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• 2016

  IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)
• 2011

  Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

  Keelan, J., Nitsos, I., Saito, M., Musk, G., Kemp, M., Timmins, M., Li, S., Yaegashi, N. & Newnham, J., 2011, In : American Journal of Obstetrics and Gynecology. 204, p. 10-17

  Research output: Contribution to journal › Article
  16 Citations (Scopus)
• 2015

  In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin

  Furfaro, L., Spiller, O. B., Keelan, J. & Payne, M., Sep 2015, In : International Journal of Antimicrobial Agents. 46, 3, p. 319-324

  Research output: Contribution to journal › Article

  Open Access

  File

  • solithromycin
  • Ureaplasma
  • Azithromycin
  • In Vitro Techniques
  12 Citations (Scopus)

  309 Downloads (Pure)
• 2014

  The maternal serological response to intrauterine Ureaplasma sp. infection and prediction of risk of preterm birth

  Ireland, D. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 624

  Research output: Contribution to journal › Article

  Open Access
  8 Citations (Scopus)
• 2015

  Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy

  Keelan, J., Leong, J. W., Ho, D. & Iyer, K., 2015, In : Nanomedicine. 10, 14, p. 2229-2247

  Research output: Contribution to journal › Article

  • Drug delivery
  • Nanoparticles
  • Pregnancy
  • Safety
  • Drug therapy
  43 Citations (Scopus)
• 2014

  Letter to the editor: “Fatty acids and placental transport: Insight or in vitro artifact?”

  Keelan, J., 2014, In : American Journal of Physiology - Cell Physiology. 307, 11, p. C1068

  Research output: Contribution to journal › Letter
  1 Citation (Scopus)

• Role of Wnt signalling in early pregnancy

  Nayeem, S., Arfuso, F., Dharmarajan, A. & Keelan, J., 2014, In : Reproduction, Fertility and Development. accepted 5 August 2014, published online 5 September 2014, p. doi: 10.1071/RD14079

  Research output: Contribution to journal › Review article
  12 Citations (Scopus)
• 2011

  Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)
• 2014

  Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intraamniotic Antimicrobial Protection In a Pregnant Sheep Model

  Keelan, J., Kemp, M., Payne, M., Johnson, D., Stock, S. J., Saito, M., Fernandes, P. & Newnham, J., Jan 2014, In : Antimicrobial Agents and Chemotherapy. 58, 1, p. 447-454

  Research output: Contribution to journal › Article

  Open Access

  • solithromycin
  • Sheep
  • Anti-Bacterial Agents
  • Mothers
  • Amniotic Fluid
  23 Citations (Scopus)

• Detection of bacterial DNA in amniotic fluid. Is there an association with elevated cytokine levels and pregnancy outcome?

  Payne, M., Li, S., Doherty, D., Keelan, J. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 112A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2011

  Nanoparticulate drug delivery in pregnancy: Placental passage and fetal exposure

  Menezes, V., Malek, A. & Keelan, J., 2011, In : Current Pharmaceutical Biotechnology. 12, p. 731-742

  Research output: Contribution to journal › Article
  43 Citations (Scopus)
• 2019

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L., Mathiesen, B., Assens, M., Krause, M., Skakkebaek, N. E., Juul, A., Andersson, A-M., Hart, R., Newnham, J., Keelan, J., Main, K., Pennell, C. & Frederiksen, H., Sep 2019, In : Hormone Research in Paediatrics. 91, p. 118-119 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  6 Citations (Scopus)
• 2014

  Whole blood flow cytometric analysis of Ureaplasma-stimulated T-cells from pregnant women

  Ireland, D., Friedland, Y. D., Lee-Pullen, T. F., Payne, M. & Keelan, J., 2014, Reproductive Sciences. United States: SAGE Publications Ltd, Vol. 21. p. 237A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2016

  Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

  Walls, M. L., Hart, R., Keelan, J. A. & Ryan, J., 1 Nov 2016, In : Fertility and Sterility. 106, 6, p. 1392-1398.e5

  Research output: Contribution to journal › Article

  • Intracytoplasmic Sperm Injections
  • Fertilization
  • Oocytes
  • Polycystic Ovary Syndrome
  • Polar Bodies
  8 Citations (Scopus)
• 2014

  Targeting inflammatory pathways with intra-amniotic CSAIDs for the prevention of preterm birth

  Ireland, D., Stinson, L., Charles, A., Kemp, M., Newnham, E. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2019

  Profiling bacterial communities in low biomass samples: Pitfalls and considerations

  Stinson, L. F., Keelan, J. A. & Payne, M. S., Nov 2019, In : Microbiology Australia. 40, 4, p. 181-185 5 p.

