Yuben Moodley

Associate Professor, MB BS MD Natal , PhD W.Aust. , FRACP

  • The University of Western Australia (M582), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1812 Citations
  • 20 h-Index
20012022
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Research Output 2001 2019

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Article
2019

A standardised protocol for the evaluation of small extracellular vesicles in plasma by imaging flow cytometry

Armitage, J. D., Tan, D. B. A., Cha, L., Clark, M., Gray, E. S., Fuller, K. A. & Moodley, Y. P., 1 May 2019, In : Journal of Immunological Methods. 468, p. 61-66 6 p.

Research output: Contribution to journalArticle

Flow Cytometry
Lighting
Extracellular Vesicles
Idiopathic Pulmonary Fibrosis
Cell Aging
Genes
Alleles
Genome-Wide Association Study
2018
1 Citation (Scopus)

Diagnosis and management of idiopathic pulmonary fibrosis: Thoracic society of Australia and New Zealand and lung foundation australia position statements summary

Jo, H. E., Prasad, J. D., Troy, L. K., Mahar, A., Bleasel, J., Ellis, S. J., Chambers, D. C., Holland, A. E., Lake, F. R., Keir, G., Goh, N. S., Wilsher, M., de Boer, S., Moodley, Y., Grainge, C., Whitford, H. M., Chapman, S. A., Reynolds, P. N., Beatson, D., Jones, L. J. & 4 othersHopkins, P., Allan, H. M., Glaspole, I. & Corte, T. J., 5 Feb 2018, In : Medical Journal of Australia. 208, 2, p. 82-88 7 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
New Zealand
Thorax
Lung
Interstitial Lung Diseases
4 Citations (Scopus)

Disease progression in idiopathic pulmonary fibrosis with mild physiological impairment: Analysis from the Australian IPF registry

Jo, H. E., Glaspole, I., Moodley, Y., Chapman, S., Ellis, S., Goh, N., Hopkins, P., Keir, G., Mahar, A., Cooper, W., Reynolds, P., Haydn Walters, E., Zappala, C., Grainge, C., Allan, H., Macansh, S. & Corte, T. J., 25 Jan 2018, In : BMC Pulmonary Medicine. 18, 1, 19.

Research output: Contribution to journalArticle

Open Access
Idiopathic Pulmonary Fibrosis
Registries
Disease Progression
Lung Diseases
Survival
2 Citations (Scopus)

Epithelial disruption: A new paradigm enabling human airway stem cell transplantation

Farrow, N., Cmielewski, P., Donnelley, M., Rout-Pitt, N., Moodley, Y., Bertoncello, I. & Parsons, D., 13 Jun 2018, In : Stem Cell Research and Therapy. 9, 1, 153.

Research output: Contribution to journalArticle

Open Access
Stem Cell Transplantation
Stem cells
Transplantation
Luciferases
Cystic Fibrosis
2017
19 Citations (Scopus)

Baseline characteristics of idiopathic pulmonary fibrosis: analysis from the Australian Idiopathic Pulmonary Fibrosis Registry

Jo, H. E., Glaspole, I., Grainge, C., Goh, N., Hopkins, P. M. A., Moodley, Y., Reynolds, P. N., Chapman, S., Walters, E. H., Zappala, C., Allan, H., Keir, G. J., Hayen, A., Cooper, W. A., Mahar, A. M., Ellis, S., Macansh, S. & Corte, T. J., Feb 2017, In : The European Respiratory Journal. 49, 2, 1601592.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Registries
Mortality
Lung Volume Measurements
Cohort Effect
7 Citations (Scopus)

Elevated levels of circulating exosome in COPD patients are associated with systemic inflammation

Tan, D. B. A., Armitage, J., Teo, T. H., Ong, N. E., Shin, H. & Moodley, Y. P., Nov 2017, In : Respiratory Medicine. 132, p. 261-264

Research output: Contribution to journalArticle

Exosomes
Chronic Obstructive Pulmonary Disease
Inflammation
Tumor Necrosis Factor Receptors
C-Reactive Protein
18 Citations (Scopus)

