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• 2015

  Drugs to block cytokine signaling for the prevention and treatment of inflammation induced preterm birth

  Ng, P. Y., Ireland, D. & Keelan, J., 20 Apr 2015, In : Frontiers in Immunology. 6, p. 1-8

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Cytokines
  • Inflammation
  • Anti-Inflammatory Agents
  • Pharmaceutical Preparations
  38 Citations (Scopus)
• 2011

  Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)
• 2015

  Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2015, In : Molecular and Cellular Endocrinology. 405, p. 52–62

  Research output: Contribution to journal › Article
  5 Citations (Scopus)
• 2011

  Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)
• 2015

  In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes.

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, L. & Hart, R., 2015, In : Human Reproduction. 30, p. 88-96

  Research output: Contribution to journal › Article
  79 Citations (Scopus)

• Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

  Keelan, J., Mas, E., D'Vaz, N., Dunstan, J., Li, S., Barden, A., Mark, P., Waddell, B., Prescott, S. & Mori, T., 1 Feb 2015, In : Reproduction. 149, p. 171-178 8 p.

  Research output: Contribution to journal › Article

  Open Access

  • Omega-3 Fatty Acids
  • Docosahexaenoic Acids
  • Lipids
  • Mothers
  • Cytokines
  51 Citations (Scopus)
• 2012

  Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

  Whitehouse, A., Mattes, E., Maybery, M., Dissanayake, C., Sawyer, M., Jones, R., Pennell, C., Keelan, J. & Hickey, M., 30 Oct 2012, In : Journal of Neurodevelopmental Disorders. 4, p. 25pp

  Research output: Contribution to journal › Article

  Open Access

  • Testosterone
  • Cohort Studies
  • Pregnancy
  • Fetal Blood
  • Population
  40 Citations (Scopus)
• 2018

  Toll-like receptor-4: A new target for preterm labour pharmacotherapies?

  Robertson, S. A., Wahid, H. H., Chin, P. Y., Hutchinson, M. R., Moldenhauer, L. M. & Keelan, J. A., 2018, In : Current Pharmaceutical Design. 24, 9, p. 960-973

  Research output: Contribution to journal › Review article

  • Premature Obstetric Labor
  • Toll-Like Receptor 4
  • Premature Birth
  • Drug Therapy
  • Uterine Cervical Diseases
  9 Citations (Scopus)
• 2015

  Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

  Melody, S. M., Vincent, R., Mori, T., Mas, E., Barden, A., Waddell, B. & Keelan, J., 2015, In : Placenta. 36, 1, p. 34-40

  Research output: Contribution to journal › Article

  • Omega-6 Fatty Acids
  • Omega-3 Fatty Acids
  • Cytokines
  • Placenta
  • Fatty Acids
  9 Citations (Scopus)
• 2018

  Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

  Ho, D., Kretzmann, J., Norret, M., Toshniwal, P., Veder, J. P., Jiang, H., Guagliardo, P., Munshi, A. M. A., Chawla, R., Evans, C., Clemons, T., Nguyen, M., Kretzmann, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Kilburn, M. & 3 others, Hurley, L., Smith, N. & Swaminatha Iyer, K., Dec 2018, In : Nature Nanotechnology. 13, 2

  Research output: Contribution to journal › Article

  • Nanorods
  • Gold
  • DNA
  • nanorods
  • deoxyribonucleic acid
  6 Citations (Scopus)
• 2015

  Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

  Ireland, D., Kemp, M., Miura, Y., Saito, M., Newnham, J. & Keelan, J., May 2015, In : Molecular Human Reproduction. 21, 5, p. 479-489

  Research output: Contribution to journal › Article

  Open Access

  File

  • Chorioamnionitis
  • Sheep
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Lipopolysaccharides
  • Pharmacology
  25 Citations (Scopus)

  255 Downloads (Pure)

• Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy

  Keelan, J., Leong, J. W., Ho, D. & Iyer, K., 2015, In : Nanomedicine. 10, 14, p. 2229-2247

  Research output: Contribution to journal › Article

  • Drug delivery
  • Nanoparticles
  • Pregnancy
  • Safety
  • Drug therapy
  43 Citations (Scopus)

• Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

  Penova-Veselinovic, B., Keelan, J., Wang, C., Newnham, J. & Pennell, C., Nov 2015, In : Journal of Reproductive Immunology. 112, p. 1-10 10 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Gingival Crevicular Fluid
  • Periodontal Diseases
  • Pregnancy Outcome
  • Pregnancy
  • Interleukin-1
  17 Citations (Scopus)

  378 Downloads (Pure)
• 2020

  The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence

  Berman, Y. E., Doherty, D. A., Main, K. M., Frederiksen, H., Keelan, J. A., Newnham, J. P. & Hart, R. J., 16 Oct 2020, In : Environmental Research. 110313.

  Research output: Contribution to journal › Article

  • phthalic acid
  • adolescence
  • phthalate
  • Body Composition
  • Metabolites
• 2019

  Prospective study of the association between in-utero exposures to circulating maternal phthalate metabolites and timing of menarche

  Hart, R., Nathan, E., Doherty, D., Frederiksen, H., Keelan, J., Skakkebaek, N., Hickey, M., Newnham, J. & Main, K., Jul 2019, In : Human Reproduction. 34, p. 398-399 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2013

  Maternal Dietary Omega-3 Fatty Acid Supplementation Reduces Placental Oxidative Stress and Increases Fetal and Placental Growth in the Rat

  Jones, M., Mark, P., Mori, T., Keelan, J. & Waddell, B., 1 Feb 2013, In : Biology of Reproduction. 88, 2, p. 1-8

  Research output: Contribution to journal › Article

  Open Access
  54 Citations (Scopus)
• 2012

  Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

  Yang, H., Sun, C., Fan, Z., Tian, X., Yan, L., Du, L., Liu, Y., Chen, C., Liang, X., Anderson, GJ., Keelan, J., Zhao, Y. & Nie, G., 2012, In : Scientific Reports. 2, p. 847 - 854

  Research output: Contribution to journal › Article

  Open Access
  88 Citations (Scopus)
• 2015

  Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

  Borg, A. J., Yong, H. E. J., Lappas, M., Degrelle, S. A., Keogh, R. J., Da Silva-Costa, F., Fournier, T., Abumaree, M., Keelan, J., Kalionis, B. & Murthi, P., 1 May 2015, In : Reproduction. 149, 5, p. 523-532

  Research output: Contribution to journal › Article

  • Fetal Growth Retardation
  • Trophoblasts
  • STAT3 Transcription Factor
  • Placenta
  • Caspase 8
  15 Citations (Scopus)

• Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women

  Friedland, Y. D., Lee-Pullen, T., Nathan, L., Watts, R., Keelan, J., Payne, M. & Ireland, D., 2015, In : Journal of Reproductive Immunology. 109, p. 84-88

  Research output: Contribution to journal › Article
  4 Citations (Scopus)

• In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

  Walls, M., Ryan, J., Keelan, J. & Hart, R., 2015, In : Human Reproduction. 30, 8, p. 1842-1849

  Research output: Contribution to journal › Article

  • Blastocyst
  • Polycystic Ovary Syndrome
  • Embryonic Development
  • Intracytoplasmic Sperm Injections
  • Embryonic Structures
  21 Citations (Scopus)
• 2012

  Ceramide biosynthesis and metabolism in trophoblast syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Molecular and Cellular Endocrinology. 362, p. 48 - 59

  Research output: Contribution to journal › Article
  11 Citations (Scopus)
• 2011

  ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)

• Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2011, In : Placenta. 32, p. 183-191

  Research output: Contribution to journal › Article
  28 Citations (Scopus)
• 2019

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L., Mathiesen, B., Assens, M., Krause, M., Skakkebaek, N. E., Juul, A., Andersson, A-M., Hart, R., Newnham, J., Keelan, J., Main, K., Pennell, C. & Frederiksen, H., Sep 2019, In : Hormone Research in Paediatrics. 91, p. 118-119 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  6 Citations (Scopus)
• 2013

  Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)

• Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

  Jones, M., Mark, P., Keelan, J., Barden, A., Mas, E., Mori, T. & Waddell, B., Aug 2013, In : Journal of Lipid Research. 54, p. 2247-2254

