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• 2014

  In vitro maturation (IVM) with a freeze-all embryo protocol may benefit patients with polycystic ovarian syndrome (PCOS)

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, E. & Hart, R., 2014, American Society for Reproductive Medicine. United States: Elsevier, Vol. 102. p. e201

  Research output: Chapter in Book/Conference paper › Conference paper

• Whole blood flow cytometric analysis of Ureaplasma-stimulated T-cells from pregnant women

  Ireland, D., Friedland, Y. D., Lee-Pullen, T. F., Payne, M. & Keelan, J., 2014, Reproductive Sciences. United States: SAGE Publications Ltd, Vol. 21. p. 237A

  Research output: Chapter in Book/Conference paper › Conference paper

• TAK1 inhibition for the prevention of inflammation-induced preterm birth

  Ireland, D., Pugazhenthi, K., Xu, J. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper

• Targeting inflammatory pathways with intra-amniotic CSAIDs for the prevention of preterm birth

  Ireland, D., Stinson, L., Charles, A., Kemp, M., Newnham, E. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper

• Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

  Keelan, J. & Pugazhenthi, K., 2014, In : Placenta. Accepted 15 September 201, p. 1043-1048

  Research output: Contribution to journal › Article
  9 Citations (Scopus)
• 2011

  Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)
• 2014

  The maternal serological response to intrauterine Ureaplasma sp. infection and prediction of risk of preterm birth

  Ireland, D. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 624

  Research output: Contribution to journal › Article

  Open Access
  8 Citations (Scopus)
• 2016

  T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

  Friedland, P., Lee-Pullen, T. F., Nathan, L. A., Watts, R., Keelan, J. A., Payne, M. S. & Ireland, D. J., 2016, In : Journal of Reproductive Immunology. 116, p. 93-97 5 p.

  Research output: Contribution to journal › Article

  • Ureaplasma
  • Cytokines
  • T-Lymphocytes
  • Pregnancy
  • Premature Birth
  1 Citation (Scopus)
• 2014

  Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

  Yang, H., Du, L., Tian, X., Fan, Z., Sun, C., Liu, Y., Keelan, J. & Nie, G., 2014, In : Toxicology Letters. 230, 1, p. 10-18

  Research output: Contribution to journal › Article

  • Gold nanoparticles
  • Toxicity
  • Gold
  • Nanoparticles
  • Gestational Age
  35 Citations (Scopus)
• 2016

  Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

  Walls, M. L., Hart, R., Keelan, J. A. & Ryan, J., 1 Nov 2016, In : Fertility and Sterility. 106, 6, p. 1392-1398.e5

  Research output: Contribution to journal › Article

  • Intracytoplasmic Sperm Injections
  • Fertilization
  • Oocytes
  • Polycystic Ovary Syndrome
  • Polar Bodies
  8 Citations (Scopus)
• 2014

  Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

  Payne, M., Feng, Z., Li, S., Doherty, D., Xu, B., Li, J., Liu, L., Keelan, J., Zhou, YH., Dickinson, J., Hu, Y. & Newnham, J., 30 Sep 2014, In : BMC Pregnancy and Childbirth. 14, p. 340-

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Amniotic Fluid
  • Second Pregnancy Trimester
  • Premature Birth
  • Sexual Behavior
  13 Citations (Scopus)
• 2011

  Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Nanoparticulate drug delivery in pregnancy: Placental passage and fetal exposure

  Menezes, V., Malek, A. & Keelan, J., 2011, In : Current Pharmaceutical Biotechnology. 12, p. 731-742

  Research output: Contribution to journal › Article
  43 Citations (Scopus)
• 2014

  Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma from the amniotic fluid in an ovine model of intrauterine infection

  Miura, Y., Payne, M., Keelan, J., Noe, A., Carter, S., Watts, R., Spiller, B., Jobe, A., Stock, S., Newnham, J. & Kemp, M., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 249A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2013

  Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

  Robinson, M., Whitehouse, A., Jacoby, P., Mattes, E., Sawyer, M. G., Keelan, J. & Hickey, M., 2013, In : PLoS One. 8, 4, p. 8pp

  Research output: Contribution to journal › Article

  Open Access

  File

  • Fetal Blood
  • Testosterone
  • Prospective Studies
  • Child Behavior
  • Checklist
  10 Citations (Scopus)

  11 Downloads (Pure)
• 2014

  Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

  Hollier, L. P., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., Dec 2014, In : Biological Psychology. 103, 1, p. 48-53

  Research output: Contribution to journal › Article

  Open Access

  File

  • Corpus Callosum
  • Testosterone
  • Language
  • Spatial Memory
  • Doppler Transcranial Ultrasonography
  11 Citations (Scopus)

  461 Downloads (Pure)
• 2016

  Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2016, In : Critical Reviews in Microbiology. 43, 3, p. 352-369 18 p.