Health-related quality of life in idiopathic pulmonary fibrosis: Data from the Australian IPF Registry

Glaspole, I. N., Chapman, S. A., Cooper, W. A., Ellis, S. J., Goh, N. S., Hopkins, P. M., Macansh, S., Mahar, A., Moodley, Y. P., Paul, E., Reynolds, P. N., Walters, E. H., Zappala, C. J. & Corte, T. J., Jul 2017, In : Respirology. 22, 5, p. 950-956

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Registries
Quality of Life
Dyspnea
Linear Models
3 Citations (Scopus)

Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease

Tan, D., Teo, T. H., Setiawan, A. M., Ong, N., Zimmermann, M., Price, P., Kirkham, L. A. S. & Moodley, Y. P., Jun 2017, In : Immunology. 151, 2, p. 219-226

Research output: Contribution to journalArticle

CTLA-4 Antigen
Chronic Obstructive Pulmonary Disease
T-Lymphocytes
Regulatory T-Lymphocytes
Blood Cells
8 Citations (Scopus)
2016
2 Citations (Scopus)

An evaluation of CD39 as a novel immunoregulatory mechanism invoked by COPD

Tan, D., Ong, N. E., Zimmermann, M., Price, P. & Moodley, Y., 2016, In : Human Immunology. 77, 10, p. 916-920

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
T-Lymphocytes
Histocompatibility
Tumor Necrosis Factor Receptors
Virus Diseases
13 Citations (Scopus)

Evaluating the interstitial lung disease multidisciplinary meeting: A survey of expert centres

Jo, H. E., Corte, T. J., Moodley, Y., Levin, K., Westall, G., Hopkins, P., Chambers, D. & Glaspole, I., 2016, In : BMC Pulmonary Medicine. 16, 1, 22.

Research output: Contribution to journalArticle

Open Access
Interstitial Lung Diseases
Constitution and Bylaws
North America
Documentation
Internet
10 Citations (Scopus)

Human mesenchymal stem cells attenuate early damage in a ventilated pig model of acute lung injury

Moodley, Y., Sturm, M., Shaw, K., Shimbori, C., Tan, D., Kolb, M. & Graham, R., 2016, In : Stem Cell Research. 17, 1, p. 25-31

Research output: Contribution to journalArticle

Open Access
Acute Lung Injury
Mesenchymal Stromal Cells
Swine
Oleic Acid
Adult Respiratory Distress Syndrome
9 Citations (Scopus)

Idiopathic Pulmonary Fibrosis and the Elderly: Diagnosis and Management Considerations

Jo, H. E., Randhawa, S., Corte, T. J. & Moodley, Y., 2016, In : Drugs and Aging. 33, 5, p. 1-14

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Morbidity
Biopsy
Polypharmacy
Terminal Care
1 Citation (Scopus)

Integrated Multidisciplinary Community Service for Chronic Obstructive Pulmonary Disease Reduces Hospitalisations

Chung, L. P., Lake, F., Hyde, E., Mccamley, C., Phuangmalai, N., Lim, M., Waterer, G., Summers, Q. & Moodley, Y., 2016, In : Internal Medicine Journal. 46, 4, p. 427-434

Research output: Contribution to journalArticle

2015
35 Citations (Scopus)
Nitrates
Randomized Controlled Trials
Blood Pressure
Nitrites
Placebos
6 Citations (Scopus)

Do all patients with idiopathic pulmonary fibrosis warrant a trial of therapeutic intervention? A pro-con perspective

Moodley, Y., Corte, T. J., Richeldi, L. & King, T. E., 2015, In : Respirology. 20, 3, p. 389-394

Research output: Contribution to journalArticle

Open Access
Idiopathic Pulmonary Fibrosis
Pulmonary Fibrosis
Therapeutics
Safety
Gases
2014
8 Citations (Scopus)

A pilot study of a mobile-phone-based home monitoring system to assist in remote interventions in cases of acute exacerbation of COPD

Ding, H., Karunanithi, M., Kanagasingam, Y., Vignarajan, J. & Moodley, Y., 2014, In : Journal of Telemedicine and Telecare. 20, 3, p. 128-134

