Thomas Ledowski

Professor, M.D., P.D., DEAA, FANZCA

  • The University of Western Australia (M572), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1521 Citations
  • 21 h-Index
19972019
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Research Output 1997 2019

2019

Cheaper drugs and techniques to fulfill chief executive officer perspectives - any choices?

Thomas, B. E. & Ledowski, T., 1 Apr 2019, In : Current Opinion in Anaesthesiology. 32, 2, p. 195-199 5 p.

Research output: Contribution to journalArticle

Budgets
Administrative Personnel
Health Care Sector
Patents
Quality of Health Care
2 Citations (Scopus)

Objective monitoring of nociception: a review of current commercial solutions

Ledowski, T., 30 Apr 2019, (Accepted/In press) In : British Journal of Anaesthesia.

Research output: Contribution to journalReview article

Nociception
Equipment and Supplies
Anesthesia and Analgesia
Vital Signs
Acute Pain
Acute Pain
Postoperative Pain
Arousal
Observational Studies
Prospective Studies
1 Citation (Scopus)

Surgical pleth index: prospective validation of the score to predict moderate-to-severe postoperative pain

Ledowski, T., Schneider, M., Gruenewald, M., Goyal, R. K., Teo, S. R. & Hruby, J., 12 Mar 2019, In : British Journal of Anaesthesia. 5 p.

Research output: Contribution to journalArticle

Postoperative Pain
Arterial Pressure
Heart Rate
Sensitivity and Specificity
Pain
2018
9 Citations (Scopus)

Cuffed vs. uncuffed tracheal tubes in children: a randomised controlled trial comparing leak, tidal volume and complications

Chambers, N. A., Ramgolam, A., Sommerfield, D., Zhang, G., Ledowski, T., Thurm, M., Lethbridge, M., Hegarty, M. K. & von Ungern-Sternberg, B. S., 1 Feb 2018, In : Anaesthesia. 73, 2, p. 160-168 9 p.

Research output: Contribution to journalArticle

Tidal Volume
Ventilation
Randomized Controlled Trials
Pressure
Mechanical Ventilators
1 Citation (Scopus)

Effects of muscle relaxants on ischaemia damage in skeletal muscle

Ledowski, T., Nißler, S., Wenk, M., Pogatzki-Zahn, E. M. & Segelcke, D., 11 Apr 2018, In : Scientific Reports. 8, 1, 7 p.

Research output: Contribution to journalArticle

Open Access
Skeletal Muscle
Ischemia
Muscles
Dystrophin
Muscle Cells

Mivacurium: a Review

Molloy, L. S. & Ledowski, T., 21 Mar 2018, In : Current Anesthesiology Reports. 8, 2, p. 125-129 5 p.

Research output: Contribution to journalReview article

2017
3 Citations (Scopus)

Monitoring nociception - Getting 'there yet' might be easier with a road map

Ledowski, T., 1 Oct 2017, In : British Journal of Anaesthesia. 119, 4, p. 716-717 2 p.

Research output: Contribution to journalEditorial

7 Citations (Scopus)

Surgical pleth index: Prediction of postoperative pain in children?

Ledowski, T., Sommerfield, D., Slevin, L., Conrad, J. & Von Ungern-Sternberg, B. S., 1 Nov 2017, In : British Journal of Anaesthesia. 119, 5, p. 979-983 5 p.

Research output: Contribution to journalArticle

Postoperative Pain
Postoperative Care
Acute Pain
Anesthesia
Sensitivity and Specificity
Open Access
Reconstructive Surgical Procedures
Muscle Relaxation
Superficial Back Muscles
Observational Studies
Dissection
2016
7 Citations (Scopus)

Current Trends in Neuromuscular Blockade, Management, and Monitoring amongst Singaporean Anaesthetists

Teoh, W. H., Ledowski, T. & Tseng, P. S., 2016, In : Anesthesiology Research and Practice. 2016, 7284146.

Research output: Contribution to journalArticle

Open Access
Neuromuscular Monitoring
Practice Guidelines
Singapore
Patient Safety
Costs and Cost Analysis
2 Citations (Scopus)

Laparoscopic Surgery and Muscle Relaxants: Is Deep Block Really Not Helpful?

