Tea Shavlakadze

Associate Professor, BBiol CandSci Tbilisi SU, PhD W.Aust.

  • The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1482 Citations
  • 23 h-Index
20032018
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Research Output 2003 2018

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Article
2018
5 Citations (Scopus)

Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T- and B-cell zones

Tomay, F., Wells, K., Duong, L., Tsu, J. W., Dye, D. E., Radley-Crabb, H., Grounds, M. D., Shavlakadze, T., Metharom, P., Nelson, D. J. & Jackaman, C., 30 Mar 2018, In : Immunology and Cell Biology.

Research output: Contribution to journalArticle

Lymphoid Tissue
Neutrophils
B-Lymphocytes
Lymph Nodes
Spleen
2 Citations (Scopus)
Vesicular Glutamate Transport Protein 1
Motor Neurons
Spinal Cord
Carisoprodol
Sarcopenia
2017
6 Citations (Scopus)

IGF1 stimulates greater muscle hypertrophy in the absence of myostatin in male mice

Hennebry, A., Oldham, J., Shavlakadze, T., Grounds, M. D., Sheard, P., Fiorotto, M. L., Falconer, S., Smith, H. K., Berry, C., Jeanplong, F., Bracegirdle, J., Matthews, K., Nicholas, G., Senna-Salerno, M., Watson, T. & McMahon, C. D., Aug 2017, In : Journal of Endocrinology. 234, 2, p. 187-200 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Sarcopenia
Sciatic Nerve
Axons
Skeletal Muscle
S100 Proteins
2016
15 Citations (Scopus)
228 Downloads (Pure)

A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice

Krishnan, V. S., White, Z., Mcmahon, C. D., Hodgetts, S., Fitzgerald, M., Shavlakadze, T., Harvey, A. & Grounds, M., 1 May 2016, In : Journal of Neuropathology and Experimental Neurology. 75, 5, p. 464-478

Research output: Contribution to journalArticle

Open Access
File
Sarcopenia
Sciatic Nerve
Axons
Choline O-Acetyltransferase
Peripheral Nerves
19 Citations (Scopus)
Hypertrophy
Muscles
Quadriceps Muscle
Skeletal Muscle
Extremities
18 Citations (Scopus)
Long Noncoding RNA
MicroRNAs
Skeletal Muscle
Untranslated RNA
Growth
30 Citations (Scopus)
Open Access
Sarcopenia
Autophagy
Inbred C57BL Mouse
Exercise
Muscles
2015
27 Citations (Scopus)
256 Downloads (Pure)
Open Access
File
PTEN Phosphohydrolase
Phosphorylation
Oxidative stress
Skeletal Muscle Fibers
Sulfhydryl Compounds
2014
17 Citations (Scopus)

Lifelong exercise and locally produced insulin-like growth factor-1 (IGF-1) have a modest influence on reducing age-related muscle wasting in mice

Mcmahon, CD., Chai, R., Crabb, H., Watson, T., Matthews, KG., Sheard, P., Soffe, Z., Grounds, M. & Shavlakadze, T., Dec 2014, In : Scandinavian Journal of Medicine and Science in Sports. 24, 6, p. e423-e435

Research output: Contribution to journalArticle

Somatomedins
Muscles
Skeletal Muscle
Sarcopenia
Quadriceps Muscle
28 Citations (Scopus)

Lipid accumulation in dysferlin-deficient muscles

Grounds, M., Terrill, J., Radley-Crabb, H., Robertson, T., Papadimitriou, J., Spuler, S. & Shavlakadze, T., 2014, In : American Journal of Pathology. 184, 6, p. 1668-1676

Research output: Contribution to journalArticle

Muscular Diseases
Adipocytes
Psoas Muscles
Lipogenesis
Lipids
33 Citations (Scopus)
Sarcopenia
Denervation
Muscle
Skeletal Muscle
Ribosomal Protein S6
18 Citations (Scopus)
skeletal muscle
Muscular Dystrophies
Optical Coherence Tomography
attenuation coefficients
mice
5 Citations (Scopus)
256 Downloads (Pure)

Protein thiol oxidation does not change in skeletal muscles of aging female mice

Tohma, H., El-Shafey, A., Croft, K., Shavlakadze, T., Grounds, M. & Arthur, P., Feb 2014, In : Biogerontology. 15, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

Open Access
File
2013
32 Citations (Scopus)

Impact of fasting on the rhythmic expression of myogenic and metabolic factors in skeletal muscle of adult mice

Shavlakadze, T., Anwari, T., Soffe, Z., Cozens, G., Mark, P., Gondro, C. & Grounds, M., 1 Jul 2013, In : American Journal of Physiology- Cell Physiology. 305, 1, p. C26-C35

Research output: Contribution to journalArticle

Open Access
132 Citations (Scopus)

New horizons in the pathogenesis, diagnosis and management of sarcopenia

Sayer, A. A., Robinson, S. M., Patel, H. P., Shavlakadze, T., Cooper, C. & Grounds, M., 2013, In : Age and Ageing. 42, 2, p. 145-150

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Short-term feed deprivation rapidly induces the protein degradation pathway in skeletal muscles of young mice

Shavlakadze, T., Soffe, Z., Anwari, T., Cozens, G. & Grounds, M., 2013, In : Journal of Nutrition. 143, 4, p. 403-409