Research output: Contribution to journalArticle

18 Citations (Scopus)

Australian idiopathic pulmonary fibrosis registry: Vital lessons from a national prospective collaborative project

Moodley, Y., Goh, N., Glaspole, I. N., Macansh, S., Haydn Walters, E., Chapman, S. A., Hopkins, P. M. A., Reynolds, P. N., Zappala, C. J., Cooper, W., Mahar, A. M., Ellis, S. J., Mccormack, S., Darbishire, W., Wood-Baker, R. R. & Corte, T. J., 2014, In : Respirology. 19, 7, p. 1088-1091

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Registries
Research
4 Citations (Scopus)

Impaired CTLA-4 responses in COPD are associated with systemic inflammation

Tan, D., Fernández, S., Price, P., French, M., Thompson, P. J. & Moodley, Y., 2014, In : Cellular and Molecular Immunology. 11, 6, p. 606-608

Research output: Contribution to journalArticle

15 Citations (Scopus)
Regulatory T-Lymphocytes
Chronic Obstructive Pulmonary Disease
T-Lymphocytes
Blood Cells
Body Mass Index
32 Citations (Scopus)

Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis

Royce, S. G., Moodley, Y. & Samuel, C. S., Mar 2014, In : Pharmacology & Therapeutics. 141, 3, p. 250-260 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
Inflammation
Blood Cells
Myeloid-Derived Suppressor Cells
Cytokines
2013
54 Citations (Scopus)

Anti-Inflammatory Effects of Adult Stem Cells in Sustained Lung Injury: A Comparative Study

Moodley, Y., Vaghjiani, V., Chan, J., Baltić, S., Ryan, M., Tchongue, J., Samuel, C. S., Murthi, P., Parolini, O. & Manuelpillai, U., 2013, In : PLoS One. 8, 8, p. e69299

Research output: Contribution to journalArticle

Open Access
Adult Stem Cells
Amnion
Lung Injury
Stem cells
anti-inflammatory activity
56 Citations (Scopus)

Introduction to stem cells and regenerative medicine

Kolios, G. & Moodley, Y., 2013, In : Respiration. 2013, 85, p. 3-10

Research output: Contribution to journalArticle

2011
96 Citations (Scopus)

Amniotic membrane and amniotic cells: Potential therapeutic tools to combat tissue inflammation and fibrosis?

Manuelpillai, U., Moodley, Y., Borlongan, C. V. & Parolini, O., 2011, In : Placenta. 32, p. S320-325

Research output: Contribution to journalArticle

38 Citations (Scopus)

Cellular therapies for lung disease: a distant horizon

Moodley, Y., Manuelpillai, U. & Weiss, DJ., 2011, In : Respirology. 16, 2, p. 223-237

Research output: Contribution to journalArticle

Open Access
2010
119 Citations (Scopus)

Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair.

Moodley, Y., Ilancheran, S., Samuel, C., Vaghjiani, V., Atienza, D., Williams, E. D., Jenkin, G., Wallace, E., Trounson, A. & Manuelpillai, U., 2010, In : American Journal of Respiratory and Critical Care Medicine. 182, 5, p. 643-651

Research output: Contribution to journalArticle

53 Citations (Scopus)
2009
200 Citations (Scopus)

Human umbilical cord mesenchymal stem cells reduce fibrosis of bleomycin-induced lung injury

Moodley, Y., Atienza, D., Manuelpillai, U., Samuel, CS., Tchongue, J., Ilancheran, S., Boyd, R. & Trounson, A., 2009, In : American Journal of Pathology. 175, 1, p. 303-313

Research output: Contribution to journalArticle

196 Citations (Scopus)

The Peopling of the Pacific from a Bacterial Perspective

Moodley, Y., Linz, B., Yamaoka, Y., Windsor, H., Breurec, S., Wu, J-Y., Maady, A., Bernhoft, S., Thiberge, J-M., Phuanukoonon, S., Jobb, G., Siba, P., Graham, D. Y., Marshall, B. & Achtman, M., 2009, In : Science. 323, 5913, p. 527-530

