Stuart Hodgetts

Dr, BSc PhD Essex

  • The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1078 Citations
  • 20 h-Index
19952020

Research output per year

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Personal profile

Biography

Dr. Stuart Hodgetts has extensive knowledge and expertise in cell based transplantation therapies and has been devoted to this area of research since 1998. Previous postdoctoral work includes, 2.5yrs at the Oklahoma Medical Research Foundation, USA (immunological gene transcription), 7yrs in the Muscle Research Team at the School of Anatomy & Human Biology, (ANHB) at UWA (myoblast transfer therapy for Duchenne muscular dystrophy). In 2003, through collaboration with Giles Plant, SH has changed fields to apply his expertise to spinal cord repair using adult mesenchymal human bone marrow stromal stem cells.

Roles and responsibilities

SH is also Director of Tissue Culture Facilities at ANHB (UWA), Treasurer UWA Research Staff Association, Executive Committee Member (ANHB), Assistant Health & Safety Officer (ANHB), Focus Group member for research restructure, (ANHB), and Founding committee member of the Biology Society, Essex University, UK.

Funding overview

SH has been CI on grants totalling $1,424,781 since 2001-2007. He currently is funded by the Victorian Neurotrauma Initiative and the Neurotrauma Research Program (NRP) of WA.

Current projects

Human Bone Marrow Stromal Cells in spinal cord repair

Teaching overview

• Assistant lecturer and demonstrator for 325 Neurobiology undergraduates at the School of Anatomy and Human Biology, University of Western Australia, Nedlands, Western Australia (2006-2008)
• Tissue Engineering Workshop (Collaboration with Oron Catts & Ionat Zurr – Symbiotica) AV06 Festival, United Kingdom, 2006
• 325 Neuroscience (for final year Human Biology undergraduates at the School of Anatomy and Human Biology, University of Western Australia, Nedlands, Western Australia) (2005-present)
• Lecturer and demonstrator in 313 Molecular Biology (DNA/RNA isolation and purification, Southern and Northern blotting, RFLP analysis, plasmid construction, PCR and sequencing) and 313 Tissue Culture (primary and established cell line culture, monoclonal antibody production) for final year Human Biology undergraduates at the School of Anatomy and Human Biology, University of Western Australia, Nedlands, Western Australia (1998-present). SPOT tested.
• Lecturer and demonstrator in 308 Developmental Biology for final year undergraduates at the School of Anatomy and Human Biology, University of Western Australia, Nedlands, Western Australia (Jan 2003 and 2004).
• Lecturer and demonstrator in Developmental Biology and Reproduction. Biological Sciences final year undergraduates and Nursing students at Essex University, U.K. (1993).
• Special tutor/examiner for overseas student for the University Overseas Department in Biology (Oct 1991-March 1992).
• Assistant lecturer. Immunology Conference, British Society of Immunology, University of Essex, U.K. (1990).

Research

Spinal Cord Repair
Bone Marrow Stromal Cells
Immunotherapy
Tissue Engineering

Research expertise keywords

  • Stem cell transplantation
  • Gene therapy
  • Cellular mechanisms of repair
  • Central nervous system regeneration
  • Human bone marrow stromal cell transplantation
  • Modulation of host immune responses to cell transplantation therapies
  • Neurotrauma and neurodegeneration
  • Neurotrophic factors and cell death
  • Regenerative neuroscience
  • Spinal cord injury and regeneration
  • Spinal cord injury and repair
  • Stem cells
  • Inducible Pluripotent Stem Cells (iPSCs)
  • Tissue engineering
  • Viral vectors
  • Multi Electrode Array studies

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Research Output

Regeneration of adult rat sensory and motor neuron axons through chimeric peroneal nerve grafts containing donor Schwann cells engineered to express different neurotrophic factors

Godinho, M. J., Staal, J. L., Krishnan, V. S., Hodgetts, S. I., Pollett, M. A., Goodman, D. P., Teh, L., Verhaagen, J., Plant, G. W. & Harvey, A. R., Aug 2020, In : Experimental Neurology. 330, 113355.

Research output: Contribution to journalArticle

  • 4 Citations (Scopus)

    Cortical AAV-CNTF gene therapy combined with intraspinal mesenchymal precursor cell transplantation promotes functional and morphological outcomes after spinal cord injury in adult rats

    Hodgetts, S., Yoon, Y. H., Fogliani, A., Akinpelu, E., Baron-Heeris, D., Houwers, I., Wheeler, L., Majda, B., Santhakumar, S., Lovett, S., Duce, E., Pollett, M., Wiseman, T., Fehily, B. & Harvey, A., 6 Aug 2018, In : Neural Plasticity. 2018, 15 p., 9828725.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Citations (Scopus)

    INDUCED PLURIPOTENT STEM CELL MODELS OF RETINITIS PIGMENTOSA CAUSED BY RP1 MUTATION

    Moon, S. Y., Zhang, X., Zhang, D., Chen, S-C., De Roach, J., Lamey, T., Mellough, C., Hodgetts, S., Chen, F. & McLenachan, S., Nov 2018, In : Clinical and Experimental Ophthalmology. 46, p. 127-127 1 p., 109.

    Research output: Contribution to journalAbstract/Meeting Abstract

    Open Access
  • 42 Citations (Scopus)

    Projects