• The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth


  • 1775 Citations
  • 19 h-Index
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Personal profile


Research Fellow at the University of Sydney, Cardiology / Kolling Institute - Jul 2013 - Jun 2015
Postdoctoral Scholar at the University of California, San Diego (UCSD) Bioengineering (#2 USA) / Sanford Consortium for Regenerative Medicine - Apr 2010 - Jun 2013
PhD at the University of Melbourne, Surgery / O'Brien Institute - Sep 2006 - Feb 2010

Funding overview

14. NHMRC CDF1 – stem cell mechanobiology for cardiac regeneration – (CI: Choi YS, 2018-2021 AU$431,000) – relinquished to accept Heart Foundation Future Leader Fellowship

13. Marsden Fund (Royal Society NZ) - Stiffness matters: Unravelling the reciprocal relationship between tissue mechanical stiffness and cellular mechanosensitivity – (CIA: McGlashan S, CIB: Choi YS, 2018-2020 NZ$920,000)

12. Department of Health, Western Australia, Merit Award – Projects – Force of Nature: 3D cell-matrix force-microscopy for stem cell mechanobiology – (CI: Choi YS, 2017-2018 AU$37,500)

11. Department of Health, Western Australia, Merit Award – Fellowship – Stem cell mechanobiology for cardiac regeneration – (CI: Choi YS, 2017-2018 AU$25,000)


10. Heart Foundation Future Leader Fellowship – Stem cell mechanobiology for heart regeneration – (CI: Choi YS, 2017-2021 AU$520,000)

9. UWA Research Collaboration Awards 2017 – Developing a 3D Mimic of the Brain – (UWA: Swaminatha-Iyer K, Fitzgerals M, Choi YS, Smith N; UNSW: Evans C, Thordarson P, Martin A; University of Cape Town: Franz T, Davies N / 2017 AU$ 28,000)

8. UHU collaborative Research Network Seed Funding Award – TIPS for generating layered and porous silk membranes suitable for eardrum repair (CIs: Dilley RJ, Day R, Choi YS / Nov 2015 AU$20,000)

7. NHMRC Equipment Grant (UWA) – Philips Premium Portable CX50 Ultrasound System (CIs: Noble P, Pillow J, Gill A, Laing N, Nowak K, McLaughlin R, Kennedy B, Hodgetts S, Pinniger G, Choi YS, Wang K / 2016 AU$ 47,500)

6. NHMRC Project Grant 1098449 - Using mechanotransduction to regulate stem cell fate in heart tissue - YS Choi, AJ Engler, and XL Guan (2016-2018)

5. Atomic Force Microscope – Mill House Foundation for Equipment Grant 2014 (CI: Dr. Choi YS / May 2014 AU$ 132,000)

4. Cardiac differentiation of stem cells by mechanotransduction – Sydney Medical School Early Career Researcher Grant 2014 (CI: Dr. Choi YS / Feb 2014 AU$ 24,766.9)

3. Live cell imaging system - Norma Louise Cordell Blue Equipment Grant (Australia) (CI: Dr. Choi YS / Feb 2014 AU$93,357)

2. ECM stiffness driven cardiac induction of stem cells – Heart Research Australia (Australia) 2014-07 (CI: Dr. Choi YS / Jan 2014 – Dec 2016 AU$147,706.80)

1. Mechanically programmed adipose-derived stem cells to treat muscular dystrophy – Muscular Dystrophy Association (USA) 241665. (PI: Prof. Engler AJ, Co-investigator: Dr. Choi YS / Oct 2012 – Jul 2015 US$390,000)

Current projects

1. Developing stiffness gradient hydrogel to study stem cell fate controlling
2. Stretch bioreactor for lung regeneration using adipose stem cells
3. Stem cell mechanotransduction in osteochondral tissue engineering
4. Using Mechanotransduction to Regulate Stem Cell Fate in Heart Tissue