Research output: Contribution to journalArticle

Melanesia
New Guinea
Helicobacter pylori
Language
Polynesia
2004
73 Citations (Scopus)

Comparison of the morphological and biochemical changes in normal human lung fibroblasts and fibroblasts derived from lungs of patients with idiopathic pulmonary fibrosis during FasL-induced apoptosis

Moodley, Y. P., Caterina, P., Scaffidi, A. K., Misso, N., Papadimitriou, J., Mcanulty, R. J., Laurent, G. J., Thompson, P. & Knight, D. A., 2004, In : Journal of Pathology. 202, 4, p. 486-495

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Fibroblasts
Apoptosis
Lung
Caspase 3
83 Citations (Scopus)

αvβ3 Integrin Interacts with the Transforming Growth Factor β (TGFβ) Type II Receptor to Potentiate the Proliferative Effects of TGFβ1 in Living Human Lung Fibroblasts

Scaffidi, A. K., Petrovic, N., Moodley, Y. P., Fogel-Petrovic, M., Kroeger, K. M., Seeber, R. M., Eidne, K. A., Thompson, P. & Knight, D. A., 2004, In : Journal of Biological Chemistry. 279, 36, p. 37726-37733

Research output: Contribution to journalArticle

Bioluminescence
Tenascin
Energy Transfer
Transforming Growth Factors
Fibroblasts
2003
85 Citations (Scopus)

Fibroblasts Isolated from Normal Lungs and Those with Idiopathic Pulmonary Fibrosis Differ in Interleukin-6/gp 130-Medicated Cell Signaling and Proliferation

Moodley, Y. P., Scaffidi, A. K., Misso, N., Keerthisingam, C., Mcanulty, R. J., Lauren, G. J., Mutsaers, S. E., Thompson, P. & Knight D.a., N. V., 2003, In : American Journal of Pathology. 163, 1, p. 345-354

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Interleukin-6
Fibroblasts
Cell Proliferation
Lung
97 Citations (Scopus)

Inverse Effects of Interleukin-6 on Apoptosis of Fibroblasts from Pulmonary Fibrosis and Normal Lungs

Moodley, Y. P., Misso, N., Scaffidi, A. K., Fogel-Petrovic, M., Mcanulty, R. J., Laurent, G. J., Thompson, P. & Knight, D. A., 2003, In : American Journal of Respiratory Cell and Molecular Biology. 29, 4, p. 490-498

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Pulmonary Fibrosis
Fibroblasts
Interleukin-6
Apoptosis
75 Citations (Scopus)

Macrophage recognition and phagocytosis of apoptotic fibroblasts is critically dependent on fibroblast-derived thrombospondin 1 and CD36

Moodley, Y., Rigby, P., Bundell, C., Bunt, S., Hayashi, H., Misso, N., Mcanulty, R., Laurent, G., Scaffidi, A., Thompson, P. & Knight, D., 2003, In : American Journal of Pathology. 162, 3, p. 177-179

Research output: Contribution to journalArticle

Thrombospondin 1
Phagocytosis
Fibroblasts
Macrophages
Phagocytes
37 Citations (Scopus)
2002
72 Citations (Scopus)

Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts

Scaffidi, A. K., Mutsaers, S. E., Moodley, Y. P., Mcanulty, R. J., Laurent, G. J., Thompson, P. & Knight Da, N. V., 2002, In : British Journal of Pharmacology. 136, p. 793-801

Research output: Contribution to journalArticle

Oncostatin M
Collagen
Fibroblasts
Apoptosis
Lung
2001
55 Citations (Scopus)

Regulation of human lung fibroblast phenotype and function by vitronectin and vitronectin integrins

Scaffidi, A. K., Moodley, Y. P., Weichselbaum, M., Thompson, P. & Knight, D. A., 2001, In : Journal of Cell Science. 114, 19, p. 3507-3516

Research output: Contribution to journalArticle

Vitronectin
Integrins
Smooth Muscle
Actins
Fibroblasts