Yuben Moodley

Associate Professor, MB BS MD Natal , PhD W.Aust. , FRACP

  • The University of Western Australia (M582), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1999 Citations
  • 22 h-Index
20012021
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Research Output 2001 2020

41 Citations (Scopus)
Nitrates
Randomized Controlled Trials
Blood Pressure
Nitrites
Placebos
1 Citation (Scopus)

A high COPD assessment test score may predict anxiety in COPD

Harryanto, H., Burrows, S. & Moodley, Y., 21 Mar 2018, In : International Journal of COPD. 13, p. 955-957 3 p.

Research output: Contribution to journalLetter

Open Access
103 Citations (Scopus)

Amniotic membrane and amniotic cells: Potential therapeutic tools to combat tissue inflammation and fibrosis?

Manuelpillai, U., Moodley, Y., Borlongan, C. V. & Parolini, O., 2011, In : Placenta. 32, p. S320-325

Research output: Contribution to journalArticle

1 Citation (Scopus)

An alternative approach to the current diagnostic guidelines for fibrotic interstitial lung disease

Moodley, Y., 1 Jun 2018, In : Respirology. 23, 6, p. 564-566 3 p.

Research output: Contribution to journalComment/debate

Open Access
1 Citation (Scopus)

Analysis by proteomics reveals unique circulatory proteins in idiopathic pulmonary fibrosis

Moodley, Y. P., Corte, T. J., Oliver, B. G., Glaspole, I. N., Livk, A., Ito, J., Peters, K., Lipscombe, R., Casey, T. & Tan, D. B. A., 8 Aug 2019, In : Respirology. 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

An evaluation of CD39 as a novel immunoregulatory mechanism invoked by COPD

Tan, D., Ong, N. E., Zimmermann, M., Price, P. & Moodley, Y., 2016, In : Human Immunology. 77, 10, p. 916-920

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
T-Lymphocytes
Histocompatibility
Tumor Necrosis Factor Receptors
Virus Diseases
57 Citations (Scopus)

Anti-Inflammatory Effects of Adult Stem Cells in Sustained Lung Injury: A Comparative Study

Moodley, Y., Vaghjiani, V., Chan, J., Baltić, S., Ryan, M., Tchongue, J., Samuel, C. S., Murthi, P., Parolini, O. & Manuelpillai, U., 2013, In : PLoS One. 8, 8, p. e69299

Research output: Contribution to journalArticle

Open Access
Adult Stem Cells
Amnion
Lung Injury
Stem cells
anti-inflammatory activity
10 Citations (Scopus)

A pilot study of a mobile-phone-based home monitoring system to assist in remote interventions in cases of acute exacerbation of COPD

Ding, H., Karunanithi, M., Kanagasingam, Y., Vignarajan, J. & Moodley, Y., 2014, In : Journal of Telemedicine and Telecare. 20, 3, p. 128-134

Research output: Contribution to journalArticle

A standardised protocol for the evaluation of small extracellular vesicles in plasma by imaging flow cytometry

Armitage, J. D., Tan, D. B. A., Cha, L., Clark, M., Gray, E. S., Fuller, K. A. & Moodley, Y. P., 1 May 2019, In : Journal of Immunological Methods. 468, p. 61-66 6 p.

Research output: Contribution to journalArticle

Flow Cytometry
Lighting
Extracellular Vesicles

A standardized diagnostic ontology for fibrotic interstitial lung disease

Moodley, Y., 15 May 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 10, p. 1365-1366 2 p.

