Repair of Epigenetic Abnormalities in Human Induced Pluripotent Stem Cells by Targeted Epigenome Engineering

Lister, Ryan (Chief Investigator)
Polo, Jose (Investigator 02)
Swaminatha Iyer, Killugudi (Investigator 03)
Blancafort, Pilar (Investigator 04)

Project Details

Status	Finished
Effective start/end date	1/01/14 → 31/12/16

Funding

National Health & Medical Research Council NHMRC: AUD265,952.00
National Health & Medical Research Council NHMRC: AUD248,438.00
National Health & Medical Research Council NHMRC: AUD269,274.00

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Access Project

http://purl.org/au-research/grants/nhmrc/1069830

3 Article

Reprogramming roadmap reveals route to human induced trophoblast stem cells
Liu, X., Ouyang, J. F., Rossello, F. J., Tan, J. P., Davidson, K. C., Valdes, D. S., Schröder, J., Sun, Y. B. Y., Chen, J., Knaupp, A. S., Sun, G., Chy, H. S., Huang, Z., Pflueger, J., Firas, J., Tano, V., Buckberry, S., Paynter, J. M., Larcombe, M. R., Poppe, D. & 19 others, Choo, X. Y., O’Brien, C. M., Pastor, W. A., Chen, D., Leichter, A. L., Naeem, H., Tripathi, P., Das, P. P., Grubman, A., Powell, D. R., Laslett, A. L., David, L., Nilsson, S. K., Clark, A. T., Lister, R., Nefzger, C. M., Martelotto, L. G., Rackham, O. J. L. & Polo, J. M., 1 Oct 2020, In : Nature. 586, 7827, p. 101-107
Research output: Contribution to journal › Article
1 Citation (Scopus)
TINC— A Method to Dissect Regulatory Complexes at Single-Locus Resolution— Reveals an Extensive Protein Complex at the Nanog Promoter
Knaupp, A. S., Mohenska, M., Larcombe, M. R., Ford, E., Lim, S. M., Wong, K., Chen, J., Firas, J., Huang, C., Liu, X., Nguyen, T., Sun, Y. B. Y., Holmes, M. L., Tripathi, P., Pflueger, J., Rossello, F. J., Schröder, J., Davidson, K. C., Nefzger, C. M., Das, P. P. & 4 others, Haigh, J. J., Lister, R., Schittenhelm, R. B. & Polo, J. M., 8 Dec 2020, In : Stem Cell Reports. 15, 6, p. 1246-1259 14 p.
Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming
Liu, X., Nefzger, C. M., Rossello, F. J., Chen, J., Knaupp, A. S., Firas, J., Ford, E., Pflueger, J., Paynter, J. M., Chy, H. S., O'Brien, C. M., Huang, C., Mishra, K., Hodgson-Garms, M., Jansz, N., Williams, S. M., Blewitt, M. E., Nilsson, S. K., Schittenhelm, R. B., Laslett, A. L. & 2 others, Lister, R. & Polo, J. M., Nov 2017, In : Nature Methods. 14, 11, p. 1055-1062
Research output: Contribution to journal › Article

45 Citations (Scopus)

Repair of Epigenetic Abnormalities in Human Induced Pluripotent Stem Cells by Targeted Epigenome Engineering

Funding

Access Project

Reprogramming roadmap reveals route to human induced trophoblast stem cells

TINC— A Method to Dissect Regulatory Complexes at Single-Locus Resolution— Reveals an Extensive Protein Complex at the Nanog Promoter

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming