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  • 2020
  • 2019
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  • 2016

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  • Mark Nicol
2020

Chronic lung disease in children and adolescents with HIV: a case–control study

the BREATHE Clinical Trial Team, 1 Jan 2020, In : Tropical Medicine and International Health.

Research output: Contribution to journalArticle

2019

Guidance for Studies Evaluating the Accuracy of Sputum-Based Tests to Diagnose Tuberculosis

Schumacher, S. G., Wells, W. A., Nicol, M. P., Steingart, K. R., Theron, G., Dorman, S. E., Pai, M., Churchyard, G., Scott, L., Stevens, W., Nabeta, P., Alland, D., Weyer, K., Denkinger, C. M. & Gilpin, C., 8 Oct 2019, In : The Journal of infectious diseases. 220, S3, p. S99-S107

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Highly sensitive sequence specific qPCR detection of Mycobacterium tuberculosis complex in respiratory specimens

Reed, J. L., Walker, Z. J., Basu, D., Allen, V., Nicol, M. P., Kelso, D. M. & McFall, S. M., 1 Dec 2016, In : Tuberculosis. 101, p. 114-124 11 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
2020

Composition of gut microbiota of children and adolescents with perinatal HIV infection taking antiretroviral therapy in Zimbabwe

Breathe Study Team, 14 Jan 2020, In : The Journal of infectious diseases. 221, 3, p. 483-492

Research output: Contribution to journalArticle

Open Access
File
7 Downloads (Pure)
2019

Association of maternal prenatal psychological stressors and distress with maternal and early infant faecal bacterial profile

Naudé, P. J. W., Claassen-Weitz, S., Gardner-Lubbe, S., Botha, G., Kaba, M., Zar, H. J., Nicol, M. P. & Stein, D. J., 22 Nov 2019, In : Acta Neuropsychiatrica. p. 1-31 31 p.

Research output: Contribution to journalArticle

Open Access
File
45 Downloads (Pure)
2020

The Influence of DNA Extraction and Lipid Removal on Human Milk Bacterial Profiles

Ojo-Okunola, A., Claassen-Weitz, S., Mwaikono, K. S., Gardner-Lubbe, S., Zar, H. J., Nicol, M. P. & du Toit, E., 15 May 2020, In : Methods and protocols. 3, 2

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2016

Diagnostic accuracy of lateral flow urine LAM assay for TB screening of adults with advanced immunosuppression attending routine HIV care in South Africa

Hanifa, Y., Fielding, K. L., Chihota, V. N., Adonis, L., Charalambous, S., Karstaedt, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Sahid, F., Churchyard, G. J. & Grant, A. D., 1 Jun 2016, In : PLoS One. 11, 6, e0156866.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)
2018

Serologic Responses in Childhood Pulmonary Tuberculosis

Nonyane, B. A. S., Nicol, M. P., Andreas, N. J., Rimmele, S., Schneiderhan-Marra, N., Workman, L. J., Perkins, M. D., Joos, T., Broger, T., Ellner, J. J., Alland, D., Kampmann, B., Dorman, S. E. & Zar, H. J., 1 Jan 2018, In : Pediatric Infectious Disease Journal. 37, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Precision medicine for drug-resistant tuberculosis in high-burden countries: is individualised treatment desirable and feasible?

Cox, H., Hughes, J., Black, J. & Nicol, M. P., 1 Sep 2018, In : The Lancet Infectious Diseases. 18, 9, p. e282-e287

Research output: Contribution to journalReview article

17 Citations (Scopus)
2020

Accuracy of a novel urine test, Fujifilm SILVAMP TB LAM, for the diagnosis of pulmonary tuberculosis in children

Nicol, M. P., Schumacher, S. G., Workman, L., Broger, T., Baard, C., Prins, M., Bateman, L., du Toit, E., van Heerden, J., Szekely, R., Zar, H. J. & Denkinger, C. M., 6 Aug 2020, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Research output: Contribution to journalArticle

2019

Strengthening Diagnosis of Pulmonary Tuberculosis in Children: The Role of Xpert MTB/RIF Ultra

Zar, H. J. & Nicol, M. P., 1 Nov 2019, In : Pediatrics. 144, 5

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Fecal carriage of Staphylococcus aureus in the hospital and community setting: A systematic review

Claassen-Weitz, S., Shittu, A. O., Ngwarai, M. R., Thabane, L., Nicol, M. P. & Kaba, M., 1 Jan 2016, In : Frontiers in Microbiology. 7, MAY, 449.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)
2018

Age-related waning of immune responses to BCG in healthy children supports the need for a booster dose of BCG in TB endemic countries