Research output: Contribution to journalLetter

19 Citations (Scopus)

Australian idiopathic pulmonary fibrosis registry: Vital lessons from a national prospective collaborative project

Moodley, Y., Goh, N., Glaspole, I. N., Macansh, S., Haydn Walters, E., Chapman, S. A., Hopkins, P. M. A., Reynolds, P. N., Zappala, C. J., Cooper, W., Mahar, A. M., Ellis, S. J., Mccormack, S., Darbishire, W., Wood-Baker, R. R. & Corte, T. J., 2014, In : Respirology. 19, 7, p. 1088-1091

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Registries
Research
44 Citations (Scopus)

Baseline characteristics of idiopathic pulmonary fibrosis: analysis from the Australian Idiopathic Pulmonary Fibrosis Registry

Jo, H. E., Glaspole, I., Grainge, C., Goh, N., Hopkins, P. M. A., Moodley, Y., Reynolds, P. N., Chapman, S., Walters, E. H., Zappala, C., Allan, H., Keir, G. J., Hayen, A., Cooper, W. A., Mahar, A. M., Ellis, S., Macansh, S. & Corte, T. J., Feb 2017, In : The European Respiratory Journal. 49, 2, 1601592.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Registries
Mortality
Lung Volume Measurements
Cohort Effect
39 Citations (Scopus)

Cellular therapies for lung disease: a distant horizon

Moodley, Y., Manuelpillai, U. & Weiss, DJ., 2011, In : Respirology. 16, 2, p. 223-237

Research output: Contribution to journalArticle

Open Access

CLINICAL FEATURES AND LONG-TERM OUTCOME OF PATIENTS WITH SADDLE PULMONARY EMBOLISM: EXPERIENCE FROM TWO TERTIARY CENTRES

Harryanto, H., Ho, A., Solangaarachchi, M., Kuok, Y., Moodley, Y. & Mulrennan, S., Mar 2019, In : Respirology. 24, p. 144-144 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

74 Citations (Scopus)

Comparison of the morphological and biochemical changes in normal human lung fibroblasts and fibroblasts derived from lungs of patients with idiopathic pulmonary fibrosis during FasL-induced apoptosis

Moodley, Y. P., Caterina, P., Scaffidi, A. K., Misso, N., Papadimitriou, J., Mcanulty, R. J., Laurent, G. J., Thompson, P. & Knight, D. A., 2004, In : Journal of Pathology. 202, 4, p. 486-495

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Fibroblasts
Apoptosis
Lung
Caspase 3

Considerations in the Diagnosis of Idiopathic Pulmonary Fibrosis

Moodley, Y., 1 Mar 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 5, p. 665-666 2 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Determinants and outcomes of prolonged anxiety and depression in idiopathic pulmonary fibrosis

Glaspole, I. N., Watson, A. L., Allan, H., Chapman, S., Cooper, W., Corte, T. J., Ellis, S., Grainge, C., Goh, N., Hopkins, P., Keir, G., Macansh, S., Mahar, A., Moodley, Y., Reynolds, P., Ryerson, C. J., Walters, E. H., Zappala, C. J. & Holland, A. E., 1 Aug 2017, In : European Respiratory Journal. 50, 2, 4 p., 1700168.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Diagnosis and management of idiopathic pulmonary fibrosis: Thoracic society of Australia and New Zealand and lung foundation australia position statements summary

Jo, H. E., Prasad, J. D., Troy, L. K., Mahar, A., Bleasel, J., Ellis, S. J., Chambers, D. C., Holland, A. E., Lake, F. R., Keir, G., Goh, N. S., Wilsher, M., de Boer, S., Moodley, Y., Grainge, C., Whitford, H. M., Chapman, S. A., Reynolds, P. N., Beatson, D., Jones, L. J. & 4 othersHopkins, P., Allan, H. M., Glaspole, I. & Corte, T. J., 5 Feb 2018, In : Medical Journal of Australia. 208, 2, p. 82-88 7 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
New Zealand
Thorax
Lung
Interstitial Lung Diseases
15 Citations (Scopus)

Disease progression in idiopathic pulmonary fibrosis with mild physiological impairment: Analysis from the Australian IPF registry

Jo, H. E., Glaspole, I., Moodley, Y., Chapman, S., Ellis, S., Goh, N., Hopkins, P., Keir, G., Mahar, A., Cooper, W., Reynolds, P., Haydn Walters, E., Zappala, C., Grainge, C., Allan, H., Macansh, S. & Corte, T. J., 25 Jan 2018, In : BMC Pulmonary Medicine. 18, 1, 19.