  Research output: Contribution to journal › Review article

  • Biomass
  • Workflow
  • rRNA Genes
  • Built Environment
  • Meconium
  4 Citations (Scopus)
• 2014

  Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

  Keelan, J. & Pugazhenthi, K., 2014, In : Placenta. Accepted 15 September 201, p. 1043-1048

  Research output: Contribution to journal › Article
  10 Citations (Scopus)
• 2015

  Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity

  Hollier, L. P., Keelan, J., Jamnadass, E., Maybery, M., Hickey, M. & Whitehouse, A., Feb 2015, In : Early Human Development. 91, 2, p. 111-117 7 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Umbilical Cord
  • Androgens
  • Estrogens
  • Fetal Blood
  • Testosterone
  40 Citations (Scopus)

  521 Downloads (Pure)
• 2014

  Strategies to prevent preterm birth

  Newnham, J., Dickinson, J., Hart, R., Pennell, C., Arrese, C. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 1-12

  Research output: Contribution to journal › Literature review

  Open Access
  50 Citations (Scopus)
• 2017

  The impact of antenatal exposure to environmentally ubiquitous bisphenol A (BPA) on measures of male reproductive function at 20 years of age

  Hart, R., Doherty, D., Keelan, J., McLachlan, R., Dickinson, J., Newnham, J., Pennell, C., Norman, R. & Handelsman, D., Jul 2017, In : Human Reproduction. 32, p. 81-82 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  2 Citations (Scopus)
• 2015

  Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

  Penova-Veselinovic, B., Keelan, J., Wang, C., Newnham, J. & Pennell, C., Nov 2015, In : Journal of Reproductive Immunology. 112, p. 1-10 10 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Gingival Crevicular Fluid
  • Periodontal Diseases
  • Pregnancy Outcome
  • Pregnancy
  • Interleukin-1
  19 Citations (Scopus)

  396 Downloads (Pure)

• Drugs to block cytokine signaling for the prevention and treatment of inflammation induced preterm birth

  Ng, P. Y., Ireland, D. & Keelan, J., 20 Apr 2015, In : Frontiers in Immunology. 6, p. 1-8

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Cytokines
  • Inflammation
  • Anti-Inflammatory Agents
  • Pharmaceutical Preparations
  39 Citations (Scopus)
• 2017

  The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

  Lamont, R. F., Keelan, J. A., Larsson, P. G. & Jørgensen, J. S., 1 Feb 2017, In : Acta Obstetricia et Gynecologica Scandinavica. 96, 2, p. 139-143 5 p.

  Research output: Contribution to journal › Comment/debate

  • Bacterial Vaginosis
  • Clindamycin
  • Premature Birth
  • Gynecology
  • Obstetrics
  10 Citations (Scopus)

• Cord blood androgen measurements: the importance of assay validation

  Keelan, J. A., Hickey, M. & Hollier, L. P., Jun 2017, In : Human Reproduction. 32, 6, p. 1360-1360 1 p.

  Research output: Contribution to journal › Letter
• 2016

  Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

  Payne, M., Ireland, D., Watts, R., Nathan, L., Furfaro, L., Kemp, M., Keelan, J. & Newnham, J., 18 Oct 2016, In : BMC Pregnancy and Childbirth. 16, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Premature Birth
  • Candida albicans
  • Pregnant Women
  • Genotype
  22 Citations (Scopus)
• 2019

  Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

  Stinson, L., Payne, M. & Keelan, J., Sep 2019, In : Placenta. 85, p. 12-23

  Research output: Contribution to journal › Article

  • Parturition
  • cyclic guanosine monophosphate-adenosine monophosphate
  • Inflammation
  • Poly I-C
  • resiquimod
  3 Citations (Scopus)

• The Not-so-Sterile Womb: Evidence That the Human Fetus Is Exposed to Bacteria Prior to Birth

  Stinson, L. F., Boyce, M. C., Payne, M. S. & Keelan, J. A., 4 Jun 2019, In : Frontiers in Microbiology. 10, 15 p., 1124.

