Scott Stewart

Dr, BSc Deakin, PhD ANU

  • The University of Western Australia (M313), 35 Stirling Highway, Room 330, Bayliss Building, Perth campus

    6009 Crawley

    Australia

  • 1145 Citations
  • 19 h-Index
19982018
If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

A/Prof Scott Stewart completed a PhD at the Research School of Chemistry (ANU) and in 2002, A/Prof Stewart was awarded an Alexander von-Humboldt Fellowship to work at the Universität Göttingen, Germany. He was appointed at The University of Western Australia in late 2005. In 2010 A/Prof Stewart was awarded the RACI Athel Beckwith Lectureship and a second Alexander von-Humboldt Fellowship. Recently he has received Fellowship from the Japan Society for the Promotion of Science and the Tasmanian Alkaloids Lectureship.

Funding overview

Cancer Council of Western Australia
Alexander von-Humboldt Stiftung/Foundation
Ada Bartholomew Medical Research Trust Grant
School of Medicine, Dentistry and Health
UWA Priming Grant
Australian Institute of Nuclear Science and Engineering
NH&MRC

Current projects

Nickel Catalysis in modern organic synthesis

The synthesis of indole alkaloid natural products

Rhodium catalysis methedology

Pyrrolesesquiterpene natural product synthesis

Synthesis of Thalidomide Derivatives for treatment of liver cancer

Natural Product Synthesis Utilising Palladium Catalysis

The preperation of anthrapyranone natural products as highly active antimicrobial and anticancer agents

The mechanism of enzymatic oxidative coupling reactions in biosynthesis


Collaborators

Dr. Kersten Gericke, Bayer AG

Dr Donald Bierer, Bayer AG.

Professor Masahiro Murakami, University of Kyoto

A/Professor Tomoya Miura, University of Kyoto

Professor George Yeoh, Biochemistry and Molecular Biology, UWA

Professor Lutz F Tietze, Universität Göttingen

Dr Yiy Heng Chooi, UWA

A Professor Frederick Pfeffer, School of Biological and Chemical Sciences, Deakin University

 

Teaching overview

CHEM3004 Modern Organic Synthesis (Course Coordinator)

CHEM1002 Organic Chemistry (Course Coordinator)

Research

Research interests include:

1. The efficient synthesis of natural products and their simplified ring systems.

2. The development of palladium and nickel catalysed cross coupling reactions

3. The use of domino type reactions in organic synthesis

4. The synthesis of new nickel catalysts

5. Medicinal chemistry: antibacterial agents; thalidomide analogues; anti-cancer agents

Keywords

  • Synthetic organic chemistry
  • Reaction methodology
  • Natural products and natural product synthesis
  • Nickel catalysis
  • Palladium and nickel mediated cross coupling reactions
  • Domino transformations
  • Medicinal chemistry
  • Anti-bacterial agents
  • Thalidomide

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Nickel Chemical Compounds
Biological Products Chemical Compounds
Phosphites Chemical Compounds
Catalysts Chemical Compounds
phosphine Chemical Compounds
Palladium Chemical Compounds
Derivatives Chemical Compounds
Thalidomide Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2013

Research Output 1998 2018

  • 1145 Citations
  • 19 h-Index
  • 57 Article
  • 2 Chapter
  • 1 Doctoral Thesis
2 Citations

Nickel Phosphite/Phosphine-Catalyzed C-S Cross-Coupling of Aryl Chlorides and Thiols

Jones, K. D., Power, D. J., Bierer, D., Gericke, K. M. & Stewart, S. G., 5 Jan 2018, In : Organic Letters. 20, 1, p. 208-211 4 p.

Research output: Contribution to journalArticle

phosphine
Phosphites
cross coupling
Nickel
Sulfhydryl Compounds
1 Citations

Spectrum of antibacterial activity and mode of action of a novel tris-stilbene bacteriostatic compound

Man, N. Y. T., Knight, D. R., Stewart, S. G., McKinley, A. J., Riley, T. V. & Hammer, K. A., 2 May 2018, In : Scientific Reports. 8, 9 p., 6912

Research output: Contribution to journalArticle

Open Access

Synthesis of 1,3,4-Oxadiazoles via Annulation of Hydrazides and Benzene-1,3,5-triyl Triformate under Metal-Free Conditions

Yin, Z., Power, D. J., Wang, Z., Stewart, S. G. & Wu, X. F., 16 Apr 2018, In : Synthesis (Germany). 50, 16, p. 3238-3242

Research output: Contribution to journalArticle

Benzene
Functional groups
Metals
1,3,4-oxadiazole
File
Anti-Infective Agents
Nickel
Catalysts
Teichoic Acids
Palladium
1 Citations

Approaching an experimental electron density model of the biologically active trans-epoxysuccinyl amide group—Substituent effects vs. crystal packing

Shi, M. W., Stewart, S. G., Sobolev, A. N., Dittrich, B., Schirmeister, T., Luger, P., Hesse, M., Chen, Y. S., Spackman, P. R., Spackman, M. A. & Grabowsky, S., 1 Nov 2017, In : Journal of Physical Organic Chemistry. 30, 11, p. 1-15 15 p., e3683

Research output: Contribution to journalArticle

Open Access
File
Amides
amides
Carrier concentration
Crystals
activity (biology)