• The University of Western Australia (M516), 35 Stirling Highway,

    6009 Perth

    Australia

  • 328 Citations
  • 12 h-Index
20112020
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Research Output 2011 2019

2019
Glycocalyx
Hospital Emergency Service
Sepsis
Randomized Controlled Trials
Biomarkers
Near-Infrared Spectroscopy
Sepsis
Oxygen
Organ Dysfunction Scores
Hospital Emergency Service
2018
175 Downloads (Pure)
File
Hospital Emergency Service
Sepsis
Biomarkers
Blood Vessels
Oxygen
5 Citations (Scopus)
Syndecan-1
Glycocalyx
Respiratory Insufficiency
Sepsis
Pneumonia

Liberal or restricted fluid resuscitation in critical illness: Shifting the needle back towards equipoise

Macdonald, S. P. J. & Shapiro, N. I., Aug 2018, In : Emergency Medicine Australasia. 30, 4, p. 446-447 2 p.

Research output: Contribution to journalEditorial

Open Access
15 Citations (Scopus)

Liberal Versus Restrictive Intravenous Fluid Therapy for Early Septic Shock: Rationale for a Randomized Trial

CLOVERS Protocol Committee and NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) Network Investigators, 1 Oct 2018, In : Annals of Emergency Medicine. 72, 4, p. 457-466 10 p.

Research output: Contribution to journalArticle

Open Access
Fluid Therapy
Septic Shock
Resuscitation
Perfusion
National Heart, Lung, and Blood Institute (U.S.)
1 Citation (Scopus)
Open Access
Neutrophil Activation
Anaphylaxis
Innate Immunity
Myeloid Cells
Toll-Like Receptor 4
Emergency Medicine
Research
Cardiology
Research Personnel
Wounds and Injuries
6 Citations (Scopus)

Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial

REFRESH trial investigators, 31 Oct 2018, In : Intensive Care Medicine.

Research output: Contribution to journalArticle

Resuscitation
Hypotension
Sepsis
Randomized Controlled Trials
Hospital Emergency Service
2 Citations (Scopus)

Review article: Sepsis in the emergency department – Part 3: Treatment

Williams, J. M., Keijzers, G., Macdonald, S. P. J., Shetty, A. & Fraser, J. F., 1 Apr 2018, In : EMA - Emergency Medicine Australasia. 30, 2, p. 144-151 8 p.

Research output: Contribution to journalReview article

Hospital Emergency Service
Sepsis
Guidelines
Anti-Bacterial Agents
Quality of Health Care
8 Citations (Scopus)

Review article: Sepsis in the emergency department – Part 2: Investigations and monitoring

Shetty, A., Macdonald, S. P. J., Keijzers, G., Williams, J. M., Tang, B., de Groot, B., Thompson, K., Fraser, J. F., Finfer, S., Bellomo, R. & Iredell, J., 1 Feb 2018, In : EMA - Emergency Medicine Australasia. 30, 1, p. 4-12 9 p.

Research output: Contribution to journalReview article

Hospital Emergency Service
Sepsis
Biomarkers
Infection
Bacterial DNA

Sepsis in the older person: The ravages of time and bacteria

Burkett, E., Macdonald, S. P. J., Carpenter, C. R., Arendts, G., Hullick, C., Nagaraj, G. & Osborn, T. M., 1 Apr 2018, In : EMA - Emergency Medicine Australasia. 30, 2, p. 249-258 10 p.

Research output: Contribution to journalArticle

2017
6 Citations (Scopus)
Glycocalyx
Emergency Treatment
Syndecan-1
Hospital Emergency Service
Hyaluronic Acid
11 Citations (Scopus)

Lactate ≥2 mmol/L plus qSOFA improves utility over qSOFA alone in emergency department patients presenting with suspected sepsis

Shetty, A., MacDonald, S. P. J., Williams, J. M., van Bockxmeer, J., de Groot, B., Esteve Cuevas, L. M., Ansems, A., Green, M., Thompson, K., Lander, H., Greenslade, J., Finfer, S. & Iredell, J., 1 Dec 2017, In : EMA - Emergency Medicine Australasia. 29, 6, p. 626-634 9 p.

