Steve Wilton

Professor, BSc PhD Adel.

  • 6836 Citations
  • 40 h-Index
1992 …2019
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Personal profile

Keywords

  • Genetic therapies
  • Molecular medicine
  • Muscular dystrophy
  • Neuroscience: genetics

Fingerprint Dive into the research topics where Steve Wilton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 18 Similar Profiles
Dystrophin Medicine & Life Sciences
Exons Medicine & Life Sciences
Antisense Oligonucleotides Medicine & Life Sciences
Duchenne Muscular Dystrophy Medicine & Life Sciences
Morpholinos Medicine & Life Sciences
Genes Medicine & Life Sciences
Inbred mdx Mouse Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Research Output 1992 2019

A Common Deep Intronic Mutation Causing Collagen VI-Related Muscular Dystrophy: Validation of Splice-Modulating Approaches In Vitro and Development of a Mouse Model

Bolduc, V., Foley, A. R., Solomon-Degefa, H., Sarathy, A., Donkervoort, S., Hu, Y., Chen, G. S., Nalls, M., Zhou, H., Aguti, S., Cummings, B. B., Lek, M., Tukiainen, T., Marshall, J. L., Regev, O., Marek-Yagel, D., Sarkozy, A., Butterfield, R. J., Jou, C., Jimenez-Mallebrera, C. & 15 othersLi, Y., Cheng, J., Garrett, L., Gartioux, C., Mamchaoui, K., Allamand, V., Gualandi, F., Ferlini, A., Hanssen, E., Wilton, S. D., Lamande, S. R., MacArthur, D. G., Wagener, R., Muntoni, F. & Bonnemann, C. G., 22 Apr 2019, In : Molecular Therapy. 27, 4, p. 304-304 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

1 Citation (Scopus)

Antisense-mediated splice intervention to treat human disease: the odyssey continues

Pitout, I., Flynn, L. L., Wilton, S. D. & Fletcher, S., 22 May 2019, In : F1000Research. 8, 710.

Research output: Contribution to journalReview article

Open Access
Oligonucleotides
Nucleic Acids
Pharmaceutical Preparations
Safety
Degradation
6 Citations (Scopus)

A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies

COL6A1 Intron 11 Study Group, 21 Mar 2019, In : JCI Insight. 4, 6, e124403.

Research output: Contribution to journalArticle

Muscular Dystrophies
Collagen
Clustered Regularly Interspaced Short Palindromic Repeats
RNA Sequence Analysis
Precision Medicine

Breakpoint junction features of seven DMD deletion mutations

Keegan, N. P., Wilton, S. D. & Fletcher, S., 1 Dec 2019, In : Human Genome Variation. 6, 1, 39.

Research output: Contribution to journalArticle

Open Access
Duchenne Muscular Dystrophy
Sequence Deletion
Bioinformatics
Muscle
Exons

Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides

Aung-Htut, M. T., Comerford, I., Johnsen, R., Foyle, K., Fletcher, S. & Wilton, S. D., 10 Sep 2019, In : Scientific Reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Integrin alpha Chains
Antisense Oligonucleotides
RNA Precursors
Disease Progression
Exons

Datasets

Data from: Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction

Mishra, M. K. (Creator), Loro, E. (Creator), Sengupta, K. (Creator), Wilton, S. (Creator), Khurana, T. S. (Creator), Figshare, 16 Sep 2017

Dataset

Projects 1996 2016