Stuart Hodgetts

Dr, BSc PhD Essex

  • The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile

Biography

Associate Professor Stuart Hodgetts has extensive knowledge and expertise in cell and stem cell-based transplantation therapies. Previous postdoctoral work includes, 2.5yrs at the Oklahoma Medical Research Foundation, USA (immunological gene transcription), and 7yrs in the Muscle Research Team at the School of Anatomy & Human Biology, (ANHB) at UWA (cell transplantation therapy for Duchenne muscular dystrophy). Since 2003, he has focussed his expertise toward spinal cord repair using clinical grade adult human mesenchymal stem cells, as well as in combination with gene therapy (to induce plasticity), in vivo reprogramming, tissue engineering (scaffolds and self-assembling peptides), neuroprotection, immunomodulation of the host immune response, and non-invasive therapies such as red/near infra-red light and repetitive transcranial magnetic stimulation. His laboratory provides a core facility for collaboration with other neuroscientists and engineers seeking to apply regenerative therapies in the spinal cord

Roles and responsibilities

SH is also;

  • UWA representative on the WA Animal Resources Authority (ARA) – 2019 – present
  • Chair, Animal Users Committee, UWA (2007 - present)
  • Secretary of the UWA Research Staff Association (2018 - present)
  • Committee member of the UWA Research Staff Association (2002 (inaugural) - present)
  • WA Representative on the working committee for the Australian Spinal Cord Injury Collaboration (Jan 2020 - present)
  • "Honorary member" & consultant for Art & Science Collaborative Research Laboratory Symbiotica (SymbioticA Research Group), UWA (http://www.symbiotica.uwa.edu.au/).

Funding overview

SH has been CI on grants totalling $5,231,680 since 2001.

Funding includes, NHMRC, ARC, Victorian Neurotrauma Initiative, Perron Institute and the Neurotrauma Research Program (NRP) of WA.

Current projects

SH currently focuses on stem cell based transplants and gene therapy for repair after SCI, in combination with other approaches that include; induced pluripotent stem cell technology, in vivo reprogramming, tissue and bio-engineering, neuroprotective peptides, immunomodulation and non-invasive therapies such as red/near infra-red as well as repetitive transcranial magnetic stimulation therapies.  He currently holds appointments as the Director of Spinal Cord Repair Laboratory at UWA and as Senior Research Fellow at the Perron Institute for Neurological and Translational Science.

Teaching overview

• Unit coordinator and lecturer for;

NEUR3301 and NEUR3302 (Advanced Neuroscience)

ANHB3323 (Cells tissues and Development)

ANHB3321 (Biological Anthropology: Genes and Society)

NEUR4010 (Modern Research Tools in Neuroscience)

Guest lecturer for ANHB3310 & ANHB3320 (Human Biology: Applications and Investigations)

Guest lecturer for Curtin University GENE6001 (v.1) Stem Cell Biology and Regenerative Medicine

 

Supervisor for ;

Honours Students (31 from 1999)

Masters Students (8 since 2000)

PhD Students (17 from 2001 - currently 9 PhD students)

Research

Spinal Cord Repair

Adult Stem Cells (BMSCs, MPCs, iPSCs)
Gene Therapy (AAV)

In vivo Reprogramming

Tissue Engineering (Self Assembling Peptides, Scaffolds, Nanotechnology)

Neuroprotective Peptides

Photobiomodulation

Repetitive Transcranial Magnetic Stimulation
Immunotherapy

Mathematical Models of Spinal Cord Injury

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

External positions

Senior Research Fellow, Perron Institute for Neurological and Translational Sciences

2015 → …

Research expertise keywords

  • Stem cell transplantation
  • Gene therapy
  • Cellular mechanisms of repair
  • Central nervous system regeneration
  • Human bone marrow stromal cell transplantation
  • Modulation of host immune responses to cell transplantation therapies
  • Neurotrauma and neurodegeneration
  • Neurotrophic factors and cell death
  • Regenerative neuroscience
  • Spinal cord injury and regeneration
  • Spinal cord injury and repair
  • Stem cells
  • Inducible Pluripotent Stem Cells (iPSCs)
  • Tissue engineering
  • Viral vectors
  • Multi Electrode Array studies

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