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2017
15 Citations (Scopus)

Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca2+–NFATc1 signaling pathway and prevents ovariectomy-induced bone loss

Zeng, X., Zhang, Y., Wang, S., Wang, K., Tao, L., Zou, M., Chen, N., Xu, J., Liu, S. & Li, X., 15 Jan 2017, In : Biochemical Pharmacology. 124, p. 57-68 12 p.

Research output: Contribution to journalArticle

Ovariectomy
Osteogenesis
Bone
Bone and Bones
Calcineurin
2016
53 Citations (Scopus)

Star-Shaped Amphiphilic Hyperbranched Polyglycerol Conjugated with Dendritic Poly(L-lysine) for the Codelivery of Docetaxel and MMP-9 siRNA in Cancer Therapy

Zhou, X., Zheng, Q., Wang, C., Xu, J., Wu, J. P., Kirk, T. B., Ma, D. & Xue, W., 2016, In : ACS Applied Materials and Interfaces. 8, 20, p. 12609-12619 11 p.

Research output: Contribution to journalArticle

docetaxel
Matrix Metalloproteinases
Small Interfering RNA
Lysine
Stars
2015
7 Citations (Scopus)

Caffeic Acid Phenethyl Ester Abrogates Bone Resorption in a Murine Calvarial Model of Polyethylene Particle-Induced Osteolysis

Zawawi, M. S. F., Perilli, E., Stansborough, R. L., Marino, V., Cantley, M. D., Xu, J., Dharmapatni, A. A. S. S. K., Haynes, D. R., Gibson, R. J. & Crotti, T. N., 2015, In : Calcified Tissue International. 96, 6, p. 565-574

Research output: Contribution to journalArticle

Osteolysis
Polyethylene
Bone Resorption
Osteoclasts
Gastrointestinal Tract
2012
28 Citations (Scopus)

miR-764-5p promotes osteoblast differentiation through inhibition of CHIP/STUB1 expression

Guo, J., Ren, F., Wang, Y., Li, S., Gao, Z., Wang, X., Ning, H., Wu, J., Li, Y., Wang, Z., Chim, S., Xu, J. & Chang, Z., 2012, In : Journal of Bone and Mineral Research. 27, p. 1607-1618

Research output: Contribution to journalArticle

2014
39 Citations (Scopus)

The role of SATB2 in skeletogenesis and human disease

Zhao, X., Qu, Z., Tickner, J., Xu, J., Dai, K. & Zhang, X., 2014, In : Cytokine and Growth Factor Reviews. 25, p. 35–44

Research output: Contribution to journalLiterature review

2017
13 Citations (Scopus)

Mechanical Stress Regulates Bone Metabolism Through MicroRNAs

Yuan, Y., Zhang, L., Tong, X., Zhang, M., Zhao, Y., Guo, J., Lei, L., Chen, X., Tickner, J., Xu, J. & Zou, J., 1 Jun 2017, In : Journal of Cellular Physiology. 232, 6, p. 1239-1245 7 p.

Research output: Contribution to journalArticle

Mechanical Stress
MicroRNAs
Metabolism
Bone
Bone and Bones
2015
12 Citations (Scopus)

Non-severe burn injury leads to depletion of bone volume that can be ameliorated by inhibiting TNF-α

O'Halloran, E., Kular, J., Xu, J., Wood, F. & Fear, M., May 2015, In : Burns. 41, 3, p. 558-564

Research output: Contribution to journalArticle

Bone and Bones
Wounds and Injuries
Anti-Idiotypic Antibodies
Body Surface Area
Burns
2016
7 Citations (Scopus)

Hemocompatibility evaluation in vitro of methoxy polyethyleneglycol-polycaprolactone copolymer solutions

Hu, Q., Zhang, Y., Wang, C., Xu, J., Wu, J., Liu, Z. & Xue, W., 2016, In : Journal of Biomedical Materials Research - Part A. 104, 3, p. 802-812

