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• 2014

  In vitro maturation (IVM) with a freeze-all embryo protocol may benefit patients with polycystic ovarian syndrome (PCOS)

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, E. & Hart, R., 2014, American Society for Reproductive Medicine. United States: Elsevier, Vol. 102. p. e201

  Research output: Chapter in Book/Conference paper › Conference paper

• Whole blood flow cytometric analysis of Ureaplasma-stimulated T-cells from pregnant women

  Ireland, D., Friedland, Y. D., Lee-Pullen, T. F., Payne, M. & Keelan, J., 2014, Reproductive Sciences. United States: SAGE Publications Ltd, Vol. 21. p. 237A

  Research output: Chapter in Book/Conference paper › Conference paper

• TAK1 inhibition for the prevention of inflammation-induced preterm birth

  Ireland, D., Pugazhenthi, K., Xu, J. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper

• Targeting inflammatory pathways with intra-amniotic CSAIDs for the prevention of preterm birth

  Ireland, D., Stinson, L., Charles, A., Kemp, M., Newnham, E. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2015

  Drugs to block cytokine signaling for the prevention and treatment of inflammation induced preterm birth

  Ng, P. Y., Ireland, D. & Keelan, J., 20 Apr 2015, In : Frontiers in Immunology. 6, p. 1-8

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Cytokines
  • Inflammation
  • Anti-Inflammatory Agents
  • Pharmaceutical Preparations
  38 Citations (Scopus)
• 2014

  Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

  Keelan, J. & Pugazhenthi, K., 2014, In : Placenta. Accepted 15 September 201, p. 1043-1048

  Research output: Contribution to journal › Article
  9 Citations (Scopus)
• 2011

  Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)
• 2014

  The maternal serological response to intrauterine Ureaplasma sp. infection and prediction of risk of preterm birth

  Ireland, D. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 624

  Research output: Contribution to journal › Article

  Open Access
  8 Citations (Scopus)
• 2016

  T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

  Friedland, P., Lee-Pullen, T. F., Nathan, L. A., Watts, R., Keelan, J. A., Payne, M. S. & Ireland, D. J., 2016, In : Journal of Reproductive Immunology. 116, p. 93-97 5 p.

  Research output: Contribution to journal › Article

  • Ureaplasma
  • Cytokines
  • T-Lymphocytes
  • Pregnancy
  • Premature Birth
  1 Citation (Scopus)
• 2015

  Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2015, In : Molecular and Cellular Endocrinology. 405, p. 52–62

  Research output: Contribution to journal › Article
  5 Citations (Scopus)
• 2014

  Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

  Yang, H., Du, L., Tian, X., Fan, Z., Sun, C., Liu, Y., Keelan, J. & Nie, G., 2014, In : Toxicology Letters. 230, 1, p. 10-18

  Research output: Contribution to journal › Article

  • Gold nanoparticles
  • Toxicity
  • Gold
  • Nanoparticles
  • Gestational Age
  35 Citations (Scopus)
• 2016

  Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

  Walls, M. L., Hart, R., Keelan, J. A. & Ryan, J., 1 Nov 2016, In : Fertility and Sterility. 106, 6, p. 1392-1398.e5

  Research output: Contribution to journal › Article

  • Intracytoplasmic Sperm Injections
  • Fertilization
  • Oocytes
  • Polycystic Ovary Syndrome
  • Polar Bodies
  8 Citations (Scopus)
• 2011

  Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Nanoparticulate drug delivery in pregnancy: Placental passage and fetal exposure

  Menezes, V., Malek, A. & Keelan, J., 2011, In : Current Pharmaceutical Biotechnology. 12, p. 731-742

  Research output: Contribution to journal › Article
  43 Citations (Scopus)
• 2015

  In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes.