  Research output: Contribution to journal › Article

  Open Access
  40 Citations (Scopus)

• Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

  Robinson, M., Whitehouse, A., Jacoby, P., Mattes, E., Sawyer, M. G., Keelan, J. & Hickey, M., 2013, In : PLoS One. 8, 4, p. 8pp

  Research output: Contribution to journal › Article

  Open Access

  File

  • Fetal Blood
  • Testosterone
  • Prospective Studies
  • Child Behavior
  • Checklist
  10 Citations (Scopus)

  11 Downloads (Pure)
• 2012

  Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood

  Whitehouse, A., Mattes, E., Maybery, M., Sawyer, M. G., Jacoby, P., Keelan, J. & Hickey, M., 2012, In : Journal of Child Psychology and Psychiatry and Allied Disciplines. 53, 7, p. 726–734

  Research output: Contribution to journal › Article
  54 Citations (Scopus)
• 2013

  The association between perinatal testosterone concentration and early vocabulary development: A prospective cohort study

  Hollier, L., Mattes, E., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Biological Psychology. 92, p. 212-215

  Research output: Contribution to journal › Article
  25 Citations (Scopus)
• 2020

  Maternal perinatal depression, circulating oxytocin levels and childhood emotional disorders at 4 years of age: The importance of psychosocial context

  Galbally, M., Watson, S. J., Keelan, J., MacMillan, K. K., Power, J., IJzendoorn, M. V. & Lewis, A. J., Nov 2020, In : Journal of Psychiatric Research. 130, p. 247-253 7 p.

  Research output: Contribution to journal › Article

  • Oxytocin
  • Depression
  • Mothers
  • Pregnancy
  • Postpartum Period
• 2018

  A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2018, In : Frontiers of Medicine. 5, 135.

  Research output: Contribution to journal › Review article

  Open Access

  • Microbiota
  • Obesity
  • Dysbiosis
  • Noncommunicable Diseases
  • Maternal Age
  46 Citations (Scopus)

• Comparison of Meconium DNA extraction methods for use in microbiome studies

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 20 Feb 2018, In : Frontiers in Microbiology. 9, FEB, 270.

  Research output: Contribution to journal › Article

  Open Access

  • Meconium
  • Microbiota
  • DNA
  • Bacterial DNA
  • Polymerase Chain Reaction
  16 Citations (Scopus)
• 2019

  Re: "amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community" (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

  Payne, M. S., Keelan, J. A. & Stinson, L. F., 12 Feb 2019, In : Microbiome. 7, 1, 3 p., 20.

  Research output: Contribution to journal › Article

  Open Access

  • Amniotic Fluid
  • Microbiota
  • Pregnancy
  3 Citations (Scopus)

• Profiling bacterial communities in low biomass samples: Pitfalls and considerations

  Stinson, L. F., Keelan, J. A. & Payne, M. S., Nov 2019, In : Microbiology Australia. 40, 4, p. 181-185 5 p.

  Research output: Contribution to journal › Review article

  • Biomass
  • Workflow
  • rRNA Genes
  • Built Environment
  • Meconium
  3 Citations (Scopus)
• 2011

  Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)

• Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

  Keelan, J., Nitsos, I., Saito, M., Musk, G., Kemp, M., Timmins, M., Li, S., Yaegashi, N. & Newnham, J., 2011, In : American Journal of Obstetrics and Gynecology. 204, p. 10-17

  Research output: Contribution to journal › Article
  16 Citations (Scopus)
• 2018

  Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

  Keelan, J. A., Feb 2018, In : Journal of Reproductive Immunology. 125, p. 89-99 11 p.

  Research output: Contribution to journal › Review article
  43 Citations (Scopus)

• Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study

  Hickey, M., Lawson, L. P., Marino, J. L., Keelan, J. A. & Hart, R., 1 Oct 2018, In : Fertility and Sterility. 110, 5, p. 965-973 9 p.

