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• 2014

  In vitro maturation (IVM) with a freeze-all embryo protocol may benefit patients with polycystic ovarian syndrome (PCOS)

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, E. & Hart, R., 2014, American Society for Reproductive Medicine. United States: Elsevier, Vol. 102. p. e201

  Research output: Chapter in Book/Conference paper › Conference paper

• Whole blood flow cytometric analysis of Ureaplasma-stimulated T-cells from pregnant women

  Ireland, D., Friedland, Y. D., Lee-Pullen, T. F., Payne, M. & Keelan, J., 2014, Reproductive Sciences. United States: SAGE Publications Ltd, Vol. 21. p. 237A

  Research output: Chapter in Book/Conference paper › Conference paper

• TAK1 inhibition for the prevention of inflammation-induced preterm birth

  Ireland, D., Pugazhenthi, K., Xu, J. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper

• Targeting inflammatory pathways with intra-amniotic CSAIDs for the prevention of preterm birth

  Ireland, D., Stinson, L., Charles, A., Kemp, M., Newnham, E. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper

• Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

  Keelan, J. & Pugazhenthi, K., 2014, In : Placenta. Accepted 15 September 201, p. 1043-1048

  Research output: Contribution to journal › Article
  9 Citations (Scopus)
• 2011

  Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)
• 2014

  The maternal serological response to intrauterine Ureaplasma sp. infection and prediction of risk of preterm birth

  Ireland, D. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 624

  Research output: Contribution to journal › Article

  Open Access
  8 Citations (Scopus)
• 2012

  Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood

  Whitehouse, A., Mattes, E., Maybery, M., Sawyer, M. G., Jacoby, P., Keelan, J. & Hickey, M., 2012, In : Journal of Child Psychology and Psychiatry and Allied Disciplines. 53, 7, p. 726–734

  Research output: Contribution to journal › Article
  54 Citations (Scopus)
• 2016

  T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

  Friedland, P., Lee-Pullen, T. F., Nathan, L. A., Watts, R., Keelan, J. A., Payne, M. S. & Ireland, D. J., 2016, In : Journal of Reproductive Immunology. 116, p. 93-97 5 p.

  Research output: Contribution to journal › Article

  • Ureaplasma
  • Cytokines
  • T-Lymphocytes
  • Pregnancy
  • Premature Birth
  1 Citation (Scopus)
• 2014

  Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

  Yang, H., Du, L., Tian, X., Fan, Z., Sun, C., Liu, Y., Keelan, J. & Nie, G., 2014, In : Toxicology Letters. 230, 1, p. 10-18

  Research output: Contribution to journal › Article

  • Gold nanoparticles
  • Toxicity
  • Gold
  • Nanoparticles
  • Gestational Age
  35 Citations (Scopus)
• 2016

  Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

  Walls, M. L., Hart, R., Keelan, J. A. & Ryan, J., 1 Nov 2016, In : Fertility and Sterility. 106, 6, p. 1392-1398.e5

  Research output: Contribution to journal › Article

  • Intracytoplasmic Sperm Injections
  • Fertilization
  • Oocytes
  • Polycystic Ovary Syndrome
  • Polar Bodies
  8 Citations (Scopus)
• 2014

  Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

  Payne, M., Feng, Z., Li, S., Doherty, D., Xu, B., Li, J., Liu, L., Keelan, J., Zhou, YH., Dickinson, J., Hu, Y. & Newnham, J., 30 Sep 2014, In : BMC Pregnancy and Childbirth. 14, p. 340-

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Amniotic Fluid
  • Second Pregnancy Trimester
  • Premature Birth
  • Sexual Behavior
  13 Citations (Scopus)
• 2011

  Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Nanoparticulate drug delivery in pregnancy: Placental passage and fetal exposure

  Menezes, V., Malek, A. & Keelan, J., 2011, In : Current Pharmaceutical Biotechnology. 12, p. 731-742

  Research output: Contribution to journal › Article
  43 Citations (Scopus)
• 2014

  Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma from the amniotic fluid in an ovine model of intrauterine infection

  Miura, Y., Payne, M., Keelan, J., Noe, A., Carter, S., Watts, R., Spiller, B., Jobe, A., Stock, S., Newnham, J. & Kemp, M., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 249A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2013

  Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

  Robinson, M., Whitehouse, A., Jacoby, P., Mattes, E., Sawyer, M. G., Keelan, J. & Hickey, M., 2013, In : PLoS One. 8, 4, p. 8pp

  Research output: Contribution to journal › Article

  Open Access

  File

  • Fetal Blood
  • Testosterone
  • Prospective Studies
  • Child Behavior
  • Checklist
  10 Citations (Scopus)

  11 Downloads (Pure)
• 2014

  Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

  Hollier, L. P., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., Dec 2014, In : Biological Psychology. 103, 1, p. 48-53

  Research output: Contribution to journal › Article

  Open Access

  File

  • Corpus Callosum
  • Testosterone
  • Language
  • Spatial Memory
  • Doppler Transcranial Ultrasonography
  11 Citations (Scopus)

  461 Downloads (Pure)
• 2016

  Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2016, In : Critical Reviews in Microbiology. 43, 3, p. 352-369 18 p.

  Research output: Contribution to journal › Review article

  • Seeds
  • Microbiota
  • Gastrointestinal Microbiome
  • Health
  • Extraembryonic Membranes
  59 Citations (Scopus)
• 2019

  The Not-so-Sterile Womb: Evidence That the Human Fetus Is Exposed to Bacteria Prior to Birth

  Stinson, L. F., Boyce, M. C., Payne, M. S. & Keelan, J. A., 4 Jun 2019, In : Frontiers in Microbiology. 10, 15 p., 1124.

  Research output: Contribution to journal › Article

  Open Access
  49 Citations (Scopus)

• Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

  Stinson, L., Payne, M. & Keelan, J., Sep 2019, In : Placenta. 85, p. 12-23

  Research output: Contribution to journal › Article

  • Parturition
  • cyclic guanosine monophosphate-adenosine monophosphate
  • Inflammation
  • Poly I-C
  • resiquimod
  3 Citations (Scopus)
• 2017

  Applying precision public health to prevent preterm birth

  Newnham, J., Kemp, M., White, S., Arrese, C., Hart, R. & Keelan, J., 4 Apr 2017, In : Frontiers in Public Health. 5, 66.

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Public Health
  • Genetic Testing
  • Cervix Uteri
  • Tobacco
  17 Citations (Scopus)

• Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

  Ho, D., Leong, J. W., Crew, R. C., Norret, M., House, M. J., Mark, P., Waddell, B. J., Swaminatha Iyer, K. & Keelan, J. A., 6 Jun 2017, In : Scientific Reports. 7, 1, 2866 .

  Research output: Contribution to journal › Article

  Open Access

  • polyglycidyl methacrylate
  • Nanoparticles
  • Mothers
  • Pregnancy
  • Placenta
  14 Citations (Scopus)
• 2016

  Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

  Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Fetal Development
  • Fetal Blood
  • Parturition
  • Estrone
  10 Citations (Scopus)

  285 Downloads (Pure)
• 2012

  Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

  Yang, H., Sun, C., Fan, Z., Tian, X., Yan, L., Du, L., Liu, Y., Chen, C., Liang, X., Anderson, GJ., Keelan, J., Zhao, Y. & Nie, G., 2012, In : Scientific Reports. 2, p. 847 - 854

  Research output: Contribution to journal › Article

  Open Access
  88 Citations (Scopus)

• Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

  Whitehouse, A., Mattes, E., Maybery, M., Dissanayake, C., Sawyer, M., Jones, R., Pennell, C., Keelan, J. & Hickey, M., 30 Oct 2012, In : Journal of Neurodevelopmental Disorders. 4, p. 25pp

  Research output: Contribution to journal › Article

  Open Access

  • Testosterone
  • Cohort Studies
  • Pregnancy
  • Fetal Blood
  • Population
  40 Citations (Scopus)
• 2016

  IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)
• 2012

  Ceramide biosynthesis and metabolism in trophoblast syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Molecular and Cellular Endocrinology. 362, p. 48 - 59

  Research output: Contribution to journal › Article
  11 Citations (Scopus)
• 2014

  Letter to the editor: “Fatty acids and placental transport: Insight or in vitro artifact?”

