Understanding respiratory infections to improve vaccines

2022

Sleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies

Mateus, T., Seppanen, E. J., de Gier, C., Clark, S., Coates, H., Vijayasekaran, S., Prosser, K., Wiertsema, S. P., Fuery, A., Kirkham, L. A. S., Richmond, P. C. & Thornton, R. B., 28 Feb 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 831887.

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1 Citation (Scopus)

2021

Differences in Pneumococcal and Haemophilus influenzae Natural Antibody Development in Papua New Guinean Children in the First Year of Life

10v13v PCV Trial Team, Martinovich, K. M., Rahman, T., de Gier, C., Seppanen, E. J., Orami, T., Granland, C. M., Francis, J., Yoannes, M., Corscadden, K. J., Ford, R., Jacoby, P., van den Biggelaar, A. H. J., Bakaletz, L. O., Cripps, A. W., Lehmann, D., Richmond, P. C., Pomat, W. S., Kirkham, L. A. S. & Thornton, R. B., 10 Aug 2021, In: Frontiers in Immunology. 12, 725244.

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3 Citations (Scopus)

PCV10 elicits Protein D IgG responses in Papua New Guinean children but has no impact on NTHi carriage in the first two years of life

Rahman, T., de Gier, C., Orami, T., Seppanen, E. J., Granland, C. M., Francis, J. P., Michael, A., Yoannes, M., Corscadden, K. J., Ford, R. L., Martinovich, K. M., Jacoby, P., van den Biggelaar, A. H. J., Lehmann, D., Richmond, P. C., Pomat, W. S., Thornton, R. B. & Kirkham, L. A. S., 11 Jun 2021, In: Vaccine. 39, 26, p. 3486-3492 7 p.

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Open Access

3 Citations (Scopus)

2020

Nasal delivery of a commensal pasteurellaceae species inhibits nontypeable haemophilus influenzae colonization and delays onset of otitis media in mice

Granland, C. M., Scott, N. M., Lauzon-Joset, J. F., Langereis, J. D., De Gier, C., Sutherland, K. M. J., Clark, S. L., Pickering, J. L., Thornton, R. B., Richmond, P. C., Strickland, D. H. & Kirkhama, L. A. S., 1 Mar 2020, In: Infection and Immunity. 88, 4, e00685-19.

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Open Access

4 Citations (Scopus)

2019

Immunogenicity and immune memory after a pneumococcal polysaccharide vaccine booster in a high-risk population primed with 10-valent or 13-valent pneumococcal conjugate vaccine: A randomized controlled trial in Papua New Guinean children

van den Biggelaar, A. H. J., Pomat, W. S., Masiria, G., Wana, S., Nivio, B., Francis, J., Ford, R., Passey, M., Kirkham, L. A., Jacoby, P., Lehmann, D. & Richmond, P., 4 Feb 2019, In: Vaccines. 7, 1, 14 p., 17.

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Open Access

3 Citations (Scopus)

PCV7- and PCV10-Vaccinated Otitis-Prone Children in New Zealand Have Similar Pneumococcal and Haemophilus influenzae Densities in Their Nasopharynx and Middle Ear

de Gier, C., Granland, C. M., Pickering, J. L., Walls, T., Bhuiyan, M., Mills, N., Richmond, P. C., Best, E. J., Thornton, R. B. & Kirkham, L-A. S., 31 Jan 2019, In: Vaccines. 7, 1, 14 p., 14.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (Scopus)

Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: A randomized controlled trial of 10-valent and 13-valent pneumococcal conjugate vaccine in Papua New Guinean infants

Pomat, W. S., Van Den Biggelaar, A. H. J., Wana, S., Francis, J. P., Solomon, V., Greenhill, A. R., Ford, R., Orami, T., Passey, M., Jacoby, P., Kirkham, L. A., Lehmann, D. & Richmond, P. C., 24 Apr 2019, In: Clinical Infectious Diseases. 68, 9, p. 1472-1481 10 p.

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Open Access

19 Citations (Scopus)

2018

Evidence of functional cell-mediated immune responses to nontypeable Haemophilus influenzae in otitis-prone children

Seppanen, E., Tan, D., Corscadden, K. J., Currie, A. J., Richmond, P. C., Thornton, R. B. & Kirkham, L-AS., 1 Apr 2018, In: PLoS One. 13, 4, e0193962.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Citations (Web of Science)

2017

Australian Aboriginal children with otitis media have reduced antibody titers to specific nontypeable Haemophilus influenzae vaccine antigens

Thornton, R. B., Kirkham, L. A. S., Corscadden, K. J., Wiertsema, S. P., Fuery, A., Jones, B. J., Coates, H. L., Vijayasekaran, S., Zhang, G., Keil, A. & Richmond, P. C., 1 Apr 2017, In: Clinical and Vaccine Immunology. 24, 4, 10 p., 00556-16.

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13 Citations (Web of Science)

329 Downloads (Pure)

Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea

Lehmann, D., Kirarock, W., van den Biggelaar, A. H. J., Passey, M., Jacoby, P., Saleu, G., Masiria, G., Nivio, B., Greenhill, A., Orami, T., Francis, J., Ford, R., Kirkham, L-A., Solomon, V., Richmond, P. C., Pomat, W. S. & 10v13v PCV Trial Team, 25 Dec 2017, In: Pneumonia. 9, 15 p., 20.

Research output: Contribution to journal › Article › peer-review

Open Access