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• 2017

  Preclinical evaluation of drugs to block inflammation-driven preterm birth

  Ireland, D. J., Nathan, E. A., Li, S., Charles, A. K., Stinson, L. F., Kemp, M. W., Newnham, J. P. & Keelan, J. A., 1 Jan 2017, In : Innate Immunity. 23, 1, p. 20-33 14 p.

  Research output: Contribution to journal › Article

  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Preclinical Drug Evaluations
  • Premature Birth
  • Inflammation
  • Membranes
  11 Citations (Scopus)

• Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

  Ho, D., Leong, J. W., Crew, R. C., Norret, M., House, M. J., Mark, P., Waddell, B. J., Swaminatha Iyer, K. & Keelan, J. A., 6 Jun 2017, In : Scientific Reports. 7, 1, 2866 .

  Research output: Contribution to journal › Article

  Open Access

  • polyglycidyl methacrylate
  • Nanoparticles
  • Mothers
  • Pregnancy
  • Placenta
  15 Citations (Scopus)

• Applying precision public health to prevent preterm birth

  Newnham, J., Kemp, M., White, S., Arrese, C., Hart, R. & Keelan, J., 4 Apr 2017, In : Frontiers in Public Health. 5, 66.

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Public Health
  • Genetic Testing
  • Cervix Uteri
  • Tobacco
  17 Citations (Scopus)
• 2014

  Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

  Payne, M., Feng, Z., Li, S., Doherty, D., Xu, B., Li, J., Liu, L., Keelan, J., Zhou, YH., Dickinson, J., Hu, Y. & Newnham, J., 30 Sep 2014, In : BMC Pregnancy and Childbirth. 14, p. 340-

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Amniotic Fluid
  • Second Pregnancy Trimester
  • Premature Birth
  • Sexual Behavior
  13 Citations (Scopus)
• 2017

  Reducing preterm birth by a state-wide multifaceted program: an implementation study

  Newnham, J. P., White, S. W., Meharry, S., Lee, HS., Pedretti, M. K., Arrese, C. A., Keelan, J. A., Kemp, M. W., Dickinson, J. E. & Doherty, D., May 2017, In : American Journal of Obstetrics and Gynecology. 216, 5, p. 434-442

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Delivery of Health Care
  • Referral and Consultation
  • Western Australia
  • Social Media
  37 Citations (Scopus)
• 2015

  The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study

  Jamnadass, E., Keelan, J., Hollier, L. P., Hickey, M., Maybery, M. & Whitehouse, A., 7 Jun 2015, In : Journal of Neurodevelopmental Disorders. 7, p. 1-12

  Research output: Contribution to journal › Article

  Open Access

  • Androgens
  • Estrogens
  • Autistic Disorder
  • Estetrol
  • Testosterone
  19 Citations (Scopus)
• 2014

  Re-analysis of the association between perinatal androgens and postnatal head circumference growth

  Whitehouse, A., Maybery, M., Hart, R., Sloboda, D. M., Newnham, J., Stanley, F., Hickey, M. & Keelan, J., 2014, In : Developmental Medicine and Child Neurology. 56, p. 1025

  Research output: Contribution to journal › Letter
• 2015

  Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

  Melody, S. M., Vincent, R., Mori, T., Mas, E., Barden, A., Waddell, B. & Keelan, J., 2015, In : Placenta. 36, 1, p. 34-40

  Research output: Contribution to journal › Article

  • Omega-6 Fatty Acids
  • Omega-3 Fatty Acids
  • Cytokines
  • Placenta
  • Fatty Acids
  9 Citations (Scopus)
• 2014

  Re-analysis of the association between perinatal androgens and pragmatic language ability

  Whitehouse, A., Maybery, M., Hart, R., Mattes, E., Newnham, J., Sloboda, D. M., Keelan, J. & Hickey, M., 2014, In : Psychoneuroendocrinology. 49, p. 32-33