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, L. & Hart, R., 2015, In : Human Reproduction. 30, p. 88-96

  Research output: Contribution to journal › Article
  79 Citations (Scopus)

• Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

  Ireland, D., Kemp, M., Miura, Y., Saito, M., Newnham, J. & Keelan, J., May 2015, In : Molecular Human Reproduction. 21, 5, p. 479-489

  Research output: Contribution to journal › Article

  Open Access

  File

  • Chorioamnionitis
  • Sheep
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Lipopolysaccharides
  • Pharmacology
  25 Citations (Scopus)

  252 Downloads (Pure)
• 2014

  Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intraamniotic Antimicrobial Protection In a Pregnant Sheep Model

  Keelan, J., Kemp, M., Payne, M., Johnson, D., Stock, S. J., Saito, M., Fernandes, P. & Newnham, J., Jan 2014, In : Antimicrobial Agents and Chemotherapy. 58, 1, p. 447-454

  Research output: Contribution to journal › Article

  Open Access

  • solithromycin
  • Sheep
  • Anti-Bacterial Agents
  • Mothers
  • Amniotic Fluid
  23 Citations (Scopus)
• 2015

  Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

  Keelan, J., Mas, E., D'Vaz, N., Dunstan, J., Li, S., Barden, A., Mark, P., Waddell, B., Prescott, S. & Mori, T., 1 Feb 2015, In : Reproduction. 149, p. 171-178 8 p.

  Research output: Contribution to journal › Article

  Open Access

  • Omega-3 Fatty Acids
  • Docosahexaenoic Acids
  • Lipids
  • Mothers
  • Cytokines
  51 Citations (Scopus)
• 2017

  The influence of maternal phthalate exposure upon adult male reproductive function

  Hart, R., Frederiksen, H., Doherty, D. A., Keelan, J., Skakkebaek, N. E., Minaee, N., Handelsman, D., Newnham, J., Dickinson, J., Pennell, C., Norman, R. J. & Main, G. K., Sep 2017, In : Fertility and Sterility. 108, 3, p. E30-E30 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  1 Citation (Scopus)

• Progesterone to prevent preterm birth: the studies are getting better, but there is still room for improvement

  Chung, C. M., van Zijl, M., Keelan, J. A. & Mol, B. W. W., 1 Jun 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 7, p. 1016 1 p.

  Research output: Contribution to journal › Comment/debate
  2 Citations (Scopus)
• 2014

  Re-analysis of the association between perinatal androgens and pragmatic language ability

  Whitehouse, A., Maybery, M., Hart, R., Mattes, E., Newnham, J., Sloboda, D. M., Keelan, J. & Hickey, M., 2014, In : Psychoneuroendocrinology. 49, p. 32-33

  Research output: Contribution to journal › Letter

  1 Citation (Scopus)

• Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

  Payne, M., Feng, Z., Li, S., Doherty, D., Xu, B., Li, J., Liu, L., Keelan, J., Zhou, YH., Dickinson, J., Hu, Y. & Newnham, J., 30 Sep 2014, In : BMC Pregnancy and Childbirth. 14, p. 340-

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Amniotic Fluid
  • Second Pregnancy Trimester
  • Premature Birth
  • Sexual Behavior
  13 Citations (Scopus)

• Amniotic fluid cytokine concentrations at 2nd trimester amniocentesis and pregnancy outcomes in Australian and Chinese cohorts

  Li, S., Feng, Z., Payne, M., Jie, L., Doherty, D., Biyun, X., Lenan, L., Yihua, Z., Dickinson, J., Keelan, J., Yali, H. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 244A

  Research output: Chapter in Book/Conference paper › Conference paper

• Strategies to prevent preterm birth

  Newnham, J., Dickinson, J., Hart, R., Pennell, C., Arrese, C. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 1-12

  Research output: Contribution to journal › Literature review

  Open Access
  50 Citations (Scopus)
• 2017

  The impact of antenatal exposure to environmentally ubiquitous bisphenol A (BPA) on measures of male reproductive function at 20 years of age

  Hart, R., Doherty, D., Keelan, J., McLachlan, R., Dickinson, J., Newnham, J., Pennell, C., Norman, R. & Handelsman, D., Jul 2017, In : Human Reproduction. 32, p. 81-82 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  2 Citations (Scopus)
• 2014

