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2012

The role of renal nerves in cardiorenal syndrome in heart failure

Katholi, R., Sobotka, P. A., Schlaich, M. & Krum, H., 2012, The Cardiorenal Syndrome: A Clinician’s Guide to Pathophsyiology and Management. Heywood, J. T. & Burnett Jr, J. C. (eds.). Cardiotext Publishing

Research output: Chapter in Book/Conference paperChapter

2015

Renal denervation: Potential future implications beyond resistant hypertension

Schlaich, M. P., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. New York: Springer-Verlag London Ltd., p. 155-161 7 p.

Research output: Chapter in Book/Conference paperChapter

Sympathetic Nervous System
Denervation
Hypertension
Kidney
Sympatholytics
2013
95 Citations (Scopus)

Feasibility of catheter-based renal nerve ablation and effects on sympathetic nerve activity and blood pressure in patients with end-stage renal disease

Schlaich, M. P., Bart, B., Hering, D., Walton, A., Marusic, P., Mahfoud, F., Böhm, M., Lambert, E. A., Krum, H., Sobotka, P. A., Schmieder, R. E., Ika-Sari, C., Eikelis, N., Straznicky, N., Lambert, G. W. & Esler, M. D., 3 Oct 2013, In : International Journal of Cardiology. 168, 3, p. 2214-2220 7 p.

Research output: Contribution to journalArticle

Chronic Kidney Failure
Catheters
Blood Pressure
Kidney
Denervation
2014
25 Citations (Scopus)

Critical issues in patient selection, efficacy, and safety of renal denervation

Schlaich, M. P., Esler, M. D., Fink, G. D., Osborn, J. W. & Euler, D. E., Mar 2014, In : Hypertension. 63, 3, p. 426-432 7 p.

Research output: Contribution to journalReview article

Open Access
2018

Reply to letter to the Editor entitled: Ambulatory arterial stiffness index: a (too) easy predictor for renal denervation success?

Sata, Y., Head, G. A., Esler, M. D. & Schlaich, M. P., 1 Jul 2018, In : Journal of Hypertension. 36, 7, p. 1606-1607 2 p.

Research output: Contribution to journalLetter

2013
1 Citation (Scopus)
2010
71 Citations (Scopus)

Association between the sympathetic firing pattern and anxiety level in patients with the metabolic syndrome and elevated blood pressure

Lambert, E., Dawood, T., Straznicky, N., Sari, C., Schlaich, M., Esler, M. & Lambert, G., Mar 2010, In : Journal of Hypertension. 28, 3, p. 543-550 8 p.

Research output: Contribution to journalArticle

Metabolome
Anxiety
Sympathetic Nervous System
Depression
Blood Pressure
2018
4 Citations (Scopus)

A polymorphism in the noradrenaline transporter gene is associated with increased blood pressure in patients with resistant hypertension

Eikelis, N., Marques, F. Z., Hering, D., Marusic, P., Head, G. A., Walton, A. S., Lambert, E. A., Esler, M. D., Sari, C. I., Schlaich, M. P. & Lambert, G. W., 1 Jul 2018, In : Journal of Hypertension. 36, 7, p. 1571-1577 7 p.

Research output: Contribution to journalArticle

Norepinephrine Plasma Membrane Transport Proteins
Norepinephrine
Blood Pressure
Hypertension
Genes
2012
21 Citations (Scopus)

Laparoscopic adjustable gastric banding and other devices for the management of obesity

Dixon, J. B., Straznicky, N. E., Lambert, E. A., Schlaich, M. P. & Lambert, G. W., 7 Aug 2012, In : Circulation. 126, 6, p. 774-785 12 p.

Research output: Contribution to journalArticle

Open Access
2013
25 Citations (Scopus)

Chronic kidney disease: Role of sympathetic nervous system activation and potential benefits of renal denervation

Hering, D., Esler, M. D. & Schlaich, M. P., 2013, In : EuroIntervention. 9, p. R127-R135

Research output: Contribution to journalArticle

Sympathetic Nervous System
Denervation
Chronic Renal Insufficiency
Kidney
Chronic Kidney Failure
2014
14 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Blood pressure
Immune system
Blood Pressure
Plasmas
2016
4 Citations (Scopus)

Three-year changes of prothrombotic factors in a cohort of South Africans with a high clinical suspicion of obstructive sleep apnea

Von Känel, R., Malan, N. T., Hamer, M., Lambert, G. W., Schlaich, M., Reimann, M. & Malan, L., 2016, In : Thrombosis and Haemostasis. 115, 1, p. 63-72

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Urokinase Plasminogen Activator Receptors
von Willebrand Factor
Fibrin Clot Lysis Time
Fibrinogen
2010

Controlling Blood Pressure without Drugs – Developing New Strategies

Schlaich, M. & Esler, M. D., 2010, In : European Cardiology. 6, 2, p. 18-21

Research output: Contribution to journalReview article

2019
15 Citations (Scopus)

Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry

Mahfoud, F., Böhm, M., Schmieder, R., Narkiewicz, K., Ewen, S., Ruilope, L., Schlaich, M., Williams, B., Fahy, M. & Mancia, G., 1 Nov 2019, In : European Heart Journal. 40, 42, p. 3474-3482 9 p.