  Research output: Contribution to journal › Letter

  1 Citation (Scopus)
• 2017

  Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus

  Guelfi, K., Ong, MJ., Li, S., Wallman, K., Doherty, D., Fournier, P., Newnham, J. & Keelan, J., Oct 2017, In : Metabolism. 75, p. 54-60

  Research output: Contribution to journal › Article

  Open Access

  File

  • Adipokines
  • Gestational Diabetes
  • Insulin Resistance
  • Mothers
  • Adiponectin
  18 Citations (Scopus)

  260 Downloads (Pure)

• Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

  Park, B. Y., Lee, B. K., Burstyn, I., Tabb, L. P., Keelan, J. A., Whitehouse, A. J. O., Croen, L. A., Fallin, M. D., Hertz-Picciotto, I., Montgomery, O. & Newschaffer, C. J., 31 Jan 2017, In : Molecular Autism. 8, 1, p. 1-12 12 p.

  Research output: Contribution to journal › Article

  Open Access

  • Autism Spectrum Disorder
  • Fetal Blood
  • Androgens
  • Cohort Studies
  • Phenotype
  10 Citations (Scopus)
• 2019

  Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 Jan 2019, In : Letters in Applied Microbiology. 68, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Article

  • Biomass
  • Microbiota
  • Polymerase Chain Reaction
  • DNA
  • DNA Contamination
  22 Citations (Scopus)
• 2014

  Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

  Stinson, L., Ireland, D., Kemp, M., Payne, M., Stock, S., Newnham, J. & Keelan, J., 1 Mar 2014, In : Reproduction. 147, 3, p. 313-320

  Research output: Contribution to journal › Article

  Open Access

  File

  • Extraembryonic Membranes
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Sheep
  • Dinoprostone
  • Anti-Inflammatory Agents
  20 Citations (Scopus)

  335 Downloads (Pure)

• The relationship between umbilical cord estrogens and perinatal characteristics

  Hickey, M., Hart, R. & Keelan, J., Jun 2014, In : Cancer Epidemiology, Biomarkers & Prevention. 23, 6, p. 946-952

  Research output: Contribution to journal › Article

  • Umbilical Cord
  • Estrogens
  • Pre-Eclampsia
  • Twins
  • Birth Weight
  30 Citations (Scopus)
• 2015

  Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women

  Friedland, Y. D., Lee-Pullen, T., Nathan, L., Watts, R., Keelan, J., Payne, M. & Ireland, D., 2015, In : Journal of Reproductive Immunology. 109, p. 84-88

  Research output: Contribution to journal › Article
  4 Citations (Scopus)
• 2019

  Re: "amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community" (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

  Payne, M. S., Keelan, J. A. & Stinson, L. F., 12 Feb 2019, In : Microbiome. 7, 1, 3 p., 20.

  Research output: Contribution to journal › Article

  Open Access

  • Amniotic Fluid
  • Microbiota
  • Pregnancy
  3 Citations (Scopus)
• 2017

  Progesterone to prevent preterm birth: the studies are getting better, but there is still room for improvement

  Chung, C. M., van Zijl, M., Keelan, J. A. & Mol, B. W. W., 1 Jun 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 7, p. 1016 1 p.

  Research output: Contribution to journal › Comment/debate
  2 Citations (Scopus)
• 2015

  Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

  Borg, A. J., Yong, H. E. J., Lappas, M., Degrelle, S. A., Keogh, R. J., Da Silva-Costa, F., Fournier, T., Abumaree, M., Keelan, J., Kalionis, B. & Murthi, P., 1 May 2015, In : Reproduction. 149, 5, p. 523-532

  Research output: Contribution to journal › Article

  • Fetal Growth Retardation
  • Trophoblasts
  • STAT3 Transcription Factor
  • Placenta
  • Caspase 8
  15 Citations (Scopus)

• Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2015, In : Molecular and Cellular Endocrinology. 405, p. 52–62

  Research output: Contribution to journal › Article
  5 Citations (Scopus)
• 2014

  High-resolution melt PCR analysis for genotyping of Ureaplasma parvum isolates directly from clinical samples

  Payne, M. S., Tabone, T., Kemp, M. W., Keelan, J. A., Spiller, O. B. & Newnham, J. P., Feb 2014, In : Journal of Clinical Microbiology. 52, 2, p. 599-606 8 p.

  Research output: Contribution to journal › Article

  Open Access
  16 Citations (Scopus)
• 2017

  Recent advances in the prevention of preterm birth

  Keelan, J. & Newnham, J., 2017, In : F1000Research. 6, 6(F1000 Faculty Rev):1139

  Research output: Contribution to journal › Review article

  Open Access
  14 Citations (Scopus)
• 2014

  In vitro maturation (IVM) with a freeze-all embryo protocol may benefit patients with polycystic ovarian syndrome (PCOS)

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, E. & Hart, R., 2014, American Society for Reproductive Medicine. United States: Elsevier, Vol. 102. p. e201

  Research output: Chapter in Book/Conference paper › Conference paper
• 2019

  Prospective study of the association between in-utero exposures to circulating maternal phthalate metabolites and timing of menarche

  Hart, R., Nathan, E., Doherty, D., Frederiksen, H., Keelan, J., Skakkebaek, N., Hickey, M., Newnham, J. & Main, K., Jul 2019, In : Human Reproduction. 34, p. 398-399 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2014

  Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

  Yang, H., Du, L., Tian, X., Fan, Z., Sun, C., Liu, Y., Keelan, J. & Nie, G., 2014, In : Toxicology Letters. 230, 1, p. 10-18

  Research output: Contribution to journal › Article

  • Gold nanoparticles
  • Toxicity
  • Gold
  • Nanoparticles
  • Gestational Age
  35 Citations (Scopus)
• 2011

  ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)
• 2014

  Role of secreted Wnt signaling inhibitors in cross-talk between trophoblast and decidual cells in co-culture

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 294-5A

  Research output: Chapter in Book/Conference paper › Conference paper

• Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy

  Kemp, M., Miura, Y., Payne, M., Watts, R., Megharaj, S., Jobe, A., Kallapur, S., Saito, M., Spiller, O. B., Keelan, J. & Newnham, J., Aug 2014, In : American Journal of Obstetrics and Gynecology. 211, 2, p. 134.e1-134.e9 134.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma Infections
  • Ureaplasma
  • Erythromycin
  • Sheep
  • Mothers
  27 Citations (Scopus)
• 2015

  In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes.

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, L. & Hart, R., 2015, In : Human Reproduction. 30, p. 88-96

  Research output: Contribution to journal › Article
  82 Citations (Scopus)
• 2014

  Measurement of androgen and estrogen concentrations in cord blood: Accuracy, biological interpretation, and applications to understanding human behavioral development

  Hollier, L. P., Keelan, J., Hickey, M., Maybery, M. & Whitehouse, A., 2014, In : Frontiers in Endocrinology. 5, MAY, p. 64

  Research output: Contribution to journal › Review article

  Open Access
  39 Citations (Scopus)
• 2017

  The pregnant women as a drug orphan: a global survey of registered clinical trials of pharmacological interventions in pregnancy

  Scaffidi, J., Mol, B. W. & Keelan, J. A., 1 Jan 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 1, p. 132-140 9 p.

  Research output: Contribution to journal › Article

  • Orphan Drug Production
  • 1-phenyl-3,3-dimethyltriazene
  • Pregnant Women
  • Pharmacology
  • Clinical Trials
  29 Citations (Scopus)
• 2015

  Testicular function in a birth cohort of young men

  Hart, R., Doherty, D., Mclachlan, R. I., Walls, M., Keelan, J., Dickinson, J., Skakkebaek, N. E., Norman, R. J. & Handelsman, D. J., Dec 2015, In : Human Reproduction. 30, 12, p. 2713-2724

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Semen
  • Parturition
  • inhibin B
  • Spermatocele
  54 Citations (Scopus)