Research output: Contribution to journalArticle

Polycaprolactone
Copolymers
Blood
Platelets
Fibrinogen
2011
52 Citations (Scopus)

In situ accumulation of advanced glycation endproducts (AGEs) in bone matrix and its correlation with osteoclastic bone resorption

Dong, X. N., Qin, A., Xu, J. & Wang, X., 2011, In : Bone. 49, p. 174-183

Research output: Contribution to journalArticle

2014
10 Citations (Scopus)

International Combined Orthopaedic Research Societies: A model for international collaboration to promote orthopaedic and musculoskeletal research

Miclau, T., Adachi, N., Antoniou, J., Baldini, N., Blunn, G., Boyd, S., Chang, JK., Grimm, B., Guo, X. E., Im, GI., Kim, SY., Korkusuz, F., Lee, OKS., Mccaskie, A., Richards, R. G., Shetty, G., Sivananthan, S., Tang, T., Xu, J. & Qin, L., 2014, In : Journal of Orthopaedic Translation. Online, p. 1-6

Research output: Contribution to journalLetter

Open Access
2015
10 Citations (Scopus)

Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation

Fan, X., Xiong, H., Wei, J., Gao, X., Feng, Y., Liu, X., Zhang, G., He, Q. Y., Xu, J. & Liu, L., 2015, In : Scientific Reports. 5, p. Article 17732

Research output: Contribution to journalArticle

Open Access
Heterogeneous-Nuclear Ribonucleoprotein K
Glycogen Synthase Kinase 3
Osteoclasts
Phosphorylation
Physiological Phenomena
8 Citations (Scopus)

Comparative and quantitative proteomic analysis of normal and degenerated human annulus fibrosus cells

Ye, D., Liang, W., Dai, L., Zhou, L., Yao, Y., Zhong, X., Chen, H. & Xu, J., 2015, In : Clinical and Experimental Pharmacology and Physiology. 42, 5, p. 530-536

Research output: Contribution to journalArticle

Proteomics
Intervertebral Disc Degeneration
Proteins
Adenosine A3 Receptors
Guanine Nucleotides
2017
7 Citations (Scopus)

Massage alleviates delayed onset muscle soreness after strenuous exercise: A systematic review and meta-analysis

Guo, J., Li, L., Gong, Y., Zhu, R., Xu, J., Zou, J. & Chen, X., 27 Sep 2017, In : Frontiers in Physiology. 8, 747.

Research output: Contribution to journalReview article

Open Access
Massage
Myalgia
Meta-Analysis
Torque
Creatine Kinase
16 Citations (Scopus)

Biocompatible hyperbranched polyglycerol modified β-cyclodextrin derivatives for docetaxel delivery

Xu, Z., Zhang, Y., Hu, Q., Tang, Q., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Feb 2017, In : Materials Science and Engineering C. 71, p. 965-972 8 p.

Research output: Contribution to journalArticle

docetaxel
Chemotherapy
Cyclodextrins
Drug delivery
Biocompatibility
2016
10 Citations (Scopus)

Sinomenine down-regulates TLR4/TRAF6 expression and attenuates lipopolysaccharide-induced osteoclastogenesis and osteolysis

He, L., Duan, H., Li, X., Wang, S., Zhang, Y., Lei, L., Xu, J. & Liu, S., 2016, In : European Journal of Pharmacology. 779, p. 66-79

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Osteolysis
Osteogenesis
Osteoclasts
Lipopolysaccharides
2015
15 Citations (Scopus)

Macrophage migration inhibitory factor is essential for osteoclastogenic mechanisms in vitro and in vivo mouse model of arthritis

Gu, R., Santos, L. L., Ngo, D., Fan, H., Singh, P. P., Fingerle-Rowson, G. R., Bucala, R. J., Xu, J., Quinn, J. M. W. & Morand, E. F., Apr 2015, In : Cytokine. 72, 2, p. 135-145