Research output: Contribution to journalArticle

Open Access
Idiopathic Pulmonary Fibrosis
Registries
Disease Progression
Lung Diseases
Survival
6 Citations (Scopus)

Do all patients with idiopathic pulmonary fibrosis warrant a trial of therapeutic intervention? A pro-con perspective

Moodley, Y., Corte, T. J., Richeldi, L. & King, T. E., 2015, In : Respirology. 20, 3, p. 389-394

Research output: Contribution to journalArticle

Open Access
Idiopathic Pulmonary Fibrosis
Pulmonary Fibrosis
Therapeutics
Safety
Gases
4 Citations (Scopus)

Dysfunctional Immunity and Microbial Adhesion Molecules in Smoking-induced Pneumonia

Eapen, M. S., Sharma, P., Moodley, Y. P., Hansbro, P. M. & Sohal, S. S., 15 Jan 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 2, p. 250-251 3 p.

Research output: Contribution to journalLetter

12 Citations (Scopus)

Elevated levels of circulating exosome in COPD patients are associated with systemic inflammation

Tan, D. B. A., Armitage, J., Teo, T. H., Ong, N. E., Shin, H. & Moodley, Y. P., Nov 2017, In : Respiratory Medicine. 132, p. 261-264

Research output: Contribution to journalArticle

Exosomes
Chronic Obstructive Pulmonary Disease
Inflammation
Tumor Necrosis Factor Receptors
C-Reactive Protein
5 Citations (Scopus)

Epithelial disruption: A new paradigm enabling human airway stem cell transplantation

Farrow, N., Cmielewski, P., Donnelley, M., Rout-Pitt, N., Moodley, Y., Bertoncello, I. & Parsons, D., 13 Jun 2018, In : Stem Cell Research and Therapy. 9, 1, 153.

Research output: Contribution to journalArticle

Open Access
Stem Cell Transplantation
Stem cells
Transplantation
Luciferases
Cystic Fibrosis
16 Citations (Scopus)

Evaluating the interstitial lung disease multidisciplinary meeting: A survey of expert centres

Jo, H. E., Corte, T. J., Moodley, Y., Levin, K., Westall, G., Hopkins, P., Chambers, D. & Glaspole, I., 2016, In : BMC Pulmonary Medicine. 16, 1, 22.

Research output: Contribution to journalArticle

Open Access
Interstitial Lung Diseases
Constitution and Bylaws
North America
Documentation
Internet
90 Citations (Scopus)

Fibroblasts Isolated from Normal Lungs and Those with Idiopathic Pulmonary Fibrosis Differ in Interleukin-6/gp 130-Medicated Cell Signaling and Proliferation

Moodley, Y. P., Scaffidi, A. K., Misso, N., Keerthisingam, C., Mcanulty, R. J., Lauren, G. J., Mutsaers, S. E., Thompson, P. & Knight D.a., N. V., 2003, In : American Journal of Pathology. 163, 1, p. 345-354

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Interleukin-6
Fibroblasts
Cell Proliferation
Lung
31 Citations (Scopus)

Health-related quality of life in idiopathic pulmonary fibrosis: Data from the Australian IPF Registry

Glaspole, I. N., Chapman, S. A., Cooper, W. A., Ellis, S. J., Goh, N. S., Hopkins, P. M., Macansh, S., Mahar, A., Moodley, Y. P., Paul, E., Reynolds, P. N., Walters, E. H., Zappala, C. J. & Corte, T. J., Jul 2017, In : Respirology. 22, 5, p. 950-956

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Registries
Quality of Life
Dyspnea
Linear Models

How do new molecular tools apply to my clinical practice?

Yang, I. A. & Moodley, Y., 1 Nov 2018, In : Respirology. 23, 11, p. 991-992 2 p.

Research output: Contribution to journalEditorial

128 Citations (Scopus)

Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair.

Moodley, Y., Ilancheran, S., Samuel, C., Vaghjiani, V., Atienza, D., Williams, E. D., Jenkin, G., Wallace, E., Trounson, A. & Manuelpillai, U., 2010, In : American Journal of Respiratory and Critical Care Medicine. 182, 5, p. 643-651

Research output: Contribution to journalArticle

167 Citations (Scopus)

Human Fetal Membranes: A Source of Stem Cells for Tissue Regeneration and Repair?