  Keelan, J., 2014, In : American Journal of Physiology - Cell Physiology. 307, 11, p. C1068

  Research output: Contribution to journal › Letter
  1 Citation (Scopus)
• 2011

  ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)
• 2019

  Re: "amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community" (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

  Payne, M. S., Keelan, J. A. & Stinson, L. F., 12 Feb 2019, In : Microbiome. 7, 1, 3 p., 20.

  Research output: Contribution to journal › Article

  Open Access

  • Amniotic Fluid
  • Microbiota
  • Pregnancy
  3 Citations (Scopus)
• 2014

  Measurement of androgen and estrogen concentrations in cord blood: Accuracy, biological interpretation, and applications to understanding human behavioral development

  Hollier, L. P., Keelan, J., Hickey, M., Maybery, M. & Whitehouse, A., 2014, In : Frontiers in Endocrinology. 5, MAY, p. 64

  Research output: Contribution to journal › Review article

  Open Access
  38 Citations (Scopus)
• 2019

  Profiling bacterial communities in low biomass samples: Pitfalls and considerations

  Stinson, L. F., Keelan, J. A. & Payne, M. S., Nov 2019, In : Microbiology Australia. 40, 4, p. 181-185 5 p.

  Research output: Contribution to journal › Review article

  • Biomass
  • Workflow
  • rRNA Genes
  • Built Environment
  • Meconium
  3 Citations (Scopus)
• 2014

  Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation: Proof-of-Principle in a Fetal Ovine Model

  Saito, M., Payne, M., Miura, Y., Ireland, D., Stock, S., Kallapur, S., Kannan, P., Newnham, J., Kramer, B., Jobe, A., Keelan, J. & Kemp, M., 2014, In : Reproductive Sciences. online, p. 9pp

  Research output: Contribution to journal › Article
  14 Citations (Scopus)

• Re-analysis of the association between perinatal androgens and postnatal head circumference growth

  Whitehouse, A., Maybery, M., Hart, R., Sloboda, D. M., Newnham, J., Stanley, F., Hickey, M. & Keelan, J., 2014, In : Developmental Medicine and Child Neurology. 56, p. 1025

  Research output: Contribution to journal › Letter

• Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intraamniotic Antimicrobial Protection In a Pregnant Sheep Model

  Keelan, J., Kemp, M., Payne, M., Johnson, D., Stock, S. J., Saito, M., Fernandes, P. & Newnham, J., Jan 2014, In : Antimicrobial Agents and Chemotherapy. 58, 1, p. 447-454

  Research output: Contribution to journal › Article

  Open Access

  • solithromycin
  • Sheep
  • Anti-Bacterial Agents
  • Mothers
  • Amniotic Fluid
  23 Citations (Scopus)

• High-resolution melt PCR analysis for genotyping of Ureaplasma parvum isolates directly from clinical samples

  Payne, M. S., Tabone, T., Kemp, M. W., Keelan, J. A., Spiller, O. B. & Newnham, J. P., Feb 2014, In : Journal of Clinical Microbiology. 52, 2, p. 599-606 8 p.

