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• 2016

  Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

  Walls, M. L., Hart, R., Keelan, J. A. & Ryan, J., 1 Nov 2016, In : Fertility and Sterility. 106, 6, p. 1392-1398.e5

  Research output: Contribution to journal › Article

  • Intracytoplasmic Sperm Injections
  • Fertilization
  • Oocytes
  • Polycystic Ovary Syndrome
  • Polar Bodies
  8 Citations (Scopus)

• T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

  Friedland, P., Lee-Pullen, T. F., Nathan, L. A., Watts, R., Keelan, J. A., Payne, M. S. & Ireland, D. J., 2016, In : Journal of Reproductive Immunology. 116, p. 93-97 5 p.

  Research output: Contribution to journal › Article

  • Ureaplasma
  • Cytokines
  • T-Lymphocytes
  • Pregnancy
  • Premature Birth
  1 Citation (Scopus)
• 2018

  Toll-like receptor-4: A new target for preterm labour pharmacotherapies?

  Robertson, S. A., Wahid, H. H., Chin, P. Y., Hutchinson, M. R., Moldenhauer, L. M. & Keelan, J. A., 2018, In : Current Pharmaceutical Design. 24, 9, p. 960-973

  Research output: Contribution to journal › Review article

  • Premature Obstetric Labor
  • Toll-Like Receptor 4
  • Premature Birth
  • Drug Therapy
  • Uterine Cervical Diseases
  9 Citations (Scopus)
• 2012

  Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

  Whitehouse, A., Mattes, E., Maybery, M., Dissanayake, C., Sawyer, M., Jones, R., Pennell, C., Keelan, J. & Hickey, M., 30 Oct 2012, In : Journal of Neurodevelopmental Disorders. 4, p. 25pp

  Research output: Contribution to journal › Article

  Open Access

  • Testosterone
  • Cohort Studies
  • Pregnancy
  • Fetal Blood
  • Population
  40 Citations (Scopus)
• 2017

  Progesterone to prevent preterm birth: the studies are getting better, but there is still room for improvement

  Chung, C. M., van Zijl, M., Keelan, J. A. & Mol, B. W. W., 1 Jun 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 7, p. 1016 1 p.

  Research output: Contribution to journal › Comment/debate
  2 Citations (Scopus)

• The influence of maternal phthalate exposure upon adult male reproductive function

  Hart, R., Frederiksen, H., Doherty, D. A., Keelan, J., Skakkebaek, N. E., Minaee, N., Handelsman, D., Newnham, J., Dickinson, J., Pennell, C., Norman, R. J. & Main, G. K., Sep 2017, In : Fertility and Sterility. 108, 3, p. E30-E30 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  1 Citation (Scopus)

• The impact of antenatal exposure to environmentally ubiquitous bisphenol A (BPA) on measures of male reproductive function at 20 years of age

  Hart, R., Doherty, D., Keelan, J., McLachlan, R., Dickinson, J., Newnham, J., Pennell, C., Norman, R. & Handelsman, D., Jul 2017, In : Human Reproduction. 32, p. 81-82 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  2 Citations (Scopus)
• 2018

  Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

  Ho, D., Kretzmann, J., Norret, M., Toshniwal, P., Veder, J. P., Jiang, H., Guagliardo, P., Munshi, A. M. A., Chawla, R., Evans, C., Clemons, T., Nguyen, M., Kretzmann, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Kilburn, M. & 3 others, Hurley, L., Smith, N. & Swaminatha Iyer, K., Dec 2018, In : Nature Nanotechnology. 13, 2

  Research output: Contribution to journal › Article

  • Nanorods
  • Gold
  • DNA
  • nanorods
  • deoxyribonucleic acid
  6 Citations (Scopus)
• 2017

  Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

  Jamnadass, E. S. L., Keelan, J. A., Russell-Smith, S. N., Hickey, M., Maybery, M. T. & Whitehouse, A. J. O., 1 Mar 2017, In : PLoS One. 12, 3, e0173493.

  Research output: Contribution to journal › Article

  Open Access

  • umbilical cord
  • Umbilical Cord
  • androgens
  • Androgens
  • estrogens

• Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus

  Guelfi, K., Ong, MJ., Li, S., Wallman, K., Doherty, D., Fournier, P., Newnham, J. & Keelan, J., Oct 2017, In : Metabolism. 75, p. 54-60

  Research output: Contribution to journal › Article

  Open Access

  File

  • Adipokines
  • Gestational Diabetes
  • Insulin Resistance
  • Mothers
  • Adiponectin
  17 Citations (Scopus)

  222 Downloads (Pure)
• 2019

  Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 Jan 2019, In : Letters in Applied Microbiology. 68, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Article

  • Biomass
  • Microbiota
  • Polymerase Chain Reaction
  • DNA
  • DNA Contamination
  22 Citations (Scopus)

• The Not-so-Sterile Womb: Evidence That the Human Fetus Is Exposed to Bacteria Prior to Birth

  Stinson, L. F., Boyce, M. C., Payne, M. S. & Keelan, J. A., 4 Jun 2019, In : Frontiers in Microbiology. 10, 15 p., 1124.