Illancheran, S., Moodley, Y. & Manuelpillai, U., 2009, In : Placenta. 30, 1, p. 2-10

Research output: Contribution to journalReview article

12 Citations (Scopus)

Human mesenchymal stem cells attenuate early damage in a ventilated pig model of acute lung injury

Moodley, Y., Sturm, M., Shaw, K., Shimbori, C., Tan, D., Kolb, M. & Graham, R., 2016, In : Stem Cell Research. 17, 1, p. 25-31

Research output: Contribution to journalArticle

Open Access
Acute Lung Injury
Mesenchymal Stromal Cells
Swine
Oleic Acid
Adult Respiratory Distress Syndrome
214 Citations (Scopus)

Human umbilical cord mesenchymal stem cells reduce fibrosis of bleomycin-induced lung injury

Moodley, Y., Atienza, D., Manuelpillai, U., Samuel, CS., Tchongue, J., Ilancheran, S., Boyd, R. & Trounson, A., 2009, In : American Journal of Pathology. 175, 1, p. 303-313

Research output: Contribution to journalArticle

14 Citations (Scopus)

Idiopathic Pulmonary Fibrosis and the Elderly: Diagnosis and Management Considerations

Jo, H. E., Randhawa, S., Corte, T. J. & Moodley, Y., 2016, In : Drugs and Aging. 33, 5, p. 1-14

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Morbidity
Biopsy
Polypharmacy
Terminal Care
4 Citations (Scopus)

Impaired CTLA-4 responses in COPD are associated with systemic inflammation

Tan, D., Fernández, S., Price, P., French, M., Thompson, P. J. & Moodley, Y., 2014, In : Cellular and Molecular Immunology. 11, 6, p. 606-608

Research output: Contribution to journalArticle

16 Citations (Scopus)

Impaired function of regulatory T-cells in patients with chronic obstructive pulmonary disease (COPD)

Tan, D., Fernández, S., Price, P., French, M., Thompson, P. & Moodley, Y., 2014, In : Immunobiology. 219, 12, p. 975-979

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Chronic Obstructive Pulmonary Disease
T-Lymphocytes
Blood Cells
Body Mass Index

Impaired Th1 responses in patients with acute exacerbations of COPD are improved with PD-1 blockade

Tan, D. B. A., Teo, T. H., Setiawan, A. M., Ong, N. E., Zimmermann, M., Hsu, A. C. Y., Wark, P. A. B. & Moodley, Y. P., 1 Mar 2018, In : Clinical Immunology. 188, p. 64-66 3 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease

Tan, D., Teo, T. H., Setiawan, A. M., Ong, N., Zimmermann, M., Price, P., Kirkham, L. A. S. & Moodley, Y. P., Jun 2017, In : Immunology. 151, 2, p. 219-226

Research output: Contribution to journalArticle

CTLA-4 Antigen
Chronic Obstructive Pulmonary Disease
T-Lymphocytes
Regulatory T-Lymphocytes
Blood Cells

In search for a predictive marker of acute exacerbations of idiopathic pulmonary fibrosis

Moodley, Y., 1 Aug 2019, In : Respirology. 2 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Integrated Multidisciplinary Community Service for Chronic Obstructive Pulmonary Disease Reduces Hospitalisations

Chung, L. P., Lake, F., Hyde, E., Mccamley, C., Phuangmalai, N., Lim, M., Waterer, G., Summers, Q. & Moodley, Y., 2016, In : Internal Medicine Journal. 46, 4, p. 427-434

Research output: Contribution to journalArticle

66 Citations (Scopus)

Introduction to stem cells and regenerative medicine

Kolios, G. & Moodley, Y., 2013, In : Respiration. 2013, 85, p. 3-10

Research output: Contribution to journalArticle

100 Citations (Scopus)

Inverse Effects of Interleukin-6 on Apoptosis of Fibroblasts from Pulmonary Fibrosis and Normal Lungs

