Find Research Outputs

Search concepts
Selected filters
2010

Interventionelle renale sympathektomie zur behandlung der therapieresistenten hypertonie

Mahfoud, F., Kindermann, M., Ukena, C., Sobotka, P. A., Kindermann, I., Schlaich, M. & Böhm, M., 8 Oct 2010, In : Journal fur Hypertonie. 14, 3, p. 18-20 3 p.

Research output: Contribution to journalShort survey

Sympathectomy
Denervation
Comorbidity
Hypertension
Kidney
2013
211 Citations (Scopus)

Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 9 Jul 2013, In : Circulation. 128, 2, p. 132-140 9 p.

Research output: Contribution to journalArticle

Open Access
Sympathectomy
Blood Pressure
Hypertension
Kidney
Ambulatory Blood Pressure Monitoring
2011
14 Citations (Scopus)

Recent advances in the treatment of hypertension

Hering, D., Esler, M. D., Krum, H., Mahfoud, F., Böhm, M., Sobotka, P. A. & Schlaich, M. P., 1 Jun 2011, In : Expert Review of Cardiovascular Therapy. 9, 6, p. 729-744 16 p.

Research output: Contribution to journalReview article

Blood Pressure
Hypertension
Life Style
Cause of Death
Therapeutics
2014
14 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Blood pressure
Immune system
Blood Pressure
Plasmas
2012
6 Citations (Scopus)

Effects of renal denervation on insulin resistance

Hering, D., Esler, M. D. & Schlaich, M. P., 1 Nov 2012, In : Expert Review of Cardiovascular Therapy. 10, 11, p. 1381-1386 6 p.

Research output: Contribution to journalReview article

Denervation
Insulin Resistance
Hypertension
Kidney
Comorbidity
2016
13 Citations (Scopus)

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 othersVonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
Denervation
Blood Pressure
Kidney
Pharmaceutical Preparations
Confidence Intervals
2014
3 Citations (Scopus)

Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 2014, In : The Lancet. 383, 9932, p. 1885-1886 2 p.

Research output: Contribution to journalLetter

2012
21 Citations (Scopus)

Laparoscopic adjustable gastric banding and other devices for the management of obesity

Dixon, J. B., Straznicky, N. E., Lambert, E. A., Schlaich, M. P. & Lambert, G. W., 7 Aug 2012, In : Circulation. 126, 6, p. 774-785 12 p.

Research output: Contribution to journalArticle

Open Access
2013
1 Citation (Scopus)
2012
348 Citations (Scopus)

Renal sympathetic denervation for treatment of drug-resistant hypertension: One-year results from the symplicity htn-2 randomized, controlled trial

Esler, M. D., Krum, H., Schlaich, M., Schmieder, R. E., Böhm, M. & Sobotka, P. A., 18 Dec 2012, In : Circulation. 126, 25, p. 2976-2982 7 p.

Research output: Contribution to journalArticle

Open Access
Sympathectomy
Denervation
Randomized Controlled Trials
Blood Pressure
Hypertension
2014
16 Citations (Scopus)

A randomized controlled trial of the effects of pioglitazone treatment on sympathetic nervous system activity and cardiovascular function in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Karapanagiotidis, S., Wong, C., Richards, K., Marusic, P., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. E1701-E1707

Research output: Contribution to journalArticle

Open Access
pioglitazone
Sympathetic Nervous System
Neurology
Norepinephrine
Randomized Controlled Trials
2012
67 Citations (Scopus)

The role of renal denervation in the treatment of heart failure

Sobotka, P. A., Krum, H., Böhm, M., Francis, D. P. & Schlaich, M. P., 1 Jun 2012, In : Current Cardiology Reports. 14, 3, p. 285-292 8 p.

Research output: Contribution to journalReview article

Denervation
Treatment Failure
Heart Failure
Kidney
Vascular Resistance
2010
84 Citations (Scopus)

Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension

Esler, M., Lambert, E. & Schlaich, M., Dec 2010, In : Journal of Applied Physiology. 109, 6, p. 1996-1998 3 p.

Research output: Contribution to journalArticle

2011
684 Citations (Scopus)

Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months

Symplicity HTN-1 Investigators & Schlaich, M., May 2011, In : Hypertension. 57, 5, p. 911-7 7 p.

Research output: Contribution to journalArticle

Sympathectomy
Catheters
Blood Pressure
Hypertension
Kidney

Response to letter regarding article, "effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study"

Mahfoud, F., Schlaich, M., Kindermann, I., Ukena, C., Cremers, B., Brandt, M. C., Hoppe, U. C., Vonend, O., Rump, L. C., Sobotka, P. A., Krum, H., Esler, M. & Böhm, M., 15 Nov 2011, In : Circulation. 124, 20

Research output: Contribution to journalLetter

Open Access
2013
23 Citations (Scopus)

Higher heart rate increases risk of diabetes among men: The Australian Diabetes Obesity and Lifestyle (AusDiab) study

Grantham, N. M., Magliano, D. J., Tanamas, S. K., Söderberg, S., Schlaich, M. P. & Shaw, J. E., Apr 2013, In : Diabetic Medicine. 30, 4, p. 421-427 7 p.

