• The University of Western Australia (M560), 35 Stirling Highway,

    6009 Perth

    Australia

  • 1533 Citations
  • 21 h-Index
20052019
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Research Output 2005 2019

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Article
2019

Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissue

Dhamrait, G. K., Panchal, K., Fleury, N. J., Abel, T. N., Ancliffe, M. K., Crew, R. C., Croft, K., Fernandez, B. O., Minnion, M., Hart, P. H., Lucas, R. M., Mark, P. J., Feelisch, M., Weller, R. B., Matthews, V. & Gorman, S., 29 Aug 2019, In : Diabetologia.

Research output: Contribution to journalArticle

Brown Adipose Tissue
Nitric Oxide
Radiation
High Fat Diet
Skin

Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams (female mice)

Smoothy, J., Larcombe, A. N., Chivers, E. K., Matthews, V. B. & Gorman, S., 30 Jan 2019, In : Respiratory Research. 20, 18 p., 21.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
High Fat Diet
Nutrition
Ultraviolet radiation
Liver
Fats
Open Access
Western Australia
Fasting
Radiation
Glucose
Pediatric Obesity
Adiposity
Solar System
breast
Sun
Prostatic Neoplasms
Saliva
Mastication
Assays
Blood
Flow rate
2018
9 Citations (Scopus)

High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

Ghaly, S., Kaakoush, N. O., Lloyd, F., McGonigle, T., Mok, D., Baird, A., Klopcic, B., Gordon, L., Gorman, S., Forest, C., Bouillon, R., Lawrance, I. C. & Hart, P. H., 1 Dec 2018, In : Scientific Reports. 8, 1, 11511.

Research output: Contribution to journalArticle

Open Access
Microbiota
Colitis
Vitamin D
Dextran Sulfate
Inflammatory Bowel Diseases
Allergens
Ovalbumin
Asthma
Virus Diseases
Antigens

Investigating the roles of regulatory T cells, mast cells and interleukin-9 in the control of skin inflammation by vitamin D

Gorman, S., Geldenhuys, S., Weeden, C., Grimbaldeston, M. A. & Hart, P., 1 Apr 2018, In : Archives of Dermatological Research. 310, 3, p. 221-230 10 p.

Research output: Contribution to journalArticle

Interleukin-9
Regulatory T-Lymphocytes
Mast Cells
Vitamin D
Inflammation
2017
1 Citation (Scopus)

High-dose intramuscular vitamin D provides long-lasting moderate increases in serum 25-hydroxyvitamin D levels and shorter-term changes in plasma calcium

Gorman, S., Zafir, M., Lim, E. M., Clarke, M. W., Dhamrait, G., Fleury, N., Walsh, J. P., Kaufmann, M., Jones, G. & Lucas, R. M., 1 Sep 2017, In : Journal of AOAC International. 100, 5, p. 1337-1344

Research output: Contribution to journalArticle

vitamin
vitamin D
Vitamin D
serum
calcium
5 Citations (Scopus)

Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight mice

Fleury, N., Feelisch, M., Hart, P. H., Weller, R. B., Smoothy, J., Matthews, V. B. & Gorman, S., 1 Apr 2017, In : Journal of Endocrinology. 233, 1, p. 81-92 12 p.

Research output: Contribution to journalArticle

Radiation
High Fat Diet
Nitric Oxide
Sunlight
Adiposity
7 Citations (Scopus)

Ultraviolet radiation, Vitamin D and the development of obesity, metabolic syndrome and type-2 diabetes

Gorman, S., Lucas, R. M., Allen-Hall, A., Fleury, N. & Feelisch, M., 2017, In : Photochemical and Photobiological Sciences. 16, 3, p. 362-373 12 p.

Research output: Contribution to journalArticle

calciferol
obesity
Medical problems
Vitamin D
Ultraviolet radiation
5 Citations (Scopus)

Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrity

Gorman, S., Buckley, A. G., Ling, K. M., Berry, L. J., Fear, V. S., Stick, S. M., Larcombe, A. N., Kicic, A. & Hart, P. H., 1 Aug 2017, In : Physiological Reports. 5, 15, p. 1-12 e13371.

