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• 2018

  The impact of antenatal Bisphenol A exposure on male reproductive function at 20–22 years of age

  Hart, R. J., Doherty, D. A., Keelan, J. A., Minaee, N. S., Thorstensen, E. B., Dickinson, J. E., Pennell, C. E., Newnham, J. P., McLachlan, R., Norman, R. J. & Handelsman, D. J., 1 Mar 2018, In : Reproductive Biomedicine Online. 36, 3, p. 340-347 8 p.

  Research output: Contribution to journal › Article

  • bisphenol A
  • Mothers
  • Serum
  • inhibin B
  • Varicocele
  13 Citations (Scopus)
• 2017

  Recent advances in the prevention of preterm birth

  Keelan, J. & Newnham, J., 2017, In : F1000Research. 6, 6(F1000 Faculty Rev):1139

  Research output: Contribution to journal › Review article

  Open Access
  14 Citations (Scopus)
• 2018

  Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

  Keelan, J. A., Feb 2018, In : Journal of Reproductive Immunology. 125, p. 89-99 11 p.

  Research output: Contribution to journal › Review article
  42 Citations (Scopus)

• The Relationship Between Pregnancy Exposure to Antidepressant and Atypical Antipsychotic Medications and Placental Weight and Birth Weight Ratio: A Retrospective Cohort Study

  Frayne, J., Nguyen, T., Hauck, Y., Liira, H. & Keelan, J. A., 1 Dec 2018, In : Journal of Clinical Psychopharmacology. 38, 6, p. 563-569 7 p.

  Research output: Contribution to journal › Article

  • Second-Generation Antidepressive Agents
  • Birth Weight
  • Antipsychotic Agents
  • Cohort Studies
  • Retrospective Studies
  1 Citation (Scopus)
• 2019

  Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 Jan 2019, In : Letters in Applied Microbiology. 68, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Article

  • Biomass
  • Microbiota
  • Polymerase Chain Reaction
  • DNA
  • DNA Contamination
  20 Citations (Scopus)

• Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 May 2019, In : Letters in Applied Microbiology. 68, 5, p. 378-385 8 p.

  Research output: Contribution to journal › Article

  • propidium monoazide
  • Meconium
  • Bacterial DNA
  • Microbiota
  • Cell-Free Nucleic Acids
  7 Citations (Scopus)
• 2017

  The influence of maternal phthalate exposure upon adult male reproductive function

  Hart, R., Frederiksen, H., Doherty, D. A., Keelan, J., Skakkebaek, N. E., Minaee, N., Handelsman, D., Newnham, J., Dickinson, J., Pennell, C., Norman, R. J. & Main, G. K., Sep 2017, In : Fertility and Sterility. 108, 3, p. E30-E30 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  1 Citation (Scopus)

• Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

  Park, B. Y., Lee, B. K., Burstyn, I., Tabb, L. P., Keelan, J. A., Whitehouse, A. J. O., Croen, L. A., Fallin, M. D., Hertz-Picciotto, I., Montgomery, O. & Newschaffer, C. J., 31 Jan 2017, In : Molecular Autism. 8, 1, p. 1-12 12 p.

  Research output: Contribution to journal › Article

  Open Access

  • Autism Spectrum Disorder
  • Fetal Blood
  • Androgens
  • Cohort Studies
  • Phenotype
  10 Citations (Scopus)
• 2014

  Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

  Stinson, L., Ireland, D., Kemp, M., Payne, M., Stock, S., Newnham, J. & Keelan, J., 1 Mar 2014, In : Reproduction. 147, 3, p. 313-320

  Research output: Contribution to journal › Article

  Open Access

  File

  • Extraembryonic Membranes
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Sheep
  • Dinoprostone
  • Anti-Inflammatory Agents
  19 Citations (Scopus)

  308 Downloads (Pure)
• 2017

  Cord blood androgen measurements: the importance of assay validation

  Keelan, J. A., Hickey, M. & Hollier, L. P., Jun 2017, In : Human Reproduction. 32, 6, p. 1360-1360 1 p.

  Research output: Contribution to journal › Letter

• The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

  Lamont, R. F., Keelan, J. A., Larsson, P. G. & Jørgensen, J. S., 1 Feb 2017, In : Acta Obstetricia et Gynecologica Scandinavica. 96, 2, p. 139-143 5 p.