Research output: Contribution to journalArticle

Life Style
Obesity
Heart Rate
Odds Ratio
Urine Specimen Collection
2012
61 Citations (Scopus)

Effects of renal denervation on sympathetic activation, blood pressure, and glucose metabolism in patients with resistant hypertension

Schlaich, M. P., Hering, D., Sobotka, P., Krum, H., Lambert, G. W., Lambert, E. & Esler, M. D., 20 Sep 2012, In : Frontiers in Physiology. 3 FEB, Article 10.

Research output: Contribution to journalReview article

Open Access
Sympathectomy
Blood Glucose
Blood Pressure
Hypertension
Kidney
97 Citations (Scopus)

Ambulatory blood pressure monitoring in Australia: 2011 consensus position statement

Head, G. A., McGrath, B. P., Mihailidou, A. S., Nelson, M. R., Schlaich, M. P., Stowasser, M., Mangoni, A. A., Cowley, D., Brown, M. A., Ruta, L. A. & Wilson, A., Feb 2012, In : Journal of Hypertension. 30, 2, p. 253-266 14 p.

Research output: Contribution to journalArticle

Ambulatory Blood Pressure Monitoring
Ambulatory Monitoring
Blood Pressure
Hypertension
Cardiovascular Diseases
2015
114 Citations (Scopus)

First report of the global SYMPLICITY registry on the effect of renal artery denervation in patients with uncontrolled hypertension

Böhm, M., Mahfoud, F., Ukena, C., Hoppe, U. C., Narkiewicz, K., Negoita, M., Ruilope, L., Schlaich, M., Schmieder, R. E., Whitbourn, R., Williams, B., Zeymer, U., Zirlik, A. & Mancia, G., 2015, In : Hypertension. 65, 4, p. 766-774

Research output: Contribution to journalArticle

Denervation
Renal Artery
Registries
Blood Pressure
Hypertension
2017
16 Citations (Scopus)

A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism

Marques, F. Z., Eikelis, N., Bayles, R. G., Lambert, E. A., Straznicky, N. E., Hering, D., Esler, M. D., Head, G. A., Barton, D. A., Schlaich, M. P. & Lambert, G. W., 1 Jan 2017, In : Molecular Psychiatry. 22, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

Norepinephrine Plasma Membrane Transport Proteins
MicroRNAs
Cardiovascular Diseases
Postural Orthostatic Tachycardia Syndrome
Genes
2014
153 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
Denervation
Catheters
Randomized Controlled Trials
Blood Pressure
Hypertension
1 Citation (Scopus)

Substantial blood pressure reduction with renal denervation in a drug-naïve patient intolerant to antihypertensive pharmacotherapy: A case report

Xu, J., Walton, A., Hering, D., Sata, Y. & Schlaich, M. P., 2014, In : Journal of Human Hypertension. 28, 8, p. 517-518 2 p.

Research output: Contribution to journalLetter

2017
13 Citations (Scopus)

Effect of renal denervation on kidney function in patients with chronic kidney disease

Hering, D., Marusic, P., Duval, J., Sata, Y., Head, G. A., Denton, K. M., Burrows, S., Walton, A. S., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : International Journal of Cardiology. 232, p. 93-97 5 p.

Research output: Contribution to journalArticle

Denervation
Chronic Renal Insufficiency
Kidney
Glomerular Filtration Rate
Blood Pressure
2010
205 Citations (Scopus)

Sympathetic nervous activation in obesity and the metabolic syndrome-Causes, consequences and therapeutic implications

Lambert, G. W., Straznicky, N. E., Lambert, E. A., Dixon, J. B. & Schlaich, M. P., 1 May 2010, In : Pharmacology and Therapeutics. 126, 2, p. 159-172 14 p.

Research output: Contribution to journalReview article

Obesity
Kidney
Adipokines
Sympathetic Nervous System
Hyperinsulinism
2011
143 Citations (Scopus)

Sympatho-renal axis in chronic disease

Sobotka, P. A., Mahfoud, F., Schlaich, M. P., Hoppe, U. C., Böhm, M. & Krum, H., Dec 2011, In : Clinical Research in Cardiology. 100, 12, p. 1049-1057 9 p.

