The L-type calcium channel in cardiovascular health and disease

Hool, Livia (Investigator 01)

School of Human Sciences

10 Article
6 Review article
1 Editorial

10 results

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2025
Novel Peptide Therapeutics Targeting the L-Type Calcium Channel Prevent Hypertrophic Cardiomyopathy by Decreasing Mitochondrial Energetics
Er, T. S., Reinke, D., Francis, A. J., Solomon, T. M., Viola, H. M., Szappanos, H. C., Richworth, C. M., Jenkins, C., Camacho Londoño, J. E., Ponnuswamy, P., McFarlane, C., Van Petegem, F. & Hool, L. C., 2025, In: JACC: Basic to Translational Science. 10, 10, 101292.
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2 Link opens in a new tab Citations (Scopus)
2024
Reduced connexin-43 expression, slow conduction and repolarisation dispersion in a model of hypertrophic cardiomyopathy
Lim, S., Mangala, M. M., Holliday, M., Cserne Szappanos, H., Barratt-Ross, S., Li, S., Thorpe, J., Liang, W., Ranpura, G. N., Vandenberg, J. I., Semsarian, C., Hill, A. P. & Hool, L. C., Aug 2024, In: Disease models & mechanisms. 17, 8, 12 p., dmm050407.
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Open Access
5 Link opens in a new tab Citations (Web of Science)
2023
A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology
Viola, H. M., Richworth, C., Solomon, T., Chin, I. L., Szappanos, H. C., Sundararaj, S., Shishmarev, D., Casarotto, M. G., Choi, Y. S. & Hool, L. C., 3 Jan 2023, In: Communications Biology. 6, 1, 13 p., 4.
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Open Access
11 Link opens in a new tab Citations (Scopus)
Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy
Cserne Szappanos, H., Viola, H. M., Ito, D. W., Lim, S., Mangala, M., Holliday, M., Barratt Ross, S., Semsarian, C., Hill, A., Dixon, R. E. & Hool, L. C., Dec 2023, In: Scientific Reports. 13, 1, p. 11296 1 p., 11296.
Research output: Contribution to journal › Article › peer-review

Open Access
6 Link opens in a new tab Citations (Scopus)
Volume adaptation of neonatal cardiomyocyte spheroids in 3D stiffness gradient GelMA
Chin, I. L., Amos, S. E., Jeong, J. H., Hool, L., Hwang, Y. & Choi, Y. S., Jun 2023, In: Journal of Biomedical Materials Research Part A. 111, 6, p. 801-813 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
15 Link opens in a new tab Citations (Scopus)
2020
A dendronized polymer variant that facilitates safe delivery of a calcium channel antagonist to the heart
Viola, H. M., Shah, A. A., Kretzmann, J. A., Evans, C. W., Norret, M., Iyer, K. S. & Hool, L. C., Oct 2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 29, 102264.
Research output: Contribution to journal › Article › peer-review

Open Access
6 Link opens in a new tab Citations (Scopus)
Neuronal nitric oxide synthase regulation of calcium cycling in ventricular cardiomyocytes is independent of Ca_v1.2 channel modulation under basal conditions
Ebner, J., Cagalinec, M., Kubista, H., Todt, H., Szabo, P. L., Kiss, A., Podesser, B. K., Cserne Szappanos, H., Hool, L. C., Hilber, K. & Koenig, X., 1 Jan 2020, In: Pflugers Archiv European Journal of Physiology. 472, 1, p. 61-74 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
7 Link opens in a new tab Citations (Scopus)
2019
Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions
Olivé, M., Engvall, M., Ravenscroft, G., Cabrera-Serrano, M., Jiao, H., Bortolotti, C. A., Pignataro, M., Lambrughi, M., Jiang, H., Forrest, A. R. R., Benseny-Cases, N., Hofbauer, S., Obinger, C., Battistuzzi, G., Bellei, M., Borsari, M., Di Rocco, G., Viola, H. M., Hool, L. C. & Cladera, J. & 24 others, Lagerstedt-Robinson, K., Xiang, F., Wredenberg, A., Miralles, F., Baiges, J. J., Malfatti, E., Romero, N. B., Streichenberger, N., Vial, C., Claeys, K. G., Straathof, C. S. M., Goris, A., Freyer, C., Lammens, M., Bassez, G., Kere, J., Clemente, P., Sejersen, T., Udd, B., Vidal, N., Ferrer, I., Edström, L., Wedell, A. & Laing, N. G., 1 Dec 2019, In: Nature Communications. 10, 1, 1396.
Research output: Contribution to journal › Article › peer-review

Open Access
23 Link opens in a new tab Citations (Scopus)
TGF‐β‐induced fibrotic stress increases G‐quadruplex formation in human fibroblasts
Toshniwal, P., Nguyen, M., Guédin , A., Viola, H., Ho, D., Kim, Y., Bhatt, U., Bond, C. S., Hool, L., Hurley, L., Mergny, J.-L., Wood, F., Fear, M., Swaminatha Iyer, K. & Smith, N., 1 Nov 2019, In: FEBS Letters. 593, 22, p. 3149-3161 13 p.
Research output: Contribution to journal › Article › peer-review
10 Link opens in a new tab Citations (Scopus)
2018
A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery
Hoffmann, K., Milech, N., Juraja, S. M., Cunningham, P. T., Stone, S. R., Francis, R. W., Anastasas, M., Hall, C. M., Heinrich, T., Bogdawa, H. M., Winslow, S., Scobie, M. N., Dewhurst, R. E., Florez, L., Ong, F., Kerfoot, M., Champain, D., Adams, A. M., Fletcher, S. & Viola, H. M. & 10 others, Hool, L. C., Connor, T., Longville, B. A. C., Tan, Y. F., Kroeger, K., Morath, V., Weiss, G. A., Skerra, A., Hopkins, R. M. & Watt, P. M., 1 Dec 2018, In: Scientific Reports. 8, 1, 12538.
Research output: Contribution to journal › Article › peer-review

Open Access
52 Link opens in a new tab Citations (Scopus)

The L-type calcium channel in cardiovascular health and disease

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