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  • Jiake Xu
2019

MiR-214 Attenuates the Osteogenic Effects of Mechanical Loading on Osteoblasts

Yuan, Y., Guo, J., Zhang, L., Tong, X., Zhang, S., Zhou, X., Zhang, M., Chen, X., Lei, L., Li, H., Liu, T. C. Y., Xu, J. & Zou, J., Dec 2019, In : International Journal of Sports Medicine. 40, 14, p. 931-940 10 p.

Research output: Contribution to journalArticle

2019

Osthole inhibits osteoclasts formation and bone resorption by regulating NF-κB signaling and NFATc1 activations stimulated by RANKL

Ma, Y., Wang, L., Zheng, S., Xu, J., Pan, Y., Tu, P., Sun, J. & Guo, Y., 1 Sep 2019, In : Journal of Cellular Biochemistry. 120, 9, p. 16052-16061 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Molecular structure and the role of high-temperature requirement protein 1 in skeletal disorders and cancers

Li, Y., Yuan, J., Rothzerg, E., Wu, X., Xu, H., Zhu, S. & Xu, J., 22 Dec 2019, In : Cell Proliferation. e12746.

Research output: Contribution to journalReview article

Open Access
2018

MicroRNAs as Potential Targets for Treatment of Osteoclast-Related Diseases

Li, H., Zhai, Z., Qu, X., Xu, J., Qin, A. & Dai, K., 2018, In : Current Drug Targets. 19, 5, p. 422-431 10 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2019

Pathological mechanisms and therapeutic outlooks for arthrofibrosis

Usher, K. M., Zhu, S., Mavropalias, G., Carrino, J. A., Zhao, J. & Xu, J., 1 Dec 2019, In : Bone Research. 7, 1, 9.

Research output: Contribution to journalReview article

Open Access
6 Citations (Scopus)
2015

Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis

Zawawi, M. S. F., Marino, V., Perilli, E., Cantley, M. D., Xu, J., Purdue, P. E., Dharmapatni, A. A. S. S. K., Haynes, D. R. & Crotti, T. N., 2015, In : Journal of Biomedical Materials Research Part A. 103, 11, p. 3572-3579

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016

Deficiency of sorting nexin 10 prevents bone erosion in collagen-induced mouse arthritis through promoting NFATc1 degradation

Zhou, C., You, Y., Shen, W., Zhu, Y. Z., Peng, J., Feng, H. T., Wang, Y., Li, D., Shao, W. W., Li, C. X., Li, W. Z., Xu, J. & Shen, X., 2016, In : Annals of the Rheumatic Diseases. n/a, p. 1-8

Research output: Contribution to journalArticle

14 Citations (Scopus)
2020

Jatrophane Diterpenoids from Euphorbia esula as Inhibitors of RANKL-Induced Osteoclastogenesis

Yuan, S., Hua, P., Zhao, C., Zhou, H., Xu, J., Xu, J. & Gu, Q., 1 Jan 2020, (Accepted/In press) In : Journal of Natural Products.

Research output: Contribution to journalArticle

2014

Differential expression of extracellular-Signal-Regulated kinase 5 (ERK5) in normal and degenerated human nucleus pulposus tissues and cells

Liang, W., Fang, D., Ye, D., Zou, L., Shen, Y., Dai, L. & Xu, J., 2014, In : Biochemical and Biophysical Research Communications. 449, 4, p. 466-470

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Neurotrophin-3 Induces BMP-2 and VEGF Activities and Promotes the Bony Repair of Injured Growth Plate Cartilage and Bone in Rats

Su, Y., Chung, R., Ruan, C., Chim, S., Kuek, V., Dwivedi, P., Hassanshahi, M., Chen, K., Xie, Y., Chen, L., Foster, B., Rosen, V., Zhou, X., Xu, J. & Xian, C., Jun 2016, In : Journal of Bone & Mineral Research. 31, 6, p. 1258-1274

Research output: Contribution to journalArticle

24 Citations (Scopus)
2015

Non-severe burn injury leads to depletion of bone volume that can be ameliorated by inhibiting TNF-α

O'Halloran, E., Kular, J., Xu, J., Wood, F. & Fear, M., May 2015, In : Burns. 41, 3, p. 558-564

Research output: Contribution to journalArticle

12 Citations (Scopus)
2019

Connecting Versatile lncRNAs with Heterogeneous Nuclear Ribonucleoprotein K and Pathogenic Disorders

Zhu, S., Wang, Z. & Xu, J., 1 Sep 2019, In : Trends in Biochemical Sciences. 44, 9, p. 733-736 4 p.