Research output: Contribution to journalReview article

Open Access
Chronic Disease
Kidney
Insulin Resistance
Diuretics
Heart Failure
2010
133 Citations (Scopus)

Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults

Lambert, E., Sari, C. I., Dawood, T., Nguyen, J., McGrane, M., Eikelis, N., Chopra, R., Wong, C., Chatzivlastou, K., Head, G., Straznicky, N., Esler, M., Schlaich, M. & Lambert, G., 1 Sep 2010, In : Hypertension. 56, 3, p. 351-358 8 p.

Research output: Contribution to journalArticle

Open Access
Sympathetic Nervous System
Young Adult
Obesity
Muscles
Kidney
2016
2014
21 Citations (Scopus)

Sympathetic activity and markers of cardiovascular risk in nondiabetic severely obese patients: The effect of the initial 10% weight loss

Lambert, E. A., Rice, T., Eikelis, N., Straznicky, N. E., Lambert, G. W., Head, G. A., Hensman, C., Schlaich, M. P. & Dixon, J. B., 2014, In : American Journal of Hypertension. 27, 10, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Open Access
Weight Loss
Blood Pressure
Sympathetic Nervous System
Stomach
Baroreflex
2013
38 Citations (Scopus)

Rationale and design of a large registry on renal denervation: The Global SYMPLICITY registry

Böhm, M., Mahfoud, F., Ukena, C., Bauer, A., Fleck, E., Hoppe, U. C., Kintscher, U., Narkiewicz, K., Negoita, M., Ruilope, L., Rump, L. C., Schlaich, M., Schmieder, R., Sievert, H., Weil, J., Williams, B., Zeymer, U. & Mancia, G., Aug 2013, In : EuroIntervention. 9, 4, p. 484-492 9 p.

Research output: Contribution to journalArticle

Denervation
Registries
Hypertension
Kidney
Renal Artery
2012
79 Citations (Scopus)

Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: Obesity and difficult to treat arterial hypertension

Jordan, J., Yumuk, V., Schlaich, M., Nilsson, P. M., Zahorska-Markiewicz, B., Grassi, G., Schmieder, R. E., Engeli, S. & Finer, N., 1 Jun 2012, In : Journal of Hypertension. 30, 6, p. 1047-1055 9 p.

Research output: Contribution to journalArticle

Obesity
Antihypertensive Agents
Hypertension
Weight Loss
Guidelines
14 Citations (Scopus)

Autonomic responses to stress in Black versus Caucasian Africans: The SABPA Study

Reimann, M., Hamer, M., Schlaich, M., Malan, N. T., Rüdiger, H., Ziemssen, T. & Malan, L., 2012, In : Psychophysiology. 49, 4, p. 454-461 8 p.

Research output: Contribution to journalArticle

Baroreflex
Down-Regulation
Color
Heart Rate
2013
10 Citations (Scopus)

Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: The sympathetic activity and ambulatory blood pressure in Africans study

Reimann, M., Hamer, M., Malan, N. T., Schlaich, M. P., Lambert, G. W., Ziemssen, T., Boeger, R. H. & Malan, L., 2013, In : Psychosomatic Medicine. 75, 8, p. 751-758 8 p.

Research output: Contribution to journalArticle

Arginine
Nitric Oxide
Blood Pressure
Psychology
Cardiovascular Diseases
2011
58 Citations (Scopus)

Exercise augments weight loss induced improvement in renal function in obese metabolic syndrome individuals

Straznicky, N. E., Grima, M. T., Lambert, E. A., Eikelis, N., Dawood, T., Lambert, G. W., Nestel, P. J., Masuo, K., Sari, C. I., Chopra, R., Mariani, J. A. & Schlaich, M. P., 1 Mar 2011, In : Journal of Hypertension. 29, 3, p. 553-564 12 p.

Research output: Contribution to journalArticle

Weight Loss
Albuminuria
Baroreflex
Exercise
Glomerular Filtration Rate
2014
1 Citation (Scopus)

Hypertension: Treatment-resistant hypertension-A risk factor for ESRD

Schlaich, M. P., 2014, In : Nature Reviews Nephrology. 10, 4, p. 189-190 2 p.

Research output: Contribution to journalEditorial

2015
42 Citations (Scopus)

Metabolic syndrome: A sympathetic disease?

Schlaich, M., Straznicky, N., Lambert, E. & Lambert, G., 1 Feb 2015, In : The Lancet Diabetes and Endocrinology. 3, 2, p. 148-157 10 p.

Research output: Contribution to journalComment/debate

Sympathetic Nervous System
Blood Glucose
Weight Loss
Pharmacology
Exercise
2016
2 Citations (Scopus)
168 Downloads (Pure)

Central Sympathetic Inhibition: a Neglected Approach for Treatment of Cardiac Arrhythmias?

Cagnoni, F., Destro, M., Bontempelli, E., Locatelli, G., Hering, D. & Schlaich, M., Feb 2016, In : Current Hypertension Reports. 18, 2, p. 1-11 11 p., 13.