  Research output: Contribution to journal › Comment/debate

  • Bacterial Vaginosis
  • Clindamycin
  • Premature Birth
  • Gynecology
  • Obstetrics
  10 Citations (Scopus)
• 2014

  Role of secreted Wnt signaling inhibitors in cross-talk between trophoblast and decidual cells in co-culture

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 294-5A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2012

  Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-kB

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2012, In : Molecular Human Reproduction. 18, 7, p. 341 - 353

  Research output: Contribution to journal › Article
  47 Citations (Scopus)

• Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Reproductive Biomedicine Online. 24, p. 224-234

  Research output: Contribution to journal › Article
  12 Citations (Scopus)
• 2014

  Role of Wnt signalling in early pregnancy

  Nayeem, S., Arfuso, F., Dharmarajan, A. & Keelan, J., 2014, In : Reproduction, Fertility and Development. accepted 5 August 2014, published online 5 September 2014, p. doi: 10.1071/RD14079

  Research output: Contribution to journal › Review article
  10 Citations (Scopus)

• Re-analysis of the association between perinatal androgens and pragmatic language ability

  Whitehouse, A., Maybery, M., Hart, R., Mattes, E., Newnham, J., Sloboda, D. M., Keelan, J. & Hickey, M., 2014, In : Psychoneuroendocrinology. 49, p. 32-33

  Research output: Contribution to journal › Letter

  1 Citation (Scopus)

• The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study

  Hart, R., Doherty, D., Frederiksen, H., Keelan, J., Hickey, M., Sloboda, D., Pennell, C., Newnham, J., Skakkebaek, N. E. & Main, K. M., 2014, In : Reproduction. 147, p. 379-390

  Research output: Contribution to journal › Article
  49 Citations (Scopus)

• Maternal-amniotic-fetal azithromycin pharmacokinetics in a sheep model of second trimester pregnancy

  Kemp, M., Keelan, J., Miura, Y., Payne, M., Saito, M., Clarke, M., Stock, S., Spiller, B., Watts, R., Yaegashi, N., Jobe, AH. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 240A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2013

  Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

  Jones, M., Mark, P., Keelan, J., Barden, A., Mas, E., Mori, T. & Waddell, B., Aug 2013, In : Journal of Lipid Research. 54, p. 2247-2254

  Research output: Contribution to journal › Article

  Open Access
  39 Citations (Scopus)
• 2012

  Androgen concentrations in umbilical cord blood and their association with maternal, fetal and obstetric factors

  Keelan, J., Mattes, E., Tan, H., Dinan, A., Newnham, J., Whitehouse, A., Jacoby, P. & Hickey, M., 20 Aug 2012, In : PLoS One. 7, 8, p. e42827.1-10

  Research output: Contribution to journal › Article

  Open Access

  • Fetal Blood
  • Androgens
  • Obstetrics
  • Testosterone
  • Mothers
  54 Citations (Scopus)
• 2014

  Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

  Penova-Veselinovic, B., Keelan, J., Newnham, J. & Pennell, C., 2014, p. 25-26.

  Research output: Contribution to conference › Abstract

• Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy

  Kemp, M., Miura, Y., Payne, M., Watts, R., Megharaj, S., Jobe, A., Kallapur, S., Saito, M., Spiller, O. B., Keelan, J. & Newnham, J., Aug 2014, In : American Journal of Obstetrics and Gynecology. 211, 2, p. 134.e1-134.e9 134.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma Infections
  • Ureaplasma
  • Erythromycin
  • Sheep
  • Mothers
  27 Citations (Scopus)

• Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection

  Miura, Y., Payne, M., Keelan, J., Noe, A., Carter, S., Watts, R., Spiller, O. B., Jobe, A., Kallapur, S., Saito, M., Stock, S. J., Newnham, J. & Kemp, M., Sep 2014, In : Antimicrobial Agents and Chemotherapy. 58, 9, p. 5413-5420

  Research output: Contribution to journal › Article

  Open Access

  • solithromycin
  • Ureaplasma
  • Azithromycin
  • Amniotic Fluid
  • Sheep
  33 Citations (Scopus)
• 2016

  Editorial: Advances in the prevention and treatment of inflammation-associated preterm birth

  Keelan, J. A. & Newnham, J. P., 2016, In : Frontiers in Immunology. 7, JUN, p. 5-6 2 p.

  Research output: Contribution to journal › Letter

  Open Access
  4 Citations (Scopus)
• 2014

  Detection of bacterial DNA in amniotic fluid. Is there an association with elevated cytokine levels and pregnancy outcome?

