Find Research outputs — the UWA Profiles and Research Repository

2011

Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

Research output: Contribution to journal › Article

15 Citations (Scopus)

2014

Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

Keelan, J. & Pugazhenthi, K., 2014, In : Placenta. Accepted 15 September 201, p. 1043-1048

Research output: Contribution to journal › Article

10 Citations (Scopus)

2015

Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy

Keelan, J., Leong, J. W., Ho, D. & Iyer, K., 2015, In : Nanomedicine. 10, 14, p. 2229-2247

Research output: Contribution to journal › Article

43 Citations (Scopus)

2014

Role of Wnt signalling in early pregnancy

Nayeem, S., Arfuso, F., Dharmarajan, A. & Keelan, J., 2014, In : Reproduction, Fertility and Development. accepted 5 August 2014, published online 5 September 2014, p. doi: 10.1071/RD14079

Research output: Contribution to journal › Review article

12 Citations (Scopus)

Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

Hollier, L. P., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., Dec 2014, In : Biological Psychology. 103, 1, p. 48-53

Research output: Contribution to journal › Article

Open Access

File

11 Citations (Scopus)

478 Downloads (Pure)

2017

Reducing preterm birth by a state-wide multifaceted program: an implementation study

Newnham, J. P., White, S. W., Meharry, S., Lee, HS., Pedretti, M. K., Arrese, C. A., Keelan, J. A., Kemp, M. W., Dickinson, J. E. & Doherty, D., May 2017, In : American Journal of Obstetrics and Gynecology. 216, 5, p. 434-442

Research output: Contribution to journal › Article

Open Access

37 Citations (Scopus)

2011

Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

Keelan, J., Nitsos, I., Saito, M., Musk, G., Kemp, M., Timmins, M., Li, S., Yaegashi, N. & Newnham, J., 2011, In : American Journal of Obstetrics and Gynecology. 204, p. 10-17

Research output: Contribution to journal › Article

16 Citations (Scopus)

2014

The maternal serological response to intrauterine Ureaplasma sp. infection and prediction of risk of preterm birth

Ireland, D. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 624

Research output: Contribution to journal › Article

Open Access

8 Citations (Scopus)

Re-analysis of the association between perinatal androgens and pragmatic language ability

Whitehouse, A., Maybery, M., Hart, R., Mattes, E., Newnham, J., Sloboda, D. M., Keelan, J. & Hickey, M., 2014, In : Psychoneuroendocrinology. 49, p. 32-33

Research output: Contribution to journal › Letter

1 Citation (Scopus)

2020

The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence

Berman, Y. E., Doherty, D. A., Main, K. M., Frederiksen, H., Keelan, J. A., Newnham, J. P. & Hart, R. J., 16 Oct 2020, In : Environmental Research. 110313.

Research output: Contribution to journal › Article

2014

Whole blood flow cytometric analysis of Ureaplasma-stimulated T-cells from pregnant women

Ireland, D., Friedland, Y. D., Lee-Pullen, T. F., Payne, M. & Keelan, J., 2014, Reproductive Sciences. United States: SAGE Publications Ltd, Vol. 21. p. 237A

Research output: Chapter in Book/Conference paper › Conference paper

2016

IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

Research output: Contribution to journal › Article

4 Citations (Scopus)

T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

Friedland, P., Lee-Pullen, T. F., Nathan, L. A., Watts, R., Keelan, J. A., Payne, M. S. & Ireland, D. J., 2016, In : Journal of Reproductive Immunology. 116, p. 93-97 5 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

2015

Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

Melody, S. M., Vincent, R., Mori, T., Mas, E., Barden, A., Waddell, B. & Keelan, J., 2015, In : Placenta. 36, 1, p. 34-40

Research output: Contribution to journal › Article

9 Citations (Scopus)

In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin

Furfaro, L., Spiller, O. B., Keelan, J. & Payne, M., Sep 2015, In : International Journal of Antimicrobial Agents. 46, 3, p. 319-324

Research output: Contribution to journal › Article

Open Access

File

12 Citations (Scopus)

309 Downloads (Pure)

2014

Detection of bacterial DNA in amniotic fluid. Is there an association with elevated cytokine levels and pregnancy outcome?

Payne, M., Li, S., Doherty, D., Keelan, J. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 112A

Research output: Chapter in Book/Conference paper › Conference paper

Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

Payne, M., Feng, Z., Li, S., Doherty, D., Xu, B., Li, J., Liu, L., Keelan, J., Zhou, YH., Dickinson, J., Hu, Y. & Newnham, J., 30 Sep 2014, In : BMC Pregnancy and Childbirth. 14, p. 340-

Research output: Contribution to journal › Article

Open Access

13 Citations (Scopus)

2015

Testicular function in a birth cohort of young men

Hart, R., Doherty, D., Mclachlan, R. I., Walls, M., Keelan, J., Dickinson, J., Skakkebaek, N. E., Norman, R. J. & Handelsman, D. J., Dec 2015, In : Human Reproduction. 30, 12, p. 2713-2724

Research output: Contribution to journal › Article

Open Access

File

54 Citations (Scopus)

404 Downloads (Pure)

2014

Letter to the editor: “Fatty acids and placental transport: Insight or in vitro artifact?”