  Maternal-amniotic-fetal azithromycin pharmacokinetics in a sheep model of second trimester pregnancy

  Kemp, M., Keelan, J., Miura, Y., Payne, M., Saito, M., Clarke, M., Stock, S., Spiller, B., Watts, R., Yaegashi, N., Jobe, AH. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 240A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2016

  Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

  Payne, M., Ireland, D., Watts, R., Nathan, L., Furfaro, L., Kemp, M., Keelan, J. & Newnham, J., 18 Oct 2016, In : BMC Pregnancy and Childbirth. 16, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Premature Birth
  • Candida albicans
  • Pregnant Women
  • Genotype
  22 Citations (Scopus)
• 2020

  A specific bacterial DNA signature in the vagina of Australian women in midpregnancy predicts high risk of spontaneous preterm birth (the Predict1000 study)

  Payne, M. S., Newnham, J. P., Doherty, D. A., Furfaro, L. L., Pendal, N. L., Loh, D. E. & Keelan, J. A., 27 Aug 2020, In : American Journal of Obstetrics and Gynecology.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Vagina
  • Premature Birth
  • Ureaplasma
  • Lactobacillus
  1 Citation (Scopus)
• 2017

  Preclinical evaluation of drugs to block inflammation-driven preterm birth

  Ireland, D. J., Nathan, E. A., Li, S., Charles, A. K., Stinson, L. F., Kemp, M. W., Newnham, J. P. & Keelan, J. A., 1 Jan 2017, In : Innate Immunity. 23, 1, p. 20-33 14 p.

  Research output: Contribution to journal › Article

  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Preclinical Drug Evaluations
  • Premature Birth
  • Inflammation
  • Membranes
  10 Citations (Scopus)
• 2020

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, N. E., Juul, A., Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, K. M. & Frederiksen, H., 1 May 2020, In : Environmental Research. 184, 109231.

  Research output: Contribution to journal › Article

  • phthalic acid
  • phthalate
  • serum
  • woman
  • Pregnant Women
  2 Citations (Scopus)
• 2016

  Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

  Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Fetal Development
  • Fetal Blood
  • Parturition
  • Estrone
  10 Citations (Scopus)

  287 Downloads (Pure)
• 2015

  Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

  Melody, S. M., Vincent, R., Mori, T., Mas, E., Barden, A., Waddell, B. & Keelan, J., 2015, In : Placenta. 36, 1, p. 34-40

  Research output: Contribution to journal › Article

  • Omega-6 Fatty Acids
  • Omega-3 Fatty Acids
  • Cytokines
  • Placenta
  • Fatty Acids
  9 Citations (Scopus)
• 2014

  Letter to the editor: “Fatty acids and placental transport: Insight or in vitro artifact?”

  Keelan, J., 2014, In : American Journal of Physiology - Cell Physiology. 307, 11, p. C1068

  Research output: Contribution to journal › Letter
  1 Citation (Scopus)
• 2015

  In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

  Walls, M., Ryan, J., Keelan, J. & Hart, R., 2015, In : Human Reproduction. 30, 8, p. 1842-1849

  Research output: Contribution to journal › Article

  • Blastocyst
  • Polycystic Ovary Syndrome
  • Embryonic Development
  • Intracytoplasmic Sperm Injections
  • Embryonic Structures
  21 Citations (Scopus)

• Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women

  Friedland, Y. D., Lee-Pullen, T., Nathan, L., Watts, R., Keelan, J., Payne, M. & Ireland, D., 2015, In : Journal of Reproductive Immunology. 109, p. 84-88

  Research output: Contribution to journal › Article
  4 Citations (Scopus)
• 2016

  IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)
• 2015

  Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

  Borg, A. J., Yong, H. E. J., Lappas, M., Degrelle, S. A., Keogh, R. J., Da Silva-Costa, F., Fournier, T., Abumaree, M., Keelan, J., Kalionis, B. & Murthi, P., 1 May 2015, In : Reproduction. 149, 5, p. 523-532