Research output: Contribution to journalArticle

Open Access
Vitamin D
Pneumonia
Cholecalciferol
Lung
Diet
2016
4 Citations (Scopus)

A pathogenic role for the integrin CD103 in experimental allergic airways disease

Fear, V. S., Lai, S. P., Zosky, G. R., Perks, K. L., Gorman, S., Blank, F., Von Garnier, C., Stumbles, P. A. & Strickland, D. H., 1 Nov 2016, In : Physiological Reports. 4, 21, e13021.

Research output: Contribution to journalArticle

Open Access
Integrins
Dendritic Cells
Aerosols
Knockout Mice
Ovalbumin
4 Citations (Scopus)
Open Access
Regulatory T-Lymphocytes
Vitamin D
Lymph Nodes
Inflammation
Cholecalciferol
7 Citations (Scopus)
Vitamin D Deficiency
Pyroglyphidae
Pneumonia
Genes
Smooth Muscle
11 Citations (Scopus)

Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific manner

Roggenbuck, M., Anderson, D., Barfod, K. K., Feelisch, M., Geldenhuys, S., Sørensen, S. J., Weeden, C. E., Hart, P. H. & Gorman, S., 2016, In : Respiratory Research. 17, 1, p. 116 116 p.

Research output: Contribution to journalArticle

Open Access
Microbiota
Vitamin D
Lung
Diet
Ovalbumin
2015
9 Citations (Scopus)

Comparing the effects of sun exposure and vitamin D supplementation on vitamin D insufficiency, and immune and cardio-metabolic function: The Sun Exposure and Vitamin D Supplementation (SEDS) Study

Hartley, M., Hoare, S., Lithander, F. E., Neale, R. E., Hart, P., Gorman, S., Gies, P. H. F., Sherriff, J. L., Swaminathan, A., Beilin, L., Mori, T., King, L., Black, L., Marshall, K., Xiang, F., Wyatt, C., King, K., Slevin, T. J., Pandeya, N. & Lucas, R., 2015, In : BMC Public Health. 15, 1, p. 1-9

Research output: Contribution to journalArticle

Open Access
Solar System
Vitamin D
Vitamin D Deficiency
Skin Neoplasms
Serum
157 Downloads (Pure)

Reduced immune responses in chimeric mice engrafted with bone marrow cells from mice with airways inflammation

Scott, N. M., Ng, R. L. X., McGonigle, T. A., Gorman, S. & Hart, P., Nov 2015, In : Inflammation Research. 64, 11, p. 861-873 13 p.

Research output: Contribution to journalArticle

Open Access
File
Bone Marrow Cells
Inflammation
Bone Marrow
Dendritic Cells
Allergens
27 Citations (Scopus)

The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung function

Foong, R., Bosco, A., Jones, A., Gout, A., Gorman, S., Hart, P. & Zosky, G. R., 1 Nov 2015, In : American Journal of Respiratory Cell and Molecular Biology. 53, 5, p. 664-675 12 p.

Research output: Contribution to journalArticle

Open Access
Vitamin D Deficiency
Vitamin D
Smooth Muscle
Muscle
Lung
2014
47 Citations (Scopus)
258 Downloads (Pure)

Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms

Robinson, M., Whitehouse, A., Newnham, J., Gorman, S., Jacoby, P., Holt, B. J., Serralha, M., Tearne, J., Holt, P., Hart, P. & Kusel, M., 1 Jun 2014, In : Archives of Women's Mental Health. 17, 3, p. 213-219

Research output: Contribution to journalArticle

Open Access
File
Postpartum Depression
Vitamin D
Mothers
Pregnancy
Serum
21 Citations (Scopus)

Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow

Scott, N. M., Ng, R. L., Gorman, S., Norval, M., Waithman, J. & Hart, P., Feb 2014, In : Journal of Leukocyte Biology. 95, 2, p. 225-232

Research output: Contribution to journalArticle

Open Access
Dinoprostone
Dendritic Cells
Bone Marrow
Bone Marrow Cells
Myeloid Progenitor Cells
49 Citations (Scopus)

Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D in mice fed a high-fat diet

Geldenhuys, S., Hart, P., Endersby, R., Jacoby, P., Feelisch, M., Weller, R. B. J. B., Matthews, V. & Gorman, S., 2014, In : Diabetes. 63, 11, p. 3759-3769