Moodley, Y. P., Misso, N., Scaffidi, A. K., Fogel-Petrovic, M., Mcanulty, R. J., Laurent, G. J., Thompson, P. & Knight, D. A., 2003, In : American Journal of Respiratory Cell and Molecular Biology. 29, 4, p. 490-498

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Pulmonary Fibrosis
Fibroblasts
Interleukin-6
Apoptosis
2 Citations (Scopus)

Lung Cell Biology

Upham, J. W., Stick, S. & Moodley, Y., 2008, Pediatric Respiratory Medicine. Taussig, L. M. L. L. I. (ed.). Second ed. Philadephia, PA: Mosby International, p. 35-44

Research output: Chapter in Book/Conference paperChapter

76 Citations (Scopus)

Macrophage recognition and phagocytosis of apoptotic fibroblasts is critically dependent on fibroblast-derived thrombospondin 1 and CD36

Moodley, Y., Rigby, P., Bundell, C., Bunt, S., Hayashi, H., Misso, N., Mcanulty, R., Laurent, G., Scaffidi, A., Thompson, P. & Knight, D., 2003, In : American Journal of Pathology. 162, 3, p. 177-179

Research output: Contribution to journalArticle

Thrombospondin 1
Phagocytosis
Fibroblasts
Macrophages
Phagocytes

Mechanisms of impaired anti-bacterial Th1 responses in patients with chronic obstructive pulmonary disease

Tan, D., Singh, D., Walters, H., Wark, P. & Moodley, Y., 15 Sep 2018, In : European Respiratory Journal. 52, 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

3 Citations (Scopus)

Mesenchymal stromal cell infusion modulates systemic immunological responses in stable COPD patients: A phase i pilot study

Armitage, J., Tan, D. B. A., Troedson, R., Young, P., Lam, K. V., Shaw, K., Sturm, M., Weiss, D. J. & Moodley, Y. P., 1 Mar 2018, In : European Respiratory Journal. 51, 3, 1702369.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Metabolomics in chronic lung diseases

Nambiar, S., Bong How, S., Gummer, J., Trengove, R. & Moodley, Y., Feb 2020, In : Respirology. 25, 2, p. 139-148

Research output: Contribution to journalReview article

Metabolomics
Lung Diseases
Chronic Disease
Chronic Obstructive Pulmonary Disease
Idiopathic Pulmonary Fibrosis
32 Citations (Scopus)

Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis

Royce, S. G., Moodley, Y. & Samuel, C. S., Mar 2014, In : Pharmacology & Therapeutics. 141, 3, p. 250-260 11 p.

Research output: Contribution to journalArticle

Occupational and environmental risk factors for Idiopathic Pulmonary Fibrosis in Australia

Abramson, M. J., Murambadoro, T., Alif, S. M., Benke, G., Dharmage, S., Glaspole, I., Hopkins, P., Hoy, R., Klebe, S., Moodley, Y., Rawson, S., Reynolds, P., Wolfe, R., Walters, E. H. & Corte, T. J., 15 Sep 2018, In : European Respiratory Journal. 52, 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

74 Citations (Scopus)

Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts

Scaffidi, A. K., Mutsaers, S. E., Moodley, Y. P., Mcanulty, R. J., Laurent, G. J., Thompson, P. & Knight Da, N. V., 2002, In : British Journal of Pharmacology. 136, p. 793-801

Research output: Contribution to journalArticle

Oncostatin M
Collagen
Fibroblasts
Apoptosis
Lung
25 Citations (Scopus)

Prevalence and prognosis of unclassifiable interstitial lung disease

Troy, L., Glaspole, I., Goh, N., Zappala, C., Hopkins, P., Wilsher, M., Moodley, Y. & Corte, T., 2014, In : European Respiratory Journal. 43, p. 1529

Research output: Contribution to journalLetter

54 Citations (Scopus)

Prostaglandin E-2 and cysteinyl leukotriene concentrations in sputum: association with asthma severity and eosinophilic inflammation

Aggarwal, S., Moodley, Y., Thompson, P. & Misso, N., 2010, In : Clinical and Experimental Allergy. 40, 1, p. 85-93

Research output: Contribution to journalArticle