarni, R. N., Lee, N. J., Enriquez, R. F., Xu, J., Zhang, L., Herzog, H. & Baldock, P. A., Mar 2016, In : Bone. 84, p. 139-147 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
5 Citations (Scopus)