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  • Seyhan Yazar
2019

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

Williams, K., Hysi, P. G., Sensaki, S., Tideman, W., Yazar, S., Wedenoja, J., He, M., Parssinen, O., Mackey, D. A., Klaver, C. C. W., Hammond, C. J. & Saw, S-M., Jul 2019, In : Investigative ophthalmology & visual science. 60, 9, 3 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Open Access

Greater ocular sun exposure, measured objectively, is associated with increased risk of future pterygium in young adults

Lingham, G., Mackey, D., McKnight, C., Coroneo, M., Lucas, R. & Yazar, S., Nov 2019, In : Clinical and Experimental Ophthalmology. 47, p. 35-35 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2020
2019
2 Citations (Scopus)

How does spending time outdoors protect against myopia? A review

Lingham, G., MacKey, D. A., Lucas, R. & Yazar, S., 13 Nov 2019, In : British Journal of Ophthalmology.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Estimation of heritability and familial correlation in myopia is not affected by past sun exposure

Charng, J., Sanfilippo, P., Lingham, G., Stevenson, L., Mackey, D. & Yazar, S., 6 Dec 2019, In : Ophthalmic Genetics. 40, 6, p. 500-506 7 p.

Research output: Contribution to journalArticle

2020
2019

Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate

Lucas, R. M., Yazar, S., Young, A. R., Norval, M., de Gruijl, F. R., Takizawa, Y., Rhodes, L. E., Sinclair, C. A. & Neale, R. E., 1 Mar 2019, In : PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES. 18, 3, p. 641-680 40 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2020

Choroidal Thickness in Young Adults and its Association with Visual Acuity

Lee, S. S. Y., Lingham, G., Alonso-Caneiro, D., Chen, F. K., Yazar, S., Hewitt, A. W. & Mackey, D. A., Jun 2020, In : American Journal of Ophthalmology. 214, p. 40-51 12 p.

Research output: Contribution to journalArticle

2016
Open Access
File
9 Citations (Scopus)
267 Downloads (Pure)
2019

Ozone depletion, ultraviolet radiation, climate change and prospects for a sustainable future

Barnes, P. W., Williamson, C. E., Lucas, R. M., Robinson, S. A., Madronich, S., Paul, N. D., Bornman, J. F., Bais, A. F., Sulzberger, B., Wilson, S. R., Andrady, A. L., McKenzie, R. L., Neale, P. J., Austin, A. T., Bernhard, G. H., Solomon, K. R., Neale, R. E., Young, P. J., Norval, M., Rhodes, L. E. & 19 others, Hylander, S., Rose, K. C., Longstreth, J., Aucamp, P. J., Ballaré, C. L., Cory, R. M., Flint, S. D., de Gruijl, F. R., Häder, D. P., Heikkilä, A. M., Jansen, M. A. K., Pandey, K. K., Robson, T. M., Sinclair, C. A., Wängberg, S. Å., Worrest, R. C., Yazar, S., Young, A. R. & Zepp, R. G., 1 Jul 2019, In : Nature Sustainability. 2, 7, p. 569-579 11 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)
2020

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Consortium for Refractive Error and Myopia (CREAM) & UK Biobank Eye and Vision Consortium, 1 Dec 2020, In : Communications Biology. 3, 1, 133.

Research output: Contribution to journalArticle

Open Access
2018

Mitochondrial DNA variation and disease susceptibility in primary open-angle glaucoma

Singh, L. N., Crowston, J. G., Lopez Sanchez, M. I. G., Van Bergen, N. J., Kearns, L. S., Hewitt, A. W., Yazar, S., Mackey, D. A., Wallace, D. C. & Trounce, I. A., 1 Sep 2018, In : Investigative Ophthalmology and Visual Science. 59, 11, p. 4598-4602 5 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Genome-wide association study identifies a susceptibility locus for comitant esotropia and suggests a parent-of-origin effect

Strabismus Genetics Research Consortium, 1 Aug 2018, In : Investigative Ophthalmology and Visual Science. 59, 10, p. 4054-4064 11 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