Research output: Contribution to journalArticle

Open Access
50 Citations (Scopus)

Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice

Jackaman, C., Radley-Crabb, H. G., Soffe, Z., Shavlakadze, T., Grounds, M. & Nelson, D. J., 2013, In : Aging Cell. 12, 3, p. 345-357

Research output: Contribution to journalArticle

2012
77 Citations (Scopus)

An HMGA2-IGF2BP2 Axis Regulates Myoblast Proliferation and Myogenesis

Li, Z., Gilbert, J. A., Zhang, Y., Zhang, M., Qiu, Q., Ramanujan, K., Shavlakadze, T., Eash, J. K., Scaramozza, A., Goddeeris, M. M., Kirsch, D. G., Campbell, K. P., Brack, A. S. & Glass, D. J., 2012, In : Developmental Cell. 23, 6, p. 1176-1188

Research output: Contribution to journalArticle

Open Access
2011
31 Citations (Scopus)
19 Citations (Scopus)

Quantification of Ceroid and Lipofuscin in Skeletal Muscle

Tohma, H., Hepworth, A., Shavlakadze, T., Grounds, M. & Arthur, P., 2011, In : Journal of Histochemistry & Cytochemistry. 59, 8, p. 769-779

Research output: Contribution to journalArticle

93 Citations (Scopus)

Striking Denervation of Neuromuscular Junctions without Lumbar Motoneuron Loss in Geriatric Mouse Muscle

Chai, R., Vukovic, J., Dunlop, S., Grounds, M. & Shavlakadze, T., 2011, In : PLoS One. 6, 12, p. 11 pages

Research output: Contribution to journalArticle

Open Access
2010
55 Citations (Scopus)

A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo

Shavlakadze, T., Chai, R., Maley, K., Cozens, G., Grounds, G., Winn, N., Rosenthal, N. & Grounds, M., 2010, In : Journal of Cell Science. 123, p. 960-971

Research output: Contribution to journalArticle

76 Citations (Scopus)
2008
40 Citations (Scopus)
Grafts
Muscle
Regeneration
Skeletal Muscle
Transplants
55 Citations (Scopus)
Somatomedins
Skeletal Muscle
Tumor Necrosis Factor-alpha
Necrosis
Inbred mdx Mouse
31 Citations (Scopus)

Muscle-specific overexpression of IGF-I improves E-C coupling in skeletal muscle fibers from dystrophic mdx mice

Schertzer, J. D., Van Der Poel, C., Shavlakadze, T., Grounds, M. & Lynch, G. S., 2008, In : American journal of physiology : cell physiology. 294, 1, p. C161-C168

Research output: Contribution to journalArticle

Inbred mdx Mouse
Excitation Contraction Coupling
Skeletal Muscle Fibers
Insulin-Like Growth Factor I
Muscles
60 Citations (Scopus)
Oxidative Stress
Muscles
MAP Kinase Kinase Kinase 5
Therapeutics
NF-kappa B
2006
51 Citations (Scopus)
Meats
Anura
Meat
Muscle
Skeletal Muscle
19 Citations (Scopus)

Rskα-actin/hIGF-1 transgenic mice with increased IGF-I in skeletal muscle and blood: Impact on regeneration, denervation and muscular dystrophy

Shavlakadze, T., Boswell, J. M., Burt, D. W., Asante, E. A., Tomas, F. M., Davies, M. J., White, J. D., Grounds, M. & Goddard, C., 2006, In : Growth Hormone & IGF Research. 16, 3, p. 157-173

Research output: Contribution to journalArticle

Muscular Dystrophies
Denervation
Insulin-Like Growth Factor I
Transgenic Mice
Actins
2005
37 Citations (Scopus)

Insulin-like growth factor I slows the rate of denervation induced skeletal muscle atrophy

Shavlakadze, T., White, J. D., Davies, M., Hoh, J. F. Y. & Grounds, M., 2005, In : Neuromuscular Disorders. 15, 2, p. 139-146

Research output: Contribution to journalArticle

Muscular Atrophy
Denervation
Insulin-Like Growth Factor I
Skeletal Muscle
Atrophy
112 Citations (Scopus)

Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle

Shavlakadze, T., Winn, N., Rosenthal, N. & Grounds, M., 2005, In : Growth Hormone & IGF Research. 15, 1, p. 4-18

Research output: Contribution to journalArticle

Insulin-Like Growth Factor I
Transgenic Mice
Skeletal Muscle
Protein Isoforms
Transgenes
45 Citations (Scopus)
Biological Assay
Cytokines
Inflammation
Transplants
Muscles
2004
27 Citations (Scopus)
Insulin-Like Growth Factor I
Transgenic Mice
Regeneration
Skeletal Muscle
Transplants
84 Citations (Scopus)

Targeted expression of insulin-like growth factor-1 reduces early myofiber necrosis in dystrophic mdx mice

Shavlakadze, T., White, J., Hoh, J. F. Y., Rosenthal, N. & Grounds, M., 2004, In : Molecular Therapy. 10, 5, p. 829-843

Research output: Contribution to journalArticle

Open Access
Inbred mdx Mouse
Somatomedins
Necrosis
Muscles
Evans Blue