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• 2015

  Drugs to block cytokine signaling for the prevention and treatment of inflammation induced preterm birth

  Ng, P. Y., Ireland, D. & Keelan, J., 20 Apr 2015, In : Frontiers in Immunology. 6, p. 1-8

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Cytokines
  • Inflammation
  • Anti-Inflammatory Agents
  • Pharmaceutical Preparations
  38 Citations (Scopus)
• 2011

  Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)
• 2016

  Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

  Walls, M. L., Hart, R., Keelan, J. A. & Ryan, J., 1 Nov 2016, In : Fertility and Sterility. 106, 6, p. 1392-1398.e5

  Research output: Contribution to journal › Article

  • Intracytoplasmic Sperm Injections
  • Fertilization
  • Oocytes
  • Polycystic Ovary Syndrome
  • Polar Bodies
  8 Citations (Scopus)
• 2015

  Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2015, In : Molecular and Cellular Endocrinology. 405, p. 52–62

  Research output: Contribution to journal › Article
  5 Citations (Scopus)
• 2016

  T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

  Friedland, P., Lee-Pullen, T. F., Nathan, L. A., Watts, R., Keelan, J. A., Payne, M. S. & Ireland, D. J., 2016, In : Journal of Reproductive Immunology. 116, p. 93-97 5 p.

  Research output: Contribution to journal › Article

  • Ureaplasma
  • Cytokines
  • T-Lymphocytes
  • Pregnancy
  • Premature Birth
  1 Citation (Scopus)
• 2015

  In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes.

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, L. & Hart, R., 2015, In : Human Reproduction. 30, p. 88-96

  Research output: Contribution to journal › Article
  79 Citations (Scopus)

• Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

  Ireland, D., Kemp, M., Miura, Y., Saito, M., Newnham, J. & Keelan, J., May 2015, In : Molecular Human Reproduction. 21, 5, p. 479-489

  Research output: Contribution to journal › Article

  Open Access

  File

  • Chorioamnionitis
  • Sheep
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Lipopolysaccharides
  • Pharmacology
  25 Citations (Scopus)

  252 Downloads (Pure)
• 2011

  Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Nanoparticulate drug delivery in pregnancy: Placental passage and fetal exposure

  Menezes, V., Malek, A. & Keelan, J., 2011, In : Current Pharmaceutical Biotechnology. 12, p. 731-742

  Research output: Contribution to journal › Article
  43 Citations (Scopus)
• 2015

  Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

  Keelan, J., Mas, E., D'Vaz, N., Dunstan, J., Li, S., Barden, A., Mark, P., Waddell, B., Prescott, S. & Mori, T., 1 Feb 2015, In : Reproduction. 149, p. 171-178 8 p.

  Research output: Contribution to journal › Article

  Open Access

  • Omega-3 Fatty Acids
  • Docosahexaenoic Acids
  • Lipids
  • Mothers
  • Cytokines
  51 Citations (Scopus)
• 2018

  The Relationship Between Pregnancy Exposure to Antidepressant and Atypical Antipsychotic Medications and Placental Weight and Birth Weight Ratio: A Retrospective Cohort Study

  Frayne, J., Nguyen, T., Hauck, Y., Liira, H. & Keelan, J. A., 1 Dec 2018, In : Journal of Clinical Psychopharmacology. 38, 6, p. 563-569 7 p.

  Research output: Contribution to journal › Article

  • Second-Generation Antidepressive Agents
  • Birth Weight
  • Antipsychotic Agents
  • Cohort Studies
  • Retrospective Studies
  1 Citation (Scopus)

• Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study

  Hickey, M., Lawson, L. P., Marino, J. L., Keelan, J. A. & Hart, R., 1 Oct 2018, In : Fertility and Sterility. 110, 5, p. 965-973 9 p.

  Research output: Contribution to journal › Article

  • Sex Hormone-Binding Globulin
  • Menarche
  • Umbilical Cord
  • Steroids
  • Cohort Studies
  2 Citations (Scopus)
• 2020

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, N. E., Juul, A., Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, K. M. & Frederiksen, H., 1 May 2020, In : Environmental Research. 184, 109231.