Research output: Contribution to journalArticle

Macrophage Migration-Inhibitory Factors
Osteoclasts
Arthritis
Osteogenesis
Rheumatoid Arthritis
2014
2 Citations (Scopus)

Construction and biomechanical properties of polyaxial self-locking anatomical plate based on the geometry of distal tibia

Liang, W., Ye, W., Ye, D., Zhou, Z., Chen, Z., Li, A., Xie, Z., Zhang, L. & Xu, J., 2014, In : BioMed Research International. 2014, p. 1-7

Research output: Contribution to journalArticle

Open Access
Tibia
Geometry
Fracture fixation
Torsional stress
Display devices
2016
13 Citations (Scopus)

Deficiency of sorting nexin 10 prevents bone erosion in collagen-induced mouse arthritis through promoting NFATc1 degradation

Zhou, C., You, Y., Shen, W., Zhu, Y. Z., Peng, J., Feng, H. T., Wang, Y., Li, D., Shao, W. W., Li, C. X., Li, W. Z., Xu, J. & Shen, X., 2016, In : Annals of the Rheumatic Diseases. n/a, p. 1-8

Research output: Contribution to journalArticle

2013
27 Citations (Scopus)
293 Downloads (Pure)

Divergent effects of endogenous and exogenous glucocorticoid-induced leucine zipper in animal models of inflammation and arthritis

Ngo, D., Beaulieu, E., Gu, R., Leaney, A., Santos, L., Fan, H., Yang, Y., Kao, W., Xu, J., Escriou, V., Loiler, S. A., Vervoordeldonk, M. J. B. M. & Morand, E. F., 2013, In : ARTHRITIS AND RHEUMATISM. 65, 5, p. 1203-1212

Research output: Contribution to journalArticle

Open Access
File
Leucine Zippers
Glucocorticoids
Arthritis
Animal Models
Inflammation
2010
27 Citations (Scopus)

Cellular response and extracellular matrix breakdown in rotator cuff tendon rupture

Wu, B., Chen, J., Dela Rosa, T., Yu, Q., Wang, A., Xu, J. & Zheng, M., 2010, In : Archives of Orthopaedic and Trauma Surgery. 131, p. 405-411

Research output: Contribution to journalArticle

2015
6 Citations (Scopus)
124 Downloads (Pure)

Natural Germacrane Sesquiterpenes Inhibit Osteoclast Formation, Bone Resorption, RANKL-Induced NF-B Activation, and IB Degradation

Qin, S., Ang, E., Dai, L., Yang, X., Ye, D., Chen, H., Zhou, L., Yang, M., Teguh, D. A., Tan, R., Xu, J., Tickner, J., Pavlos, N. & Xu, J., 5 Nov 2015, In : International Journal of Molecular Sciences. 16, 11, p. 26599–26607 9 p.

Research output: Contribution to journalArticle

Open Access
File
Germacrane Sesquiterpenes
osteogenesis
Osteoclasts
Bone Resorption
bones
13 Citations (Scopus)

Parthenolide inhibits pro-inflammatory cytokine production and exhibits protective effects on progression of collagen-induced arthritis in a rat model

Liu, Q., Zhao, J., Tan, R., Zhou, H., Lin, Z., Zheng, M., Romas, E., Xu, J. & Sims, NA., May 2015, In : Scandinavian Journal of Rheumatology. 44, 3, p. 182-191

Research output: Contribution to journalArticle

Experimental Arthritis
Cytokines
NF-kappa B
Arthritis
Cartilage
2012

Introduction: Understanding the signalling mechanisms in molecular physiology and diseases

Liu, J-P. & Xu, J., 1 Aug 2012, In : Clinical and Experimental Pharmacology and Physiology. 39, 8, p. 658-660

Research output: Contribution to journalReview article

2014
20 Citations (Scopus)