  Payne, M., Li, S., Doherty, D., Keelan, J. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 112A

  Research output: Chapter in Book/Conference paper › Conference paper
• 2013

  The association between perinatal testosterone concentration and early vocabulary development: A prospective cohort study

  Hollier, L., Mattes, E., Maybery, M., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Biological Psychology. 92, p. 212-215

  Research output: Contribution to journal › Article
  25 Citations (Scopus)
• 2011

  Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth

  Keelan, J., 2011, In : Journal of Reproductive Immunology. 88, p. 176-184

  Research output: Contribution to journal › Article
  30 Citations (Scopus)
• 2014

  Maternal intravenous administration of azithromycin results in significant fetal uptake in a sheep model of second trimester pregnancy

  Kemp, M., Miura, Y., Payne, M., Jobe, A., Kallapur, S., Saito, M., Stock, S., Spiller, O. B., Ireland, D., Yaegashi, N., Clarke, M., Hahne, D., Rodger, J., Keelan, J. & Newnham, J., Nov 2014, In : Antimicrobial Agents and Chemotherapy. 58, 11, p. 1-13 11 p.

  Research output: Contribution to journal › Article

  Open Access
  12 Citations (Scopus)
• 2013

  Fetal Testosterone, Socio-Emotional Engagement and Language Development

  Farrant, B., Mattes, E., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Infant and Child Development. 22, 2, p. 119-132

  Research output: Contribution to journal › Article
  9 Citations (Scopus)

• The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone

  Mark, P., Lewis, J. L., Jones, M., Keelan, J. & Waddell, B., Jul 2013, In : Placenta. 34, 7, p. 559-566

  Research output: Contribution to journal › Article

  • Inner Ear
  • Placenta
  • Dexamethasone
  • Glucocorticoids
  • Pregnancy
  17 Citations (Scopus)
• 2011

  Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

  Keelan, J., Nitsos, I., Saito, M., Musk, G., Kemp, M., Timmins, M., Li, S., Yaegashi, N. & Newnham, J., 2011, In : American Journal of Obstetrics and Gynecology. 204, p. 10-17

  Research output: Contribution to journal › Article
  16 Citations (Scopus)
• 2016

  Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

  Keelan, J. A. & Newnham, J. P., 2016, Swtitzerland: Frontiers Media SA. 101 p. (Frontiers in Immunology)

  Research output: Book/Report › Edited book/Anthology
• 2018

  Toll-like receptor-4: A new target for preterm labour pharmacotherapies?

  Robertson, S. A., Wahid, H. H., Chin, P. Y., Hutchinson, M. R., Moldenhauer, L. M. & Keelan, J. A., 2018, In : Current Pharmaceutical Design. 24, 9, p. 960-973

  Research output: Contribution to journal › Review article

  • Premature Obstetric Labor
  • Toll-Like Receptor 4
  • Premature Birth
  • Drug Therapy
  • Uterine Cervical Diseases
  9 Citations (Scopus)
• 2017

  The impact of antenatal exposure to environmentally ubiquitous bisphenol A (BPA) on measures of male reproductive function at 20 years of age

  Hart, R., Doherty, D., Keelan, J., McLachlan, R., Dickinson, J., Newnham, J., Pennell, C., Norman, R. & Handelsman, D., Jul 2017, In : Human Reproduction. 32, p. 81-82 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

  2 Citations (Scopus)
• 2018

  The possible impact of antenatal exposure to ubiquitous phthalates upon male reproductive function at 20 years of age

  Hart, R. J., Frederiksen, H., Doherty, D. A., Keelan, J. A., Skakkebaek, N., Minaee, N., McLachlan, R., Newnham, J. P., Dickinson, J. E., Pennell, C. E., Norman, R. & Main, K., 4 Jun 2018, In : Frontiers in Endocrinology. 9, p. 1-11 288.

  Research output: Contribution to journal › Article

  Open Access

  File

  • phthalic acid
  • Serum
  • Testosterone
  • Semen
  • mono-(2-ethylhexyl)phthalate
  13 Citations (Scopus)

  125 Downloads (Pure)
• 2017

  Reducing preterm birth by a state-wide multifaceted program: an implementation study

  Newnham, J. P., White, S. W., Meharry, S., Lee, HS., Pedretti, M. K., Arrese, C. A., Keelan, J. A., Kemp, M. W., Dickinson, J. E. & Doherty, D., May 2017, In : American Journal of Obstetrics and Gynecology. 216, 5, p. 434-442

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Delivery of Health Care
  • Referral and Consultation
  • Western Australia
  • Social Media
  35 Citations (Scopus)
• 2018

  Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

  Yang, H., Du, L., Wu, G., Wu, Z. & Keelan, J. A., 3 Dec 2018, In : Molecular Medicine. 24, 16 p., 62.