  Research output: Contribution to journal › Article

  • phthalic acid
  • phthalate
  • serum
  • woman
  • Pregnant Women
  2 Citations (Scopus)
• 2018

  The impact of antenatal Bisphenol A exposure on male reproductive function at 20–22 years of age

  Hart, R. J., Doherty, D. A., Keelan, J. A., Minaee, N. S., Thorstensen, E. B., Dickinson, J. E., Pennell, C. E., Newnham, J. P., McLachlan, R., Norman, R. J. & Handelsman, D. J., 1 Mar 2018, In : Reproductive Biomedicine Online. 36, 3, p. 340-347 8 p.

  Research output: Contribution to journal › Article

  • bisphenol A
  • Mothers
  • Serum
  • inhibin B
  • Varicocele
  13 Citations (Scopus)

• Toll-like receptor-4: A new target for preterm labour pharmacotherapies?

  Robertson, S. A., Wahid, H. H., Chin, P. Y., Hutchinson, M. R., Moldenhauer, L. M. & Keelan, J. A., 2018, In : Current Pharmaceutical Design. 24, 9, p. 960-973

  Research output: Contribution to journal › Review article

  • Premature Obstetric Labor
  • Toll-Like Receptor 4
  • Premature Birth
  • Drug Therapy
  • Uterine Cervical Diseases
  9 Citations (Scopus)
• 2016

  Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

  Payne, M., Ireland, D., Watts, R., Nathan, L., Furfaro, L., Kemp, M., Keelan, J. & Newnham, J., 18 Oct 2016, In : BMC Pregnancy and Childbirth. 16, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Premature Birth
  • Candida albicans
  • Pregnant Women
  • Genotype
  22 Citations (Scopus)
• 2020

  A specific bacterial DNA signature in the vagina of Australian women in midpregnancy predicts high risk of spontaneous preterm birth (the Predict1000 study)

  Payne, M. S., Newnham, J. P., Doherty, D. A., Furfaro, L. L., Pendal, N. L., Loh, D. E. & Keelan, J. A., 27 Aug 2020, In : American Journal of Obstetrics and Gynecology.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Vagina
  • Premature Birth
  • Ureaplasma
  • Lactobacillus
  1 Citation (Scopus)
• 2015

  Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

  Borg, A. J., Yong, H. E. J., Lappas, M., Degrelle, S. A., Keogh, R. J., Da Silva-Costa, F., Fournier, T., Abumaree, M., Keelan, J., Kalionis, B. & Murthi, P., 1 May 2015, In : Reproduction. 149, 5, p. 523-532

  Research output: Contribution to journal › Article

  • Fetal Growth Retardation
  • Trophoblasts
  • STAT3 Transcription Factor
  • Placenta
  • Caspase 8
  15 Citations (Scopus)
• 2016

  IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)
• 2015

  Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women

  Friedland, Y. D., Lee-Pullen, T., Nathan, L., Watts, R., Keelan, J., Payne, M. & Ireland, D., 2015, In : Journal of Reproductive Immunology. 109, p. 84-88

  Research output: Contribution to journal › Article
  4 Citations (Scopus)

• In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

  Walls, M., Ryan, J., Keelan, J. & Hart, R., 2015, In : Human Reproduction. 30, 8, p. 1842-1849

  Research output: Contribution to journal › Article

  • Blastocyst
  • Polycystic Ovary Syndrome
  • Embryonic Development
  • Intracytoplasmic Sperm Injections
  • Embryonic Structures
  21 Citations (Scopus)
• 2011

  ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)
• 2019

  Re: "amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community" (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

  Payne, M. S., Keelan, J. A. & Stinson, L. F., 12 Feb 2019, In : Microbiome. 7, 1, 3 p., 20.

  Research output: Contribution to journal › Article

  Open Access

  • Amniotic Fluid
  • Microbiota
  • Pregnancy
  3 Citations (Scopus)

• Profiling bacterial communities in low biomass samples: Pitfalls and considerations

  Stinson, L. F., Keelan, J. A. & Payne, M. S., Nov 2019, In : Microbiology Australia. 40, 4, p. 181-185 5 p.