Research output: Contribution to journalShort survey

1 Citation (Scopus)
2018

Roles of neurotrophins in skeletal tissue formation and healing

Su, Y. W., Zhou, X. F., Foster, B. K., Grills, B. L., Xu, J. & Xian, C. J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2133-2145 13 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
2019

Tiliroside is a new potential therapeutic drug for osteoporosis in mice

Li, K., Xiao, Y., Wang, Z., Fu, F., Shao, S., Song, F., Zhao, J., Lin, X., Liu, Q. & Xu, J., 1 Sep 2019, In : Journal of Cellular Physiology. 234, 9, p. 16263-16274 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Differential protein expression between normal and degenerated human nucleus pulposus cells by proteomic and bioinformatics analyses

Ye, D. P., Liang, W. G., Dai, L., Yao, Y., Chen, H., Zhou, Y. & Xu, J., 2017, In : International Journal of Clinical and Experimental Medicine. 10, 12, p. 16172-16180 9 p.

Research output: Contribution to journalArticle

Open Access
File
57 Downloads (Pure)

Injectable supramolecular hydrogel formed from α-cyclodextrin and PEGylated arginine-functionalized poly(L-lysine) dendron for sustained MMP-9 shRNA plasmid delivery

Lin, Q., Yang, Y., Hu, Q., Guo, Z., Liu, T., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Feb 2017, In : Acta Biomaterialia. 49, p. 456-471 16 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2019

Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease

Zhu, S., Qiu, H., Bennett, S., Kuek, V., Rosen, V., Xu, H. & Xu, J., Nov 2019, In : Cellular and Molecular Life Sciences. 76, 22, p. 4493-4502

Research output: Contribution to journalReview article

Open Access
2016

The y6 receptor suppresses bone resorption and stimulates bone formation in mice via a suprachiasmatic nucleus relay

Khor, E. C., Yulyaningsih, E., Driessler, F., Kovaĉić, N., Wee, N. K. Y., Kulkarni, R. N., Lee, N. J., Enriquez, R. F., Xu, J., Zhang, L., Herzog, H. & Baldock, P. A., Mar 2016, In : Bone. 84, p. 139-147 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2018

Synthesis of Janus Au nanorods/polydivinylbenzene hybrid nanoparticles for chemo-photothermal therapy

Wang, Y., Ji, X., Pang, P., Shi, Y., Dai, J., Xu, J., Wu, J., Kirk, T. B. & Xue, W., 28 Apr 2018, In : Journal of Materials Chemistry B. 6, 16, p. 2481-2488 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2019

Emerging Trend in the Pharmacotherapy of Osteoarthritis

Zhang, W., Robertson, W. B., Zhao, J., Chen, W. & Xu, J., 2 Jul 2019, In : Frontiers in Endocrinology. 10, 9 p., 431.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)
2016

Folate-targeting redox hyperbranched poly(amido amine)s delivering MMP-9 siRNA for cancer therapy

Li, M., Zhou, X., Zeng, X., Wang, C., Xu, J., Ma, D. & Xue, W., 2016, In : Journal of Materials Chemistry B. 4, 3, p. 547-556

Research output: Contribution to journalArticle

32 Citations (Scopus)
2013

Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPαlpha promoter methylation

Li, J., Zhang, N., Huang, X., Xu, J., Fernandes, J. C., Dai, K. & Zhang, X., 2013, In : Cell Death & Disease. 4, p. 11pp

Research output: Contribution to journalArticle

Open Access
80 Citations (Scopus)
2015

Predicting selective liver X receptor β agonists using multiple machine learning methods

Li, Y., Wang, L., Liu, Z., Li, C., Xu, J., Gu, Q. & Xu, J., 1 May 2015, In : Molecular Biosystems. 11, 5, p. 1241-1250

Research output: Contribution to journalArticle

15 Citations (Scopus)
2019

Double network shape memory hydrogels activated by near-infrared with high mechanical toughness, nontoxicity, and 3D printability

Dai, W., Guo, H., Gao, B., Ruan, M., Xu, L., Wu, J., Kirk, T. B., Xu, J., Ma, D. & Xue, W., 15 Jan 2019, In : Chemical Engineering Journal. 356, p. 934-949 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2013