Electrochemical behavior of (Ti1-xNbx) 5Si3 nanocrystalline films in simulated physiological media

Liu, L., Xu, J., Munroe, P. R., Xu, J. & Xie, Z., 2014, In : Acta Biomaterialia. 10, 2, p. 1005-1013

Research output: Contribution to journalArticle

Caustics
Corrosion
Electrochemical Techniques
Dielectric Spectroscopy
Cochlear Implants
2017
8 Citations (Scopus)

The Emerging Role of MORC Family Proteins in Cancer Development and Bone Homeostasis

Hong, G., Qiu, H., Wang, C., Jadhav, G., Wang, H., Tickner, J., He, W. & Xu, J., 1 May 2017, In : Journal of Cellular Physiology. 232, 5, p. 928-934 7 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Bone
Homeostasis
Zinc Fingers
Proteins
2016
112 Citations (Scopus)

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

Li, D., Liu, J., Guo, B., Liang, C., Dang, L., Lu, C., He, X., Cheung, H. Y. S., Xu, L., He, B., Liu, B., Shaikh, A. B., Li, F., Wang, L., Yang, Z., Au, D. W. T., Peng, S., Zhang, Z., Zhang, B. T., Pan, X. & 13 othersQian, A., Shang, P., Xiao, L., Jiang, B., Wong, C. K. C., Xu, J., Bian, Z., Liang, Z., Guo, D. A., Zhu, H., Tan, W., Lu, A. & Zhang, G., 2016, In : Nature Communications. 7

Research output: Contribution to journalArticle

osteogenesis
Osteoclasts
Osteogenesis
Bone
osteoblasts
2018
3 Citations (Scopus)

TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

Zuo, C., Zhao, X., Shi, Y., Wu, W., Zhang, N., Xu, J., Wang, C., Hu, G. & Zhang, X., 1 Jan 2018, In : Oncotarget. 9, 4, p. 4833-4850 18 p.

Research output: Contribution to journalArticle

Open Access
AT Rich Sequence
Osteoblasts
Carrier Proteins
Tumor Necrosis Factor-alpha
Mitogen-Activated Protein Kinase 3
3 Citations (Scopus)

Inhibitory effects of tubeimoside I on synoviocytes and collagen-induced arthritis in rats

Liu, Z., Zhou, L., Ma, X., Sun, S., Qiu, H., Li, H., Xu, J. & Liu, M., 1 Nov 2018, In : Journal of Cellular Physiology. 233, 11, p. 8740-8753 14 p.

Research output: Contribution to journalArticle

Experimental Arthritis
Rats
Collagen
Rheumatoid Arthritis
Down-Regulation
2017
2 Citations (Scopus)

Evaluation of N-phosphonium chitosan as a novel vaccine carrier for intramuscular immunization

Cai, J., Zhang, W., Xu, J., Xue, W. & Liu, Z., 1 Nov 2017, In : Journal of Biomaterials Applications. 32, 5, p. 677-685 9 p.

Research output: Contribution to journalArticle

Immunization
Vaccines
Chitosan
Antigens
Water
2019
4 Citations (Scopus)

Daphnetin attenuates LPS-induced osteolysis and RANKL mediated osteoclastogenesis through suppression of ERK and NFATc1 pathways

Wu, Z., Wu, H., Li, C., Fu, F., Ding, J., Shao, S., Li, K., Yu, X., Su, Y., Liang, J., Lin, X., Yuan, G., Zhou, J., Song, F., Zhao, J., Xu, J., Liu, Q. & Xu, F., 1 Oct 2019, In : Journal of Cellular Physiology. 234, 10, p. 17812-17823 12 p.

Research output: Contribution to journalArticle

Osteolysis
MAP Kinase Signaling System
Osteogenesis
Bone
Prosthetics
2018
18 Citations (Scopus)

Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways

Cheng, J., Zhou, L., Liu, Q., Tickner, J., Tan, Z., Li, X., Liu, M., Lin, X., Wang, T., Pavlos, N. J., Zhao, J. & Xu, J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2502-2512 11 p.

