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2012

The role of renal nerves in cardiorenal syndrome in heart failure

Katholi, R., Sobotka, P. A., Schlaich, M. & Krum, H., 2012, The Cardiorenal Syndrome: A Clinician’s Guide to Pathophsyiology and Management. Heywood, J. T. & Burnett Jr, J. C. (eds.). Cardiotext Publishing

Research output: Chapter in Book/Conference paperChapter

2013
52 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

Denervation
Hypertension
Kidney
Blood Pressure
Muscles
2010
133 Citations (Scopus)

Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults

Lambert, E., Sari, C. I., Dawood, T., Nguyen, J., McGrane, M., Eikelis, N., Chopra, R., Wong, C., Chatzivlastou, K., Head, G., Straznicky, N., Esler, M., Schlaich, M. & Lambert, G., 1 Sep 2010, In : Hypertension. 56, 3, p. 351-358 8 p.

Research output: Contribution to journalArticle

Open Access
Sympathetic Nervous System
Young Adult
Obesity
Muscles
Kidney
10 Citations (Scopus)

New therapeutic approaches to resistant hypertension

Schlaich, M. P., Krum, H. & Esler, M. D., Aug 2010, In : Current Hypertension Reports. 12, 4, p. 296-302 7 p.

Research output: Contribution to journalReview article

Hypertension
Blood Pressure
Antihypertensive Agents
Therapeutics
Equipment and Supplies
2014

Response to more research is needed to investigate the effect of denervation on blood pressure

Schlaich, M., Esler, M., Fink, G., Osborn, J. & Euler, D., Apr 2014, In : Hypertension. 63, 4

Research output: Contribution to journalLetter

Open Access
2016
2 Citations (Scopus)

Residual sympathetic responsiveness after catheter-based renal denervation: Lessons from renal nerve stimulation

Schlaich, M. P., Sata, Y. & Hering, D., 2016, In : Hypertension. 67, 6, p. 1117-1118 2 p.

Research output: Contribution to journalLetter

2014
91 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
Denervation
Left Ventricular Function
Magnetic Resonance Imaging
Hypertension
Kidney
11 Citations (Scopus)

Regulation of the sympathetic nervous system by the kidney

Larsen, R., Thorp, A. & Schlaich, M., 2014, In : Current Opinion in Nephrology and Hypertension. 23, 1, p. 61-68 8 p.

Research output: Contribution to journalReview article

Sympathetic Nervous System
Kidney
Hypertension
Denervation
Pressoreceptors
2013
19 Citations (Scopus)
Open Access
moxonidine
Imidazolines
Blood Pressure
Hypertension
Population
2017
2 Citations (Scopus)

The metalloproteinase ADAM28 promotes metabolic dysfunction in mice

Herat, L., Rudnicka, C., Okada, Y., Mochizuki, S., Schlaich, M. & Matthews, V., 21 Apr 2017, In : International Journal of Molecular Sciences. 18, 4, 12 p., 884.

Research output: Contribution to journalArticle

Open Access
obesity
Disintegrins
Metalloproteases
mice
aspartates
2014

Baroreflex sensitivity: A reliable predictor of response to renal denervation?

Hering, D., Esler, M. D. & Schlaich, M. P., 15 Jul 2014, In : Journal of the American College of Cardiology. 64, 2, p. 232-233 2 p.

Research output: Contribution to journalLetter

Open Access
2011
46 Citations (Scopus)

Renal denervation and hypertension

Schlaich, M. P., Krum, H., Sobotka, P. A. & Esler, M. D., Jun 2011, In : American Journal of Hypertension. 24, 6, p. 635-642 8 p.

Research output: Contribution to journalArticle

Open Access
Renal Hypertension
Denervation
Kidney
Blood Pressure
Hypertension
2013
34 Citations (Scopus)

Defensive coping facilitates higher blood pressure and early sub-clinical structural vascular disease via alterations in heart rate variability: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G., Ziemssen, T., Reimann, M., Frasure-Smith, N., Amirkhan, J. H., Schutte, R., van Rooyen, J. M., Mels, C. M., Fourie, C. M. T., Uys, A. S. & Malan, N. T., 1 Apr 2013, In : Atherosclerosis. 227, 2, p. 391-397 7 p.

Research output: Contribution to journalArticle

Vascular Diseases
Heart Rate
Hypertension
Carotid Intima-Media Thickness
Autonomic Nervous System
2016
8 Citations (Scopus)

Is it time to think about the sodium glucose co-transporter 2 sympathetically?

Elliott, R. H., Matthews, V. B., Rudnicka, C. & Schlaich, M. P., 2016, In : Nephrology. 21, 4, p. 286-294 9 p.

