Sebastian Amos

Sebastian Amos

Mr, Doctor of Philosophy Student

  • The University of Western Australia (M309), 35 Stirling Highway,

    6009 Perth

    Australia

  • Source: Scopus
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Personal profile

Biography

Sebastian is a PhD candidate working in the Choi Mechanobiology Lab in the School of Human Sciences. Sebastian’s research focuses on the changes to cell adhesion and behaviour that allow cancer cells to negotiate the mechanical challenges of the metastatic cascade. Metastasis, whereby cells from a primary tumour spread to other tissues, is the primary cause of cancer-related death. Yet, how cancer cells survive the mechanical challenges of this journey remains incompletely understood. Sebastian utilises and designs various platforms to study each step of the metastatic cascade, drawing on collaborative expertise in 3D biomaterials, soft lithography, microfluidics and 3D image analysis. Adopting a transdisciplinary approach, Sebastian is collaborating with biomedical engineering (BRITElab, Harry Perkins Institute of Medical Research), bioengineering (Confinement Mechanobiology Lab, Mechanbiological Institute, National University of Singapore) and molecular and biochemistry (Park Lab, Yonsei University) groups to study the mechanobiology of metastatic cancers. Sebastian is supported by a Hackett Postgraduate Research Scholarship, The University Club of WA Research Travel Scholarship and the BioZone PhD Program.

Sebastian also works closely with other collaborators on projects focusing on stem cell and cardiac mechanobiology, drug delivery, and tumour-immune interactions.
In addition to his research, Sebastian works as a Prosector and keen educator of anatomy within the School of Human Sciences. 

Teaching overview

Sebastian has been teaching anatomy in the School of Human Sciences since 2017. In various capacities, Sebastian facilitates undergraduate and postgraduate student learning of developmental, structural and functional concepts of anatomy using cadaveric material in laboratory sessions and guest lectures.

  • ANHB2212: Human Structure and Development (Demonstrator and Tutor: 2017 – Current)
  • ANHB3324: Human Structure and Function (Guest lecturer 2018, Demonstrator 2018  – Current )
  • IMED1001: Form and Function (Demonstrator 2018 – 2021)
  • IMED4443: Integrated Medical Sciences I (Demonstrator: 2018 – 2020)
  • IMED3111: Integrated Medical Systems I (Demonstrator: 2022)
  • IMED3112: Integrated Medical Systems II (Demonstrator: 2022)
  • IMED3001: Body Systems and Disease I (Demonstrator: 2018 – 2021, Guest Lecturer 2019 – 2021)
  • IMED3003: Body Systems and Disease III (Demonstrator: 2018 – 2020)
  • IMED3004: Body Systems and Disease IV (Demonstrator: 2018 – 2020)
  • IMED4220: Integrated Medical Practice I (Part time demonstrator: 2022)

Previous positions

  • Graduate Research Assistant for Professor Jane Pillow at the Preclinical Intensive Care Research Unit, UWA (Jan 2019 - Dec 2019)

Education/Academic qualification

Anatomy & Human Biology and Physiology, Bachelor of Science, The University of Western Australia

Physiology, Bachelor of Science (Honours) , The University of Western Australia

Research expertise keywords

  • Mechanobiology
  • Hydrogels
  • Image analysis
  • Metastasis

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