Zhuo (Alex) Shang


  • The University of Western Australia (M720), 35 Stirling Highway,

    6009 Perth


Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile


My current research at University of Western Australia is focused on the discovery and ecological functions of ribosomally synthesized and post-translationally modified peptide (RiPPs) from Australian fungi. Before moving to University of Western Australia in 2020, I took postdoctoral positions at Scripps Institution of Oceanography/University of California San Diego, The Rockefeller University, and University of South Carolina, where I discovered novel, biologically active peptides (e.g. cadasides, salinipeptins, myxomapeptins) from marine bacteria, soil metagenomes, and human tumor-associated bacteria using integrated (meta)genomics, synthetic biology, and chemical approaches. During 2008-2016, I was professionally trained in the field of natural products chemistry and microbiology during my postgraduate study in Chinese Academy of Sciences and The University of Queensland, where my projects directed at the identification and diversification of marine fungal natural products for the treatment of infections and cancers.

My expertise includes purification and structure characterization of complex natural products, isolation and cultivation of microbes, bioinformatic analysis and heterologous expression of microbial biosynthetic gene clusters as well as bioassay screenings. Apart from natural products-based drug discovery, my research has also expanded to biosynthesis of microbial natural products, engineering of microbial biosynthetic pathways, and antibiotic mechanism of action study.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water

Education/Academic qualification

Marine Natural Product Chemistry, PhD, Unveiling the chemical diversity of marine intertidal fungal communities, University of Queensland

1 Apr 201220 Jun 2016

Award Date: 20 Jun 2016

Industry keywords

  • Drug Discovery
  • Biotechnology

Research expertise keywords

  • Natural product chemistry
  • Antibiotics
  • Secondary metabolite biosynthesis
  • Peptides
  • Synthetic biology


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Collaborations and top research areas from the last five years

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