Repair of Epigenetic Abnormalities in Human Induced Pluripotent Stem Cells by Targeted Epigenome Engineering

Status	Finished
Effective start/end date	1/01/14 → 31/12/16

Access Project

Transient naive reprogramming corrects hiPS cells functionally and epigenetically
Buckberry, S., Liu, X., Poppe, D., Tan, J. P., Sun, G., Chen, J., Nguyen, T. V., de Mendoza Soler, A., Pflueger, J., Frazer, T., Vargas Landin, D., Paynter, J. M., Smits, N., Liu, N., Ouyang, J. F., Rossello, F. J., Chy, H. S., Rackham, O. J. L., Laslett, A. L. & Breen, J. & 4 others, Faulkner, G. J., Nefzger, C. M., Polo, J. M. & Lister, R., 24 Aug 2023, In: Nature. 620, 7975, p. 863-872 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
33 Citations (Scopus)
Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability
de Mendoza, A., Nguyen, T. V., Ford, E., Poppe, D., Buckberry, S., Pflueger, J., Grimmer, M. R., Stolzenburg, S., Bogdanovic, O., Oshlack, A., Farnham, P. J., Blancafort, P. & Lister, R., Dec 2022, In: Genome Biology. 23, 1, p. 1-31 32 p., 163.
Research output: Contribution to journal › Article › peer-review

Open Access
53 Citations (Web of Science)
Modelling human blastocysts by reprogramming fibroblasts into iBlastoids
Liu, X., Tan, J. P., Schröder, J., Aberkane, A., Ouyang, J. F., Mohenska, M., Lim, S. M., Sun, Y. B. Y., Chen, J., Sun, G., Zhou, Y., Poppe, D., Lister, R., Clark, A. T., Rackham, O. J. L., Zenker, J. & Polo, J. M., 25 Mar 2021, In: Nature. 591, 7851, p. 627-632 6 p.
Research output: Contribution to journal › Article › peer-review
248 Citations (Scopus)