• The University of Western Australia (M561), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1866 Citations
  • 21 h-Index
1989 …2021
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Fingerprint Dive into the research topics where Ursula Kees is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 17 Similar Profiles
Precursor Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Genes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Neuroblastoma Medicine & Life Sciences

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Research Output 1989 2019

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 othersFailes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 16 May 2019, In : Oncogene. 38, 20, p. 3824-3842 19 p.

Research output: Contribution to journalArticle

Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic leukemia

Cheung, L. C., Cruickshank, M. N., Hughes, A. M., Singh, S., Chua, G-A., Ford, J., Ferrari, E., Oommen, J., Malinge, S., Lock, R. B., Kees, U. R. & Kotecha, R. S., 30 Jun 2019, In : Haematologica. 104, 7, 4 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment

Cheung, L. C., Tickner, J., Hughes, A. M., Skut, P., Howlett, M., Foley, B., Oommen, J., Wells, J. E., He, B., Singh, S., Chua, G. A., Ford, J., Mullighan, C. G., Kotecha, R. S. & Kees, U. R., 1 Nov 2018, In : Leukemia. 32, 11, p. 2326-2338 13 p.

Research output: Contribution to journalArticle

Open Access
Leukemia
Bone Marrow
Precursor Cell Lymphoblastic Leukemia-Lymphoma
zoledronic acid
Bone and Bones
1 Citation (Scopus)

Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease

Stirnweiss, A., Oommen, J., Kotecha, R. S., Kees, U. R. & Beesley, A. H., 22 Dec 2017, In : Oncotarget. 8, 68, p. 112313-112329 17 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin

Cruickshank, M. N., Ford, J., Cheung, L. C., Heng, J., Singh, S., Wells, J., Failes, T. W., Arndt, G. M., Smithers, N., Prinjha, R. K., Anderson, D., Carter, K. W., Gout, A. M., Lassmann, T., O'Reilly, J., Cole, C. H., Kotecha, R. S. & Kees, U. R., 1 Jan 2017, In : Leukemia. 31, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

Open Access
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Histone Deacetylase Inhibitors
Cell Line
Pharmaceutical Preparations

Projects 2004 2021