Research output: Contribution to journalReview article

Sodium-Glucose Transporter 2
Symporters
Glucose
Type 2 Diabetes Mellitus
Sympathetic Nervous System
2014
22 Citations (Scopus)

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K. C., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N. E., Kingwell, B. A. & De Courten, B., 1 Feb 2014, In : Amino Acids. 46, 2, p. 321-326 6 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Glucose Tolerance Test
Healthy Volunteers
Insulin
Glucose
16 Citations (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

Denervation
Sympathetic Nervous System
Kidney
Hypertension
Sympatholytics
2016
6 Citations (Scopus)
Sympathectomy
Chronic Kidney Failure
Catheters
Kidney
Denervation
2011
27 Citations (Scopus)

Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P., Hilgers, K. F. & Schmieder, R. E., Jun 2011, In : Pharmacogenetics and Genomics. 21, 6, p. 347-349 3 p.

Research output: Contribution to journalArticle

Renin
Blood Pressure
Genes
Alleles
Renin-Angiotensin System
2016
15 Citations (Scopus)

Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: The SABPA study

Malan, L., Hamer, M., Von Känel, R., Schlaich, M., Reimann, M., Frasure-Smith, N., Lambert, G. W., Vilser, W., Harvey, B. H., Steyn, F. & Malan, N. T., 2016, In : Nitric Oxide - Biology and Chemistry. 55-56, p. 10-17

Research output: Contribution to journalArticle

Open Access
Retinal Vessels
Nitric Oxide
Blood Vessels
Light
Perfusion
2010
61 Citations (Scopus)

Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves

Hennebry, S. C., Eikelis, N., Socratous, F., Desir, G., Lambert, G. & Schlaich, M., Mar 2010, In : Molecular Psychiatry. 15, 3, p. 234-236 3 p.

Research output: Contribution to journalLetter

Open Access
2017

Renal denervation in less severe forms of (resistant) hypertension—Quo vadis?

Schlaich, M. P., Hering, D. & Sata, Y., 1 Apr 2017, In : Journal of Clinical Hypertension. 19, 4, p. 369-370 2 p.

Research output: Contribution to journalComment/debate

2012
25 Citations (Scopus)

Baseline sympathetic nervous system activity predicts dietary weight loss in obese metabolic syndrome subjects

Straznicky, N. E., Eikelis, N., Nestel, P. J., Dixon, J. B., Dawood, T., Grima, M. T., Sari, C. I., Schlaich, M. P., Esler, M. D., Tilbrook, A. J., Lambert, G. W. & Lambert, E. A., Feb 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 2, p. 605-613 9 p.

Research output: Contribution to journalArticle

Open Access
Sympathetic Nervous System
Neurology
Weight Loss
Muscle
Muscles
2010
10 Citations (Scopus)

Stress reactivity and its association with increased cardiovascular risk: A role for the sympathetic nervous system?

Lambert, G., Schlaich, M., Lambert, E., Dawood, T. & Esler, M., Jun 2010, In : Hypertension. 55, 6

Research output: Contribution to journalLetter

Open Access
2011
24 Citations (Scopus)

Does renalase degrade catecholamines

Eikelis, N., Hennebry, S. C., Lambert, G. W. & Schlaich, M. P., 1 Jun 2011, In : Kidney International. 79, 12, 1 p.

Research output: Contribution to journalLetter

Open Access
2013
1 Citation (Scopus)

Cognitive performance in patients with resistant hypertension following renal sympathetic denervation

Lambert, G. W., Dhar, A. K. & Schlaich, M. P., 1 Oct 2013, In : EuroIntervention. 9, 6, p. 665-667 3 p.

Research output: Contribution to journalEditorial

2012
34 Citations (Scopus)

Renal denervation in human hypertension: Mechanisms, current findings, and future prospects

Schlaich, M. P., Hering, D., Sobotka, P. A., Krum, H. & Esler, M. D., 1 Jun 2012, In : Current Hypertension Reports. 14, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

Denervation
Blood Pressure
Hypertension
Kidney
Left Ventricular Hypertrophy
2014
30 Citations (Scopus)

Morning surge in blood pressure is associated with reactivity of the sympathetic nervous system

Lambert, E. A., Chatzivlastou, K., Schlaich, M., Lambert, G. & Head, G. A., Jun 2014, In : American Journal of Hypertension. 27, 6, p. 783-792 10 p.

