Research output per year
Research output per year
Personal profile
Biography
Research Fellow at the University of Sydney, Cardiology / Kolling Institute - Jul 2013 - Jun 2015
Postdoctoral Scholar at the University of California, San Diego (UCSD) Bioengineering (#2 USA) / Sanford Consortium for Regenerative Medicine - Apr 2010 - Jun 2013
PhD at the University of Melbourne, Surgery / O'Brien Institute - Sep 2006 - Feb 2010
Postdoctoral Scholar at the University of California, San Diego (UCSD) Bioengineering (#2 USA) / Sanford Consortium for Regenerative Medicine - Apr 2010 - Jun 2013
PhD at the University of Melbourne, Surgery / O'Brien Institute - Sep 2006 - Feb 2010
Current projects
1. Cancer mechanobiology: the role of tumor microenvironment on metastasis
2. 3D stem cell mechanotransduction
3. Tissue-specific cell mechanosensation
4. Developing smart biomaterials to study cell mechanobiology
Teaching overview
Unit Coordinator
ANHB3323 Cells, Tissues, and Development
ANHB3320 Human Biology: Applications and Investigations II
Lecturer
SCIE1106 Molecular Biology of the Cell
PHYL3001 Physiology of Membranes, Muscles and Signalling
ENSC3023 Biomedical Engineering
Research
Stem cell mechanotransduction - differentiation, migration, and proliferation for stem cell therapy, tissue engineering, and regenerative medicine
Cancer mechanobiology - mechanical challenges throughout metastatic journey
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Stem Cell and Tissue Engineering, PhD, Engineering Cardiac Tissue from Human Adult Stem Cells, University of Melbourne
Award Date: 28 Aug 2010
Industry keywords
- Bioengineering
- Biotechnology
- Health
Research expertise keywords
- Stem cell biology
- Regenerative medicine
- Biomaterials
- Mechanobiology
- Cancer biology
- Metastasis
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Volume adaptation controls stem cell mechanotransduction
Major, L., Holle, A. W., Young, J. L., Hepburn, M., Jeong, K., Chin, I., Sanderson, R., Jeong, J. H., Aman, Z., Kennedy, B., Hwang, Y., Han, D.-W., Park, H. W., Guan, K.-L., Spatz, J. P. & Choi, Y. S., 11 Dec 2019, In: ACS Applied Materials and Interfaces. 11, 49, p. 45520-45530 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile73 Citations (Scopus)146 Downloads (Pure) -
Stem Cell Mechanosensation on Gelatin Methacryloyl (GelMA) Stiffness Gradient Hydrogels
Kim, C., Young, J. L., Holle, A. W., Jeong, K., Major, L. G., Jeong, J. H., Aman, Z. M., Han, D. W., Hwang, Y., Spatz, J. P. & Choi, Y. S., 1 Feb 2020, In: Annals of Biomedical Engineering. 48, 2, p. 893-902 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile94 Citations (Scopus)530 Downloads (Pure) -
Three-dimensional imaging of cell and extracellular matrix elasticity using quantitative micro-elastography
Hepburn, M., Wijesinghe, P., Major, L., Li, J., Mowla, A., Astell, C., Park, H. W., Hwang, Y., Choi, Y. S. & Kennedy, B., 1 Feb 2020, In: Biomedical Optics Express. 11, 2, p. 867-884 18 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Citations (Scopus) -
Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels
Hadden, W. J., Young, J. L., Holle, A. W., McFetridge, M. L., Kim, D. Y., Wijesinghe, P., Taylor-Weiner, H., Wen, J. H., Lee, A. R., Bieback, K., Vo, B.-N., Sampson, D. D., Kennedy, B. F., Spatz, J. P., Engler, A. J. & Choi, Y. S., 30 May 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 22, p. 5647-5652 6 p.Research output: Contribution to journal › Article › peer-review
Open Access395 Citations (Scopus) -
A Visible Light-Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing
Ansari, A., Bhowmik, S., Zhang, K., Reeves, C. L., Vahala, D., Choi, Y. S., Gelmi, A., Combes, A. N., Tuan, R. S., Truong, V. X., Forsythe, J. S. & Frith, J. E., 1 Apr 2025, (E-pub ahead of print) In: Advanced Functional Materials. 16 p., 2501585.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Additional file 1 of Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination
Huh, H. D. (Creator), Sub, Y. (Creator), Oh, J. (Creator), Kim, Y. E. (Creator), Lee, J. Y. (Creator), Kim, H.-R. (Creator), Lee, S. (Creator), Lee, H. (Creator), Pak, S. (Creator), Amos, S. E. (Creator), Vahala, D. (Creator), Park, J. H. (Creator), Shin, J. E. (Creator), Park, S. Y. (Creator), Kim, H. S. (Creator), Roh, Y. H. (Creator), Lee, H.-W. (Creator), Guan, K.-L. (Creator), Choi, Y. S. (Creator), Jeong, J. (Creator), Choi, J. (Creator), Roe, J.-S. (Creator), Gee, H. Y. (Creator) & Park, H. W. (Creator), Figshare, 14 Apr 2023
DOI: 10.6084/m9.figshare.22626011, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Reprogramming_anchorage_dependency_by_adherent-to-suspension_transition_promotes_metastatic_dissemination/22626011 and one more link, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Reprogramming_anchorage_dependency_by_adherent-to-suspension_transition_promotes_metastatic_dissemination/22626011/1 (show fewer)
Dataset
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Broadening assay capabilities with CLARIOstar Plus multimode platereader
Ben-Ary, G. (CoPI), Chen, K. (CoPI), Choi, Y. S. (CoPI), Fox, A. (CoPI), Hodgetts, S. (CoPI), Mark, P. (CoPI), Pillow, J. (CoPI), Pool, K. (CoPI), Rodger, J. (CoPI), Smith, J. (CoPI) & Wyrwoll, C. (CoPI)
The University of Western Australia
6/01/25 → 8/01/35
Project: Research
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Nuclear mechanobiology in migration and metastasis
Fox, A. (Investigator 01) & Choi, Y. S. (Investigator 02)
NHMRC National Health and Medical Research Council
1/01/23 → 31/12/25
Project: Research
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Dynamic Mechano-Microscopy for use in Mechanobiology
Kennedy, B. (Investigator 01) & Choi, Y. S. (Investigator 02)
ARC Australian Research Council
10/05/22 → 31/12/25
Project: Research
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Core infrastructure: high-throughput nanodrop spectrophotometer
Kretzmann, J. (Investigator 01), Evans, C. (Investigator 02), Choi, Y. S. (Investigator 03), Waryah, C. (Investigator 04), Sarkar-Tyson, M. (Investigator 05), Wang, T. (Investigator 06), Bond, C. (Investigator 07), Vrielink, A. (Investigator 08), Smith, N. (Investigator 09), Lesterhuis, W. (Investigator 10), Marshall, A. (Investigator 11), Stubbs, K. (Investigator 12), Breese, K. (Investigator 13), Chen, K. (Investigator 14), Smithers, L. (Investigator 15), Wylie, B. (Investigator 16), Wang, E. (Investigator 17) & Blancafort, P. (Investigator 18)
NHMRC National Health and Medical Research Council
15/03/24 → 31/12/24
Project: Research
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Zeiss Celldiscoverer7 for automated high resolution imaging of complex biomedical samples
Fox, A. (Investigator 01), Choi, Y. S. (Investigator 02), Rodger, J. (Investigator 03), Tang, A. (Investigator 04), Hool, L. (Investigator 05), Pillow, J. (Investigator 06), Lister, R. (Investigator 07), Bond, C. (Investigator 08), Hodgetts, S. (Investigator 09), Chen, K. (Investigator 10), Blancafort, P. (Investigator 11), Redfern, A. (Investigator 12), Swaminatha Iyer, I. (Investigator 13), Smith, N. (Investigator 14), Marshall, A. (Investigator 15), Fear, M. (Investigator 16), Wood, F. (Investigator 17), Evans, C. (Investigator 18), Chooi, H. (Investigator 19) & Rassell, A. (Investigator 20)
NHMRC National Health and Medical Research Council
1/07/22 → 31/10/23
Project: Research
Prizes
Press/Media
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Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels
17/05/17
1 item of Media coverage
Press/Media: Press / Media