Keelan, J., 2014, In : American Journal of Physiology - Cell Physiology. 307, 11, p. C1068

Research output: Contribution to journal › Letter

1 Citation (Scopus)

Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

Stinson, L., Ireland, D., Kemp, M., Payne, M., Stock, S., Newnham, J. & Keelan, J., 1 Mar 2014, In : Reproduction. 147, 3, p. 313-320

Research output: Contribution to journal › Article

Open Access

File

20 Citations (Scopus)

333 Downloads (Pure)

Targeting inflammatory pathways with intra-amniotic CSAIDs for the prevention of preterm birth

Ireland, D., Stinson, L., Charles, A., Kemp, M., Newnham, E. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

Research output: Chapter in Book/Conference paper › Conference paper

Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intraamniotic Antimicrobial Protection In a Pregnant Sheep Model

Keelan, J., Kemp, M., Payne, M., Johnson, D., Stock, S. J., Saito, M., Fernandes, P. & Newnham, J., Jan 2014, In : Antimicrobial Agents and Chemotherapy. 58, 1, p. 447-454

Research output: Contribution to journal › Article

Open Access

23 Citations (Scopus)

2016

Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

Walls, M. L., Hart, R., Keelan, J. A. & Ryan, J., 1 Nov 2016, In : Fertility and Sterility. 106, 6, p. 1392-1398.e5

Research output: Contribution to journal › Article

8 Citations (Scopus)

2020

Maternal perinatal depression, circulating oxytocin levels and childhood emotional disorders at 4 years of age: The importance of psychosocial context

Galbally, M., Watson, S. J., Keelan, J., MacMillan, K. K., Power, J., IJzendoorn, M. V. & Lewis, A. J., Nov 2020, In : Journal of Psychiatric Research. 130, p. 247-253 7 p.

Research output: Contribution to journal › Article

2015

Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity

Hollier, L. P., Keelan, J., Jamnadass, E., Maybery, M., Hickey, M. & Whitehouse, A., Feb 2015, In : Early Human Development. 91, 2, p. 111-117 7 p.

Research output: Contribution to journal › Article

Open Access

File

40 Citations (Scopus)

521 Downloads (Pure)

2020

Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, N. E., Juul, A., Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, K. M. & Frederiksen, H., 1 May 2020, In : Environmental Research. 184, 109231.

Research output: Contribution to journal › Article

2 Citations (Scopus)

2016

Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

Payne, M., Ireland, D., Watts, R., Nathan, L., Furfaro, L., Kemp, M., Keelan, J. & Newnham, J., 18 Oct 2016, In : BMC Pregnancy and Childbirth. 16, 1, p. 1-13 13 p.

Research output: Contribution to journal › Article

Open Access

22 Citations (Scopus)

2017

Applying precision public health to prevent preterm birth

Newnham, J., Kemp, M., White, S., Arrese, C., Hart, R. & Keelan, J., 4 Apr 2017, In : Frontiers in Public Health. 5, 66.

Research output: Contribution to journal › Article

Open Access

17 Citations (Scopus)

2015

Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

Ireland, D., Kemp, M., Miura, Y., Saito, M., Newnham, J. & Keelan, J., May 2015, In : Molecular Human Reproduction. 21, 5, p. 479-489

Research output: Contribution to journal › Article

Open Access

File

25 Citations (Scopus)

260 Downloads (Pure)

2017

The impact of antenatal exposure to environmentally ubiquitous bisphenol A (BPA) on measures of male reproductive function at 20 years of age

Hart, R., Doherty, D., Keelan, J., McLachlan, R., Dickinson, J., Newnham, J., Pennell, C., Norman, R. & Handelsman, D., Jul 2017, In : Human Reproduction. 32, p. 81-82 2 p.

Research output: Contribution to journal › Abstract/Meeting Abstract

2 Citations (Scopus)

2011

Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

Research output: Contribution to journal › Article

26 Citations (Scopus)

Nanoparticulate drug delivery in pregnancy: Placental passage and fetal exposure

Menezes, V., Malek, A. & Keelan, J., 2011, In : Current Pharmaceutical Biotechnology. 12, p. 731-742

Research output: Contribution to journal › Article

43 Citations (Scopus)

2014

Maternal intravenous administration of azithromycin results in significant fetal uptake in a sheep model of second trimester pregnancy

Kemp, M., Miura, Y., Payne, M., Jobe, A., Kallapur, S., Saito, M., Stock, S., Spiller, O. B., Ireland, D., Yaegashi, N., Clarke, M., Hahne, D., Rodger, J., Keelan, J. & Newnham, J., Nov 2014, In : Antimicrobial Agents and Chemotherapy. 58, 11, p. 1-13 11 p.