  Research output: Contribution to journal › Article

  Open Access
  54 Citations (Scopus)
• 2017

  Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

  Park, B. Y., Lee, B. K., Burstyn, I., Tabb, L. P., Keelan, J. A., Whitehouse, A. J. O., Croen, L. A., Fallin, M. D., Hertz-Picciotto, I., Montgomery, O. & Newschaffer, C. J., 31 Jan 2017, In : Molecular Autism. 8, 1, p. 1-12 12 p.

  Research output: Contribution to journal › Article

  Open Access

  • Autism Spectrum Disorder
  • Fetal Blood
  • Androgens
  • Cohort Studies
  • Phenotype
  10 Citations (Scopus)
• 2020

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, N. E., Juul, A., Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, K. M. & Frederiksen, H., 1 May 2020, In : Environmental Research. 184, 109231.

  Research output: Contribution to journal › Article

  • phthalic acid
  • phthalate
  • serum
  • woman
  • Pregnant Women
  2 Citations (Scopus)

• The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence

  Berman, Y. E., Doherty, D. A., Main, K. M., Frederiksen, H., Keelan, J. A., Newnham, J. P. & Hart, R. J., 16 Oct 2020, In : Environmental Research. 110313.

  Research output: Contribution to journal › Article

  • phthalic acid
  • adolescence
  • phthalate
  • Body Composition
  • Metabolites
• 2018

  The possible impact of antenatal exposure to ubiquitous phthalates upon male reproductive function at 20 years of age

  Hart, R. J., Frederiksen, H., Doherty, D. A., Keelan, J. A., Skakkebaek, N., Minaee, N., McLachlan, R., Newnham, J. P., Dickinson, J. E., Pennell, C. E., Norman, R. & Main, K., 4 Jun 2018, In : Frontiers in Endocrinology. 9, p. 1-11 288.

  Research output: Contribution to journal › Article

  Open Access

  File

  • phthalic acid
  • Serum
  • Testosterone
  • Semen
  • mono-(2-ethylhexyl)phthalate
  15 Citations (Scopus)

  128 Downloads (Pure)
• 2012

  Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

  Yang, H., Sun, C., Fan, Z., Tian, X., Yan, L., Du, L., Liu, Y., Chen, C., Liang, X., Anderson, GJ., Keelan, J., Zhao, Y. & Nie, G., 2012, In : Scientific Reports. 2, p. 847 - 854

  Research output: Contribution to journal › Article

  Open Access
  88 Citations (Scopus)
• 2016

  IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)
• 2012

  Ceramide biosynthesis and metabolism in trophoblast syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Molecular and Cellular Endocrinology. 362, p. 48 - 59

  Research output: Contribution to journal › Article
  11 Citations (Scopus)
• 2019

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L., Mathiesen, B., Assens, M., Krause, M., Skakkebaek, N. E., Juul, A., Andersson, A-M., Hart, R., Newnham, J., Keelan, J., Main, K., Pennell, C. & Frederiksen, H., Sep 2019, In : Hormone Research in Paediatrics. 91, p. 118-119 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  6 Citations (Scopus)
• 2013

  Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)

• Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

  Jones, M., Mark, P., Keelan, J., Barden, A., Mas, E., Mori, T. & Waddell, B., Aug 2013, In : Journal of Lipid Research. 54, p. 2247-2254

  Research output: Contribution to journal › Article

  Open Access
  40 Citations (Scopus)
• 2017

  The pregnant women as a drug orphan: a global survey of registered clinical trials of pharmacological interventions in pregnancy

  Scaffidi, J., Mol, B. W. & Keelan, J. A., 1 Jan 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 1, p. 132-140 9 p.