Teaching overview


Unit Coordinator
ANHB3323 Cells, Tissues, and Development
ANHB3320 Human Biology: Applications and Investigations

SCIE1106 Molecular Biology of the Cell
ANHB2217 Human Neurobiology
PHYL2002 Physiology of the Cell
PHYL3001 Physiology of Membranes, Muscles and Signalling
PHYL3004 Physiology of Integrated Organ Function

Guest lecture / USyd Biomed Eng - Tissue Engineering
Guest lecture / USyd Biomed Eng - Biomechanics
Lecture / UCSD - BENG087 freshman seminar
Lab module / UCSD - BENG277 tissue eng lab module


Stem cell mechanotransduction - differentiation, migration, and proliferation for stem cell therapy, tissue engineering, and regenerative medicine


  • Bioengineering
  • Biotechnology
  • Health
  • Stem cell biology
  • Regenerative medicine
  • Biomaterials
  • Mechanobiology
  • Tissue Engineering

Fingerprint Dive into the research topics where Yu Suk Choi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Stem cells Chemical Compounds
Stem Cells Medicine & Life Sciences
Tissue engineering Chemical Compounds
Tissue Engineering Medicine & Life Sciences
Mesenchymal Stromal Cells Medicine & Life Sciences
Hydrogels Medicine & Life Sciences
Tissue Chemical Compounds
Adipose Tissue Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2020

  • 1775 Citations
  • 19 h-Index
  • 28 Article
  • 5 Chapter
  • 3 Review article
  • 1 Conference paper

Stem Cell Mechanosensation on Gelatin Methacryloyl (GelMA) Stiffness Gradient Hydrogels

Kim, C., Young, J. L., Holle, A. W., Jeong, K., Major, L. G., Jeong, J. H., Aman, Z. M., Han, D. W., Hwang, Y., Spatz, J. P. & Choi, Y. S., 1 Feb 2020, In : Annals of Biomedical Engineering. 48, 2, p. 893-902

Research output: Contribution to journalArticle

Stem cells
Oils and fats

A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology

Chin, I. L., Hool, L. & Choi, Y. S., 5 Jun 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 10 p., 133.

Research output: Contribution to journalReview article

Open Access
7 Citations (Scopus)

Hydrogels with an embossed surface: An all-in-one platform for mass production and culture of human adipose-derived stem cell spheroids

Kim, S-J., Park, J., Byun, H., Park, Y-W., Major, L. G., Lee, D. Y., Choi, Y. S. & Shin, H., Jan 2019, In : Biomaterials. 188, p. 198-212 15 p.

Research output: Contribution to journalArticle

Stem cells
Cell culture
Stem Cells

Lotus seedpod-inspired hydrogels as an all-in-one platform for culture and delivery of stem cell spheroids

Kim, S-J., Park, J., Kim, E. M., Choi, J. J., Kim, H. N., Chin, I. L., Choi, Y. S., Moon, S. H. & Shin, H., 1 Dec 2019, In : Biomaterials. 225, 119534.

Research output: Contribution to journalArticle

Stem cells
Cell culture
Stem Cells
1 Citation (Scopus)

Volume adaptation controls stem cell mechanotransduction

Major, L., Holle, A. W., Young, J. L., Hepburn, M., Jeong, K., Chin, I., Sanderson, R., Jeong, J. H., Aman, Z., Kennedy, B., Hwang, Y., Han, D-W., Park, H. W., Guan, K-L., Spatz, J. P. & Choi, Y. S., 11 Dec 2019, In : ACS Applied Materials and Interfaces. 11, 49, p. 45520-45530 11 p.

Research output: Contribution to journalArticle

Open Access
Stem cells
Peroxisome Proliferator-Activated Receptors

Projects 2015 2021


Barbara Ell Seminar Series Lecturer

Yu Suk Choi (Recipient), 2017

Prize: Other distinction

Global Center of Excellence Program Lecturer

Yu Suk Choi (Recipient), 2012

Prize: Other distinction

Press / Media