Research output: Contribution to journal › Article

Open Access

12 Citations (Scopus)

2015

Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood

Whitehouse, A., Gilani, Z., Shafait, F., Mian, A., Tan, D., Maybery, M., Keelan, J., Hart, R., Handelsman, D. J., Goonawardene, M. & Eastwood, P., 7 Oct 2015, In : Proceedings of the Royal Society B: Biological Sciences. 282, 1816, p. 1-9 9 p.

Research output: Contribution to journal › Article

Open Access

File

77 Citations (Scopus)

895 Downloads (Pure)

2014

Measurement of androgen and estrogen concentrations in cord blood: Accuracy, biological interpretation, and applications to understanding human behavioral development

Hollier, L. P., Keelan, J., Hickey, M., Maybery, M. & Whitehouse, A., 2014, In : Frontiers in Endocrinology. 5, MAY, p. 64

Research output: Contribution to journal › Review article

Open Access

39 Citations (Scopus)

Maternal-amniotic-fetal azithromycin pharmacokinetics in a sheep model of second trimester pregnancy

Kemp, M., Keelan, J., Miura, Y., Payne, M., Saito, M., Clarke, M., Stock, S., Spiller, B., Watts, R., Yaegashi, N., Jobe, AH. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 240A

Research output: Chapter in Book/Conference paper › Conference paper

2015

Drugs to block cytokine signaling for the prevention and treatment of inflammation induced preterm birth

Ng, P. Y., Ireland, D. & Keelan, J., 20 Apr 2015, In : Frontiers in Immunology. 6, p. 1-8

Research output: Contribution to journal › Article

Open Access

39 Citations (Scopus)

2020

Comparison of Bacterial DNA Profiles in Mid-Trimester Amniotic Fluid Samples From Preterm and Term Deliveries

Stinson, L., Hallingström, M., Barman, M., Viklund, F., Keelan, J., Kacerovsky, M., Payne, M. & Jacobsson, B., 24 Mar 2020, In : Frontiers in Microbiology. 11, 415.

Research output: Contribution to journal › Article

Open Access

6 Citations (Scopus)

2016

Editorial: Advances in the prevention and treatment of inflammation-associated preterm birth

Keelan, J. A. & Newnham, J. P., 2016, In : Frontiers in Immunology. 7, JUN, p. 5-6 2 p.

Research output: Contribution to journal › Letter

Open Access

4 Citations (Scopus)

2017

Cord blood androgen measurements: the importance of assay validation

Keelan, J. A., Hickey, M. & Hollier, L. P., Jun 2017, In : Human Reproduction. 32, 6, p. 1360-1360 1 p.

Research output: Contribution to journal › Letter

2014

The inﬂuence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study

Hart, R., Doherty, D., Frederiksen, H., Keelan, J., Hickey, M., Sloboda, D., Pennell, C., Newnham, J., Skakkebaek, N. E. & Main, K. M., 2014, In : Reproduction. 147, p. 379-390

Research output: Contribution to journal › Article

49 Citations (Scopus)

2017

The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

Lamont, R. F., Keelan, J. A., Larsson, P. G. & Jørgensen, J. S., 1 Feb 2017, In : Acta Obstetricia et Gynecologica Scandinavica. 96, 2, p. 139-143 5 p.

Research output: Contribution to journal › Comment/debate

10 Citations (Scopus)

2014

Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

Penova-Veselinovic, B., Keelan, J., Newnham, J. & Pennell, C., 2014, p. 25-26.

Research output: Contribution to conference › Abstract

2015

In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

Walls, M., Ryan, J., Keelan, J. & Hart, R., 2015, In : Human Reproduction. 30, 8, p. 1842-1849

Research output: Contribution to journal › Article

21 Citations (Scopus)

2014

Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation: Proof-of-Principle in a Fetal Ovine Model

Saito, M., Payne, M., Miura, Y., Ireland, D., Stock, S., Kallapur, S., Kannan, P., Newnham, J., Kramer, B., Jobe, A., Keelan, J. & Kemp, M., 2014, In : Reproductive Sciences. online, p. 9pp

Research output: Contribution to journal › Article

15 Citations (Scopus)

Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma from the amniotic fluid in an ovine model of intrauterine infection

Miura, Y., Payne, M., Keelan, J., Noe, A., Carter, S., Watts, R., Spiller, B., Jobe, A., Stock, S., Newnham, J. & Kemp, M., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 249A

Research output: Chapter in Book/Conference paper › Conference paper