Whittaker, E., Nicol, M. P., Zar, H. J., Tena-Coki, N. G. & Kampmann, B., 1 Dec 2018, In : Scientific Reports. 8, 1, 15309.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tuberculin skin test conversion and primary progressive tuberculosis disease in the first 5 years of life: a birth cohort study from Cape Town, South Africa

Martinez, L., le Roux, D. M., Barnett, W., Stadler, A., Nicol, M. P. & Zar, H. J., 1 Jan 2018, In : The Lancet Child & Adolescent Health. 2, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
2016

A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries

HIV Network Coordinating (HANC) TB Diagnostic Laboratory Working Division of AIDS, National Institute of Allergy and Infectious Diseases, 10 Jun 2016, In : BMC Infectious Diseases. 16, 1, 7 p., 269.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
2018

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

Dorman, S. E., Schumacher, S. G., Alland, D., Nabeta, P., Armstrong, D. T., King, B., Hall, S. L., Chakravorty, S., Cirillo, D. M., Tukvadze, N., Bablishvili, N., Stevens, W., Scott, L., Rodrigues, C., Kazi, M. I., Joloba, M., Nakiyingi, L., Nicol, M. P., Ghebrekristos, Y., Anyango, I. & 12 others, Murithi, W., Dietze, R., Lyrio Peres, R., Skrahina, A., Auchynka, V., Chopra, K. K., Hanif, M., Liu, X., Yuan, X., Boehme, C. C., Ellner, J. J. & Denkinger, C. M., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Open Access
165 Citations (Scopus)
2020

Diagnostic accuracy of a novel tuberculosis point-of-care urine lipoarabinomannan assay for people living with HIV: A meta-analysis of individual in- and outpatient data

Broger, T., Nicol, M. P., Székely, R., Bjerrum, S., Sossen, B., Schutz, C., Opintan, J. A., Johansen, I. S., Mitarai, S., Chikamatsu, K., Kerkhoff, A. D., Macé, A., Ongarello, S., Meintjes, G., Denkinger, C. M. & Schumacher, S. G., May 2020, In : PLoS Medicine. 17, 5, p. e1003113

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2019

What causes symptoms suggestive of tuberculosis in HIV-positive people with negative initial investigations?

Hanifa, Y., Toro Silva, S., Karstaedt, A., Sahid, F., Charalambous, S., Chihota, V. N., Churchyard, G. J., von Gottberg, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Stevens, W., Fielding, K. L. & Grant, A. D., 1 Feb 2019, In : International Journal of Tuberculosis & Lung Disease. 23, 2, p. 157-165 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Prevalence and antibiotic susceptibility patterns of enteric bacterial pathogens in human and non-human sources in an urban informal settlement in Cape Town, South Africa

Kalule, J. B., Smith, A. M., Vulindhlu, M., Tau, N. P., Nicol, M. P., Keddy, K. H. & Robberts, L., 6 Nov 2019, In : BMC Microbiology. 19, 1, 244.

Research output: Contribution to journalArticle

Open Access
2020

Prevention of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 4)

Zar, H. J., Moore, D. P., Andronikou, S., Argent, A. C., Avenant, T., Cohen, C., Green, R. J., Itzikowitz, G., Jeena, P., Nicol, M. P., Pillay, A., Reubenson, G., Masekela, R. & Madhi, S. A., Aug 2020, In : South African Medical Journal. 110, 8, p. 741-746 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Longitudinal characterization of nasopharyngeal colonization with Streptococcus pneumoniae in a South African birth cohort post 13-valent pneumococcal conjugate vaccine implementation

Dube, F. S., Ramjith, J., Gardner-Lubbe, S., Nduru, P., Robberts, F. J. L., Wolter, N., Zar, H. J. & Nicol, M. P., 1 Dec 2018, In : Scientific Reports. 8, 1, 12497.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
2020

First clinical assessment of a prototype assay to detect the enzymatic activity of β-lactamase as a marker for pulmonary tuberculosis

Nabeta, P., Seshadri, P., Havumaki, J., Mbhele, S., Hendricks, L., Perkins, M. D., Nicol, M. P. & Denkinger, C. M., 19 Feb 2020, In : Diagnostic Microbiology and Infectious Disease. 115026.

