STAT3 Regulation of Cell Responses in IPF

Prele, Cecilia (Investigator 01)
Mutsaers, Steve (Investigator 02)
Knight, Darryl (Investigator 03)
O'Donoghue, Robert (Investigator 04)
Hoyne, Gerard (Investigator 05)
Laurent, Geoff (Investigator 06)

Status	Finished
Effective start/end date	1/01/14 → 31/12/17

Funding

NHMRC National Health and Medical Research Council : A$661,563.00

Access Project

http://purl.org/au-research/grants/nhmrc/1067511

2 Article

Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis
Prêle, C. M., Miles, T., Pearce, D. R., O'Donoghue, R. J., Grainge, C., Barrett, L., Birnie, K., Lucas, A. D., Baltic, S., Ernst, M., Rinaldi, C., Laurent, G. J., Knight, D. A., Fear, M., Hoyne, G., McAnulty, R. J. & Mutsaers, S. E., 1 Nov 2022, In: The European Respiratory Journal. 60, 5, 2101469.
Research output: Contribution to journal › Article › peer-review

Open Access
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40 Citations (Scopus)

73 Downloads (Pure)
PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production
Celada, L. J., Kropski, J. A., Herazo-Maya, J. D., Luo, W., Creecy, A., Abad, A. T., Chioma, O. S., Lee, G., Hassell, N. E., Shaginurova, G. I., Wang, Y., Johnson, J. E., Kerrigan, A., Mason, W. R., Baughman, R. P., Ayers, G. D., Bernard, G. R., Culver, D. A., Montgomery, C. G. & Maher, T. M. & 10 others, Molyneaux, P. L., Noth, I., Mutsaers, S. E., Prele, C. M., Stokes Peebles, R., Newcomb, D. C., Kaminski, N., Blackwell, T. S., Van Kaer, L. & Drake, W. P., 26 Sept 2018, In: Science Translational Medicine. 10, 460, 15 p., eaar8356.
Research output: Contribution to journal › Article › peer-review

Open Access
280 Citations (Scopus)