  Research output: Contribution to journal › Article

  Open Access
  60 Citations (Scopus)

• Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 May 2019, In : Letters in Applied Microbiology. 68, 5, p. 378-385 8 p.

  Research output: Contribution to journal › Article

  • propidium monoazide
  • Meconium
  • Bacterial DNA
  • Microbiota
  • Cell-Free Nucleic Acids
  8 Citations (Scopus)
• 2016

  T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

  Friedland, P., Lee-Pullen, T. F., Nathan, L. A., Watts, R., Keelan, J. A., Payne, M. S. & Ireland, D. J., 2016, In : Journal of Reproductive Immunology. 116, p. 93-97 5 p.

  Research output: Contribution to journal › Article

  • Ureaplasma
  • Cytokines
  • T-Lymphocytes
  • Pregnancy
  • Premature Birth
  1 Citation (Scopus)
• 2017

  Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

  Jamnadass, E. S. L., Keelan, J. A., Russell-Smith, S. N., Hickey, M., Maybery, M. T. & Whitehouse, A. J. O., 1 Mar 2017, In : PLoS One. 12, 3, e0173493.

  Research output: Contribution to journal › Article

  Open Access

  • umbilical cord
  • Umbilical Cord
  • androgens
  • Androgens
  • estrogens
• 2016

  Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

  Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Fetal Development
  • Fetal Blood
  • Parturition
  • Estrone
  10 Citations (Scopus)

  310 Downloads (Pure)
• 2014

  Maternal-amniotic-fetal azithromycin pharmacokinetics in a sheep model of second trimester pregnancy

  Kemp, M., Keelan, J., Miura, Y., Payne, M., Saito, M., Clarke, M., Stock, S., Spiller, B., Watts, R., Yaegashi, N., Jobe, AH. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 240A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2016

  Editorial: Advances in the prevention and treatment of inflammation-associated preterm birth

  Keelan, J. A. & Newnham, J. P., 2016, In : Frontiers in Immunology. 7, JUN, p. 5-6 2 p.

  Research output: Contribution to journal › Letter

  Open Access
  4 Citations (Scopus)
• 2014

  The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study

  Hart, R., Doherty, D., Frederiksen, H., Keelan, J., Hickey, M., Sloboda, D., Pennell, C., Newnham, J., Skakkebaek, N. E. & Main, K. M., 2014, In : Reproduction. 147, p. 379-390

  Research output: Contribution to journal › Article
  49 Citations (Scopus)

• Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

  Penova-Veselinovic, B., Keelan, J., Newnham, J. & Pennell, C., 2014, p. 25-26.

  Research output: Contribution to conference › Abstract
• 2015

  In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

  Walls, M., Ryan, J., Keelan, J. & Hart, R., 2015, In : Human Reproduction. 30, 8, p. 1842-1849

  Research output: Contribution to journal › Article

  • Blastocyst
  • Polycystic Ovary Syndrome
  • Embryonic Development
  • Intracytoplasmic Sperm Injections
  • Embryonic Structures
  21 Citations (Scopus)
• 2014

  Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation: Proof-of-Principle in a Fetal Ovine Model

  Saito, M., Payne, M., Miura, Y., Ireland, D., Stock, S., Kallapur, S., Kannan, P., Newnham, J., Kramer, B., Jobe, A., Keelan, J. & Kemp, M., 2014, In : Reproductive Sciences. online, p. 9pp

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma from the amniotic fluid in an ovine model of intrauterine infection

  Miura, Y., Payne, M., Keelan, J., Noe, A., Carter, S., Watts, R., Spiller, B., Jobe, A., Stock, S., Newnham, J. & Kemp, M., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 249A