Ledowski, T., 2016, In : Anesthesia and Analgesia. 122, 1, p. 290-293 4 p.

Research output: Contribution to journalLetter

17 Citations (Scopus)

Surgical pleth index: Prediction of postoperative pain and influence of arousal

Ledowski, T., Burke, J. & Hruby, J., 2016, In : British Journal of Anaesthesia. 117, 3, p. 371-374 4 p.

Research output: Contribution to journalArticle

Postoperative Pain
Arousal
Anesthesia
Entropy
Pain
2 Citations (Scopus)
2015
4 Citations (Scopus)

A comparison of the i-gel™ and the PRO-Breathe® laryngeal mask during pressure support ventilation in children

Drake-Brockman, T., Ledowski, T., Hegarty, M., Gessner, M. & von Ungern-Sternberg, B. S., 2015, In : Anaesthesia. 70, 12, p. 1412-1417

Research output: Contribution to journalArticle

Laryngeal Masks
Ventilation
Gels
Pressure
Positive-Pressure Respiration
21 Citations (Scopus)

Deep neuromuscular block reduces intra-abdominal pressure requirements during laparoscopic cholecystectomy: A prospective observational study

Van Wijk, R. M. A. W., Watts, R. W., Ledowski, T., Trochsler, M. I., Moran, J. L. & Arenas, G. W. N., 2015, In : ACTA Anaesthesiologica Scandinavica. 59, 4, p. 434-440

Research output: Contribution to journalArticle

Neuromuscular Blockade
Laparoscopic Cholecystectomy
Observational Studies
Prospective Studies
Pressure
3 Citations (Scopus)

Effect of muscle relaxation on the oxygenation of human skeletal muscle: A prospective in-vivo experiment using an isolated forearm technique

Rhee, K. Y., Kim, T-Y., Oh, I., Lee, S-J. & Ledowski, T., 2015, In : Korean Journal of Anesthesiology. 68, 1, p. 13-16

Research output: Contribution to journalArticle

Open Access
Tourniquets
Muscle Relaxation
Forearm
Skeletal Muscle
Near-Infrared Spectroscopy
9 Citations (Scopus)
Muscle Relaxation
Laparoscopy
Neuromuscular Blocking Agents
Neuromuscular Blockade
Insufflation
7 Citations (Scopus)
Open Access
Neuromuscular Monitoring
Tertiary Care Centers
Teaching Hospitals
Muscles
Neuromuscular Blocking Agents
12 Citations (Scopus)

Postoperative residual neuromuscular paralysis at an Australian tertiary children's hospital

Ledowski, T., O'Dea, B., Meyerkort, L., Hegarty, M. & von Ungern-Sternberg, B. S., 2015, In : Anesthesiology Research and Practice. 2015, p. 1-4

Research output: Contribution to journalArticle

Open Access
Delayed Emergence from Anesthesia
Neostigmine
Tertiary Care Centers
Paralysis
Neuromuscular Blocking Agents
15 Citations (Scopus)
Anesthesia
Pharmacology
Research
Sugammadex
2014
3 Citations (Scopus)

Analgesia-nociception index

Ledowski, T., 2014, In : British Journal of Anaesthesia. 112, 5, p. 937

Research output: Contribution to journalLetter

27 Citations (Scopus)

Analgesia Nociception Index (ANI) to predict intraoperative haemodynamic changes: Results of a pilot investigation

Ledowski, T., Averhoff, L., Tiong, W. S. & Lee, C., 2014, In : ACTA Anaesthesiologica Scandinavica. 58, 1, p. 74-79

Research output: Contribution to journalArticle

Nociception
Analgesia
Hemodynamics
Heart Rate
Blood Pressure

Analgesia-nociception index Reply

Ledowski, T., May 2014, In : British Journal of Anaesthesia. 112, 5, p. 937-937 1 p.

Research output: Contribution to journalLetter

59 Citations (Scopus)

Retrospective investigation of postoperative outcome after reversal of residual neuromuscular blockade: Sugammadex, neostigmine or no reversal

Ledowski, T., Falke, L., Johnston, F., Gillies, E., Greenaway, M., De Mel, A., Tiong, E. & Phillips, M., 2014, In : European Journal of Anaesthesiology. 31, 8, p. 423-429

Research output: Contribution to journalArticle

Open Access
Delayed Emergence from Anesthesia
Neostigmine
Length of Stay
Neuromuscular Nondepolarizing Agents
Postoperative Nausea and Vomiting
2013
11 Citations (Scopus)
242 Downloads (Pure)

Acute effects of red wine on cytochrome P450 eicosanoids and blood pressure in men

Barden, A., Croft, K., Beilin, L., Phillips, M., Ledowski, T. & Puddey, I., Nov 2013, In : Journal of Hypertension. 31, 11, p. 2195-2202

Research output: Contribution to journalArticle

Open Access
File
Eicosanoids
Wine
Cytochrome P-450 Enzyme System
Blood Pressure
Acids
43 Citations (Scopus)

Analgesia nociception index: Evaluation as a new parameter for acute postoperative pain

Ledowski, T., Tiong, E., Lee, C., Wong, B., Fiori, T. & Parker, N., 2013, In : British Journal of Anaesthesia. 111, 4, p. 627-629

Research output: Contribution to journalArticle

28 Citations (Scopus)

Introduction of sugammadex as standard reversal agent: Impact on the incidence of residual neuromuscular blockade and postoperative patient outcome

Ledowski, T., Hillyard, S., O'Dea, B., Archer, R., Vilas-Boas, F. & Kyle, B., 2013, In : Indian Journal of Anaesthesia. 57, 1, p. 46-51

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Long-term quality of sleep after remifentanil-based anaesthesia: A randomized controlled trial

Wenk, M., Pöpping, D. M., Chapman, G., Grenda, H. & Ledowski, T., 2013, In : British Journal of Anaesthesia. 110, 2, p. 250-257

Research output: Contribution to journalArticle

The 5-Minute Anesthesia Consult: Assessment of Acute Postoperative Pain

Ledowski, T., 2013, Not available. Singh-Radcliff, N. (ed.). United States

Research output: Chapter in Book/Conference paperOther chapter contribution

The 5-Minute Anesthesia Consult: Ciliary Function

Ledowski, T., 2013, Not available. Singh-Radcliff, N. (ed.). United States

Research output: Chapter in Book/Conference paperOther chapter contribution

2012
44 Citations (Scopus)

Effects of acute postoperative pain on catecholamine plasma levels, hemodynamic parameters, and cardiac autonomic control

Ledowski, T., Reimer, M., Chavez, V., Kapoor, V. & Wenk, M., 2012, In : Pain. 153, p. 759-764

Research output: Contribution to journalArticle

Is acute postoperative pain reflected by a change in parasympathetic cardiac tone? Evaluation of the Analgesia Nociception Index

T., L., W.S., T., C., L., B., W., T., F. & N., P., 2012, In : Anaesthesia and Intensive Care. 40, 6, p. 1064

Research output: Contribution to journalArticle

Nociception
Acute Pain
Postoperative Pain
Analgesia
Recovery Room
2 Citations (Scopus)

Long-term postoperative quality of sleep after fentanyl- and remifentanil-based anaesthesia - a randomised controlled trial

Pöpping, D. M., Chapman, G., Grenda, H., Ledowski, T. & Wenk, M., Jun 2012, In : European Journal of Anaesthesiology. 29, p. 28-29 2 p.

Research output: Contribution to journalArticle

Fentanyl
Sleep
Anesthesia
Randomized Controlled Trials
Opioid Analgesics
34 Citations (Scopus)

Unrestricted access to sugammadex: Impact on neuromuscular blocking agent choice, reversal practice and associated healthcare costs

Ledowski, T., Hillyard, S., Kozman, A., Johnston, F., Gillies, E., Greenaway, M. & Kyle, B. C., 2012, In : Anaesthesia and Intensive Care. 40, p. 340-343

Research output: Contribution to journalArticle

2011

Introduction of sugammadex: Influence on the incidence of residual paralysis at a tertiary teaching hospital

Ledowski, T., O'Dea, B., Boas, F. V., Archer, R., Hillyard, S. & Kyle, B., 2011, In : Anaesthesia and Intensive Care. 39, 5, p. 963

Research output: Contribution to journalArticle

Tertiary Care Centers
Teaching Hospitals
Paralysis
Recovery Room
Neostigmine
7 Citations (Scopus)
3 Citations (Scopus)

The impact of increased availability of sugammadex on perioperative management of neuromuscular blockade in an Australian teaching hospital.