  Research output: Contribution to journal › Review article

  • Seeds
  • Microbiota
  • Gastrointestinal Microbiome
  • Health
  • Extraembryonic Membranes
  59 Citations (Scopus)
• 2017

  Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

  Ho, D., Leong, J. W., Crew, R. C., Norret, M., House, M. J., Mark, P., Waddell, B. J., Swaminatha Iyer, K. & Keelan, J. A., 6 Jun 2017, In : Scientific Reports. 7, 1, 2866 .

  Research output: Contribution to journal › Article

  Open Access

  • polyglycidyl methacrylate
  • Nanoparticles
  • Mothers
  • Pregnancy
  • Placenta
  14 Citations (Scopus)
• 2018

  Comparison of Meconium DNA extraction methods for use in microbiome studies

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 20 Feb 2018, In : Frontiers in Microbiology. 9, FEB, 270.

  Research output: Contribution to journal › Article

  Open Access

  • Meconium
  • Microbiota
  • DNA
  • Bacterial DNA
  • Polymerase Chain Reaction
  16 Citations (Scopus)
• 2016

  Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

  Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Fetal Development
  • Fetal Blood
  • Parturition
  • Estrone
  10 Citations (Scopus)

  285 Downloads (Pure)
• 2017

  Preclinical evaluation of drugs to block inflammation-driven preterm birth

  Ireland, D. J., Nathan, E. A., Li, S., Charles, A. K., Stinson, L. F., Kemp, M. W., Newnham, J. P. & Keelan, J. A., 1 Jan 2017, In : Innate Immunity. 23, 1, p. 20-33 14 p.

  Research output: Contribution to journal › Article

  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Preclinical Drug Evaluations
  • Premature Birth
  • Inflammation
  • Membranes
  10 Citations (Scopus)
• 2020

  A specific bacterial DNA signature in the vagina of Australian women in midpregnancy predicts high risk of spontaneous preterm birth (the Predict1000 study)

  Payne, M. S., Newnham, J. P., Doherty, D. A., Furfaro, L. L., Pendal, N. L., Loh, D. E. & Keelan, J. A., 27 Aug 2020, In : American Journal of Obstetrics and Gynecology.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Vagina
  • Premature Birth
  • Ureaplasma
  • Lactobacillus
  1 Citation (Scopus)
• 2018

  Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

  Beaudry-Richard, A., Nadeau-Vallée, M., Prairie, É., Maurice, N., Heckel, É., Nezhady, M., Pundir, S., Madaan, A., Boudreault, A., Hou, X., Quiniou, C., Sierra, E. M., Beaulac, A., Lodygensky, G., Robertson, S. A., Keelan, J., Adams-Waldorf, K., Olson, D. M., Rivera, J. C., Lubell, W. D. & 3 others, Joyal, J. S., Bouchard, J. F. & Chemtob, S., 8 Aug 2018, In : Scientific Reports. 8, 1, 11875.

  Research output: Contribution to journal › Article

  Open Access

  • Interleukin-1
  • Inflammation
  • Chorioamnionitis
  • Hyperoxia
  • Retinal Vessels
  9 Citations (Scopus)
• 2014

  Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intraamniotic Antimicrobial Protection In a Pregnant Sheep Model

  Keelan, J., Kemp, M., Payne, M., Johnson, D., Stock, S. J., Saito, M., Fernandes, P. & Newnham, J., Jan 2014, In : Antimicrobial Agents and Chemotherapy. 58, 1, p. 447-454

  Research output: Contribution to journal › Article

  Open Access

  • solithromycin
  • Sheep
  • Anti-Bacterial Agents
  • Mothers
  • Amniotic Fluid
  23 Citations (Scopus)
• 2016

  A new, potent, and placenta-permeable macrolide antibiotic, solithromycin, for the prevention and treatment of bacterial infections in pregnancy

  Keelan, J., Payne, M., Kemp, M., Ireland, D. & Newnham, J., 1 Apr 2016, In : Frontiers in Immunology. 7, p. 1-11 11 p., 111.