  Research output: Contribution to journal › Review article

  • Biomass
  • Workflow
  • rRNA Genes
  • Built Environment
  • Meconium
  3 Citations (Scopus)
• 2015

  Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy

  Keelan, J., Leong, J. W., Ho, D. & Iyer, K., 2015, In : Nanomedicine. 10, 14, p. 2229-2247

  Research output: Contribution to journal › Article

  • Drug delivery
  • Nanoparticles
  • Pregnancy
  • Safety
  • Drug therapy
  42 Citations (Scopus)
• 2011

  Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)

• Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2011, In : Placenta. 32, p. 183-191

  Research output: Contribution to journal › Article
  28 Citations (Scopus)
• 2019

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L., Mathiesen, B., Assens, M., Krause, M., Skakkebaek, N. E., Juul, A., Andersson, A-M., Hart, R., Newnham, J., Keelan, J., Main, K., Pennell, C. & Frederiksen, H., Sep 2019, In : Hormone Research in Paediatrics. 91, p. 118-119 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  6 Citations (Scopus)
• 2013

  Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)

• Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

  Jones, M., Mark, P., Keelan, J., Barden, A., Mas, E., Mori, T. & Waddell, B., Aug 2013, In : Journal of Lipid Research. 54, p. 2247-2254

  Research output: Contribution to journal › Article

  Open Access
  40 Citations (Scopus)
• 2016

  Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

  Keelan, J. A. & Newnham, J. P., 2016, Swtitzerland: Frontiers Media SA. 101 p. (Frontiers in Immunology)

  Research output: Book/Report › Edited book/Anthology

• Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2016, In : Critical Reviews in Microbiology. 43, 3, p. 352-369 18 p.

  Research output: Contribution to journal › Review article

  • Seeds
  • Microbiota
  • Gastrointestinal Microbiome
  • Health
  • Extraembryonic Membranes
  59 Citations (Scopus)

• Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

  Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Fetal Development
  • Fetal Blood
  • Parturition
  • Estrone
  10 Citations (Scopus)

  286 Downloads (Pure)
• 2019

  Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

  Stinson, L., Payne, M. & Keelan, J., Sep 2019, In : Placenta. 85, p. 12-23

  Research output: Contribution to journal › Article

  • Parturition
  • cyclic guanosine monophosphate-adenosine monophosphate
  • Inflammation
  • Poly I-C
  • resiquimod
  3 Citations (Scopus)

• The Not-so-Sterile Womb: Evidence That the Human Fetus Is Exposed to Bacteria Prior to Birth

  Stinson, L. F., Boyce, M. C., Payne, M. S. & Keelan, J. A., 4 Jun 2019, In : Frontiers in Microbiology. 10, 15 p., 1124.

  Research output: Contribution to journal › Article

  Open Access
  49 Citations (Scopus)
• 2013

  Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

  Robinson, M., Whitehouse, A., Jacoby, P., Mattes, E., Sawyer, M. G., Keelan, J. & Hickey, M., 2013, In : PLoS One. 8, 4, p. 8pp

  Research output: Contribution to journal › Article

  Open Access

  File

  • Fetal Blood
  • Testosterone
  • Prospective Studies
  • Child Behavior
  • Checklist
  10 Citations (Scopus)

  11 Downloads (Pure)

• The association between perinatal testosterone concentration and early vocabulary development: A prospective cohort study

  Hollier, L., Mattes, E., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Biological Psychology. 92, p. 212-215

  Research output: Contribution to journal › Article
  25 Citations (Scopus)
• 2018

  Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

  Ho, D., Kretzmann, J., Norret, M., Toshniwal, P., Veder, J. P., Jiang, H., Guagliardo, P., Munshi, A. M. A., Chawla, R., Evans, C., Clemons, T., Nguyen, M., Kretzmann, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Kilburn, M. & 3 others, Hurley, L., Smith, N. & Swaminatha Iyer, K., Dec 2018, In : Nature Nanotechnology. 13, 2

  Research output: Contribution to journal › Article

  • Nanorods
  • Gold
  • DNA
  • nanorods
  • deoxyribonucleic acid
  6 Citations (Scopus)

• The possible impact of antenatal exposure to ubiquitous phthalates upon male reproductive function at 20 years of age

  Hart, R. J., Frederiksen, H., Doherty, D. A., Keelan, J. A., Skakkebaek, N., Minaee, N., McLachlan, R., Newnham, J. P., Dickinson, J. E., Pennell, C. E., Norman, R. & Main, K., 4 Jun 2018, In : Frontiers in Endocrinology. 9, p. 1-11 288.