Research output: Contribution to journalArticle

High Fat Diet
Vitamin D
Obesity
Radiation
Sunlight
33 Citations (Scopus)

Vitamin D and immunity

Lucas, R., Gorman, S., Geldenhuys, S. & Hart, P., 2014, In : F1000Prime Reports. 6, p. 1-11

Research output: Contribution to journalArticle

Vitamin D
Immunity
Vitamin D Deficiency
Physiologic Calcification
Microbiota
26 Citations (Scopus)
Open Access
2013
31 Citations (Scopus)

Altered immunity and dendritic cell activity in the periphery of mice after long-term engraftment with bone marrow from ultraviolet-irradiated mice

Ng, R. L. X., Scott, N. M., Strickland, D., Gorman, S., Grimbaldeston, M. A., Norval, M., Waithman, J. & Hart, P., 2013, In : Journal of Immunology. 190, p. 5471-5484

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice

Ng, R. L. X., Scott, N. M., Bisley, J. L., Lambert, M. J., Gorman, S., Norval, M. & Hart, P., Dec 2013, In : Immunology. 140, 4, p. 399-412

Research output: Contribution to journalArticle

Open Access
Dendritic Cells
Bone Marrow
Immunity
Radiation
Gene Expression
28 Citations (Scopus)

Reversible Control by Vitamin D of Granulocytes and Bacteria in the Lungs of Mice: An Ovalbumin-Induced Model of Allergic Airway Disease

Gorman, S., Weeden, C. E., Tan, D. H. W., Scott, N. M., Hart, J., Foong, R., Mok, D., Stephens, N., Zosky, G. & Hart, P., 2013, In : PLoS One. 8, p. 16pp

Research output: Contribution to journalArticle

Open Access
2012
39 Citations (Scopus)

Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the Absence of Increased 25-Hydroxyvitamin D3 Levels in Male Mice

Gorman, S., Scott, N. M., Tan, D. H. W., Weeden, C. E., Tuckey, R., Bisley, J. L., Grimbaldeston, M. A. & Hart, P., 26 Sep 2012, In : PLoS One. 7, 9, p. e46006.1-12

Research output: Contribution to journalArticle

Open Access
25-hydroxycholecalciferol
Calcifediol
cholecalciferol
Cholecalciferol
immunosuppression
10 Citations (Scopus)

Toward homeostasis: Regulatory dendritic cells from the bone marrow of mice with inflammation of the airways and peritoneal cavity

Scott, N. M., Ng, R. L. X., Strickland, D., Bisley, J. L., Bazely, S. A., Gorman, S., Norval, M. & Hart, P., 2012, In : American Journal of Pathology. 181, 2, p. 535-547

Research output: Contribution to journalArticle

37 Citations (Scopus)

Vitamin D 3 deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway disease

Gorman, S., Tan, D. H. W., Lambert, M. J. M., Scott, N. M., Judge, M. A. & Hart, P., 2012, In : Pediatric Allergy and Immunology. 23, 12, p. 83-87

Research output: Contribution to journalArticle

2011
5 Citations (Scopus)
208 Citations (Scopus)

Vitamin D deficiency causes deficits in lung function and alters lung structure

Zosky, G., Berry, L. J., Elliot, J. G., James, A. L., Gorman, S. & Hart, P., 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 10, p. 1336-1343

Research output: Contribution to journalArticle

2010
45 Citations (Scopus)

1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses

Gorman, S., Judge, M. A., Burchell, J., Turner, D. & Hart, P., 2010, In : Immunology. 130, 2, p. 181-192

Research output: Contribution to journalArticle

12 Citations (Scopus)

Gene regulation by 1,25-dihydroxyvitamin D3 in CD4+CD25+ Cells Is Enabled by IL-2

Gorman, S., Judge, M. A. & Hart, P., 2010, In : Journal of Investigative Dermatology. 130, 10, p. 2368-2376

Research output: Contribution to journalArticle

Open Access
30 Citations (Scopus)

Topical 1,25-dihydroxyvitamin D3 subverts the priming ability of draining lymph node dendritic cells

