TY - JOUR
T1 - 11-Hydroxy-3,3-dimethyl-7,12-dioxo-3,4,6,6a,7,12,12a,12b-octahydrobenz[a]anthracen-1-yl acetate
AU - Rozek, T.
AU - Bowie, J.H.
AU - Skelton, Brian
AU - White, Allan
PY - 2003
Y1 - 2003
N2 - The Diels-Alder reaction between 5-hydroxy-1,4-naphthoquinone and 5,5-dimethyl-3-vinyl-1,2-cyclohexadienyl acetate by endo addition gives the title compound, C22H22O5, in 68% yield. This racemic diastereoisomer has the opposite regiochemistry to ochromycinone analogues produced previously and may allow access to a new type of anticancer-active saquayamycin analogue.
AB - The Diels-Alder reaction between 5-hydroxy-1,4-naphthoquinone and 5,5-dimethyl-3-vinyl-1,2-cyclohexadienyl acetate by endo addition gives the title compound, C22H22O5, in 68% yield. This racemic diastereoisomer has the opposite regiochemistry to ochromycinone analogues produced previously and may allow access to a new type of anticancer-active saquayamycin analogue.
U2 - 10.1107/S0108270103013374
DO - 10.1107/S0108270103013374
M3 - Article
VL - 59
SP - o431-o432
JO - Acta Crystallographica. Section C: Crystal Structure Communications
JF - Acta Crystallographica. Section C: Crystal Structure Communications
SN - 1600-5759
IS - 8
ER -