Repair of Epigenetic Abnormalities in Human Induced Pluripotent Stem Cells by Targeted Epigenome Engineering

Project Details

StatusFinished
Effective start/end date1/01/1431/12/16

Funding

  • National Health & Medical Research Council NHMRC: A$265,952.00
  • National Health & Medical Research Council NHMRC: A$248,438.00
  • National Health & Medical Research Council NHMRC: A$269,274.00
  • Modelling human blastocysts by reprogramming fibroblasts into iBlastoids

    Liu, X., Tan, J. P., Schröder, J., Aberkane, A., Ouyang, J. F., Mohenska, M., Lim, S. M., Sun, Y. B. Y., Chen, J., Sun, G., Zhou, Y., Poppe, D., Lister, R., Clark, A. T., Rackham, O. J. L., Zenker, J. & Polo, J. M., 25 Mar 2021, In: Nature. 591, 7851, p. 627-632 6 p.

    Research output: Contribution to journalArticlepeer-review

    99 Citations (Scopus)
  • Reprogramming roadmap reveals route to human induced trophoblast stem cells

    Liu, X., Ouyang, J. F., Rossello, F. J., Tan, J. P., Davidson, K. C., Valdes, D. S., Schröder, J., Sun, Y. B. Y., Chen, J., Knaupp, A. S., Sun, G., Chy, H. S., Huang, Z., Pflueger, J., Firas, J., Tano, V., Buckberry, S., Paynter, J. M., Larcombe, M. R., Poppe, D., & 19 othersChoo, X. Y., O’Brien, C. M., Pastor, W. A., Chen, D., Leichter, A. L., Naeem, H., Tripathi, P., Das, P. P., Grubman, A., Powell, D. R., Laslett, A. L., David, L., Nilsson, S. K., Clark, A. T., Lister, R., Nefzger, C. M., Martelotto, L. G., Rackham, O. J. L. & Polo, J. M., 1 Oct 2020, In: Nature. 586, 7827, p. 101-107 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    60 Citations (Scopus)
    73 Downloads (Pure)
  • TINC— A Method to Dissect Regulatory Complexes at Single-Locus Resolution— Reveals an Extensive Protein Complex at the Nanog Promoter

    Knaupp, A. S., Mohenska, M., Larcombe, M. R., Ford, E., Lim, S. M., Wong, K., Chen, J., Firas, J., Huang, C., Liu, X., Nguyen, T., Sun, Y. B. Y., Holmes, M. L., Tripathi, P., Pflueger, J., Rossello, F. J., Schröder, J., Davidson, K. C., Nefzger, C. M., Das, P. P., & 4 othersHaigh, J. J., Lister, R., Schittenhelm, R. B. & Polo, J. M., 8 Dec 2020, In: Stem Cell Reports. 15, 6, p. 1246-1259 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Citations (Scopus)