  Research output: Contribution to journal › Article

  Open Access
  16 Citations (Scopus)

• The relationship between umbilical cord estrogens and perinatal characteristics

  Hickey, M., Hart, R. & Keelan, J., Jun 2014, In : Cancer Epidemiology, Biomarkers & Prevention. 23, 6, p. 946-952

  Research output: Contribution to journal › Article

  • Umbilical Cord
  • Estrogens
  • Pre-Eclampsia
  • Twins
  • Birth Weight
  30 Citations (Scopus)
• 2017

  The pregnant women as a drug orphan: a global survey of registered clinical trials of pharmacological interventions in pregnancy

  Scaffidi, J., Mol, B. W. & Keelan, J. A., 1 Jan 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 1, p. 132-140 9 p.

  Research output: Contribution to journal › Article

  • Orphan Drug Production
  • 1-phenyl-3,3-dimethyltriazene
  • Pregnant Women
  • Pharmacology
  • Clinical Trials
  26 Citations (Scopus)
• 2014

  Amniotic fluid cytokine concentrations at 2nd trimester amniocentesis and pregnancy outcomes in Australian and Chinese cohorts

  Li, S., Feng, Z., Payne, M., Jie, L., Doherty, D., Biyun, X., Lenan, L., Yihua, Z., Dickinson, J., Keelan, J., Yali, H. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 244A

  Research output: Chapter in Book/Conference paper › Conference paper

• Strategies to prevent preterm birth

  Newnham, J., Dickinson, J., Hart, R., Pennell, C., Arrese, C. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 1-12

  Research output: Contribution to journal › Literature review

  Open Access
  50 Citations (Scopus)
• 2013

  Maternal Dietary Omega-3 Fatty Acid Supplementation Reduces Placental Oxidative Stress and Increases Fetal and Placental Growth in the Rat

  Jones, M., Mark, P., Mori, T., Keelan, J. & Waddell, B., 1 Feb 2013, In : Biology of Reproduction. 88, 2, p. 1-8

  Research output: Contribution to journal › Article

  Open Access
  53 Citations (Scopus)
• 2011

  Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)

• Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2011, In : Placenta. 32, p. 183-191

  Research output: Contribution to journal › Article
  28 Citations (Scopus)
• 2019

  Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

  Henriksen, L., Mathiesen, B., Assens, M., Krause, M., Skakkebaek, N. E., Juul, A., Andersson, A-M., Hart, R., Newnham, J., Keelan, J., Main, K., Pennell, C. & Frederiksen, H., Sep 2019, In : Hormone Research in Paediatrics. 91, p. 118-119 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  6 Citations (Scopus)
• 2013

  Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)
• 2012

  Development of a model for functional studies of ABCG2 (breast cancer resistance protein) efflux employing a standard BeWo clone (B24)

  Keelan, J. & Crowe, A., 2012, In : Assay and Drug Development Technologies. 10, p. 476 - 484

  Research output: Contribution to journal › Article
  4 Citations (Scopus)
• 2017

  Interaction of gold nanorods with genomic DNA

  Kretzmann, J., Ho, D., Toshniwal, P., Evans, C., Norret, M., Nguyen, M., Veder, J-P., Jiang, H., Munshi, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Hurley, L., Kilburn, M., Smith, N. & Iyer, K. S., 20 Aug 2017, In : ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 254, 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Recent advances in the prevention of preterm birth

  Keelan, J. & Newnham, J., 2017, In : F1000Research. 6, 6(F1000 Faculty Rev):1139

  Research output: Contribution to journal › Review article

  Open Access
  14 Citations (Scopus)
• 2014

  Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

  Stinson, L., Ireland, D., Kemp, M., Payne, M., Stock, S., Newnham, J. & Keelan, J., 1 Mar 2014, In : Reproduction. 147, 3, p. 313-320

  Research output: Contribution to journal › Article

  Open Access

  File

  • Extraembryonic Membranes
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Sheep
  • Dinoprostone
  • Anti-Inflammatory Agents
  19 Citations (Scopus)

  308 Downloads (Pure)
• 2017

  Cord blood androgen measurements: the importance of assay validation

  Keelan, J. A., Hickey, M. & Hollier, L. P., Jun 2017, In : Human Reproduction. 32, 6, p. 1360-1360 1 p.

  Research output: Contribution to journal › Letter