Research output: Contribution to journalReview article

Open Access
File
Atrial Fibrillation
Cardiac Arrhythmias
moxonidine
Sympathetic Nervous System
Therapeutics
6 Citations (Scopus)
Sympathectomy
Chronic Kidney Failure
Catheters
Kidney
Denervation
2017
2 Citations (Scopus)

The metalloproteinase ADAM28 promotes metabolic dysfunction in mice

Herat, L., Rudnicka, C., Okada, Y., Mochizuki, S., Schlaich, M. & Matthews, V., 21 Apr 2017, In : International Journal of Molecular Sciences. 18, 4, 12 p., 884.

Research output: Contribution to journalArticle

Open Access
obesity
Disintegrins
Metalloproteases
mice
aspartates
2015
9 Citations (Scopus)

Device-based approaches for renal nerve ablation for hypertension and beyond

Thorp, A. A. & Schlaich, M., 8 Jul 2015, In : Frontiers in Physiology. 6, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
Hypertension
Kidney
Equipment and Supplies
Denervation
Blood Pressure
2014
16 Citations (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

Denervation
Sympathetic Nervous System
Kidney
Hypertension
Sympatholytics
2013
19 Citations (Scopus)
Open Access
moxonidine
Imidazolines
Blood Pressure
Hypertension
Population
2014
41 Citations (Scopus)

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

Reperfusion Injury
Kidney
Reperfusion
Ischemia
Cell Hypoxia
2010
34 Citations (Scopus)

Renal sympathetic nerve ablation: The new frontier in the treatment of hypertension

Schlaich, M. P., Krum, H. & Sobotka, P. A., 1 Feb 2010, In : Current Hypertension Reports. 12, 1, p. 39-46 8 p.

Research output: Contribution to journalReview article

Blood Pressure
Hypertension
Kidney
Neural Pathways
Renal Circulation
2016
45 Citations (Scopus)

Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: A double-blind, randomized, crossover trial

De Courten, B., De Courten, M. P. J., Soldatos, G., Dougherty, S. L., Straznicky, N., Schlaich, M., Sourris, K. C., Chand, V., Scheijen, J. L. J. M., Kingwell, B. A., Cooper, M. E., Schalkwijk, C. G., Walker, K. Z. & Forbes, J. M., 1 Jun 2016, In : American Journal of Clinical Nutrition. 103, 6, p. 1426-1433 8 p.

Research output: Contribution to journalArticle

Open Access
Advanced Glycosylation End Products
Cross-Over Studies
Insulin Resistance
Diet
Type 2 Diabetes Mellitus
2010
10 Citations (Scopus)

New therapeutic approaches to resistant hypertension

Schlaich, M. P., Krum, H. & Esler, M. D., Aug 2010, In : Current Hypertension Reports. 12, 4, p. 296-302 7 p.

Research output: Contribution to journalReview article

Hypertension
Blood Pressure
Antihypertensive Agents
Therapeutics
Equipment and Supplies
2015
27 Citations (Scopus)

Role of the Sympathetic Nervous System in Stress-Mediated Cardiovascular Disease

Hering, D., Lachowska, K. & Schlaich, M., Oct 2015, In : Current Hypertension Reports. 17, 10, p. 1-9 9 p., 80.

Research output: Contribution to journalReview article

Sympathetic Nervous System
Cardiovascular Diseases
Hypertension
Fatal Outcome
Sudden Cardiac Death
2010
3 Citations (Scopus)

Rebuttal from Esler, Lambert, and Schlaich.

Esler, M., Lambert, E. & Schlaich, M., 2010, In : Journal of applied physiology (Bethesda, Md. : 1985). 109, 6, p. 2000-2001 2 p.

Research output: Contribution to journalComment/debate

2013
18 Citations (Scopus)

Percutaneous transluminal renal denervation: A potential treatment option for polycystic kidney disease-related pain?

Shetty, S., Roberts, T. J. & Schlaich, M. P., 2013, In : International Journal of Cardiology. 162, 3, p. e58-e59

Research output: Contribution to journalLetter

2011
27 Citations (Scopus)

Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P., Hilgers, K. F. & Schmieder, R. E., Jun 2011, In : Pharmacogenetics and Genomics. 21, 6, p. 347-349 3 p.

Research output: Contribution to journalArticle

Renin
Blood Pressure
Genes
Alleles
Renin-Angiotensin System
2016
5 Citations (Scopus)

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer

Hoyne, G., Rudnicka, C., Sang, Q. X., Roycik, M., Howarth, S., Leedman, P., Schlaich, M., Candy, P. & Matthews, V., 2016, In : BMC Cancer. 16, 12 p., 151.

Research output: Contribution to journalArticle

Open Access
Disintegrins
Metalloproteases
Prostatic Neoplasms
Biomarkers
Prostate