96-74: BioMonitor 2 Pilot Study: Subcutaneous Electrocardiograms Transmitted by Home Monitoring

Ben Ng, Suresh Singarayar, Kevin Hellestrand, Peter Illies, Uwais Mohamed, Shakeeb Razak, Rukshen Weerasooriya, Sze-Yuan Ooi

Research output: Contribution to journalAbstract/Meeting Abstractpeer-review

Abstract

Purpose of the study: The BioMonitor 2 Pilot Study was a first-in-human study investigating the second generation insertable cardiac monitor, the BioMonitor 2 (Biotronik, Berlin, Germany). Here, we report the detection of arrhythmias, and the remote monitoring transmission. Method used: This was a prospective, multi-center, single-arm study in 5 sites across Australia. The BioMonitor 2 automatically detects atrial fibrillation, bradycardia, sudden rate drops, asystole and high ventricular rate episodes. It can store up to 54 subcutaneous ECG (sECG) episodes, with capacity to transmit up to 6 per day. Here, we analyse the episodes which were transmitted by the Home Monitoring system. The observation period totalled 588 patient-days, with 21 patients observed for 28 days after they received optimised device software. Summary of results: Most patients received the device for the investigation of atrial arrhythmias (48%) or syncope (38%). 16 patients (76%) transmitted at least one sECG. The median number of sECGs per patient was 7 (Interquartile range [IQR] 3-37). From 2 patients, more episodes were transmitted within 28 days than the device could store (78 and 128, respectively). During the observation period, 391 sECGs were transmitted on 129 patient-days (22% of the observation period), with a median of 2 sECGs per day (IQR 1-5). On 40 of these days (31%), episodes of more than one arrhythmia type were transmitted. Conclusion: We conclude that the daily transmission of multiple episodes may be helpful in the management of patients with an indication for an insertable cardiac monitor. More than one episode was detected on over half of the days with arrhythmias, and frequently, different arrhythmia types were detected within one day. The ability to automatically transmit up to 6 sECGs per day may make clinically relevant information available in time, and additionally prevent episodes from being lost due to memory limitations.
Original languageEnglish
Pages (from-to)i80-i80
JournalEuropace
Volume18
Issue numbersuppl_1
DOIs
Publication statusPublished - Jun 2016

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