Gorman, S., Judge, M. A. & Hart, P., 2010, In : Immunology. 131, 3, p. 415-425

Research output: Contribution to journalArticle

37 Citations (Scopus)

Ultraviolet irradiation of mice reduces the competency of bone marrow-derived CD11c+ cells via an indomethacin-inhibitable pathway

Ng, R., Bisley, J. L., Gorman, S., Norval, M. & Hart, P., 2010, In : Journal of Immunology. 185, 12, p. 7207-715

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

UV exposure and protection against allergic airways disease

Gorman, S., Mcglade, J. P., Lambert, M. J., Strickland, D., Thomas, J. A. & Hart, P., 2010, In : Photochemical and Photobiological Sciences. 9, 4, p. 571-577

Research output: Contribution to journalArticle

19 Citations (Scopus)

UV inhibits allergic airways disease in mice by reducing effector CD4 + T cells

Mcglade, J. P., Strickland, D., Lambert, M. J., Gorman, S., Thomas, J. A., Judge, M. A., Burchell, J., Zosky, G. & Hart, P., 2010, In : Clinical and Experimental Allergy. 40, 5, p. 772-785

Research output: Contribution to journalArticle

2007
27 Citations (Scopus)

CD4+ T cells in lymph nodes of UVB-irradiated mice suppress immune responses to new antigens both in vitro and in vivo

Gorman, S., Tan, J. W., Yerkovich, S. T., Finlay-Jones, J. & Hart, P., 2007, In : Journal of Investigative Dermatology. 127, 4, p. 915-924

Research output: Contribution to journalArticle

T-cells
Skin
Lymph Nodes
T-Lymphocytes
Antigens
30 Citations (Scopus)

Effect of both ultraviolet B irradiation and histamine receptor function on allergic responses to an inhaled antigen

Mcglade, J. P., Gorman, S., Lenzo, J. C., Tan, J. W., Watanabe, T., Finlay-Jones, J., Thomas, W. & Hart, P., 2007, In : Journal of Immunology. 178, 5, p. 2794-2802

Research output: Contribution to journalArticle

Histamine Receptors
Papain
Antigens
Lymph Nodes
Lung
189 Citations (Scopus)

Topically applied 1,25-dihydroxyvitamin D3 enhances the suppressive activity of CD4+CD25+ cells in the draining lymph nodes

Gorman, S., Kuritzky, L. A., Judge, M. A., Dixon, K. M., Mcglade, J. P., Mason, R. S., Finlay-Jones, J. & Hart, P., 2007, In : Journal of Immunology. 179, 9, p. 6273-6283

Research output: Contribution to journalArticle

Calcitriol
Lymph Nodes
Skin
Vitamin D
Adoptive Transfer
2006
31 Citations (Scopus)

Mixed infection with multiple strains of murine cytomegalovirus occurs following simultaneous or sequential infection of immunocompetent mice

Gorman, S., Harvey, N. L., Moro, D., Lloyd, M., Voigt, V., Smith, L., Lawson, M. & Shellam, G., 2006, In : Journal of General Virology. 87, 5, p. 1123-1132

Research output: Contribution to journalArticle

Muromegalovirus
Coinfection
Infection
Lac Operon
Salivary Glands
2005
26 Citations (Scopus)

Primary defect in UVB-induced systemic immunomodulation does not relate to immature or funtionally impaired APCs in regional lymph nodes

Gorman, S., Tan, J. W. Y., Thomas, J. A., Townley, S. L., Stumbles, P., Finlay-Jones, J. & Hart, P., 2005, In : Journal of Immunology. 174, 11, p. 6677-85

Research output: Contribution to journalArticle

Immunomodulation
Lymph Nodes
Fluorescein-5-isothiocyanate
Haptens
Contact Dermatitis
17 Citations (Scopus)

Transmission of two Australian strains of murine cytomegalovirus (MCMV) in enclosure populations of house mice (Mus domesticus)

Farroway, L. N., Gorman, S., Lawson, M., Harvey, N. L., Jones, D. A., Shellam, G. & Singleton, G. R., 2005, In : Epidemiology and Infection. 133, 4, p. 701-710

Research output: Contribution to journalArticle

Muromegalovirus
Population
DNA Viruses
Plague
Victoria