Hysi, P. G., Valdes, A. M., Liu, F., Furlotte, N. A., Evans, D. M., Bataille, V., Visconti, A., Hemani, G., McMahon, G., Ring, S. M., Smith, G. D., Duffy, D. L., Zhu, G., Gordon, S. D., Medland, S. E., Lin, B. D., Willemsen, G., Jan Hottenga, J., Vuckovic, D., Girotto, G. & 24 others, Gandin, I., Sala, C., Concas, M. P., Brumat, M., Gasparini, P., Toniolo, D., Cocca, M., Robino, A., Yazar, S., Hewitt, A. W., Chen, Y., Zeng, C., Uitterlinden, A. G., Ikram, M. A., Hamer, M. A., Van Duijn, C. M., Nijsten, T., MacKey, D. A., Falchi, M., Boomsma, D. I., Martin, N. G., Hinds, D. A., Kayser, M. & Spector, T. D., 1 May 2018, In : Nature Genetics. 50, 5, p. 652-656 5 p.

Research output: Contribution to journalArticle

Open Access
30 Citations (Scopus)
2020
2018

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

CREAM, 23andMe Research Team & UK Biobank Eye and Vision Consortium, 1 Jun 2018, In : Nature Genetics. 50, 6, p. 834-848 15 p.

Research output: Contribution to journalArticle

Open Access
63 Citations (Scopus)

LOW VITAMIN D LEVELS ARE NOT ASSOCIATED WITH REFRACTIVE ERROR IN MIDDLE-AGED AND OLDER WESTERN AUSTRALIAN ADULTS

Lingham, G., Yazar, S., Lucas, R. M., Walsh, J. P., Zhu, K., Hunter, M., Lim, E. M., Cooke, B. R. & Mackey, D. A., Nov 2018, In : Clinical and Experimental Ophthalmology. 46, p. 31-32 2 p., S1003.

Research output: Contribution to journalAbstract/Meeting Abstract

2020

How many young drivers do not meet the driver licencing vision requirements?

Tu, M. Y., Yazar, S., Mackey, D. A. & Lee, S. S. Y., Aug 2020, In : Clinical and Experimental Ophthalmology. 48, 6, p. 853-854 2 p.

Research output: Contribution to journalLetter

File
52 Downloads (Pure)

Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism

Charng, J., Simcoe, M., Sanfilippo, P. G., Allingham, R. R., Hewitt, A. W., Hammond, C. J., Mackey, D. A. & Yazar, S., 1 Dec 2020, In : Scientific Reports. 10, 1, 12485.

Research output: Contribution to journalArticle

Open Access
2016

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

Fan, Q., Guo, X., Tideman, J. W. L., Williams, K. M., Yazar, S., Hosseini, S. M., Howe, L. D., St Pourcain, B., Evans, D. M., Timpson, N. J., Mcmahon, G., Hysi, P. G., Krapohl, E., Wang, Y. X., Jonas, J. B., Baird, P. N., Wang, J. J., Cheng, C., Teo, Y., Wong, T. & 16 others, Ding, X., Wojciechowski, R., Young, T. L., Parssinen, O., Oexle, K., Pfeiffer, N., Bailey-Wilson, J. E., Paterson, A. D., Klaver, C. C. W., Plomin, R., Hammond, C. J., Mackey, D., He, M., Saw, S., Williams, C. & Guggenheim, J. A., 13 May 2016, In : Scientific Reports. 6, 25853.

Research output: Contribution to journalArticle

Open Access
39 Citations (Scopus)
Open Access
File
6 Citations (Scopus)
229 Downloads (Pure)
2019

Differential stability of variant OPN1LW gene transcripts in myopic patients

Mountford, J. K., Davies, W. I. L., Griffiths, L. R., Yazar, S., Mackey, D. A. & Hunt, D. M., 1 Jan 2019, In : Molecular Vision. 25, p. 183-193 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
327 Downloads (Pure)
2018

An update of the prevalence of myopia in an older Australian population

Mackey, D., Lingham, G., Lee, S., Hunter, M., Wood, D., Hewitt, A. W., Mitchell, P., Taylor, H. R. & Yazar, S., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p., 3954.

