2005 Gregg Lecture: Congenital cataract - From rubella to genetics

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Abstract

On the 65th anniversary of Gregg's observation 'Congenital cataract following German measles in the mother', rubella has retired as the leading cause of congenital cataract, from 87% of Gregg's cohort to less than 3% over the last 25 years and almost zero now in Australia and other developed countries. However, people must keep vigilance in maintaining immunization rates and encourage immunization in developing countries. At least one-fifth of congenital cataract is familial. Understanding the genetics of familial cataract will lead to better treatment of congenital as well as age-related cataract.
Original languageEnglish
Pages (from-to)199-207
JournalClinical and Experimental Ophthalmology
Volume34
Issue number3
DOIs
Publication statusPublished - 2006

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