New Bone Formation and Microstructure Assessed by Combination of Confocal Laser Scanning Microscopy and Differential Interference Contrast Microscopy

Yang, X., Qin, L., Liang, W., Wang, W., Tan, J., Liang, P., Xu, J., Li, S. & Cui, S., 2013, In : Calcified Tissue International. 94, p. 338-347

Research output: Contribution to journalArticle

5 Citations (Scopus)
2018

Green synthesis of lignin nanoparticle in aqueous hydrotropic solution toward broadening the window for its processing and application

Chen, L., Zhou, X., Shi, Y., Gao, B., Wu, J., Kirk, T. B., Xu, J. & Xue, W., 15 Aug 2018, In : Chemical Engineering Journal. 346, p. 217-225 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2019

Cumambrin A prevents OVX-induced osteoporosis via the inhibition of osteoclastogenesis, bone resorption, and RANKL signaling pathways

Zhou, L., Liu, Q., Hong, G., Song, F., Zhao, J., Yuan, J., Xu, J., Tan, R. X., Tickner, J., Gu, Q. & Xu, J., 1 Jun 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 6, p. 6726-6735 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2013

SC-514, a selective inhibitor of IKKβ attenuates RANKL-induced osteoclastogenesis and NF-κB activation

Liu, Q., Wu, H., Chim, S., Zhou, L., Zhao, J., Feng, H., Wei, Q., Wang, Q., Zheng, M., Tan, R. X., Gu, Q., Xu, J., Pavlos, N., Tickner, J. & Xu, J., 2013, In : Biochemical Pharmacology. 86, 12, p. 1775-1783

Research output: Contribution to journalArticle

30 Citations (Scopus)
2017

Mechanical Stress Regulates Bone Metabolism Through MicroRNAs

Yuan, Y., Zhang, L., Tong, X., Zhang, M., Zhao, Y., Guo, J., Lei, L., Chen, X., Tickner, J., Xu, J. & Zou, J., 1 Jun 2017, In : Journal of Cellular Physiology. 232, 6, p. 1239-1245 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2016

Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation

Liu, Q., Wang, T., Zhou, L., Song, F., Qin, A., Feng, H. T., Lin, X. X., Lin, Z., Yuan, J. B., Tickner, J., Liu, H. G., Zheng, M. H., Xu, J. & Zhao, J. M., 8 Nov 2016, In : Scientific Reports. 6, p. 1-10 36662 .

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)
2017

The Emerging Role of MORC Family Proteins in Cancer Development and Bone Homeostasis

Hong, G., Qiu, H., Wang, C., Jadhav, G., Wang, H., Tickner, J., He, W. & Xu, J., 1 May 2017, In : Journal of Cellular Physiology. 232, 5, p. 928-934 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts

Liu, J., Dang, L., Li, D., Liang, C., He, X., Wu, H., Qian, A., Yang, Z., Au, D. W. T., Chiang, M. W. L., Zhang, B. T., Han, Q., Yue, K. K. M., Zhang, H., Lv, C., Pan, X., Xu, J., Bian, Z., Shang, P., Tan, W. & 4 others, Liang, Z., Guo, B., Lu, A. & Zhang, G., 2015, In : Biomaterials. 52, 1, p. 148-160

Research output: Contribution to journalArticle

38 Citations (Scopus)
2013

HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors

Van Der Kraan, A. G. J., Chai, R. C. C., Singh, P. P., Lang, B. J., Xu, J., Gillespie, M. T., Price, J. T. & Quinn, J. M. W., 2013, In : Biochemical Journal. 451, 2, p. 235-244

Research output: Contribution to journalArticle

37 Citations (Scopus)
2019

PIP5k1 beta controls bone homeostasis through modulating both osteoclast and osteoblast differentiation

Zhao, X., Cui, P., Wang, C., Zhao, J., Zhang, X. & Xu, J., Dec 2019, In : Journal of Bone and Mineral Research. 34, p. 328-328 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2015

Choline kinase β mutant mice exhibit reduced phosphocholine, elevated osteoclast activity, and low bone mass

Kular, J., Tickner, J., Pavlos, N., Viola, H., Abel, T., Lim, B., Yang, X., Chen, H., Cook, R., Hool, L., Zheng, M. & Xu, J., 16 Jan 2015, In : Journal of Biological Chemistry. 290, 3, p. 1729-1742

