• The University of Western Australia (M519), 35 Stirling Highway,

    6009 Perth

    Australia

  • 244 Citations
  • 10 h-Index
20132020

Research output per year

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Research Output

  • 244 Citations
  • 10 h-Index
  • 17 Article
  • 1 Doctoral Thesis
2020

Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis

Lee, R. G., Gao, J., Siira, S. J., Shearwood, A. M., Ermer, J. A., Hofferek, V., Mathews, J. C., Zheng, M., Reid, G. E., Rackham, O. & Filipovska, A., 24 Jul 2020, In : Journal of Cell Science. 133, 14

Research output: Contribution to journalArticle

Open Access
2019

CirGO: An alternative circular way of visualising gene ontology terms

Kuznetsova, I., Lugmayr, A., Siira, S. J., Rackham, O. & Filipovska, A., 18 Feb 2019, In : BMC Bioinformatics. 20, 1, 84.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

Nicholls, T. J., Spåhr, H., Jiang, S., Siira, S. J., Koolmeister, C., Sharma, S., Kauppila, J. H. K., Jiang, M., Kaever, V., Rackham, O., Chabes, A., Falkenberg, M., Filipovska, A., Larsson, N. G. & Gustafsson, C. M., 5 Dec 2019, In : Molecular Cell. 76, 5, p. 784-796.e6

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Fidelity of translation initiation is required for coordinated respiratory complex assembly

Rudler, D. L., Hughes, L. A., Perks, K. L., Richman, T. R., Kuznetsova, I., Ermer, J. A., Abudulai, L. N., Shearwood, A-M. J., Viola, H. M., Hool, L. C., Siira, S. J., Rackham, O. & Filipovska, A., 20 Dec 2019, In : Science Advances. 5, 12, eaay2118.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

TEFM regulates both transcription elongation and RNA processing in mitochondria

Jiang, S., Koolmeister, C., Misic, J., Siira, S., Kühl, I., Silva Ramos, E., Miranda, M., Jiang, M., Posse, V., Lytovchenko, O., Atanassov, I., Schober, F. A., Wibom, R., Hultenby, K., Milenkovic, D., Gustafsson, C. M., Filipovska, A. & Larsson, N. G., 1 Jun 2019, In : EMBO Reports. 20, 6, 18 p., e48101.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2018
12 Citations (Scopus)

Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins

Spåhr, H., Chia, T., Lingford, J. P., Siira, S. J., Cohen, S. B., Filipovska, A. & Rackham, O., 7 Jun 2018, In : Nature Communications. 9, 1, p. 2212 2212.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly

Perks, K. L., Rossetti, G., Kuznetsova, I., Hughes, L. A., Ermer, J. A., Ferreira, N., Busch, J. D., Rudler, D. L., Spahr, H., Schöndorf, T., Shearwood, A. M. J., Viola, H. M., Siira, S. J., Hool, L. C., Milenkovic, D., Larsson, N. G., Rackham, O. & Filipovska, A., 3 Apr 2018, In : Cell Reports. 23, 1, p. 127-142 16 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2017

Defects in RNA metabolism in mitochondrial disease

Siira, S. J., Shearwood, A. M. J., Bracken, C. P., Rackham, O. & Filipovska, A., 1 Apr 2017, In : International Journal of Biochemistry and Cell Biology. 85, p. 106-113 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
268 Downloads (Pure)

LRPPRC-mediated folding of the mitochondrial transcriptome

Siira, S. J., Spåhr, H., Shearwood, A. M. J., Ruzzenente, B., Larsson, N. G., Rackham, O. & Filipovska, A., 1 Dec 2017, In : Nature Communications. 8, 1, 1532.

Research output: Contribution to journalArticle

Open Access
26 Citations (Scopus)
Open Access
16 Citations (Scopus)

Transcriptome-wide analyses of gene expression in models of disease

Siira, S. J., 2017, (Unpublished)

Research output: ThesisDoctoral Thesis

File
262 Downloads (Pure)
2016

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly

Rackham, O., Busch, J. D., Matic, S., Siira, S., Kuznetsova, I., Atanassov, I., Ermer, J., Shearwood, A-M., Richman, T., Stewart, J. B., Mourier, A., Milenkovic, D., Larsson, N. G. & Filipovska, A., 16 Aug 2016, In : Cell Reports. 16, 7, p. 1874-1890

Research output: Contribution to journalArticle

Open Access
36 Citations (Scopus)

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA

Kühl, I., Miranda, M., Posse, V., Milenkovic, D., Mourier, A., Siira, S. J., Bonekamp, N. A. A., Neumann, U., Filipovska, A., Loguercio Polosa, P., Gustafsson, C. M. M. & Larsson, N-G. G., 2016, In : Science Advances. 2, 8, 14 p., e1600963.

Research output: Contribution to journalArticle

Open Access
30 Citations (Scopus)

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

Metodiev, M. D., Thompson, K., Alston, C. L., Morris, A. A. M., He, L., Assouline, Z., Rio, M., Bahi-Buisson, N., Pyle, A., Griffin, H., Siira, S., Filipovska, A., Munnich, A., Chinnery, P. F., Mcfarland, R., Rötig, A. & Taylor, R. W., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 993-1000

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

Transcriptome-wide effects of a POLR3A gene mutation in patients with an unusual phenotype of striatal involvement

Azmanov, D. N., Siira, S. J., Chamova, T., Kaprelyan, A., Guergueltcheva, V., Shearwood, A-M. J., Liu, G., Morar, B., Rackham, O., Bynevelt, M., Grudkova, M., Kamenov, Z., Svechtarov, V., Tournev, I., Kalaydjieva, L. & Filipovska, A., 2016, In : Human Molecular Genetics. 25, 19, p. 4302-4314 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2015

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

Lagouge, M., Mourier, A., Lee, H. J., Spahr, H., Wai, T., Kukat, C., Silva Ramos, E., Motori, E., Busch, J. D., Siira, S., Kremmer, E., Filipovska, A. & Larsson, N-G., 2015, In : PLoS Genetics. 11, p. 1-19

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)
2013

Mapping of Mitochondrial RNA-Protein Interactions by Digital RNase Footprinting

Liu, G., Mercer, T. R., Shearwood, A-M., Siira, S., Hibbs, M., Mattick, J. S., Rackham, O. & Filipovska, A., 14 Nov 2013, In : Cell Reports. 5, 3, p. 839-848

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
315 Downloads (Pure)