  Research output: Chapter in Book/Conference paper › Conference paper

• Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection

  Miura, Y., Payne, M., Keelan, J., Noe, A., Carter, S., Watts, R., Spiller, O. B., Jobe, A., Kallapur, S., Saito, M., Stock, S. J., Newnham, J. & Kemp, M., Sep 2014, In : Antimicrobial Agents and Chemotherapy. 58, 9, p. 5413-5420

  Research output: Contribution to journal › Article

  Open Access

  • solithromycin
  • Ureaplasma
  • Azithromycin
  • Amniotic Fluid
  • Sheep
  33 Citations (Scopus)
• 2011

  Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)
• 2016

  Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

  Keelan, J. A. & Newnham, J. P., 2016, Swtitzerland: Frontiers Media SA. 101 p. (Frontiers in Immunology)

  Research output: Book/Report › Edited book/Anthology
• 2017

  Interaction of gold nanorods with genomic DNA

  Kretzmann, J., Ho, D., Toshniwal, P., Evans, C., Norret, M., Nguyen, M., Veder, J-P., Jiang, H., Munshi, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Hurley, L., Kilburn, M., Smith, N. & Iyer, K. S., 20 Aug 2017, In : ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 254, 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2015

  Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

  Keelan, J., Mas, E., D'Vaz, N., Dunstan, J., Li, S., Barden, A., Mark, P., Waddell, B., Prescott, S. & Mori, T., 1 Feb 2015, In : Reproduction. 149, p. 171-178 8 p.

  Research output: Contribution to journal › Article

  Open Access

  • Omega-3 Fatty Acids
  • Docosahexaenoic Acids
  • Lipids
  • Mothers
  • Cytokines
  51 Citations (Scopus)
• 2011

  Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2011, In : Placenta. 32, p. 183-191

  Research output: Contribution to journal › Article
  28 Citations (Scopus)
• 2017

  Preclinical evaluation of drugs to block inflammation-driven preterm birth

  Ireland, D. J., Nathan, E. A., Li, S., Charles, A. K., Stinson, L. F., Kemp, M. W., Newnham, J. P. & Keelan, J. A., 1 Jan 2017, In : Innate Immunity. 23, 1, p. 20-33 14 p.

  Research output: Contribution to journal › Article

  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Preclinical Drug Evaluations
  • Premature Birth
  • Inflammation
  • Membranes
  11 Citations (Scopus)

• Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

  Ho, D., Leong, J. W., Crew, R. C., Norret, M., House, M. J., Mark, P., Waddell, B. J., Swaminatha Iyer, K. & Keelan, J. A., 6 Jun 2017, In : Scientific Reports. 7, 1, 2866 .

  Research output: Contribution to journal › Article

  Open Access

  • polyglycidyl methacrylate
  • Nanoparticles
  • Mothers
  • Pregnancy
  • Placenta
  15 Citations (Scopus)

• Applying precision public health to prevent preterm birth

  Newnham, J., Kemp, M., White, S., Arrese, C., Hart, R. & Keelan, J., 4 Apr 2017, In : Frontiers in Public Health. 5, 66.

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Public Health
  • Genetic Testing
  • Cervix Uteri
  • Tobacco
  17 Citations (Scopus)
• 2014

  Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

  Payne, M., Feng, Z., Li, S., Doherty, D., Xu, B., Li, J., Liu, L., Keelan, J., Zhou, YH., Dickinson, J., Hu, Y. & Newnham, J., 30 Sep 2014, In : BMC Pregnancy and Childbirth. 14, p. 340-

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Amniotic Fluid
  • Second Pregnancy Trimester
  • Premature Birth
  • Sexual Behavior
  13 Citations (Scopus)
• 2017

  Reducing preterm birth by a state-wide multifaceted program: an implementation study

  Newnham, J. P., White, S. W., Meharry, S., Lee, HS., Pedretti, M. K., Arrese, C. A., Keelan, J. A., Kemp, M. W., Dickinson, J. E. & Doherty, D., May 2017, In : American Journal of Obstetrics and Gynecology. 216, 5, p. 434-442

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Delivery of Health Care
  • Referral and Consultation
  • Western Australia
  • Social Media
  37 Citations (Scopus)