Research output: Contribution to journalArticle

Open Access
2019

Brief Report: Real-World Performance and Interobserver Agreement of Urine Lipoarabinomannan in Diagnosing HIV-Associated Tuberculosis in an Emergency Center

Van Hoving, D. J., Lahri, S., Lategan, H. J., Nicol, M. P., Maartens, G. & Meintjes, G., 1 May 2019, In : Journal of acquired immune deficiency syndromes (1999). 81, 1, p. e10-e14

Research output: Contribution to journalArticle

2 Citations (Scopus)
2020

Drug-resistant tuberculosis patient care journeys in South Africa: a pilot study using routine laboratory data

Hill, J., Dickson-Hall, L., Grant, A. D., Grundy, C., Black, J., Kielmann, K., Mlisana, K., Mitrani, L., Loveday, M., Moshabela, M., Le Roux, S., Jassat, W., Nicol, M. & Cox, H., 1 Jan 2020, In : International Journal of Tuberculosis & Lung Disease. 24, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Open Access
2018

Lymphadenopathy in a TB-Endemic Region: Employing Focused Techniques in a Rapid Access Lymph Node Biopsy Clinic

Antel, K. R., Verburgh, E., Louw, V. J., Oosthuizen, J., Malherbe, F., Gary, M. & Nicol, M., 29 Nov 2018, In : Blood. 132, 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2019

Recent developments in the diagnosis of drug-resistant tuberculosis

Nicol, M. P. & Cox, H., 1 Jan 2019, In : Microbiology Australia. 40, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

2020

Differential RD-1-specific IFN-γ host responses to diverse Mycobacterium tuberculosis strains in HIV-uninfected persons may be explained by genotypic variation in the ESX-1 region

Tomasicchio, M., Limberis, J., van der Merwe, R., Jacobson, R., Meldau, R., Theron, G., Nicol, M., Warren, R. & Dheda, K., 1 Jul 2020, In : International Journal of Infectious Diseases. 96, p. 240-243

Research output: Contribution to journalArticle

Open Access
2019

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Schutz, C., Barr, D., Andrade, B. B., Shey, M., Ward, A., Janssen, S., Burton, R., Wilkinson, K. A., Sossen, B., Fukutani, K. F., Nicol, M., Maartens, G., Wilkinson, R. J. & Meintjes, G., Jul 2019, In : PLoS Medicine. 16, 7, p. e1002840

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)
2016

Respiratory microbes present in the nasopharynx of children hospitalised with suspected pulmonary tuberculosis in Cape Town, South Africa

Dube, F. S., Kaba, M., Robberts, F. J. L., Tow, L. A., Lubbe, S., Zar, H. J. & Nicol, M. P., 24 Oct 2016, In : BMC Infectious Diseases. 16, 1, 12 p., 597.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2018

Treatment of bronchiectasis exacerbations in children: which antibiotic?

Zar, H. J. & Nicol, M. P., 6 Oct 2018, In : The Lancet. 392, 10154, p. 1169-1170 2 p.

Research output: Contribution to journalComment/debate

Human breast milk bacteriome in health and disease

Ojo-Okunola, A., Nicol, M. & du Toit, E., 3 Nov 2018, In : Nutrients. 10, 11, 1643.

Research output: Contribution to journalReview article

Open Access
14 Citations (Scopus)

Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes

Breen, M. S., Wingo, A. P., Koen, N., Donald, K. A., Nicol, M., Zar, H. J., Ressler, K. J., Buxbaum, J. D. & Stein, D. J., 1 Oct 2018, In : Brain, Behavior, and Immunity. 73, p. 320-330 11 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2016

Incidence and diagnosis of pertussis in South African children hospitalized with lower respiratory tract infection

Muloiwa, R., Dube, F. S., Nicol, M. P., Zar, H. J. & Hussey, G. D., 10 Mar 2016, In : Pediatric Infectious Disease Journal. 35, 6, p. 611-616 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Distinct patterns in human milk microbiota and fatty acid profiles across specific geographic locations

Kumar, H., du Toit, E., Kulkarni, A., Aakko, J., Linderborg, K. M., Zhang, Y., Nicol, M. P., Isolauri, E., Yang, B., Collado, M. C. & Salminen, S., 13 Oct 2016, In : Frontiers in Microbiology. 7, OCT, 1619.

Research output: Contribution to journalArticle

Open Access
84 Citations (Scopus)

Analytical and clinical evaluation of the epistem genedrive assay for detection of mycobacterium tuberculosis

Shenai, S., Armstrong, D. T., Valli, E., Dolinger, D. L., Nakiyingi, L., Dietze, R., Dalcolmo, M. P., Nicol, M. P., Zemanay, W., Manabe, Y., Hadad, D. J., Marques-Rodrigues, P., Palaci, M., Peres, R. L., Gaeddert, M., Armakovitch, S., Nonyane, B. A. S., Denkinger, C. M., Banada, P., Joloba, M. L. & 4 others, Ellner, J., Boehme, C., Alland, D. & Dorman, S. E., 1 Apr 2016, In : Journal of Clinical Microbiology. 54, 4, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

How should tuberculosis molecular diagnostics be adapted for use in seriously ill HIV patients?