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)
2019

Sclareol prevents ovariectomy-induced bone loss: In vivo and inhibits osteoclastogenesis in vitro via suppressing NF-κB and MAPK/ERK signaling pathways

Jin, H., Shao, Z., Wang, Q., Miao, J., Bai, X., Liu, Q., Qiu, H., Wang, C., Zhang, Z., Jennifer, T., Wang, X. & Xu, J., 1 Oct 2019, In : Food and Function. 10, 10, p. 6556-6567 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2011

EGFL6 promotes endothelial cell migration and angiogenesis through the activation of Extracellular Signal-regulated Kinase

Chim, S., Qin, A., Tickner, J., Pavlos, N., Davey, T. N., Wang, H., Guo, Y., Zheng, M. & Xu, J., 2011, In : Journal of Biological Chemistry. 286, 25, p. 22035-22046

Research output: Contribution to journalArticle

55 Citations (Scopus)
2019

MiR-214 is an important regulator of the musculoskeletal metabolism and disease

Sun, Y., Kuek, V., Liu, Y., Tickner, J., Yuan, Y., Chen, L., Zeng, Z., Shao, M., He, W. & Xu, J., Jan 2019, In : Journal of Cellular Physiology. 234, 1, p. 231-245 15 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Dehydrocostus lactone (DHC) suppresses estrogen deficiency-induced osteoporosis

Li, Z., Yuan, G., Lin, X., Liu, Q., Xu, J., Lian, Z., Song, F., Zheng, J., Xie, D., Chen, L., Wang, X., Feng, H., Zhou, M. & Yao, G., 1 May 2019, In : Biochemical Pharmacology. 163, p. 279-289 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Calmodulin interacts with Rab3D and modulates osteoclastic bone resorption

Zhu, S., Chim, S. M., Cheng, T., Ang, E., Ng, B., Lim, B., Chen, K., Qiu, H., Tickner, J., Xu, H., Pavlos, N. & Xu, J., 29 Nov 2016, In : Scientific Reports. 6, p. 1-9

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
2019

Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

Liu, Y., Wang, C., Wang, G., Sun, Y., Deng, Z., Chen, L., Chen, K., Tickner, J., Kenny, J., Song, D., Zhang, Q., Wang, H., Chen, Z., Zhou, C., He, W. & Xu, J., 2019, In : Theranostics. 9, 16, p. 4648-4662 15 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis

Jin, H., Wang, Q., Chen, K., Xu, K., Pan, H., Chu, F., Ye, Z., Wang, Z., Tickner, J., Qiu, H., Wang, C., Kenny, J., Xu, H., Wang, T. & Xu, J., 1 Dec 2019, In : Journal of Cellular and Molecular Medicine. 23, 12, p. 8355-8368 14 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2015

Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-қB activation and titanium particle-induced osteolysis in a mouse model

Huang, J., Zhou, L., Wu, H., Pavlos, N., Chim, S., Liu, Q., Zhao, J., Xue, W., Tan, R., Ye, J., Ang, E., Feng, H. T., Tickner, J., Xu, J., Ding, Y. & Xu, J., 5 Jan 2015, In : Molecular and Cellular Endocrinology. 399, p. 346-353

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
377 Downloads (Pure)
2020

Fumitremorgin C Attenuates Osteoclast Formation and Function via Suppressing RANKL-Induced Signaling Pathways

Yuan, Y., Chen, K., Chen, X., Wang, C., Qiu, H., Cao, Z., Song, D., Sun, Y., Guo, J., Tickner, J., Xu, J. & Zou, J., 10 Mar 2020, In : Frontiers in Pharmacology. 11, 238.

Research output: Contribution to journalArticle

Open Access

Coupling factors and exosomal packaging microRNAs involved in the regulation of bone remodelling

Zhu, S., Yao, F., Qiu, H., Zhang, G., Xu, H. & Xu, J., Feb 2018, In : Biological Reviews. 93, 1, p. 469-480 12 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
456 Downloads (Pure)
2015

Comparative and quantitative proteomic analysis of normal and degenerated human annulus fibrosus cells

Ye, D., Liang, W., Dai, L., Zhou, L., Yao, Y., Zhong, X., Chen, H. & Xu, J., 2015, In : Clinical and Experimental Pharmacology and Physiology. 42, 5, p. 530-536

Research output: Contribution to journalArticle

9 Citations (Scopus)