Yu Suk Choi

Associate Professor, PhD Melb.

  • The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

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Personal profile

Biography

Research Fellow at the University of Sydney, Cardiology / Kolling Institute - Jul 2013 - Jun 2015
Postdoctoral Scholar at the University of California, San Diego (UCSD) Bioengineering (#2 USA) / Sanford Consortium for Regenerative Medicine - Apr 2010 - Jun 2013
PhD at the University of Melbourne, Surgery / O'Brien Institute - Sep 2006 - Feb 2010

Funding overview

18. Department of Health WA - Medical and Health Research Infrastructure Fund Round 23 – CI: Choi YS, 2020, AU$23,412)

17. Sir Charles Gairdner Hospital and Osborne Park Health Care Group Research Advisory Committee’s 2019/20 Research Grant - Application of an ex-vivo hydrogel model to assess and reverse airway smooth muscle cell stiffness in COPD – (CIA: James AL, CIB: Wang K, CIC: Choi YS, CID: Cairncross A, 2020, $30,000)

16. UWA Research Income Growth Grant - Extending UWA/Yonsei University collaboration into new Category 2 and 3 funding to develop spatiotemprally dynamic 4D microenvironments for cancer mechanobiology – (CI: YS Choi, 2019, AU$8,140)

15. Universities Australia DAAD German Research Cooperation – Biaxial substrates combining linear stiffness gradients with nanoscale spacing gradients for mechanobiology – (CI: Choi YS, 2019-2020, AU$20,920)

14. NHMRC CDF1 – stem cell mechanobiology for cardiac regeneration – (CI: Choi YS, 2018-2021 AU$431,000) – relinquished to accept Heart Foundation Future Leader Fellowship

13. Marsden Fund (Royal Society NZ) - Stiffness matters: Unravelling the reciprocal relationship between tissue mechanical stiffness and cellular mechanosensitivity – (CIA: McGlashan S, CIB: Choi YS, 2018-2020 NZ$920,000)

12. Department of Health, Western Australia, Merit Award – Projects – Force of Nature: 3D cell-matrix force-microscopy for stem cell mechanobiology – (CI: Choi YS, 2017-2018 AU$37,500)

11. Department of Health, Western Australia, Merit Award – Fellowship – Stem cell mechanobiology for cardiac regeneration – (CI: Choi YS, 2017-2018 AU$25,000)

 

10. Heart Foundation Future Leader Fellowship – Stem cell mechanobiology for heart regeneration – (CI: Choi YS, 2017-2021 AU$520,000)


9. UWA Research Collaboration Awards 2017 – Developing a 3D Mimic of the Brain – (UWA: Swaminatha-Iyer K, Fitzgerals M, Choi YS, Smith N; UNSW: Evans C, Thordarson P, Martin A; University of Cape Town: Franz T, Davies N / 2017 AU$ 28,000)

8. UHU collaborative Research Network Seed Funding Award – TIPS for generating layered and porous silk membranes suitable for eardrum repair (CIs: Dilley RJ, Day R, Choi YS / Nov 2015 AU$20,000)

7. NHMRC Equipment Grant (UWA) – Philips Premium Portable CX50 Ultrasound System (CIs: Noble P, Pillow J, Gill A, Laing N, Nowak K, McLaughlin R, Kennedy B, Hodgetts S, Pinniger G, Choi YS, Wang K / 2016 AU$ 47,500)

6. NHMRC Project Grant 1098449 - Using mechanotransduction to regulate stem cell fate in heart tissue - YS Choi, AJ Engler, and XL Guan (2016-2018)

5. Atomic Force Microscope – Mill House Foundation for Equipment Grant 2014 (CI: Dr. Choi YS / May 2014 AU$ 132,000)

4. Cardiac differentiation of stem cells by mechanotransduction – Sydney Medical School Early Career Researcher Grant 2014 (CI: Dr. Choi YS / Feb 2014 AU$ 24,766.9)

3. Live cell imaging system - Norma Louise Cordell Blue Equipment Grant (Australia) (CI: Dr. Choi YS / Feb 2014 AU$93,357)

2. ECM stiffness driven cardiac induction of stem cells – Heart Research Australia (Australia) 2014-07 (CI: Dr. Choi YS / Jan 2014 – Dec 2016 AU$147,706.80)

1. Mechanically programmed adipose-derived stem cells to treat muscular dystrophy – Muscular Dystrophy Association (USA) 241665. (PI: Prof. Engler AJ, Co-investigator: Dr. Choi YS / Oct 2012 – Jul 2015 US$390,000)

Current projects

1. Developing stiffness gradient hydrogel to study stem cell fate controlling
2. Stretch bioreactor for lung regeneration using adipose stem cells
3. Stem cell mechanotransduction in osteochondral tissue engineering
4. Using Mechanotransduction to Regulate Stem Cell Fate in Heart Tissue

Teaching overview

UWA

Unit Coordinator
ANHB3323 Cells, Tissues, and Development

Lecturer
SCIE1106 Molecular Biology of the Cell
PHYL3001 Physiology of Membranes, Muscles and Signalling
ENSC3023 Biomedical Engineering

Research

Stem cell mechanotransduction - differentiation, migration, and proliferation for stem cell therapy, tissue engineering, and regenerative medicine

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Stem Cell and Tissue Engineering, PhD, Engineering Cardiac Tissue from Human Adult Stem Cells, University of Melbourne

Award Date: 28 Aug 2010

Industry keywords

  • Bioengineering
  • Biotechnology
  • Health

Research expertise keywords

  • Stem cell biology
  • Regenerative medicine
  • Biomaterials
  • Mechanobiology
  • Cancer biology
  • Metastasis

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