Research output: Contribution to journalAbstract/Meeting Abstract

2019

The relationship between optic disc parameters and female reproductive factors in young women

Lee, S. S. Y., Yazar, S., Pasquale, L. R., Sanfilippo, P. G., Hewitt, A. W., Hickey, M., Skinner, R. & Mackey, D. A., May 2019, In : Asia-Pacific Journal of Ophthalmology. 8, 3, p. 224-228 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (vol 9, 4774, 2018)

Melanoma GWAS Consortium, 14 Jan 2019, In : Nature Communications. 10, 3 p., 299.

Research output: Contribution to journalComment/debate

Open Access
2020

Rationale and protocol for the 7- And 8-year longitudinal assessments of eye health in a cohort of young adults in the Raine Study

Lee, S. S. Y., Lingham, G., Yazar, S., Sanfilippo, P. G., Charng, J., Chen, F. K., Hewitt, A. W., Ng, F., Hammond, C., Straker, L. M., Eastwood, P. R., MacGregor, S., Rose, K. A., Lucas, R. M., Guggenheim, J. A., Saw, S. M., Coroneo, M. T., He, M. & MacKey, D. A., 25 Mar 2020, In : BMJ Open. 10, 3, e033440.

Research output: Contribution to journalArticle

Open Access
2018

Investigating the long-term impact of a childhood sun-exposure intervention, with a focus on eye health: protocol for the Kidskin-Young Adult Myopia Study

Lingham, G., Milne, E., Cross, D., English, D. R., Johnston, R. S., Lucas, R. M., Yazar, S. & Mackey, D. A., 31 Jan 2018, In : BMJ Open. 8, 1, p. e020868

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Environmental effects of ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2017

Bais, A. F., Lucas, R. M., Bornman, J. F., Williamson, C. E., Sulzberger, B., Austin, A. T., Wilson, S. R., Andrady, A. L., Bernhard, G., McKenzie, R. L., Aucamp, P. J., Madronich, S., Neale, R. E., Yazar, S., Young, A. R., De Gruijl, F. R., Norval, M., Takizawa, Y., Barnes, P. W., Robson, T. M. & 18 others, Robinson, S. A., Ballaré, C. L., Flint, S. D., Neale, P. J., Hylander, S., Rose, K. C., Wängberg, S., Häder, D. P., Worrest, R. C., Zepp, R. G., Paul, N. D., Cory, R. M., Solomon, K. R., Longstreth, J., Pandey, K. K., Redhwi, H. H., Torikai, A. & Heikkilä, A. M., 1 Jan 2018, In : Photochemical and Photobiological Sciences. 17, 2, p. 127-179 53 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
2019

Repurposing blue laser autofluorescence to measure ocular sun exposure

Lingham, G., Burton, A., Brown, H. A., Huynh, E., Yazar, S., Coroneo, M. T. & Mackey, D. A., May 2019, In : Clinical and Experimental Ophthalmology. p. 445-452 8 p.

Research output: Contribution to journalArticle

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (vol 9, 1864, 2018)

Blue Mountains Eye Study-GWAS Grp, NEIGHBORHOOD Consortium & Wellcome Trust Case Control, 8 Jan 2019, In : Nature Communications. 10, 3 p., 155.

Research output: Contribution to journalArticle

Open Access

IMI - Myopia Genetics Report

CREAM Consortium, Feb 2019, In : Investigative ophthalmology & visual science. 60, 3, p. M89-M105 17 p.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)
2018

The relationship between female reproductive factors and optic disc parameters in young female adults

Lee, S., Yazar, S., Pasquale, L. R., Sanfilippo, P., Hewitt, A. W., Hickey, M., Skinner, R. & Mackey, D., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2016