Research output: Contribution to journalArticle

Open Access
Sympathetic Nervous System
Blood Pressure
Muscles
Arterial Pressure
Arousal
2016
15 Citations (Scopus)

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

Denervation
Registries
Heart Rate
Hypertension
Kidney
2013
5 Citations (Scopus)

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

Sympathectomy
Hypertension
Kidney
Blood Pressure
Therapeutics
2011
7 Citations (Scopus)

Type 2 diabetes strengthens the association between pulse pressure and chronic kidney disease: The AusDiab study

Van Den Hurk, K., Magliano, D. J., Alssema, M., Schlaich, M. P., Atkins, R. C., Reutens, A. T., Nijpels, G., Dekker, J. M. & Shaw, J. E., May 2011, In : Journal of Hypertension. 29, 5, p. 953-960 8 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Blood Pressure
Glomerular Filtration Rate
Odds Ratio
2012
1 Citation (Scopus)

Catheter based radiofrequency ablation of renal nerves for the treatment of resistant hypertension

Schlaich, M. P., Hering, D. & Esler, M. D., 1 Jun 2012, In : Italian Journal of Medicine. 6, 2, p. 105-109 5 p.

Research output: Contribution to journalArticle

Open Access
Catheter Ablation
Hypertension
Kidney
Blood Pressure
Denervation
2013
4 Citations (Scopus)

Defensive active coping facilitates chronic hyperglycaemia and endothelial dysfunction in African men: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G. W., Ziemssen, T., Reimann, M., Steyn, H. S., Schutte, R., Smith, W., Van Rooyen, J. M., Fourie, C. M. T. & Malan, N. T., 30 Sep 2013, In : International Journal of Cardiology. 168, 2, p. 999-1005 7 p.

Research output: Contribution to journalArticle

Hyperglycemia
Ischemia
ROC Curve
Stroke
Glycosylated Hemoglobin A
2011
461 Citations (Scopus)

Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: A pilot study

Mahfoud, F., Schlaich, M., Kindermann, I., Ukena, C., Cremers, B., Brandt, M. C., Hoppe, U. C., Vonend, O., Rump, L. C., Sobotka, P. A., Krum, H., Esler, M. & Böhm, M., 10 May 2011, In : Circulation. 123, 18, p. 1940-1946 7 p.

Research output: Contribution to journalArticle

Open Access
Sympathectomy
Blood Pressure
Hypertension
Kidney
Glucose
2012
6 Citations (Scopus)

Effects of renal denervation on insulin resistance

Hering, D., Esler, M. D. & Schlaich, M. P., 1 Nov 2012, In : Expert Review of Cardiovascular Therapy. 10, 11, p. 1381-1386 6 p.

Research output: Contribution to journalReview article

Denervation
Insulin Resistance
Hypertension
Kidney
Comorbidity
2014
14 Citations (Scopus)

The effects of dietary weight loss on indices of norepinephrine turnover: Modulatory influence of hyperinsulinemia

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Richards, K., Nestel, P. J., Dawood, T., Masuo, K., Sari, C. I., Dixon, J. B., Esler, M. D., Paul, E., Schlaich, M. P. & Lambert, G. W., 2014, In : Obesity. 22, 3, p. 652-662 11 p.

Research output: Contribution to journalArticle

Hyperinsulinism
Weight Loss
Norepinephrine
Dihydroxyphenylalanine
Down-Regulation
2010
78 Citations (Scopus)

The role of sympathetic nervous activity in renal injury and end-stage renal disease

Masuo, K., Lambert, G. W., Esler, M. D., Rakugi, H., Ogihara, T. & Schlaich, M. P., Jun 2010, In : Hypertension Research. 33, 6, p. 521-528 8 p.

Research output: Contribution to journalReview article

Open Access
Chronic Kidney Failure
Kidney
Wounds and Injuries
Hypertension
Obesity
2016
22 Citations (Scopus)

Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning

Lambert, E. A., Thomas, C. J., Hemmes, R., Eikelis, N., Pathak, A., Schlaich, M. & Lambert, G. W., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 2, p. H364-H370

Research output: Contribution to journalArticle

Ischemic Preconditioning
Reperfusion Injury
Ischemia
Hyperemia
Reperfusion

Renal denervation for resistant hypertension: Closing in on potential confounders

Schlaich, M. P., Schultz, C. & Shetty, S., 2016, In : Journal of Hypertension. 34, 8, p. 1505-1506 2 p.

Research output: Contribution to journalLetter

2010
33 Citations (Scopus)

European Society of Hypertension Working Group on Obesity Antihypertensive effects of weight loss: Myth or reality?

Straznicky, N., Grassi, G., Esler, M., Lambert, G., Dixona, J., Lambert, E., Jordanc, J. & Schlaicha, M., 1 Apr 2010, In : Journal of Hypertension. 28, 4, p. 637-643 7 p.

