Designing new therapeutics using medical synthetic biology

Status	Curtailed
Effective start/end date	1/01/19 → 9/10/20

Access Project

Hyperactive Nickase Activity Improves Adenine Base Editing
Gandadireja, A. P., Vos, P. D., Siira, S. J., Filipovska, A. & Rackham, O., 18 Oct 2024, In: ACS Synthetic Biology. 13, 10, p. 3128-3136 9 p.
Research output: Contribution to journal › Article › peer-review
Mutational rescue of the activity of high-fidelity Cas9 enzymes
Vos, P. D., Gandadireja, A. P., Rossetti, G., Siira, S. J., Mantegna, J. L., Filipovska, A. & Rackham, O., 22 Apr 2024, In: Cell Reports Methods. 4, 4, 13 p., 100756.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Citations (Scopus)
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription
Dai, C. Y., Ng, C. C., Hung, G. C. C., Kirmes, I., Hughes, L. A., Du, Y., Brosnan, C. A., Ahier, A., Hahn, A., Haynes, C. M., Rackham, O., Filipovska, A. & Zuryn, S., 17 Jul 2023, In: Nature Cell Biology. 25, 8, p. 1111-1120 10 p.
Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)