Hillyard, S., Kyle, B., O'Dea, B., Boas, F. V., Archer, R. & Ledowski, T., Sep 2011, In : Anaesthesia. 66, p. 52-52 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

18 Citations (Scopus)
2010
10 Citations (Scopus)
24 Citations (Scopus)

Monitoring of intra-operative nociception: skin conductance and surgical stress index versus stress hormone plasma levels

Ledowski, T., Pascoe, M., Ang, B., Schmarbeck, T., Clarke, M., Fuller, C. & Kapoor, V., 2010, In : Anaesthesia. 65, 10, p. 1001-1006

Research output: Contribution to journalArticle

11 Citations (Scopus)

Successful use of rocuronium and sugammadex in an anticipated difficult airway scenario

Mcternan, C. N., Rapeport, D. A. & Ledowski, T., 2010, In : Anaesthesia & Intensive Care. 38, p. 390-392

Research output: Contribution to journalReview article

2009
19 Citations (Scopus)

Effects of clonidine and midazolam premedication on bispectral index and recovery after elective surgery

Paris, A., Kaufmann, M., Tonner, P. H., Renz, P., Lemke, T., Ledowski, T., Scholz, J. & Bein, B., 2009, In : European Journal of Anaesthesiology. 26, 7, p. 603-610

Research output: Contribution to journalArticle

Premedication
Midazolam
Clonidine
Placebos
Pain Measurement
20 Citations (Scopus)

Induction dose of propofol in patients using cannabis

Flisberg, P. E., Paech, M., Shah, T., Ledowski, T., Kurowski, I. & Parsons, R., 2009, In : European Journal of Anaesthesiology. 26, 3, p. 192-195

Research output: Contribution to journalArticle

Propofol
Cannabis
Laryngeal Masks
Unconsciousness
Anesthetics
46 Citations (Scopus)

Monitoring electrical skin conductance: A tool for the assessment of postoperative pain in children

Hullett, B., Chambers, N., Preuss, J., Zamudio, I., Lange, J., Pascoe, M. & Ledowski, T., 2009, In : Anesthesiology. 111, 3, p. 513-7

Research output: Contribution to journalArticle

Postoperative Pain
Skin
Pain Measurement
Pediatrics
Pain
57 Citations (Scopus)

Monitoring of sympathetic tone to assess postoperative pain : skin conductance vs surgical stress index

Ledowski, T., Ang, Y. L. B., Schmarbeck, T. & Rhodes, J., 2009, In : Anaesthesia. 64, 7, p. 727-731

Research output: Contribution to journalArticle

Postoperative Pain
Pain
Skin
Recovery Room
Aptitude
9 Citations (Scopus)

The effects of neostigmine and glycopyrrolate on skin conductance as a measure of pain

Ledowski, T., Preuss, J. M. H. & Schug, S., 2009, In : European Journal of Anaesthesiology. 26, 9, p. 777-781

Research output: Contribution to journalArticle

Glycopyrrolate
Neostigmine
Pain
Skin
Recovery Room
9 Citations (Scopus)

Vitamin E Supplementation and Hepatic Drug Metabolism in Humans

Clarke, M., Burnett, J., Wu, J., Hodgson, J., Ledowski, T., Puddey, I. & Croft, K., 2009, In : Journal of Cardiovascular Pharmacology. 54, 6, p. 491-96

Research output: Contribution to journalArticle

Tocopherols
Vitamin E
Midazolam
Cytochrome P-450 CYP3A
Liver

What should the researchers do when they are not able to reproduce their own findings? Reply

Ledowski, T., 2009, In : Anaesthesia. 64, p. 782-783

Research output: Contribution to journalLetter