  Research output: Contribution to journal › Article

  • Sex Hormone-Binding Globulin
  • Menarche
  • Umbilical Cord
  • Steroids
  • Cohort Studies
  2 Citations (Scopus)
• 2015

  Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood

  Whitehouse, A., Gilani, Z., Shafait, F., Mian, A., Tan, D., Maybery, M., Keelan, J., Hart, R., Handelsman, D. J., Goonawardene, M. & Eastwood, P., 7 Oct 2015, In : Proceedings of the Royal Society B: Biological Sciences. 282, 1816, p. 1-9 9 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • testosterone
  • adulthood
  • Testosterone
  • exposure
  • Femininity
  77 Citations (Scopus)

  855 Downloads (Pure)

• Testicular function in a birth cohort of young men

  Hart, R., Doherty, D., Mclachlan, R. I., Walls, M., Keelan, J., Dickinson, J., Skakkebaek, N. E., Norman, R. J. & Handelsman, D. J., Dec 2015, In : Human Reproduction. 30, 12, p. 2713-2724

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Semen
  • Parturition
  • inhibin B
  • Spermatocele
  53 Citations (Scopus)

  387 Downloads (Pure)
• 2019

  Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 Jan 2019, In : Letters in Applied Microbiology. 68, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Article

  • Biomass
  • Microbiota
  • Polymerase Chain Reaction
  • DNA
  • DNA Contamination
  22 Citations (Scopus)

• Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 May 2019, In : Letters in Applied Microbiology. 68, 5, p. 378-385 8 p.

  Research output: Contribution to journal › Article

  • propidium monoazide
  • Meconium
  • Bacterial DNA
  • Microbiota
  • Cell-Free Nucleic Acids
  8 Citations (Scopus)
• 2012

  Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-kB

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2012, In : Molecular Human Reproduction. 18, 7, p. 341 - 353

  Research output: Contribution to journal › Article
  47 Citations (Scopus)

• Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Reproductive Biomedicine Online. 24, p. 224-234

  Research output: Contribution to journal › Article
  12 Citations (Scopus)
• 2011

  Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth

  Keelan, J., 2011, In : Journal of Reproductive Immunology. 88, p. 176-184

  Research output: Contribution to journal › Article
  30 Citations (Scopus)
• 2013

  The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone

  Mark, P., Lewis, J. L., Jones, M., Keelan, J. & Waddell, B., Jul 2013, In : Placenta. 34, 7, p. 559-566

  Research output: Contribution to journal › Article

  • Inner Ear
  • Placenta
  • Dexamethasone
  • Glucocorticoids
  • Pregnancy
  17 Citations (Scopus)
• 2012

  Androgen concentrations in umbilical cord blood and their association with maternal, fetal and obstetric factors

  Keelan, J., Mattes, E., Tan, H., Dinan, A., Newnham, J., Whitehouse, A., Jacoby, P. & Hickey, M., 20 Aug 2012, In : PLoS One. 7, 8, p. e42827.1-10

  Research output: Contribution to journal › Article

  Open Access

  • Fetal Blood
  • Androgens
  • Obstetrics
  • Testosterone
  • Mothers
  54 Citations (Scopus)
• 2013

  Fetal Testosterone, Socio-Emotional Engagement and Language Development

  Farrant, B., Mattes, E., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Infant and Child Development. 22, 2, p. 119-132

  Research output: Contribution to journal › Article
  9 Citations (Scopus)
• 2015

  The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study

  Jamnadass, E., Keelan, J., Hollier, L. P., Hickey, M., Maybery, M. & Whitehouse, A., 7 Jun 2015, In : Journal of Neurodevelopmental Disorders. 7, p. 1-12

  Research output: Contribution to journal › Article

  Open Access

  • Androgens
  • Estrogens
  • Autistic Disorder
  • Estetrol
  • Testosterone
  18 Citations (Scopus)

• Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity

  Hollier, L. P., Keelan, J., Jamnadass, E., Maybery, M., Hickey, M. & Whitehouse, A., Feb 2015, In : Early Human Development. 91, 2, p. 111-117 7 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Umbilical Cord
  • Androgens
  • Estrogens
  • Fetal Blood
  • Testosterone
  38 Citations (Scopus)

  506 Downloads (Pure)