  Research output: Contribution to journal › Article

  • Orphan Drug Production
  • 1-phenyl-3,3-dimethyltriazene
  • Pregnant Women
  • Pharmacology
  • Clinical Trials
  28 Citations (Scopus)
• 2013

  Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

  Robinson, M., Whitehouse, A., Jacoby, P., Mattes, E., Sawyer, M. G., Keelan, J. & Hickey, M., 2013, In : PLoS One. 8, 4, p. 8pp

  Research output: Contribution to journal › Article

  Open Access

  File

  • Fetal Blood
  • Testosterone
  • Prospective Studies
  • Child Behavior
  • Checklist
  10 Citations (Scopus)

  11 Downloads (Pure)
• 2012

  Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood

  Whitehouse, A., Mattes, E., Maybery, M., Sawyer, M. G., Jacoby, P., Keelan, J. & Hickey, M., 2012, In : Journal of Child Psychology and Psychiatry and Allied Disciplines. 53, 7, p. 726–734

  Research output: Contribution to journal › Article
  54 Citations (Scopus)
• 2013

  The association between perinatal testosterone concentration and early vocabulary development: A prospective cohort study

  Hollier, L., Mattes, E., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Biological Psychology. 92, p. 212-215

  Research output: Contribution to journal › Article
  25 Citations (Scopus)
• 2019

  Prospective study of the association between in-utero exposures to circulating maternal phthalate metabolites and timing of menarche

  Hart, R., Nathan, E., Doherty, D., Frederiksen, H., Keelan, J., Skakkebaek, N., Hickey, M., Newnham, J. & Main, K., Jul 2019, In : Human Reproduction. 34, p. 398-399 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2017

  Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

  Ho, D., Leong, J. W., Crew, R. C., Norret, M., House, M. J., Mark, P., Waddell, B. J., Swaminatha Iyer, K. & Keelan, J. A., 6 Jun 2017, In : Scientific Reports. 7, 1, 2866 .

  Research output: Contribution to journal › Article

  Open Access

  • polyglycidyl methacrylate
  • Nanoparticles
  • Mothers
  • Pregnancy
  • Placenta
  14 Citations (Scopus)
• 2016

  Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

  Keelan, J. A. & Newnham, J. P., 2016, Swtitzerland: Frontiers Media SA. 101 p. (Frontiers in Immunology)

  Research output: Book/Report › Edited book/Anthology
• 2020

  Maternal perinatal depression, circulating oxytocin levels and childhood emotional disorders at 4 years of age: The importance of psychosocial context

  Galbally, M., Watson, S. J., Keelan, J., MacMillan, K. K., Power, J., IJzendoorn, M. V. & Lewis, A. J., Nov 2020, In : Journal of Psychiatric Research. 130, p. 247-253 7 p.

  Research output: Contribution to journal › Article

  • Oxytocin
  • Depression
  • Mothers
  • Pregnancy
  • Postpartum Period
• 2018

  A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2018, In : Frontiers of Medicine. 5, 135.

  Research output: Contribution to journal › Review article

  Open Access

  • Microbiota
  • Obesity
  • Dysbiosis
  • Noncommunicable Diseases
  • Maternal Age
  46 Citations (Scopus)

• Comparison of Meconium DNA extraction methods for use in microbiome studies

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 20 Feb 2018, In : Frontiers in Microbiology. 9, FEB, 270.

  Research output: Contribution to journal › Article

  Open Access

  • Meconium
  • Microbiota
  • DNA
  • Bacterial DNA
  • Polymerase Chain Reaction
  16 Citations (Scopus)
• 2019

  Re: "amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community" (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

  Payne, M. S., Keelan, J. A. & Stinson, L. F., 12 Feb 2019, In : Microbiome. 7, 1, 3 p., 20.

  Research output: Contribution to journal › Article

  Open Access

  • Amniotic Fluid
  • Microbiota
  • Pregnancy
  3 Citations (Scopus)

• Profiling bacterial communities in low biomass samples: Pitfalls and considerations

  Stinson, L. F., Keelan, J. A. & Payne, M. S., Nov 2019, In : Microbiology Australia. 40, 4, p. 181-185 5 p.

  Research output: Contribution to journal › Review article

  • Biomass
  • Workflow
  • rRNA Genes
  • Built Environment
  • Meconium
  3 Citations (Scopus)
• 2017

  Interaction of gold nanorods with genomic DNA

  Kretzmann, J., Ho, D., Toshniwal, P., Evans, C., Norret, M., Nguyen, M., Veder, J-P., Jiang, H., Munshi, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Hurley, L., Kilburn, M., Smith, N. & Iyer, K. S., 20 Aug 2017, In : ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 254, 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2016

  Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2016, In : Critical Reviews in Microbiology. 43, 3, p. 352-369 18 p.

  Research output: Contribution to journal › Review article

  • Seeds
  • Microbiota
  • Gastrointestinal Microbiome
  • Health
  • Extraembryonic Membranes
  60 Citations (Scopus)
• 2018

  Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

  Keelan, J. A., Feb 2018, In : Journal of Reproductive Immunology. 125, p. 89-99 11 p.