Research output: Contribution to journalArticle

Open Access
Denervation
Registries
Kidney
Blood Pressure
Safety
2012
23 Citations (Scopus)

Greater cardiovascular reactivity to a cold stimulus is due to higher cold pain perception in black Africans: The Sympathetic Activity and Ambulatory Blood Pressure in Africans (SABPA) study

Reimann, M., Hamer, M., Schlaich, M. P., Malan, N. T., Ruediger, H., Ziemssen, T. & Malan, L., Dec 2012, In : Journal of Hypertension. 30, 12, p. 2416-2424 9 p.

Research output: Contribution to journalArticle

Pain Perception
Blood Pressure
Baroreflex
Pain
Hypertension
2013
52 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

Denervation
Hypertension
Kidney
Blood Pressure
Muscles
2010
133 Citations (Scopus)

Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults

Lambert, E., Sari, C. I., Dawood, T., Nguyen, J., McGrane, M., Eikelis, N., Chopra, R., Wong, C., Chatzivlastou, K., Head, G., Straznicky, N., Esler, M., Schlaich, M. & Lambert, G., 1 Sep 2010, In : Hypertension. 56, 3, p. 351-358 8 p.

Research output: Contribution to journalArticle

Open Access
Sympathetic Nervous System
Young Adult
Obesity
Muscles
Kidney
2017
16 Citations (Scopus)

A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism

Marques, F. Z., Eikelis, N., Bayles, R. G., Lambert, E. A., Straznicky, N. E., Hering, D., Esler, M. D., Head, G. A., Barton, D. A., Schlaich, M. P. & Lambert, G. W., 1 Jan 2017, In : Molecular Psychiatry. 22, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

Norepinephrine Plasma Membrane Transport Proteins
MicroRNAs
Cardiovascular Diseases
Postural Orthostatic Tachycardia Syndrome
Genes
2015
48 Citations (Scopus)

New developments in the pathogenesis of obesity-induced hypertension

Kotsis, V., Nilsson, P., Grassi, G., Mancia, G., Redon, J., Luft, F., Schmieder, R., Engeli, S., Stabouli, S., Antza, C., Pall, D., Schlaich, M. & Jordan, J., 2015, In : Journal of Hypertension. 33, 8, p. 1499-1508

Research output: Contribution to journalArticle

Obesity
Hypertension
Melanocyte-Stimulating Hormones
Leptin Receptors
Gene-Environment Interaction
116 Citations (Scopus)

First report of the global SYMPLICITY registry on the effect of renal artery denervation in patients with uncontrolled hypertension

Böhm, M., Mahfoud, F., Ukena, C., Hoppe, U. C., Narkiewicz, K., Negoita, M., Ruilope, L., Schlaich, M., Schmieder, R. E., Whitbourn, R., Williams, B., Zeymer, U., Zirlik, A. & Mancia, G., 2015, In : Hypertension. 65, 4, p. 766-774

Research output: Contribution to journalArticle

Denervation
Renal Artery
Registries
Blood Pressure
Hypertension
2017
6 Citations (Scopus)

Serum uric acid and the relationship with subclinical organ damage in adults

Lambert, E. A., Hachem, M., Hemmes, R., Straznicky, N. E., Eikelis, N., Sari, C. I., Schlaich, M. P., Lambert, G. W. & Dixon, J. B., 1 Apr 2017, In : Journal of Hypertension. 35, 4, p. 745-752 8 p.

Research output: Contribution to journalArticle

Uric Acid
Serum
Metabolome
Glomerular Filtration Rate
Waist Circumference
2014
156 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
Denervation
Catheters
Randomized Controlled Trials
Blood Pressure
Hypertension
2013
240 Citations (Scopus)

Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Walton, A. S., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Feb 2013, In : Hypertension. 61, 2, p. 457-464 8 p.

Research output: Contribution to journalArticle

Open Access
Denervation
Hypertension
Kidney
Blood Pressure
Muscles
2015
9 Citations (Scopus)

Device-based approaches for renal nerve ablation for hypertension and beyond

Thorp, A. A. & Schlaich, M., 8 Jul 2015, In : Frontiers in Physiology. 6, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
Hypertension
Kidney
Equipment and Supplies
Denervation
Blood Pressure
2010
10 Citations (Scopus)

New therapeutic approaches to resistant hypertension

Schlaich, M. P., Krum, H. & Esler, M. D., Aug 2010, In : Current Hypertension Reports. 12, 4, p. 296-302 7 p.

