• The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1552 Citations
  • 17 h-Index
20052021
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Personal profile

Biography

Research Fellow at the University of Sydney, Cardiology / Kolling Institute - Jul 2013 - Jun 2015
Postdoctoral Scholar at the University of California, San Diego (UCSD) Bioengineering (#2 USA) / Sanford Consortium for Regenerative Medicine - Apr 2010 - Jun 2013
PhD at the University of Melbourne, Surgery / O'Brien Institute - Sep 2006 - Feb 2010

Funding overview

14. NHMRC CDF1 – stem cell mechanobiology for cardiac regeneration – (CI: Choi YS, 2018-2021 AU$431,000) – relinquished to accept Heart Foundation Future Leader Fellowship

13. Marsden Fund (Royal Society NZ) - Stiffness matters: Unravelling the reciprocal relationship between tissue mechanical stiffness and cellular mechanosensitivity – (CIA: McGlashan S, CIB: Choi YS, 2018-2020 NZ$920,000)

12. Department of Health, Western Australia, Merit Award – Projects – Force of Nature: 3D cell-matrix force-microscopy for stem cell mechanobiology – (CI: Choi YS, 2017-2018 AU$37,500)

11. Department of Health, Western Australia, Merit Award – Fellowship – Stem cell mechanobiology for cardiac regeneration – (CI: Choi YS, 2017-2018 AU$25,000)

 

10. Heart Foundation Future Leader Fellowship – Stem cell mechanobiology for heart regeneration – (CI: Choi YS, 2017-2021 AU$520,000)


9. UWA Research Collaboration Awards 2017 – Developing a 3D Mimic of the Brain – (UWA: Swaminatha-Iyer K, Fitzgerals M, Choi YS, Smith N; UNSW: Evans C, Thordarson P, Martin A; University of Cape Town: Franz T, Davies N / 2017 AU$ 28,000)

8. UHU collaborative Research Network Seed Funding Award – TIPS for generating layered and porous silk membranes suitable for eardrum repair (CIs: Dilley RJ, Day R, Choi YS / Nov 2015 AU$20,000)

7. NHMRC Equipment Grant (UWA) – Philips Premium Portable CX50 Ultrasound System (CIs: Noble P, Pillow J, Gill A, Laing N, Nowak K, McLaughlin R, Kennedy B, Hodgetts S, Pinniger G, Choi YS, Wang K / 2016 AU$ 47,500)

6. NHMRC Project Grant 1098449 - Using mechanotransduction to regulate stem cell fate in heart tissue - YS Choi, AJ Engler, and XL Guan (2016-2018)

5. Atomic Force Microscope – Mill House Foundation for Equipment Grant 2014 (CI: Dr. Choi YS / May 2014 AU$ 132,000)

4. Cardiac differentiation of stem cells by mechanotransduction – Sydney Medical School Early Career Researcher Grant 2014 (CI: Dr. Choi YS / Feb 2014 AU$ 24,766.9)

3. Live cell imaging system - Norma Louise Cordell Blue Equipment Grant (Australia) (CI: Dr. Choi YS / Feb 2014 AU$93,357)

2. ECM stiffness driven cardiac induction of stem cells – Heart Research Australia (Australia) 2014-07 (CI: Dr. Choi YS / Jan 2014 – Dec 2016 AU$147,706.80)

1. Mechanically programmed adipose-derived stem cells to treat muscular dystrophy – Muscular Dystrophy Association (USA) 241665. (PI: Prof. Engler AJ, Co-investigator: Dr. Choi YS / Oct 2012 – Jul 2015 US$390,000)

Current projects

1. Developing stiffness gradient hydrogel to study stem cell fate controlling
2. Stretch bioreactor for lung regeneration using adipose stem cells
3. Stem cell mechanotransduction in osteochondral tissue engineering
4. Using Mechanotransduction to Regulate Stem Cell Fate in Heart Tissue

Teaching overview

UWA

Unit Coordinator
ANHB3323 Cells, Tissues, and Development
ANHB3320 Human Biology: Applications and Investigations

Lecturer
SCIE1106 Molecular Biology of the Cell
ANHB2217 Human Neurobiology
PHYL2002 Physiology of the Cell
PHYL3001 Physiology of Membranes, Muscles and Signalling
PHYL3004 Physiology of Integrated Organ Function

Guest lecture / USyd Biomed Eng - Tissue Engineering
Guest lecture / USyd Biomed Eng - Biomechanics
Lecture / UCSD - BENG087 freshman seminar
Lab module / UCSD - BENG277 tissue eng lab module

Research

Stem cell mechanotransduction - differentiation, migration, and proliferation for stem cell therapy, tissue engineering, and regenerative medicine

Keywords

  • Bioengineering
  • Biotechnology
  • Health
  • Stem cell biology
  • Regenerative medicine
  • Biomaterials
  • Mechanobiology
  • Tissue Engineering

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2018

  • 1552 Citations
  • 17 h-Index
  • 25 Article
  • 5 Chapter
  • 2 Review article
  • 1 Conference paper
Stem cells
Extracellular Matrix
Stem Cells
Stiffness
Throughput
4 Citations (Scopus)

Engineering spheroids potentiating cell-cell and cell-ECM interactions by self-assembly of stem cell microlayer

Lee, Y. B., Kim, E. M., Byun, H., Chang, H. K., Jeong, K., Aman, Z. M., Choi, Y. S., Park, J. & Shin, H., 1 May 2018, In : Biomaterials. 165, p. 105-120 16 p.

Research output: Contribution to journalArticle

Military electronic countermeasures
Stem cells
Cell Communication
Self assembly
Stem Cells

Graphene-functionalized biomimetic scaffolds for tissue regeneration

Shin, Y. C., Song, S. J., Hong, S. W., Oh, J. W., Hwang, Y. S., Choi, Y. S. & Han, D. W., 24 Nov 2018, Biomimetic medical materials: From nanotechnology to 3D bioprinting. Noh, I. (ed.). Singapore: Springer, p. 73-89 17 p. (Advances in Experimental Medicine and Biology; vol. 1064).

Research output: Chapter in Book/Conference paperChapter

Tissue Scaffolds
Tissue regeneration
Biomimetics
Graphite
Regeneration

Hydrogels with an embossed surface: An all-in-one platform for mass production and culture of human adipose-derived stem cell spheroids

Kim, S-J., Park, J., Byun, H., Park, Y-W., Major, L. G., Lee, D. Y., Choi, Y. S. & Shin, H., 22 Oct 2018, In : Biomaterials. 188, p. 198-212 15 p.

Research output: Contribution to journalArticle

Hydrogels
Stem cells
Cell culture
Stem Cells
Hydrogel
1 Citation (Scopus)

A generalized labeled multi-Bernoulli tracker for time lapse cell migration

Kim, D. Y., Vo, B-N., Thian, A. & Choi, Y. S., 31 Oct 2017, A generalized labeled multi-Bernoulli tracker for time lapse cell migration. New York: IEEE, Institute of Electrical and Electronics Engineers, p. 20-25

Research output: Chapter in Book/Conference paperConference paper

Set theory
Microscopic examination
Uncertainty
Experiments

Projects 2015 2021

Prizes

Barbara Ell Seminar Series Lecturer

Yu Suk Choi (Recipient), 2017

Prize: Other distinction

Global Center of Excellence Program Lecturer

Yu Suk Choi (Recipient), 2012

Prize: Other distinction

Press / Media