Cancer Chemo Immunotherapy - Exploiting the Immunogenic Momentum of Cytotoxic Chemotherapy

Lake, Richard (Chief Investigator)
Lesterhuis, Willem (Investigator 02)
Khong, Andrea (Investigator 03)
Nowak, Anna (Investigator 04)
Robinson, Bruce (Investigator 05)

Status	Finished
Effective start/end date	1/01/14 → 31/12/17

Funding

National Health & Medical Research Council NHMRC: A$886,226.00

Access Project

http://purl.org/au-research/grants/nhmrc/1067113

3 Article

Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations
Principe, N., Aston, W. J., Hope, D. E., Tilsed, C. M., Fisher, S. A., Boon, L., Dick, I. M., Chin, W. L., McDonnell, A. M., Nowak, A. K., Lake, R. A., Chee, J. & Lesterhuis, W. J., 11 May 2022, In: Frontiers in Immunology. 13, 872295.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Citation (Scopus)
Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment
Aston, W. J., Hope, D. E., Cook, A. M., Boon, L., Dick, I., Nowak, A. K., Lake, R. A. & Lesterhuis, W. J., 2 Nov 2019, In: OncoImmunology. 8, 11, 8 p., e1641390.
Research output: Contribution to journal › Article › peer-review

Open Access
17 Citations (Scopus)
Direct inhibition of STAT signaling by platinum drugs contributes to their anti-cancer activity
Hato, S. V., Figdor, C. G., Takahashi, S., Pen, A. E., Halilovic, A., Bol, K. F., Vasaturo, A., Inoue, Y., Haas, N. D., Verweij, D., Van Herpen, C. M. L., Kaanders, J. H., van Krieken, J. H. J. M., Van Laarhoven, H. W. M., Hooijer, G. K. J., Punt, C. J. A., Asai, A., de Vries, I. J. M. & Lesterhuis, W. J., 1 Jan 2017, In: Oncotarget. 8, 33, p. 54434-54443 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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12 Citations (Scopus)

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