Research output: Contribution to journalReview article

Hypertension
Blood Pressure
Antihypertensive Agents
Therapeutics
Equipment and Supplies
2014

Response to more research is needed to investigate the effect of denervation on blood pressure

Schlaich, M., Esler, M., Fink, G., Osborn, J. & Euler, D., Apr 2014, In : Hypertension. 63, 4

Research output: Contribution to journalLetter

Open Access
2015
37 Citations (Scopus)

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering

Mclellan, A. J. A., Schlaich, M., Taylor, A. J., Prabhu, S. G. S., Hering, D., Hammond, L., Marusic, P., Duval, J., Sata, Y., Ellims, A. H., Esler, M. D., Peter, K., Shaw, J. A., Walton, A. S., Kalman, J. M. & Kistler, P. M., 1 May 2015, In : Heart Rhythm. 12, 5, p. 982-990

Research output: Contribution to journalArticle

Denervation
Blood Pressure
Kidney
Hypertension
Magnetic Resonance Imaging
2016
2 Citations (Scopus)

Residual sympathetic responsiveness after catheter-based renal denervation: Lessons from renal nerve stimulation

Schlaich, M. P., Sata, Y. & Hering, D., 2016, In : Hypertension. 67, 6, p. 1117-1118 2 p.

Research output: Contribution to journalLetter

2017
4 Citations (Scopus)
174 Downloads (Pure)

Neck circumference is associated with muscle sympathetic nerve activity in overweight and obese men but not women

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P., Phillips, S. E. & Lambert, E. A., 6 Apr 2017, In : Frontiers in Physiology. 8, APR, 203.

Research output: Contribution to journalArticle

Open Access
File
Neck
Muscles
Insulin
Insulin Resistance
Fasting
2014
91 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
Denervation
Left Ventricular Function
Magnetic Resonance Imaging
Hypertension
Kidney
2018
5 Citations (Scopus)

Renal DenervationReady for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M. P., Kiuchi, M. G. & Esler, M. D., Aug 2018, In : Hypertension. 72, 2, p. 287-290 4 p.

Research output: Contribution to journalEditorial

2012
97 Citations (Scopus)

Ambulatory blood pressure monitoring in Australia: 2011 consensus position statement

Head, G. A., McGrath, B. P., Mihailidou, A. S., Nelson, M. R., Schlaich, M. P., Stowasser, M., Mangoni, A. A., Cowley, D., Brown, M. A., Ruta, L. A. & Wilson, A., Feb 2012, In : Journal of Hypertension. 30, 2, p. 253-266 14 p.

Research output: Contribution to journalArticle

Ambulatory Blood Pressure Monitoring
Ambulatory Monitoring
Blood Pressure
Hypertension
Cardiovascular Diseases
2014
11 Citations (Scopus)

Regulation of the sympathetic nervous system by the kidney

Larsen, R., Thorp, A. & Schlaich, M., 2014, In : Current Opinion in Nephrology and Hypertension. 23, 1, p. 61-68 8 p.

Research output: Contribution to journalReview article

Sympathetic Nervous System
Kidney
Hypertension
Denervation
Pressoreceptors
2013
19 Citations (Scopus)
Open Access
moxonidine
Imidazolines
Blood Pressure
Hypertension
Population
2017
2 Citations (Scopus)

The metalloproteinase ADAM28 promotes metabolic dysfunction in mice

Herat, L., Rudnicka, C., Okada, Y., Mochizuki, S., Schlaich, M. & Matthews, V., 21 Apr 2017, In : International Journal of Molecular Sciences. 18, 4, 12 p., 884.

Research output: Contribution to journalArticle

Open Access
obesity
Disintegrins
Metalloproteases
mice
aspartates
2014
1 Citation (Scopus)

Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: The SABPA Study

Malan, N. T., Stalder, T., Schlaich, M. P., Lambert, G. W., Hamer, M., Schutte, A. E., Huisman, H. W., Schutte, R., Smith, W., Mels, C. M. C., Van Rooyen, J. M. & Malan, L., Jun 2014, In : Journal of Human Hypertension. 28, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

Hypotension
Blood Vessels
Hydrocortisone
Testosterone
Blood Pressure

Rebuttal from Markus P. Schlaich, Yusuke Sata and Murray D. Esler

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2013
4 Citations (Scopus)

Renal sympathetic nerve ablation for the management of resistant hypertension: An update

Thorp, A. A., Larsen, R. N. & Schlaich, M. P., Nov 2013, In : Current Opinion in Nephrology and Hypertension. 22, 6, p. 607-614 8 p.