Research output: Contribution to journalReview article

New Molecules for Treating Resistant Hypertension: a Clinical Perspective

Azzam, O., Kiuchi, M. G., Ho, J. K., Matthews, V. B., Gavidia, L. M. L., Nolde, J. M., Carnagarin, R. & Schlaich, M. P., 1 Oct 2019, In : Current Hypertension Reports. 21, 10, 80.

Research output: Contribution to journalReview article

Hypertension
Spironolactone
Pharmacology
Glutamyl Aminopeptidase
Cytochrome P-450 CYP11B2

Effect of pupil dilation with tropicamide on retinal vascular caliber

Frost, S., Gregory, C., Robinson, L., Yu, S., Xiao, D., Mehdizadeh, M., Burnham, S., Dehghani, C., Vignarajan, J., Kanagasingam, Y., Schlaich, M. P. & Prentice, D., 3 Jul 2019, In : Ophthalmic Epidemiology. 9 p.

Research output: Contribution to journalArticle

Tropicamide
Retinal Vessels
Pupil
Dilatation
Optic Disk
2018
11 Citations (Scopus)

Role of the sympathetic nervous system and its modulation in renal hypertension

Sata, Y., Head, G. A., Denton, K., May, C. N. & Schlaich, M. P., 29 Mar 2018, In : Frontiers in Medicine. 5, March, 82.

Research output: Contribution to journalReview article

Open Access
Renal Hypertension
Sympathetic Nervous System
Kidney
Hypertension
Blood Pressure
2014
1 Citation (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

Denervation
Sympathectomy
Kidney
Blood Pressure
Sympathetic Nervous System
2019
3 Citations (Scopus)

Renal Denervation for Treating Hypertension Current Scientific and Clinical Evidence

Weber, M. A., Mahfoud, F., Schmieder, R. E., Kandzari, D. E., Tsioufis, K. P., Townsend, R. R., Kario, K., Bohm, M., Sharp, A. S. P., Davies, J. E., Osborn, J. W., Fink, G. D., Euler, D. E., Cohen, D. L., Schlaich, M. P. & Esler, M. D., 24 Jun 2019, In : JACC: Cardiovascular Interventions. 12, 12, p. 1095-1105 11 p.

Research output: Contribution to journalReview article

2017
4 Citations (Scopus)

Endothelial function in healthy young individuals is associated with dietary consumption of saturated fat

Lambert, E. A., Phillips, S., Belski, R., Tursunalieva, A., Eikelis, N., Sari, C. I., Dixon, J. B., Straznicky, N., Grima, M., Head, G. A., Schlaich, M. & Lambert, G. W., 9 Nov 2017, In : Frontiers in Physiology. 8, November, 876.

Research output: Contribution to journalArticle

Open Access
Fats
Hyperemia
Young Adult
Cardiovascular Diseases
Diet
2018

Stressing the Metabolic Powers of Fibroblast Growth Factor 21

Magno, A., Herat, L., Carnagarin, R., Schlaich, M. & Matthews, V., 30 Sep 2018, In : AME Medical Journal.

Research output: Contribution to journalEditorial

Open Access
2019

Blood pressure screening during the May Measurement Month 2017 programme in Vietnam-South-East Asia and Australasia

Van Minh, H., Viet, N. L., Sinh, C. T., Hung, P. N., Mong Ngoc, N. T., Hung, N. V., Son, T. K., Đong, N. T., Thang, Đ. C., Tien, H. A., Tuan, H. C., Beaney, T., Xia, X., Poulter, N. R. & Schlaich, M. P., Apr 2019, In : European Heart Journal Supplements. 21, Suppl D, p. D127-D129

Research output: Contribution to journalArticle

Open Access
Australasia
Far East
Vietnam
Blood Pressure
Hypertension
2017
1 Citation (Scopus)

Hypertension on the ROX: Durable Blood Pressure Lowering With Central Iliac Arteriovenous Anastomosis

Schlaich, M. P., Azzam, O. & Sata, Y., 1 Dec 2017, In : Hypertension (Dallas, Tex. : 1979). 70, 6, p. 1084-1086 3 p.

Research output: Contribution to journalEditorial

2018
2 Citations (Scopus)

Renal denervation: one step backwards, three steps forward

Schlaich, M. P. & Bakris, G. L., Oct 2018, In : Nature Reviews Nephrology. 14, 10, p. 602-604 2 p.

Research output: Contribution to journalEditorial

Denervation
Blood Pressure
Hypertension
Kidney
Therapeutics