Research output: Contribution to journalArticle

Hospital Emergency Service
Lactic Acid
Sepsis
Organ Dysfunction Scores
Confidence Intervals
8 Citations (Scopus)
227 Downloads (Pure)

Neutrophil activation during acute human anaphylaxis: Analysis of MPO and sCD62L

Francis, A., Bosio, E., Stone, S. F., Fatovich, D. M., Arendts, G., Nagree, Y., Macdonald, S. P. J., Mitenko, H., Rajee, M., Burrows, S. & Brown, S. G. A., 13 Jan 2017, In : Clinical and Experimental Allergy. n/a, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
Neutrophil Activation
Anaphylaxis
Tryptases
Histamine
Peroxidase
11 Citations (Scopus)
Resistin
Sepsis
Septic Shock
Vascular Cell Adhesion Molecule-1
Intercellular Adhesion Molecule-1
16 Citations (Scopus)

REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): Study protocol for a pilot randomised controlled trial

Macdonald, S. P. J., Taylor, D. M., Keijzers, G., Arendts, G., Fatovich, D. M., Kinnear, F. B., Brown, S. G. A., Bellomo, R., Burrows, S., Fraser, J. F., Litton, E., Ascencio-Lane, J. C., Anstey, M., McCutcheon, D., Smart, L., Vlad, I., Winearls, J. & Wibrow, B., 29 Aug 2017, In : Trials. 18, 1, 399.

Research output: Contribution to journalArticle

Open Access
Resuscitation
Hypotension
Sepsis
Randomized Controlled Trials
Biomarkers
9 Citations (Scopus)

Review article: Sepsis in the emergency department – Part 1: Definitions and outcomes

Macdonald, S. P. J., Williams, J. M., Shetty, A., Bellomo, R., Finfer, S., Shapiro, N. & Keijzers, G., 1 Dec 2017, In : EMA - Emergency Medicine Australasia. 29, 6, p. 619-625 7 p.

Research output: Contribution to journalReview article

Hospital Emergency Service
Sepsis
Accidental Falls
Routine Diagnostic Tests
Survivors
3 Citations (Scopus)
100 Downloads (Pure)
Open Access
File
Tryptases
Anaphylaxis
Hospital Emergency Service
Shock
Sensitivity and Specificity
2016

ASCIA-P36: NEUTROPHIL ACTIVATION DURING ANAPHYLAXIS

Francis, A., Bosio, E., Stone, S., Neil, C., Fatovich, D., Arendts, G., Nagree, Y., Macdonald, S., Mitenko, H., Rajee, M., Burrows, S. & Brown, S., 1 Sep 2016, In : Internal Medicine Journal. 46, S4, p. 16-16

Research output: Contribution to journalAbstract/Meeting Abstract

3 Citations (Scopus)

Sepsis Early Alert Tool: Early recognition and timely management in the emergency department

Idrees, M., Macdonald, S. P. J. & Kodali, K., 2016, In : Emergency Medicine Australasia. 28, 4, p. 399-403 5 p.

Research output: Contribution to journalArticle

The TARGET pain study: Lessons from a painful marathon

Thom, O. N. N., Keijzers, G., McD Taylor, D., Fatovich, D. M., Finucci, D. P. P., Furyk, J., Jin, S-W. W., Macdonald, S. P. J., Mitenko, H. M. A. M. A., Richardson, J. R. R., Ting, J. Y. S. Y. S., Gibbs, C. R. R. & Chalkley, D. R. R., 2016, In : Emergency Medicine Australasia. n/a, p. 1-4 4 p.

Research output: Contribution to journalArticle

Emergency Medicine
Pain
Multicenter Studies
Research Personnel
Research
2015
12 Citations (Scopus)

Best-practice pain management in the emergency department: A cluster-randomised, controlled, intervention trial

Taylor, D. M., Fatovich, D., Finucci, D. P., Furyk, J., Jin, S-W., Keijzers, G., Macdonald, S., Mitenko, H., Richardson, J. R., Ting, J. Y. S., Thom, O. N., Ugoni, A. M., Hughes, J. A., Bost, N., Ward, M. L., Gibbs, C. R., Macdonald, E. & Chalkley, D. R., 2015, In : Emergency Medicine Australasia. 27, p. 549-557

Research output: Contribution to journalArticle

1 Citation (Scopus)

Near-infrared spectroscopy-based microcirculatory assessment in acute atrial fibrillation