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

Fan, Q., Verhoeven, V. J. M. J. M., Wojciechowski, R., Barathi, V. A. A., Hysi, P. G. G., Guggenheim, J. A. A., Hohn, R., Vitart, V., Khawaja, A. P. P., Yamashiro, K., Hosseini, S. M. M., Lehtimaki, T., Lu, Y., Haller, T., Xie, J., Delcourt, C., Pirastu, M., Wedenoja, J., Gharahkhani, P., Venturini, C. & 134 others, Miyake, M., Hewitt, A. W. W., Guo, X., Mazur, J., Huffman, J. E. E., Williams, K. M. M., Polasek, O., Campbell, H., Rudan, I., Vatavuk, Z., Wilson, J. F. F., Joshi, P. K. K., McMahon, G., St Pourcain, B., Evans, D. M. M., Simpson, C. L. L., Schwantes-An, T-H. -H., Igo, R. P. P., Mirshahi, A., Cougnard-Gregoire, A., Bellenguez, C., Blettner, M., Raitakari, O., Kahonen, M., Seppala, I., Zeller, T., Meitinger, T., Ried, J. S. S., Gieger, C., Portas, L., Van Leeuwen, E. M. M., Amin, N., Uitterlinden, A. G. G., Rivadeneira, F., Hofman, A., Vingerling, J. R. R., Wang, Y. X. X., Wang, X., Tai-Hui Boh, E., Ikram, M. K. K., Sabanayagam, C., Gupta, P., Tan, V., Zhou, L., Ho, C. E. H. E. H., Lim, W., Beuerman, R. W. W., Siantar, R., Tai, E-S. -S., Vithana, E., Mihailov, E., Khor, C-C. -C., Hayward, C., Luben, R. N. N., Foster, P. J. J., Klein, B. E. K. E. K., Klein, R., Wong, H-S. -S., Mitchell, P., Metspalu, A., Aung, T., Young, T. L. L., He, M., Parssinen, O., Van Duijn, C. M. M., Jin Wang, J., Williams, C., Jonas, J. B. B., Teo, Y-Y. -Y., MacKey, D. A., Oexle, K., Yoshimura, N., Paterson, A. D. D., Pfeiffer, N., Wong, T-Y. -Y., Baird, P. N. N., Stambolian, D., Wilson, J. E. B. E. B., Cheng, C-Y. -Y., Hammond, C. J. J., Klaver, C. C. W. C. W., Saw, S-M. -M., Rahi, J. S. S., Korobelnik, J-F. -F., Kemp, J. P. P., Timpson, N. J. J., Smith, G. D. D., Craig, J. E. E., Burdon, K. P. P., Fogarty, R. D. D., Iyengar, S. K. K., Chew, E., Janmahasatian, S., Martin, N. G. G., MacGregor, S., Xu, L., Schache, M., Nangia, V., Panda-Jonas, S., Wright, A. F. F., Fondran, J. R. R., Lass, J. H. H., Feng, S., Zhao, J. H. H., Khaw, K-T. -T., Wareham, N. J. J., Rantanen, T., Kaprio, J., Pang, C. P. P., Chen, L. J. J., Tam, P. O. O., Jhanji, V., Young, A. L. L., Doring, A., Raffel, L. J. J., Cotch, M-F. -F., Li, X., Yip, S. P. P., Yap, M. K. H. K. H., Biino, G., Vaccargiu, S., Fossarello, M., Fleck, B., Yazar, S., Tideman, J. W. L. W. L., Tedja, M., Deangelis, M. M. M., Morrison, M., Farrer, L., Zhou, X., Chen, W., Mizuki, N., Meguro, A. & Makela, K. M. M., 2016, In : Nature Communications. 7

Research output: Contribution to journalArticle

Open Access
52 Citations (Scopus)
2018

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Melanoma GWAS Consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 4774.

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)
2020

Re-engaging an inactive cohort of young adults: Evaluating recruitment for the Kidskin Young Adult Myopia Study

Lingham, G., Mackey, D. A., Seed, N., Ryan, L., Milne, E., Lucas, R. M., Franchina, M., Lee, S. S. Y. & Yazar, S., 24 May 2020, In : BMC Medical Research Methodology. 20, 1, 127.

