Sebastien Malinge

Adjunct Senior Research Fellow, UWA Centre for Child Health Research

Emailsebastien.malinge@uwa.edu.au

The University of Western Australia (M560), 35 Stirling Highway,
6009 Perth
Australia

Source: Scopus
Calculated using citation counts from Scopus for publications in the UWA Profiles and Research Repository

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49 Citations
4 h-Index
7 Article
1 Comment/debate
1 Letter
1 Review article

DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3
Bhansali, R. S., Rammohan, M., Lee, P., Laurent, A. P., Wen, Q., Suraneni, P., Yip, B. H., Tsai, Y. C., Jenni, S., Bornhauser, B., Siret, A., Fruit, C., Pacheco-Benichou, A., Harris, E., Besson, T., Thompson, B. J., Goo, Y. A., Hijiya, N., Vilenchik, M., Izraeli, S. & 3 others, Bourquin, J. P., Malinge, S. & Crispino, J. D., 4 Jan 2021, In : Journal of Clinical Investigation. 131, 1, e135937.
Research output: Contribution to journal › Article

Open Access
2 Citations (Scopus)
Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia
Cheung, L. C., de Kraa, R., Oommen, J., Chua, G. A., Singh, S., Hughes, A. M., Ferrari, E., Ford, J., Chiu, S. K., Stam, R. W., Kees, U. R., Malinge, S. & Kotecha, R. S., 15 Apr 2021, In : Frontiers in Oncology. 11, 631594.
Research output: Contribution to journal › Article

Open Access
Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia
Laurent, A. P., Siret, A., Ignacimouttou, C., Panchal, K., Diop, MB., Jenni, S., Tsai, Y. C., Roos-Weil, D., Aid, Z., Prade, N., Lagarde, S., Plassard, D., Pierron, G., Daudigeos, E., Lecluse, Y., Droin, N., Bornhauser, B. C., Cheung, L. C., Crispino, J. D., Gaudry, M. & 10 others, Bernard, O. A., Macintyre, E., Barin Bonnigal, C., Kotecha, R. S., Geoerger, B., Ballerini, P., Bourquin, J. P., Delabesse, E., Mercher, T. & Malinge, S., Jul 2020, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 13, p. 3307-3318 12 p.
Research output: Contribution to journal › Article

Open Access
4 Citations (Scopus)
Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome
Laurent, A. P., Kotecha, R. S. & Malinge, S., 1 Aug 2020, In : Leukemia. 34, 8, p. 1984-1999 16 p.
Research output: Contribution to journal › Review article

Open Access
4 Citations (Scopus)
Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers
Fagnan, A., Bagger, F. O., Piqué-Borràs, M. R., Ignacimouttou, C., Caulier, A., Lopez, C. K., Robert, E., Uzan, B., Gelsi-Boyer, V., Aid, Z., Thirant, C., Moll, U., Tauchmann, S., Kurtovic-Kozaric, A., Maciejewski, J., Dierks, C., Spinelli, O., Salmoiraghi, S., Pabst, T., Shimoda, K. & 24 others, Deleuze, V., Lapillonne, H., Sweeney, C., De Mas, V., Leite, B., Kadri, Z., Malinge, S., de Botton, S., Micol, J. B., Kile, B., Carmichael, C. L., Iacobucci, I., Mullighan, C. G., Carroll, M., Valent, P., Bernard, O. A., Delabesse, E., Vyas, P., Birnbaum, D., Anguita, E., Garçon, L., Soler, E., Schwaller, J. & Mercher, T., 6 Aug 2020, In : Blood. 136, 6, p. 698-714 17 p.
Research output: Contribution to journal › Article
12 Citations (Scopus)

1 Finished
1 Active

Targeting the treatment-resistant cells to prevent relapse in childhood leukaemia
Malinge, S.
Cancer Council NSW
1/01/20 → 31/12/23
Project: Research
Targeting DYRK1A: A Key Player in Down Syndrome Leukaemogenesis
Malinge, S.
Jerome Lejeune Foundation
1/01/19 → 12/06/21
Project: Research

DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3

Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia

Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia

Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Targeting the treatment-resistant cells to prevent relapse in childhood leukaemia

Targeting DYRK1A: A Key Player in Down Syndrome Leukaemogenesis