  Research output: Contribution to journal › Article

  Open Access
  8 Citations (Scopus)

• Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

  Ho, D., Kretzmann, J., Norret, M., Toshniwal, P., Veder, J. P., Jiang, H., Guagliardo, P., Munshi, A. M. A., Chawla, R., Evans, C., Clemons, T., Nguyen, M., Kretzmann, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Kilburn, M. & 3 others, Hurley, L., Smith, N. & Swaminatha Iyer, K., Dec 2018, In : Nature Nanotechnology. 13, 2

  Research output: Contribution to journal › Article

  • Nanorods
  • Gold
  • DNA
  • nanorods
  • deoxyribonucleic acid
  6 Citations (Scopus)
• 2019

  Prospective study of the association between in-utero exposures to circulating maternal phthalate metabolites and timing of menarche

  Hart, R., Nathan, E., Doherty, D., Frederiksen, H., Keelan, J., Skakkebaek, N., Hickey, M., Newnham, J. & Main, K., Jul 2019, In : Human Reproduction. 34, p. 398-399 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2017

  Preclinical evaluation of drugs to block inflammation-driven preterm birth

  Ireland, D. J., Nathan, E. A., Li, S., Charles, A. K., Stinson, L. F., Kemp, M. W., Newnham, J. P. & Keelan, J. A., 1 Jan 2017, In : Innate Immunity. 23, 1, p. 20-33 14 p.

  Research output: Contribution to journal › Article

  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Preclinical Drug Evaluations
  • Premature Birth
  • Inflammation
  • Membranes
  10 Citations (Scopus)

• Progesterone to prevent preterm birth: the studies are getting better, but there is still room for improvement

  Chung, C. M., van Zijl, M., Keelan, J. A. & Mol, B. W. W., 1 Jun 2017, In : BJOG: an International Journal of Obstetrics and Gynaecology. 124, 7, p. 1016 1 p.

  Research output: Contribution to journal › Comment/debate
  2 Citations (Scopus)

• Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus

  Guelfi, K., Ong, MJ., Li, S., Wallman, K., Doherty, D., Fournier, P., Newnham, J. & Keelan, J., Oct 2017, In : Metabolism. 75, p. 54-60

  Research output: Contribution to journal › Article

  Open Access

  File

  • Adipokines
  • Gestational Diabetes
  • Insulin Resistance
  • Mothers
  • Adiponectin
  17 Citations (Scopus)

  219 Downloads (Pure)
• 2016

  A new, potent, and placenta-permeable macrolide antibiotic, solithromycin, for the prevention and treatment of bacterial infections in pregnancy

  Keelan, J., Payne, M., Kemp, M., Ireland, D. & Newnham, J., 1 Apr 2016, In : Frontiers in Immunology. 7, p. 1-11 11 p., 111.

  Research output: Contribution to journal › Review article

  Open Access

  • solithromycin
  • Macrolides
  • Bacterial Infections
  • Placenta
  • Anti-Bacterial Agents
  15 Citations (Scopus)

• Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

  Payne, M., Ireland, D., Watts, R., Nathan, L., Furfaro, L., Kemp, M., Keelan, J. & Newnham, J., 18 Oct 2016, In : BMC Pregnancy and Childbirth. 16, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ureaplasma
  • Premature Birth
  • Candida albicans
  • Pregnant Women
  • Genotype
  22 Citations (Scopus)
• 2017

  Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

  Jamnadass, E. S. L., Keelan, J. A., Russell-Smith, S. N., Hickey, M., Maybery, M. T. & Whitehouse, A. J. O., 1 Mar 2017, In : PLoS One. 12, 3, e0173493.

  Research output: Contribution to journal › Article

  Open Access

  • umbilical cord
  • Umbilical Cord
  • androgens
  • Androgens
  • estrogens
• 2013

  Maternal Dietary Omega-3 Fatty Acid Supplementation Reduces Placental Oxidative Stress and Increases Fetal and Placental Growth in the Rat

  Jones, M., Mark, P., Mori, T., Keelan, J. & Waddell, B., 1 Feb 2013, In : Biology of Reproduction. 88, 2, p. 1-8

  Research output: Contribution to journal › Article

  Open Access
  54 Citations (Scopus)