Barrett, O. S. H., Macdonald, S. & Playford, D. A., 2015, In : Anaesthesia and Intensive Care. 43, 1, p. 105-110

Research output: Contribution to journalArticle

Near-Infrared Spectroscopy
Atrial Fibrillation
Electric Countershock
Blood Vessels
Ischemia
2014
49 Citations (Scopus)
Open Access
Septic Shock
Hospital Emergency Service
Sepsis
Mortality
Organ Dysfunction Scores

Hyper-dopaminergic ballismus and respiratory dyskinesia treated with intravenous haloperidol

Mclay, S. V. B. & Macdonald, S., 2014, In : EMA - Emergency Medicine Australasia. 26, 6, p. 647-648

Research output: Contribution to journalLetter

12 Citations (Scopus)
12 Citations (Scopus)

Near-infrared spectroscopy in the assessment of suspected sepsis in the emergency department

Macdonald, S. & Brown, S., 2014, In : Emergency Medicine Journal. Online, p. 5pp

Research output: Contribution to journalArticle

21 Citations (Scopus)

Randomized controlled trial of intravenous antivenom versus placebo for latrodectism: The second redback antivenom evaluation (RAVE-II) study

Isbister, G. K., Page, C. B., Buckley, N. A., Fatovich, D., Pascu, O., Macdonald, S., Calver, L. A. & Brown, S., Dec 2014, In : Annals of Emergency Medicine. 64, 6, p. 620-628

Research output: Contribution to journalArticle

Antivenins
Randomized Controlled Trials
Placebos
Pain
Analgesia
13 Citations (Scopus)

Spontaneous pneumothorax; a multicentre retrospective analysis of emergency treatment, complications and outcomes

Brown, S., Ball, E. L., Macdonald, S., Wright, C. A. & Mcd Taylor, D., May 2014, In : Internal Medicine Journal. 44, 5, p. 450-457

Research output: Contribution to journalArticle

Emergency Treatment
Pneumothorax
Drainage
Air
Hospital Emergency Service
31 Citations (Scopus)

Sustained Elevation of Resistin, NGAL and IL-8 Are Associated with Severe Sepsis/Septic Shock in the Emergency Department

Macdonald, S., Stone, S., Neil, C., Van Eeden, P., Fatovich, D., Arendts, G. & Brown, S., 24 Oct 2014, In : PLoS One. 9, 10, p. 1-9

Research output: Contribution to journalArticle

Open Access
resistin
Resistin
Lipocalins
septic shock
Gelatinases
2013
14 Citations (Scopus)

Do risks outweigh benefits in thrombolysis for stroke?

Brown, S., Macdonald, S. & Hankey, G., 2013, In : BMJ: British Medical Journal. 347, 7923, p. Article numberf5215

Research output: Contribution to journalReview article

4 Citations (Scopus)
7 Citations (Scopus)

Stroke care in Australia: why is it still the poor cousin of health care?

Macdonald, S., 2013, In : Medical Journal of Australia. 199, p. 166-167

Research output: Contribution to journalLetter

2012
5 Citations (Scopus)

High-sensitivity cardiac troponin assays for risk stratification and for the diagnosis of acute myocardial infarction

Vasikaran, S., Macdonald, S. & Sikaris, K. A., 2012, In : Annals of Clinical Biochemistry. 49, p. 209-10

Research output: Contribution to journalLetter

3 Citations (Scopus)

Improving stress testing compliance following chest pain presentations to the emergency department

Chung, K., Playford, D. & Macdonald, S., 2012, In : Emergency Medicine Australasia. 24, p. 518-524

Research output: Contribution to journalArticle

23 Citations (Scopus)
Open Access

Thrombolysis in acute ischaemic stroke

Fatovich, D., Macdonald, S. & Brown, S., 2012, In : Lancet. 380, 9845:1053, p. 54-55

Research output: Contribution to journalReview article

2011
17 Citations (Scopus)

Comparison of two clinical scoring systems for emergency department risk stratification of suspected acute coronary syndrome

Macdonald, S., Nagree, Y., Fatovich, D., Flavell, H. L. & Loutsky, F., 2011, In : Emergency Medicine Australasia. 23, p. 717-725

Research output: Contribution to journalArticle