  Research output: Contribution to journal › Article

  • Fetal Growth Retardation
  • Trophoblasts
  • STAT3 Transcription Factor
  • Placenta
  • Caspase 8
  15 Citations (Scopus)
• 2011

  ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)
• 2013

  Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)
• 2011

  Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)

• Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2011, In : Placenta. 32, p. 183-191

  Research output: Contribution to journal › Article
  28 Citations (Scopus)
• 2014

  High-resolution melt PCR analysis for genotyping of Ureaplasma parvum isolates directly from clinical samples

  Payne, M. S., Tabone, T., Kemp, M. W., Keelan, J. A., Spiller, O. B. & Newnham, J. P., Feb 2014, In : Journal of Clinical Microbiology. 52, 2, p. 599-606 8 p.

  Research output: Contribution to journal › Article

  Open Access
  16 Citations (Scopus)

• The relationship between umbilical cord estrogens and perinatal characteristics

  Hickey, M., Hart, R. & Keelan, J., Jun 2014, In : Cancer Epidemiology, Biomarkers & Prevention. 23, 6, p. 946-952

  Research output: Contribution to journal › Article

  • Umbilical Cord
  • Estrogens
  • Pre-Eclampsia
  • Twins
  • Birth Weight
  30 Citations (Scopus)
• 2017

  Interaction of gold nanorods with genomic DNA

  Kretzmann, J., Ho, D., Toshniwal, P., Evans, C., Norret, M., Nguyen, M., Veder, J-P., Jiang, H., Munshi, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Hurley, L., Kilburn, M., Smith, N. & Iyer, K. S., 20 Aug 2017, In : ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 254, 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2013

  Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

  Jones, M., Mark, P., Keelan, J., Barden, A., Mas, E., Mori, T. & Waddell, B., Aug 2013, In : Journal of Lipid Research. 54, p. 2247-2254

  Research output: Contribution to journal › Article

  Open Access
  40 Citations (Scopus)
• 2017

  The pregnant women as a drug orphan: a global survey of registered clinical trials of pharmacological interventions in pregnancy

  Scaffidi, J., Mol, B. W. & Keelan, J. A., 1 Jan 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 1, p. 132-140 9 p.

  Research output: Contribution to journal › Article

  • Orphan Drug Production
  • 1-phenyl-3,3-dimethyltriazene
  • Pregnant Women
  • Pharmacology
  • Clinical Trials
  28 Citations (Scopus)
• 2015

  Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy

  Keelan, J., Leong, J. W., Ho, D. & Iyer, K., 2015, In : Nanomedicine. 10, 14, p. 2229-2247

  Research output: Contribution to journal › Article

  • Drug delivery
  • Nanoparticles
  • Pregnancy
  • Safety
  • Drug therapy
  42 Citations (Scopus)
• 2014

  Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation: Proof-of-Principle in a Fetal Ovine Model

  Saito, M., Payne, M., Miura, Y., Ireland, D., Stock, S., Kallapur, S., Kannan, P., Newnham, J., Kramer, B., Jobe, A., Keelan, J. & Kemp, M., 2014, In : Reproductive Sciences. online, p. 9pp

  Research output: Contribution to journal › Article
  15 Citations (Scopus)
• 2017

  Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

  Ho, D., Leong, J. W., Crew, R. C., Norret, M., House, M. J., Mark, P., Waddell, B. J., Swaminatha Iyer, K. & Keelan, J. A., 6 Jun 2017, In : Scientific Reports. 7, 1, 2866 .

  Research output: Contribution to journal › Article

  Open Access

  • polyglycidyl methacrylate
  • Nanoparticles
  • Mothers
  • Pregnancy
  • Placenta
  14 Citations (Scopus)

• The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

  Lamont, R. F., Keelan, J. A., Larsson, P. G. & Jørgensen, J. S., 1 Feb 2017, In : Acta Obstetricia et Gynecologica Scandinavica. 96, 2, p. 139-143 5 p.

  Research output: Contribution to journal › Comment/debate

  • Bacterial Vaginosis
  • Clindamycin
  • Premature Birth
  • Gynecology
  • Obstetrics
  10 Citations (Scopus)