Scott Fisher

Dr, BSc Curtin, PhD W.Aust.

  • The University of Western Australia (M503), 35 Stirling Highway,

    6009 Perth

    Australia

  • 200 Citations
  • 9 h-Index
19992022
If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

I am a research scientist with a background in molecular biology / virology and have over 19 years' experience in using small animal models for studies in infectious diseases and cancer research. For the last 11 years I have focused on cancer immunology and immunotherapy. My main area of research is centred on the use of pre‑clinical mouse models of mesothelioma (transplantable and transgenic), to better understand; a) how host genetics affect mesothelioma development after asbestos exposure; b) assess the carcinogenic potential of different asbestos and asbestiform fibres; c) assess the impact of voluntary exercise as an adjunctive strategy to improve the efficacy and tolerability of anti-cancer treatment for mesothelioma and d) understanding the host-cancer immune response to better develop and use novel immunotherapies with the aim of improving current treatment options for mesothelioma and other solid malignancies.

Roles and responsibilities

Research scientist

Previous positions

Nov 2004-May 2006: PostDoc University of Michigan (Ann Arbor, USA). School of Microbiology and Immunology.

May 2006-May 2008: PostDoc. Laboratory of Vaccine Research. Beckman Research Institute/City of Hope National Medical Centre. Duarte CA USA.

June 2008-present: Research Scientist. Tumour Immunology Group. UWA School Medicine and Pharmacology (SCGH Unit). Perth, Western Australia.

Current projects

Projects are centred around

1) How host genetics affect mesothelioma development after asbestos exposure

2) Assessing the carcinogenic potential of different asbestos and asbestiform fibres

3) Understanding the impact of voluntary exercise as an adjunctive strategy to improve the efficacy and tolerability of anti-cancer treatment for mesothelioma

4) Understanding the host-cancer immune response to better develop and use novel immunotherapies with the aim of improving treatment options for mesothelioma and other solid malignancies

Projects are suited to both Honours and PhD students. Enquiries welcome.

Research

Tumour Immunology/Immunotherapy
Molecular biology
Mesothelioma

Keywords

  • Abestos
  • Mesothelioma
  • Mesothelioma, genetics of
  • Immunology—T cell
  • Immunotherapy
  • Cancer immunology
  • Tumour immunology
  • Tumour immunotherapy
  • Viral vectors
  • Molecular and cellular biology

Fingerprint Dive into the research topics where Scott Fisher is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 32 Similar Profiles
Mesothelioma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Hepacivirus Medicine & Life Sciences
Cancer Vaccines Medicine & Life Sciences
Vaccination Medicine & Life Sciences
Asbestos Medicine & Life Sciences
Antigens Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1999 2019

  • 200 Citations
  • 9 h-Index
  • 13 Article
  • 3 Review article
  • 1 Chapter
  • 1 Doctoral Thesis

The Future of Mesothelioma Research: Basic Science Research

Fear, V., Cook, A. & Fisher, S., 2019, Caring for Patients with Mesothelioma: Principles and Guidelines. Switzerland: Springer Nature, p. 203-227 24 p.

Research output: Chapter in Book/Conference paperChapter

Mesothelioma
Research
Therapeutics
Drug Repositioning
Radiotherapy

Bibliometric analysis of gaps in research on asbestos-related diseases: Declining emphasis on public health over 26 years

Lin, R. T., Soeberg, M. J., Chien, L. C., Fisher, S., Takala, J., Lemen, R., Driscoll, T. & Takahashi, K., 1 Jul 2018, In : BMJ Open. 8, 7, e022806.

Research output: Contribution to journalArticle

Open Access
Bibliometrics
Asbestos
Public Health
Research
Primary Prevention
1 Citation (Scopus)

Combination immune checkpoint blockade as an effective therapy for mesothelioma

Fear, V., Tilsed, C. M., Chee, H. E. J., Forbes, C., Casey, T., Solin, J., Lansley, S., Lesterhuis, W., Dick, I., Nowak, A., Robinson, B., Lake, R. & Fisher, S., 30 Jul 2018, In : Oncolmmunology. 14 p., e1494111.

Research output: Contribution to journalArticle

Open Access
Mesothelioma
Neoplasms
Therapeutics
Asbestos
Regulatory T-Lymphocytes
9 Citations (Scopus)
115 Downloads (Pure)

Transient Treg depletion enhances therapeutic anti-cancer vaccination

Fisher, S., Aston, W., Chee, H. E. J., Khong, A., Cleaver, A., Solin, J., Ma, S., Lesterhuis, W., Dick, I., Holt, R., Creaney, J., Boon, L., Robinson, B. & Lake, R., Mar 2017, In : Immunity Inflammation and Disease.. 5, 1, p. 16-28 12 p., 10.1002/iid3.136.

Research output: Contribution to journalArticle

Open Access
File
Vaccination
Neoplasms
Diphtheria Toxin
Therapeutics
Immunity
9 Citations (Scopus)
154 Downloads (Pure)

Immunotherapy for lung cancer

Steven, A., Fisher, S. A. & Robinson, B. W., 21 Apr 2016, In : Respirology. 21, 5, p. 821-833 12 p., doi: 10.1111/resp.12789.

Research output: Contribution to journalReview article

Open Access
File
Immunotherapy
Lung Neoplasms
Cancer Vaccines
Neoplasms
Therapeutics

Projects 2009 2022