• The University of Western Australia (M706), 35 Stirling Highway,

    6009 Perth

    Australia

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Personal profile

Biography

Dr Sebastian Amos is a Lecturer and Anatomy Discipline Lead at the Medical School who completed his PhD in Cancer Mechanobiology and Bioimage Informatics.

Teaching overview

Sebastian has been teaching anatomy at UWA since 2017 and has taught in a wide range of undergraduate and postgraduate units. He leverages his interests in programming and image science to create and deploy 3D digital and printed resources for anatomical teaching.

Roles and responsibilities

Discipline Lead, Anatomy, UWA Medical School

Research

Sebastian's PhD centred around the role of cellular adhesion in tumour growth and cancer metastasis. He was part of an international collaboration that characterised the Adherent-to-Suspension Transition, a novel paradigm in cancer cell dissemination. 

Working extensively with 3D cell culture and various imaging modalities, Sebastian also developed his own 3D image analysis software, The Fluorescent Object and Cell gpU-accelerated Segmentation Toolbox (FOCUST), which is freely available as a plugin for the FIJI distribution of ImageJ. Sebastian also worked closely with other collaborators on projects focusing on stem cell, cardiac, neuronal/glial and airway mechanobiology, drug delivery, preterm birth, tumour-immune biology and novel optical and mechanical imaging techniques.

Sebastian has broad interests in quantitative biomedical image and data science, with experience in acquiring and analysing diverse and complex datasets.

Current research interests:

  • Bioimage analysis and informatics for 2D and 3D cell biology
  • Quantitative image analysis for histopathology
  • Segmentation and quantification of medical imaging datasets

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 17 - Partnerships for the Goals

Research expertise keywords

  • 3D Image Analysis
  • Bioimage Informatics
  • Optical Microscopy
  • Mechanobiology
  • Biomedical Data Science
  • Segmentation & Quantification

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Collaborations and top research areas from the last five years

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