Discovery of Single Agents to Treat Chagas Disease and Human African Trypanosomiasis

Baell, Jonathan (Investigator 01)
Avery, Vicky (Investigator 02)
Charman, Susan (Investigator 03)
Creek, Darren (Investigator 04)
Piggott, Matthew (Investigator 05)

School of Molecular Sciences

Status	Finished
Effective start/end date	1/01/15 → 31/12/17

Funding

NHMRC National Health and Medical Research Council : A$24,000.00

2 Article

Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi
Varghese, S., Rahmani, R., Russell, S., Deora, G. S., Ferrins, L., Toynton, A., Jones, A., Sykes, M., Kessler, A., Eufrásio, A., Cordeiro, A. T., Sherman, J., Rodriguez, A., Avery, V. M., Piggott, M. J. & Baell, J. B., Mar 2020, In: ACS Medicinal Chemistry Letters. 11, 3, p. 278-285 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
17 Citations (Scopus)
Hit-to-lead optimization of a novel class of potent, broad-spectrum trypanosomacides
Russell, S., Rahmani, R., Jones, A. J., Newson, H., Neilde, K., Cotillo, I., Khajouei, M., Ferrins, L., Qureishi, S., Nguyen, N., Martinez-Martinez, M. S., Weaver, D. F., Kaiser, M., Riley, J., Thomas, J., De Rycker, M., Read, K. D., Flematti, G., Ryan, E. & Tanghe, S. & 6 others, Rodriguez, A., Charman, S. A., Kessler, A., Avery, V. M., Baell, J. B. & Piggott, M., 10 Nov 2016, In: Journal of Medicinal Chemistry. 59, 21, p. 9686-9720 35 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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36 Citations (Scopus)

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