  Research output: Contribution to journal › Review article
  43 Citations (Scopus)
• 2019

  Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

  Stinson, L., Payne, M. & Keelan, J., Sep 2019, In : Placenta. 85, p. 12-23

  Research output: Contribution to journal › Article

  • Parturition
  • cyclic guanosine monophosphate-adenosine monophosphate
  • Inflammation
  • Poly I-C
  • resiquimod
  3 Citations (Scopus)
• 2016

  Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

  Payne, M., Ireland, D., Watts, R., Nathan, L., Furfaro, L., Kemp, M., Keelan, J. & Newnham, J., 18 Oct 2016, In : BMC Pregnancy and Childbirth. 16, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Premature Birth
  • Candida albicans
  • Pregnant Women
  • Genotype
  22 Citations (Scopus)

• A new, potent, and placenta-permeable macrolide antibiotic, solithromycin, for the prevention and treatment of bacterial infections in pregnancy

  Keelan, J., Payne, M., Kemp, M., Ireland, D. & Newnham, J., 1 Apr 2016, In : Frontiers in Immunology. 7, p. 1-11 11 p., 111.

  Research output: Contribution to journal › Review article

  Open Access

  • solithromycin
  • Macrolides
  • Bacterial Infections
  • Placenta
  • Anti-Bacterial Agents
  15 Citations (Scopus)
• 2019

  Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 May 2019, In : Letters in Applied Microbiology. 68, 5, p. 378-385 8 p.

  Research output: Contribution to journal › Article

  • propidium monoazide
  • Meconium
  • Bacterial DNA
  • Microbiota
  • Cell-Free Nucleic Acids
  8 Citations (Scopus)
• 2017

  Cord blood androgen measurements: the importance of assay validation

  Keelan, J. A., Hickey, M. & Hollier, L. P., Jun 2017, In : Human Reproduction. 32, 6, p. 1360-1360 1 p.

  Research output: Contribution to journal › Letter
• 2018

  Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study

  Hickey, M., Lawson, L. P., Marino, J. L., Keelan, J. A. & Hart, R., 1 Oct 2018, In : Fertility and Sterility. 110, 5, p. 965-973 9 p.

  Research output: Contribution to journal › Article

  • Sex Hormone-Binding Globulin
  • Menarche
  • Umbilical Cord
  • Steroids
  • Cohort Studies
  2 Citations (Scopus)
• 2017

  The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

  Lamont, R. F., Keelan, J. A., Larsson, P. G. & Jørgensen, J. S., 1 Feb 2017, In : Acta Obstetricia et Gynecologica Scandinavica. 96, 2, p. 139-143 5 p.

  Research output: Contribution to journal › Comment/debate

  • Bacterial Vaginosis
  • Clindamycin
  • Premature Birth
  • Gynecology
  • Obstetrics
  10 Citations (Scopus)
• 2012

  Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Reproductive Biomedicine Online. 24, p. 224-234

  Research output: Contribution to journal › Article
  12 Citations (Scopus)

• Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-kB

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2012, In : Molecular Human Reproduction. 18, 7, p. 341 - 353

  Research output: Contribution to journal › Article
  47 Citations (Scopus)
• 2016

  Editorial: Advances in the prevention and treatment of inflammation-associated preterm birth

  Keelan, J. A. & Newnham, J. P., 2016, In : Frontiers in Immunology. 7, JUN, p. 5-6 2 p.

  Research output: Contribution to journal › Letter

  Open Access
  4 Citations (Scopus)
• 2013

  The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone

  Mark, P., Lewis, J. L., Jones, M., Keelan, J. & Waddell, B., Jul 2013, In : Placenta. 34, 7, p. 559-566

  Research output: Contribution to journal › Article

  • Inner Ear
  • Placenta
  • Dexamethasone
  • Glucocorticoids
  • Pregnancy
  17 Citations (Scopus)
• 2018

  Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

  Beaudry-Richard, A., Nadeau-Vallée, M., Prairie, É., Maurice, N., Heckel, É., Nezhady, M., Pundir, S., Madaan, A., Boudreault, A., Hou, X., Quiniou, C., Sierra, E. M., Beaulac, A., Lodygensky, G., Robertson, S. A., Keelan, J., Adams-Waldorf, K., Olson, D. M., Rivera, J. C., Lubell, W. D. & 3 others, Joyal, J. S., Bouchard, J. F. & Chemtob, S., 8 Aug 2018, In : Scientific Reports. 8, 1, 11875.

  Research output: Contribution to journal › Article

  Open Access

  • Interleukin-1
  • Inflammation
  • Chorioamnionitis
  • Hyperoxia
  • Retinal Vessels
  9 Citations (Scopus)
• 2017

  Recent advances in the prevention of preterm birth

  Keelan, J. & Newnham, J., 2017, In : F1000Research. 6, 6(F1000 Faculty Rev):1139

  Research output: Contribution to journal › Review article

  Open Access
  14 Citations (Scopus)