Research output: Contribution to journalArticle

Open Access
2018

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Iglesias, A. I., Mishra, A., Vitart, V., Bykhovskaya, Y., Höhn, R., Springelkamp, H., Cuellar-Partida, G., Gharahkhani, P., Bailey, J. N. C., Willoughby, C. E., Li, X., Yazar, S., Nag, A., Khawaja, A. P., Polašek, O., Siscovick, D., Mitchell, P., Tham, Y. C., Haines, J. L., Kearns, L. S. & 124 others, Hayward, C., Shi, Y., Van Leeuwen, E. M., Taylor, K. D., Wang, J. J., Rochtchina, E., Attia, J., Scott, R., Holliday, E. G., Baird, P. N., Xie, J., Inouye, M., Viswanathan, A., Sim, X., Bonnemaijer, P., Rotter, J. I., Martin, N. G., Zeller, T., Mills, R. A., Staffieri, S. E., Jonas, J. B., Schmidtmann, I., Boutin, T., Kang, J. H., Lucas, S. E. M., Wong, T. Y., Beutel, M. E., Wilson, J. F., Allingham, R. R., Brilliant, M. H., Budenz, D. L., Christen, W. G., Fingert, J., Friedman, D. S., Gaasterland, D., Gaasterland, T., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Loomis, S. J., Moroi, S. E., Pericak-Vance, M. A., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Zhang, K., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Uitterlinden, A. G., Vithana, E. N., Foster, P. J., Hysi, P. G., Hewitt, A. W., Khor, C. C., Pasquale, L. R., Montgomery, G. W., Klaver, C. C. W., Aung, T., Pfeiffer, N., MacKey, D. A., Hammond, C. J., Cheng, C. Y., Craig, J. E., Rabinowitz, Y. S., Wiggs, J. L., Burdon, K. P., Van Duijn, C. M. & MacGregor, S., 1 Dec 2018, In : Nature Communications. 9, 1, 1864.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)
2019

Vitamin D and its pathway genes in myopia: Systematic review and meta-analysis

Tang, S. M., Lau, T., Rong, S. S., Yazar, S., Chen, L. J., Mackey, D. A., Lucas, R. M., Pang, C. P. & Yam, J. C., 1 Jan 2019, In : British Journal of Ophthalmology. 103, 1, p. 8-17

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
359 Downloads (Pure)
2016

When do myopia genes have their effect? Comparison of genetic risks between children and adults

Tideman, J. W. L., Fan, Q., Polling, J. R., Guo, X., Yazar, S., Khawaja, A., Höhn, R., Lu, Y., Jaddoe, V. W. V., Yamashiro, K., Yoshikawa, M., Gerhold-Ay, A., Nickels, S., Zeller, T., He, M., Boutin, T., Bencic, G., Vitart, V., Mackey, D., Foster, P. J. & 5 others, Macgregor, S., Williams, C., Saw, S. M., Guggenheim, J. A. & Klaver, C. C. W., 2016, In : Genetic Epidemiology. 40, 8, p. 756-66 689 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
4 Citations (Scopus)
2019
1 Citation (Scopus)
2016

Quantification of sun-related changes in the eye in conjunctival ultraviolet autofluorescence images

Huynh, E., Bukowska, D. M., Yazar, S., McKnight, C., Mian, A. & Mackey, D., Jul 2016, In : Journal of Medical Imaging. 3, 3, p. 1-7 7 p., 034001.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
227 Downloads (Pure)
2019

Pterygium: Prevalence and Associations in Western Australian Adults

Mackey, D. A., Stevenson, L., Lingham, G., Burton, A., Brown, H., Huynh, E., Tan, I., Sanfilippo, P. & Yazar, S., Jul 2019, In : Investigative ophthalmology & visual science. 60, 9, 3 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2016

Assessing the Genetic Predisposition of Education on Myopia: A Mendelian Randomization Study

Cuellar-Partida, G., Lu, Y., Kho, P. F., Hewitt, A. W., Wichmann, H. E., Yazar, S., Stambolian, D., Bailey-Wilson, J. E., Wojciechowski, R., Wang, J. J., Mitchell, P., Mackey, D. & Macgregor, S., 2016, In : Genetic Epidemiology. 40, 1, p. 66-72

Research output: Contribution to journalArticle

26 Citations (Scopus)
2018

Low serum 25-hydroxyvitamin D is not associated with myopic refractive error in Western Australian older adults

Lingham, G., Lucas, R. M., Yazar, S., Walsh, J. P., Zhu, K., Lim, E. M., Cooke, B., Hunter, M. & Mackey, D., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p., 3370.

Research output: Contribution to journalAbstract/Meeting Abstract

2019

Can young adults accurately recall their time spent outdoors during childhood?

Lingham, G., Milne, E., Lucas, R. M., Mackey, D. A. & Yazar, S., Jul 2019, In : Investigative ophthalmology & visual science. 60, 9, 3 p.

Research output: Contribution to journalAbstract/Meeting Abstract