  Research output: Contribution to journal › Review article

  Open Access

  • solithromycin
  • Macrolides
  • Bacterial Infections
  • Placenta
  • Anti-Bacterial Agents
  15 Citations (Scopus)
• 2017

  The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

  Lamont, R. F., Keelan, J. A., Larsson, P. G. & Jørgensen, J. S., 1 Feb 2017, In : Acta Obstetricia et Gynecologica Scandinavica. 96, 2, p. 139-143 5 p.

  Research output: Contribution to journal › Comment/debate

  • Bacterial Vaginosis
  • Clindamycin
  • Premature Birth
  • Gynecology
  • Obstetrics
  10 Citations (Scopus)

• Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

  Jamnadass, E. S. L., Keelan, J. A., Russell-Smith, S. N., Hickey, M., Maybery, M. T. & Whitehouse, A. J. O., 1 Mar 2017, In : PLoS One. 12, 3, e0173493.

  Research output: Contribution to journal › Article

  Open Access

  • umbilical cord
  • Umbilical Cord
  • androgens
  • Androgens
  • estrogens
• 2014

  Letter to the editor: “Fatty acids and placental transport: Insight or in vitro artifact?”

  Keelan, J., 2014, In : American Journal of Physiology - Cell Physiology. 307, 11, p. C1068

  Research output: Contribution to journal › Letter
  1 Citation (Scopus)
• 2016

  IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)
• 2011

  ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)
• 2013

  Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)
• 2011

  Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)

• Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2011, In : Placenta. 32, p. 183-191

  Research output: Contribution to journal › Article
  28 Citations (Scopus)
• 2014

  High-resolution melt PCR analysis for genotyping of Ureaplasma parvum isolates directly from clinical samples

  Payne, M. S., Tabone, T., Kemp, M. W., Keelan, J. A., Spiller, O. B. & Newnham, J. P., Feb 2014, In : Journal of Clinical Microbiology. 52, 2, p. 599-606 8 p.

  Research output: Contribution to journal › Article

  Open Access
  16 Citations (Scopus)

• Amniotic fluid cytokine concentrations at 2nd trimester amniocentesis and pregnancy outcomes in Australian and Chinese cohorts

  Li, S., Feng, Z., Payne, M., Jie, L., Doherty, D., Biyun, X., Lenan, L., Yihua, Z., Dickinson, J., Keelan, J., Yali, H. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 244A

  Research output: Chapter in Book/Conference paper › Conference paper

• Strategies to prevent preterm birth

  Newnham, J., Dickinson, J., Hart, R., Pennell, C., Arrese, C. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 1-12

  Research output: Contribution to journal › Literature review

  Open Access
  50 Citations (Scopus)

• The relationship between umbilical cord estrogens and perinatal characteristics

  Hickey, M., Hart, R. & Keelan, J., Jun 2014, In : Cancer Epidemiology, Biomarkers & Prevention. 23, 6, p. 946-952

  Research output: Contribution to journal › Article

  • Umbilical Cord
  • Estrogens
  • Pre-Eclampsia
  • Twins
  • Birth Weight
  30 Citations (Scopus)

• Measurement of androgen and estrogen concentrations in cord blood: Accuracy, biological interpretation, and applications to understanding human behavioral development

  Hollier, L. P., Keelan, J., Hickey, M., Maybery, M. & Whitehouse, A., 2014, In : Frontiers in Endocrinology. 5, MAY, p. 64

  Research output: Contribution to journal › Review article

  Open Access
  38 Citations (Scopus)

• Re-analysis of the association between perinatal androgens and postnatal head circumference growth

  Whitehouse, A., Maybery, M., Hart, R., Sloboda, D. M., Newnham, J., Stanley, F., Hickey, M. & Keelan, J., 2014, In : Developmental Medicine and Child Neurology. 56, p. 1025

  Research output: Contribution to journal › Letter
• 2018

  Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study

  Hickey, M., Lawson, L. P., Marino, J. L., Keelan, J. A. & Hart, R., 1 Oct 2018, In : Fertility and Sterility. 110, 5, p. 965-973 9 p.