  Research output: Contribution to journal › Article

  Open Access

  File

  • phthalic acid
  • Serum
  • Testosterone
  • Semen
  • mono-(2-ethylhexyl)phthalate
  14 Citations (Scopus)

  125 Downloads (Pure)
• 2019

  Prospective study of the association between in-utero exposures to circulating maternal phthalate metabolites and timing of menarche

  Hart, R., Nathan, E., Doherty, D., Frederiksen, H., Keelan, J., Skakkebaek, N., Hickey, M., Newnham, J. & Main, K., Jul 2019, In : Human Reproduction. 34, p. 398-399 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 Jan 2019, In : Letters in Applied Microbiology. 68, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Article

  • Biomass
  • Microbiota
  • Polymerase Chain Reaction
  • DNA
  • DNA Contamination
  21 Citations (Scopus)
• 2020

  Comparison of Bacterial DNA Profiles in Mid-Trimester Amniotic Fluid Samples From Preterm and Term Deliveries

  Stinson, L., Hallingström, M., Barman, M., Viklund, F., Keelan, J., Kacerovsky, M., Payne, M. & Jacobsson, B., 24 Mar 2020, In : Frontiers in Microbiology. 11, 415.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Amniotic Fluid
  • rRNA Genes
  • DNA Contamination
  • Technology
  4 Citations (Scopus)
• 2016

  Editorial: Advances in the prevention and treatment of inflammation-associated preterm birth

  Keelan, J. A. & Newnham, J. P., 2016, In : Frontiers in Immunology. 7, JUN, p. 5-6 2 p.

  Research output: Contribution to journal › Letter

  Open Access
  4 Citations (Scopus)
• 2011

  Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

  Keelan, J., Nitsos, I., Saito, M., Musk, G., Kemp, M., Timmins, M., Li, S., Yaegashi, N. & Newnham, J., 2011, In : American Journal of Obstetrics and Gynecology. 204, p. 10-17

  Research output: Contribution to journal › Article
  16 Citations (Scopus)
• 2013

  The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone

  Mark, P., Lewis, J. L., Jones, M., Keelan, J. & Waddell, B., Jul 2013, In : Placenta. 34, 7, p. 559-566

  Research output: Contribution to journal › Article

  • Inner Ear
  • Placenta
  • Dexamethasone
  • Glucocorticoids
  • Pregnancy
  17 Citations (Scopus)
• 2011

  Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth

  Keelan, J., 2011, In : Journal of Reproductive Immunology. 88, p. 176-184

  Research output: Contribution to journal › Article
  30 Citations (Scopus)
• 2015

  Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

  Melody, S. M., Vincent, R., Mori, T., Mas, E., Barden, A., Waddell, B. & Keelan, J., 2015, In : Placenta. 36, 1, p. 34-40

  Research output: Contribution to journal › Article

  • Omega-6 Fatty Acids
  • Omega-3 Fatty Acids
  • Cytokines
  • Placenta
  • Fatty Acids
  9 Citations (Scopus)
• 2020

  Maternal perinatal depression, circulating oxytocin levels and childhood emotional disorders at 4 years of age: The importance of psychosocial context

  Galbally, M., Watson, S. J., Keelan, J., MacMillan, K. K., Power, J., IJzendoorn, M. V. & Lewis, A. J., Nov 2020, In : Journal of Psychiatric Research. 130, p. 247-253 7 p.

  Research output: Contribution to journal › Article

  • Oxytocin
  • Depression
  • Mothers
  • Pregnancy
  • Postpartum Period
• 2013

  Maternal Dietary Omega-3 Fatty Acid Supplementation Reduces Placental Oxidative Stress and Increases Fetal and Placental Growth in the Rat

  Jones, M., Mark, P., Mori, T., Keelan, J. & Waddell, B., 1 Feb 2013, In : Biology of Reproduction. 88, 2, p. 1-8

  Research output: Contribution to journal › Article

  Open Access
  54 Citations (Scopus)
• 2015

  Testicular function in a birth cohort of young men

  Hart, R., Doherty, D., Mclachlan, R. I., Walls, M., Keelan, J., Dickinson, J., Skakkebaek, N. E., Norman, R. J. & Handelsman, D. J., Dec 2015, In : Human Reproduction. 30, 12, p. 2713-2724

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Semen
  • Parturition
  • inhibin B
  • Spermatocele
  53 Citations (Scopus)

  382 Downloads (Pure)