Research output: Contribution to journalArticle

Ovariectomy
Osteogenesis
Osteoporosis
Osteoclasts
Bone
2017

Melphalan modifies the bone microenvironment by enhancing osteoclast formation

Chai, R. C., McDonald, M. M., Terry, R. L., Kovacic, N., Down, J. M., Pettitt, J. A., Mohanty, S. T., Shah, S., Haffari, G., Xu, J., Gillespie, M. T., Rogers, M. J., Price, J. T., Croucher, P. I. & Quinn, J. M. W., 15 Sep 2017, In : Oncotarget. 8, 40, p. 68047-68058 12 p.

Research output: Contribution to journalArticle

Open Access
2013
6 Citations (Scopus)
Open Access
2018
2 Citations (Scopus)

Redox-responsive chemosensitive polyspermine delivers ursolic acid targeting to human breast tumor cells: The depletion of intracellular GSH contents arouses chemosensitizing effects

Ji, X., Tang, Q., Pang, P., Wu, J., Kirk, T. B., Xu, J., Ma, D. & Xue, W., 1 Oct 2018, In : Colloids and Surfaces B: Biointerfaces. 170, p. 293-302 10 p.

Research output: Contribution to journalArticle

breast
Oxidation-Reduction
Tumors
depletion
tumors
2017
55 Downloads (Pure)
File
Libraries
Phenotype
Bone and Bones
Genes
Chromosome Mapping
2018
11 Citations (Scopus)

Roles of neurotrophins in skeletal tissue formation and healing

Su, Y. W., Zhou, X. F., Foster, B. K., Grills, B. L., Xu, J. & Xian, C. J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2133-2145 13 p.

Research output: Contribution to journalReview article

Nerve Growth Factors
Tissue
Bone
Nerve Growth Factor Receptors
Angiogenesis Inducing Agents
7 Citations (Scopus)

Synthesis of Janus Au nanorods/polydivinylbenzene hybrid nanoparticles for chemo-photothermal therapy

Wang, Y., Ji, X., Pang, P., Shi, Y., Dai, J., Xu, J., Wu, J., Kirk, T. B. & Xue, W., 28 Apr 2018, In : Journal of Materials Chemistry B. 6, 16, p. 2481-2488 8 p.

Research output: Contribution to journalArticle

2015
4 Citations (Scopus)

Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments

Yang, X., Teguh, D., Wu, J. P., He, B., Kirk, T. B., Qin, S., Li, S., Chen, H., Xue, W., Ng, B., Chim, S., Tickner, J. & Xu, J., 17 Aug 2015, In : Arthritis Research and Therapy. 17, 1, p. 1-8

Research output: Contribution to journalArticle

Open Access
Articular Cartilage
Chondrocytes
Knockout Mice
Joints
Bone and Bones
2019
5 Citations (Scopus)

Double network shape memory hydrogels activated by near-infrared with high mechanical toughness, nontoxicity, and 3D printability

Dai, W., Guo, H., Gao, B., Ruan, M., Xu, L., Wu, J., Kirk, T. B., Xu, J., Ma, D. & Xue, W., 15 Jan 2019, In : Chemical Engineering Journal. 356, p. 934-949 16 p.

Research output: Contribution to journalArticle

2018
15 Citations (Scopus)
Cyclodextrins
Grafts
Genes
Doxorubicin
Derivatives
13 Citations (Scopus)

Green synthesis of lignin nanoparticle in aqueous hydrotropic solution toward broadening the window for its processing and application

Chen, L., Zhou, X., Shi, Y., Gao, B., Wu, J., Kirk, T. B., Xu, J. & Xue, W., 15 Aug 2018, In : Chemical Engineering Journal. 346, p. 217-225 9 p.