  Research output: Contribution to journal › Article

  • Sex Hormone-Binding Globulin
  • Menarche
  • Umbilical Cord
  • Steroids
  • Cohort Studies
  2 Citations (Scopus)
• 2017

  Interaction of gold nanorods with genomic DNA

  Kretzmann, J., Ho, D., Toshniwal, P., Evans, C., Norret, M., Nguyen, M., Veder, J-P., Jiang, H., Munshi, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Hurley, L., Kilburn, M., Smith, N. & Iyer, K. S., 20 Aug 2017, In : ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 254, 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2018

  The impact of antenatal Bisphenol A exposure on male reproductive function at 20–22 years of age

  Hart, R. J., Doherty, D. A., Keelan, J. A., Minaee, N. S., Thorstensen, E. B., Dickinson, J. E., Pennell, C. E., Newnham, J. P., McLachlan, R., Norman, R. J. & Handelsman, D. J., 1 Mar 2018, In : Reproductive Biomedicine Online. 36, 3, p. 340-347 8 p.

  Research output: Contribution to journal › Article

  • bisphenol A
  • Mothers
  • Serum
  • inhibin B
  • Varicocele
  13 Citations (Scopus)
• 2017

  Recent advances in the prevention of preterm birth

  Keelan, J. & Newnham, J., 2017, In : F1000Research. 6, 6(F1000 Faculty Rev):1139

  Research output: Contribution to journal › Review article

  Open Access
  14 Citations (Scopus)
• 2018

  Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

  Keelan, J. A., Feb 2018, In : Journal of Reproductive Immunology. 125, p. 89-99 11 p.

  Research output: Contribution to journal › Review article
  42 Citations (Scopus)

• The Relationship Between Pregnancy Exposure to Antidepressant and Atypical Antipsychotic Medications and Placental Weight and Birth Weight Ratio: A Retrospective Cohort Study

  Frayne, J., Nguyen, T., Hauck, Y., Liira, H. & Keelan, J. A., 1 Dec 2018, In : Journal of Clinical Psychopharmacology. 38, 6, p. 563-569 7 p.

  Research output: Contribution to journal › Article

  • Second-Generation Antidepressive Agents
  • Birth Weight
  • Antipsychotic Agents
  • Cohort Studies
  • Retrospective Studies
  1 Citation (Scopus)
• 2014

  Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

  Stinson, L., Ireland, D., Kemp, M., Payne, M., Stock, S., Newnham, J. & Keelan, J., 1 Mar 2014, In : Reproduction. 147, 3, p. 313-320

  Research output: Contribution to journal › Article

  Open Access

  File

  • Extraembryonic Membranes
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Sheep
  • Dinoprostone
  • Anti-Inflammatory Agents
  19 Citations (Scopus)

  308 Downloads (Pure)
• 2017

  Cord blood androgen measurements: the importance of assay validation

  Keelan, J. A., Hickey, M. & Hollier, L. P., Jun 2017, In : Human Reproduction. 32, 6, p. 1360-1360 1 p.

  Research output: Contribution to journal › Letter

• The influence of maternal phthalate exposure upon adult male reproductive function

  Hart, R., Frederiksen, H., Doherty, D. A., Keelan, J., Skakkebaek, N. E., Minaee, N., Handelsman, D., Newnham, J., Dickinson, J., Pennell, C., Norman, R. J. & Main, G. K., Sep 2017, In : Fertility and Sterility. 108, 3, p. E30-E30 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  1 Citation (Scopus)
• 2016

  Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

  Payne, M., Ireland, D., Watts, R., Nathan, L., Furfaro, L., Kemp, M., Keelan, J. & Newnham, J., 18 Oct 2016, In : BMC Pregnancy and Childbirth. 16, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Premature Birth
  • Candida albicans
  • Pregnant Women
  • Genotype
  22 Citations (Scopus)
• 2014

  Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation: Proof-of-Principle in a Fetal Ovine Model

  Saito, M., Payne, M., Miura, Y., Ireland, D., Stock, S., Kallapur, S., Kannan, P., Newnham, J., Kramer, B., Jobe, A., Keelan, J. & Kemp, M., 2014, In : Reproductive Sciences. online, p. 9pp

  Research output: Contribution to journal › Article
  15 Citations (Scopus)