  405 Downloads (Pure)
• 2017

  The influence of maternal phthalate exposure upon adult male reproductive function

  Hart, R., Frederiksen, H., Doherty, D. A., Keelan, J., Skakkebaek, N. E., Minaee, N., Handelsman, D., Newnham, J., Dickinson, J., Pennell, C., Norman, R. J. & Main, G. K., Sep 2017, In : Fertility and Sterility. 108, 3, p. E30-E30 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  1 Citation (Scopus)
• 2014

  Amniotic fluid cytokine concentrations at 2nd trimester amniocentesis and pregnancy outcomes in Australian and Chinese cohorts

  Li, S., Feng, Z., Payne, M., Jie, L., Doherty, D., Biyun, X., Lenan, L., Yihua, Z., Dickinson, J., Keelan, J., Yali, H. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 244A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2011

  Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth

  Keelan, J., 2011, In : Journal of Reproductive Immunology. 88, p. 176-184

  Research output: Contribution to journal › Article
  30 Citations (Scopus)
• 2014

  Maternal intravenous administration of azithromycin results in significant fetal uptake in a sheep model of second trimester pregnancy

  Kemp, M., Miura, Y., Payne, M., Jobe, A., Kallapur, S., Saito, M., Stock, S., Spiller, O. B., Ireland, D., Yaegashi, N., Clarke, M., Hahne, D., Rodger, J., Keelan, J. & Newnham, J., Nov 2014, In : Antimicrobial Agents and Chemotherapy. 58, 11, p. 1-13 11 p.

  Research output: Contribution to journal › Article

  Open Access
  12 Citations (Scopus)

• TAK1 inhibition for the prevention of inflammation-induced preterm birth

  Ireland, D., Pugazhenthi, K., Xu, J. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2016

  Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2016, In : Critical Reviews in Microbiology. 43, 3, p. 352-369 18 p.

  Research output: Contribution to journal › Review article

  • Seeds
  • Microbiota
  • Gastrointestinal Microbiome
  • Health
  • Extraembryonic Membranes
  62 Citations (Scopus)
• 2015

  Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

  Ireland, D., Kemp, M., Miura, Y., Saito, M., Newnham, J. & Keelan, J., May 2015, In : Molecular Human Reproduction. 21, 5, p. 479-489

  Research output: Contribution to journal › Article

  Open Access

  File

  • Chorioamnionitis
  • Sheep
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Lipopolysaccharides
  • Pharmacology
  26 Citations (Scopus)

  262 Downloads (Pure)
• 2016

  A new, potent, and placenta-permeable macrolide antibiotic, solithromycin, for the prevention and treatment of bacterial infections in pregnancy

  Keelan, J., Payne, M., Kemp, M., Ireland, D. & Newnham, J., 1 Apr 2016, In : Frontiers in Immunology. 7, p. 1-11 11 p., 111.

  Research output: Contribution to journal › Review article

  Open Access

  • solithromycin
  • Macrolides
  • Bacterial Infections
  • Placenta
  • Anti-Bacterial Agents
  15 Citations (Scopus)
• 2015

  Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood

  Whitehouse, A., Gilani, Z., Shafait, F., Mian, A., Tan, D., Maybery, M., Keelan, J., Hart, R., Handelsman, D. J., Goonawardene, M. & Eastwood, P., 7 Oct 2015, In : Proceedings of the Royal Society B: Biological Sciences. 282, 1816, p. 1-9 9 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • testosterone
  • adulthood
  • Testosterone
  • exposure
  • Femininity
  77 Citations (Scopus)

  902 Downloads (Pure)
• 2014

  Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

  Hollier, L. P., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., Dec 2014, In : Biological Psychology. 103, 1, p. 48-53

  Research output: Contribution to journal › Article

  Open Access

  File

  • Corpus Callosum
  • Testosterone
  • Language
  • Spatial Memory
  • Doppler Transcranial Ultrasonography
  11 Citations (Scopus)

  480 Downloads (Pure)