Research output: Contribution to journalArticle

Lignin
lignin
aqueous solution
Nanoparticles
drug
2017

Natural Compounds for the Treatment of Psoriatic Arthritis: A Proposal Based on Multi-Targeted Osteoclastic Regulation and on a Preclinical Study

Deng, S., Cheng, J., Zhao, J., Yao, F. & Xu, J., 11 Jul 2017, In : JMIR Research Protocols. 6, 7, e132.

Research output: Contribution to journalArticle

Open Access
Psoriatic Arthritis
Biological Products
Computer Simulation
Bone Resorption
Arthritis
2018
8 Citations (Scopus)

The emerging role of Hippo signaling pathway in regulating osteoclast formation

Yang, W., Han, W., Qin, A., Wang, Z., Xu, J. & Qian, Y., 1 Jun 2018, In : Journal of Cellular Physiology. 233, 6, p. 4606-4617 12 p.

Research output: Contribution to journalReview article

Osteoclasts
Bone
Molecules
Homeostasis
Osteogenesis
2014

TAK1 inhibition for the prevention of inflammation-induced preterm birth

Ireland, D., Pugazhenthi, K., Xu, J. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

Research output: Chapter in Book/Conference paperConference paper

2019

Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

Liu, Y., Wang, C., Wang, G., Sun, Y., Deng, Z., Chen, L., Chen, K., Tickner, J., Kenny, J., Song, D., Zhang, Q., Wang, H., Chen, Z., Zhou, C., He, W. & Xu, J., 2019, In : Theranostics. 9, 16, p. 4648-4662 15 p.

Research output: Contribution to journalArticle

Open Access
Osteogenesis
Osteoclasts
Osteoporosis
Reactive Oxygen Species
Bone Resorption
2011
52 Citations (Scopus)

EGFL6 promotes endothelial cell migration and angiogenesis through the activation of Extracellular Signal-regulated Kinase

Chim, S., Qin, A., Tickner, J., Pavlos, N., Davey, T. N., Wang, H., Guo, Y., Zheng, M. & Xu, J., 2011, In : Journal of Biological Chemistry. 286, 25, p. 22035-22046

Research output: Contribution to journalArticle

59 Citations (Scopus)

Mangiferin Attenuates Osteoclastogenesis, Bone Resorption, and RANKL-Induced Activation of NF-kB and ERK

Ang, E., Liu, Q., Qi, M., Liu, H. G., Yang, X., Chen, H., Zheng, M. & Xu, J., 2011, In : Journal of Cellular Biochemistry. 112, 1, p. 89-97

Research output: Contribution to journalArticle

2018
17 Citations (Scopus)
313 Downloads (Pure)

Coupling factors and exosomal packaging microRNAs involved in the regulation of bone remodelling

Zhu, S., Yao, F., Qiu, H., Zhang, G., Xu, H. & Xu, J., Feb 2018, In : Biological Reviews. 93, 1, p. 469-480 12 p.

Research output: Contribution to journalArticle

Open Access
File
2013
26 Citations (Scopus)

SC-514, a selective inhibitor of IKKβ attenuates RANKL-induced osteoclastogenesis and NF-κB activation

Liu, Q., Wu, H., Chim, S., Zhou, L., Zhao, J., Feng, H., Wei, Q., Wang, Q., Zheng, M., Tan, R. X., Gu, Q., Xu, J., Pavlos, N., Tickner, J. & Xu, J., 2013, In : Biochemical Pharmacology. 86, 12, p. 1775-1783

Research output: Contribution to journalArticle

2019
8 Citations (Scopus)

MiR-214 is an important regulator of the musculoskeletal metabolism and disease

Sun, Y., Kuek, V., Liu, Y., Tickner, J., Yuan, Y., Chen, L., Zeng, Z., Shao, M., He, W. & Xu, J., Jan 2019, In : Journal of Cellular Physiology. 234, 1, p. 231-245 15 p.

Research output: Contribution to journalReview article