Research output: Contribution to journalReview article

Hypertension
Kidney
Blood Pressure
Clinical Trials
Safety
2014

Baroreflex sensitivity: A reliable predictor of response to renal denervation?

Hering, D., Esler, M. D. & Schlaich, M. P., 15 Jul 2014, In : Journal of the American College of Cardiology. 64, 2, p. 232-233 2 p.

Research output: Contribution to journalLetter

Open Access
2013
34 Citations (Scopus)

Defensive coping facilitates higher blood pressure and early sub-clinical structural vascular disease via alterations in heart rate variability: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G., Ziemssen, T., Reimann, M., Frasure-Smith, N., Amirkhan, J. H., Schutte, R., van Rooyen, J. M., Mels, C. M., Fourie, C. M. T., Uys, A. S. & Malan, N. T., 1 Apr 2013, In : Atherosclerosis. 227, 2, p. 391-397 7 p.

Research output: Contribution to journalArticle

Vascular Diseases
Heart Rate
Hypertension
Carotid Intima-Media Thickness
Autonomic Nervous System
2018
2 Citations (Scopus)

Renal denervation: one step backwards, three steps forward

Schlaich, M. P. & Bakris, G. L., Oct 2018, In : Nature Reviews Nephrology. 14, 10, p. 602-604 2 p.

Research output: Contribution to journalEditorial

Denervation
Blood Pressure
Hypertension
Kidney
Therapeutics
2015
16 Citations (Scopus)
189 Downloads (Pure)

The Role of Central Nervous System Mechanisms in Resistant Hypertension

Hering, D. & Schlaich, M., Aug 2015, In : Current Hypertension Reports. 17, 58, p. 1-9

Research output: Contribution to journalReview article

Open Access
File
Central Nervous System
Hypertension
Blood Pressure
Morbidity
Mortality
2014
14 Citations (Scopus)

The effects of dietary weight loss on indices of norepinephrine turnover: Modulatory influence of hyperinsulinemia

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Richards, K., Nestel, P. J., Dawood, T., Masuo, K., Sari, C. I., Dixon, J. B., Esler, M. D., Paul, E., Schlaich, M. P. & Lambert, G. W., 2014, In : Obesity. 22, 3, p. 652-662 11 p.

Research output: Contribution to journalArticle

Hyperinsulinism
Weight Loss
Norepinephrine
Dihydroxyphenylalanine
Down-Regulation
2016
8 Citations (Scopus)

Is it time to think about the sodium glucose co-transporter 2 sympathetically?

Elliott, R. H., Matthews, V. B., Rudnicka, C. & Schlaich, M. P., 2016, In : Nephrology. 21, 4, p. 286-294 9 p.

Research output: Contribution to journalReview article

Sodium-Glucose Transporter 2
Symporters
Glucose
Type 2 Diabetes Mellitus
Sympathetic Nervous System
2014
22 Citations (Scopus)

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K. C., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N. E., Kingwell, B. A. & De Courten, B., 1 Feb 2014, In : Amino Acids. 46, 2, p. 321-326 6 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Glucose Tolerance Test
Healthy Volunteers
Insulin
Glucose
2010
78 Citations (Scopus)

The role of sympathetic nervous activity in renal injury and end-stage renal disease

Masuo, K., Lambert, G. W., Esler, M. D., Rakugi, H., Ogihara, T. & Schlaich, M. P., Jun 2010, In : Hypertension Research. 33, 6, p. 521-528 8 p.

Research output: Contribution to journalReview article

Open Access
Chronic Kidney Failure
Kidney
Wounds and Injuries
Hypertension
Obesity
2014
16 Citations (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

Denervation
Sympathetic Nervous System
Kidney
Hypertension
Sympatholytics
2016
6 Citations (Scopus)
Sympathectomy
Chronic Kidney Failure
Catheters
Kidney
Denervation
15 Citations (Scopus)

Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: The SABPA study

Malan, L., Hamer, M., Von Känel, R., Schlaich, M., Reimann, M., Frasure-Smith, N., Lambert, G. W., Vilser, W., Harvey, B. H., Steyn, F. & Malan, N. T., 2016, In : Nitric Oxide - Biology and Chemistry. 55-56, p. 10-17

Research output: Contribution to journalArticle

Open Access
Retinal Vessels
Nitric Oxide
Blood Vessels
Light
Perfusion
2010
61 Citations (Scopus)

Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves

Hennebry, S. C., Eikelis, N., Socratous, F., Desir, G., Lambert, G. & Schlaich, M., Mar 2010, In : Molecular Psychiatry. 15, 3, p. 234-236 3 p.

Research output: Contribution to journalLetter

Open Access