Nicol, M. P., 1 Dec 2016, In : EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 16, 12, p. 1237-1239 3 p.

Research output: Contribution to journalEditorial

2019

Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations

Ochodo, E. A., Kalema, N., Schumacher, S., Steingart, K., Young, T., Mallett, S., Deeks, J., Cobelens, F., Bossuyt, P. M., Nicol, M. P. & Cattamanchi, A., 2019, In : Wellcome Open Research. 4, p. 173

Research output: Contribution to journalReview article

Open Access
2016

Current knowledge and future research directions on fecal bacterial patterns and their association with asthma

Claassen-Weitz, S., Wiysonge, C. S., Machingaidze, S., Thabane, L., Horsnell, W. G. C., Zar, H. J., Nicol, M. P. & Kaba, M., 1 Jan 2016, In : Frontiers in Microbiology. 7, JUN, 838.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)
2018

Tuberculosis eradication: renewed commitment and global investment required

Cox, H. & Nicol, M. P., 1 Mar 2018, In : The Lancet Infectious Diseases. 18, 3, p. 228-229 2 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Characterisation of STEC and other diarrheic E. coli isolated on CHROMagar™STEC at a tertiary referral hospital, Cape Town

Kalule, J. B., Keddy, K. H. & Nicol, M. P., 8 Jun 2018, In : BMC Microbiology. 18, 1, 55.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2020

"A very humiliating illness": a qualitative study of patient-centered Care for Rifampicin-Resistant Tuberculosis in South Africa

Furin, J., Loveday, M., Hlangu, S., Dickson-Hall, L., le Roux, S., Nicol, M. & Cox, H., 17 Jan 2020, In : BMC Public Health. 20, 1, 76.

Research output: Contribution to journalArticle

Open Access

'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa

Sossen, B., Broger, T., Kerkhoff, A. D., Schutz, C., Trollip, A., Moreau, E., Schumacher, S. G., Burton, R., Ward, A., Wilkinson, R. J., Barr, D. A., Nicol, M. P., Denkinger, C. M. & Meintjes, G., 9 Jan 2020, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Research output: Contribution to journalReview article

Open Access

Correction to: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 2 Mar 2020, In : BMC Infectious Diseases. 20, 1, p. 187

Research output: Contribution to journalLetter

Open Access
2019

Longitudinal Population Dynamics of Staphylococcus aureus in the Nasopharynx During the First Year of Life

Abdulgader, S. M., Robberts, L., Ramjith, J., Nduru, P. M., Dube, F., Gardner-Lubbe, S., Zar, H. J. & Nicol, M. P., 15 Mar 2019, In : Frontiers in Genetics. 10, 10 p., 198.

Research output: Contribution to journalArticle

Open Access
2018

Proteomic comparison of three clinical diarrhoeagenic drug-resistant Escherichia coli isolates grown on CHROMagar™STEC media

Kalule, J. B., Fortuin, S., Calder, B., Robberts, L., Keddy, K. H., Nel, A. J. M., Garnett, S., Nicol, M., Warner, D. F., Soares, N. C. & Blackburn, J. M., 30 May 2018, In : Journal of Proteomics. 180, p. 25-35 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Human brucellosis in South Africa: Public health and diagnostic pitfalls

Wojno, J. M., Moodley, C., Pienaar, J., Beylis, N., Jacobsz, L., Nicol, M. P., Rossouw, J. & Bamford, C., 1 Jan 2016, In : South African Medical Journal. 106, 9, p. 883-885 3 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Diagnostic Test Accuracy in Childhood Pulmonary Tuberculosis: A Bayesian Latent Class Analysis

Schumacher, S. G., Van Smeden, M., Dendukuri, N., Joseph, L., Nicol, M. P., Pai, M. & Zar, H. J., 1 Nov 2016, In : American Journal of Epidemiology. 184, 9, p. 690-700 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Tuberculosis diagnostics: State of the art and future directions

Pai, M., Nicol, M. P. & Boehme, C. C., 1 Jan 2016, In : Microbiology Spectrum. 4, 5, TBTB2-0019-2016.

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)
2018

Preventing tuberculosis-related death in children with HIV

Tootla, H. D. & Nicol, M. P., 1 Feb 2018, In : The lancet. HIV. 5, 2, p. e62-e64

Research output: Contribution to journalComment/debate

2019

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients

Schutz, C., Ward, A., Burton, R., Nicol, M. P., Blumenthal, U., Meintjes, G. & Kerkhoff, A. D., 28 Aug 2019, In : Southern African Journal of HIV Medicine. 20, 1, 10 p., 978.

Research output: Contribution to journalArticle

Open Access