Personal profile
Biography
Samantha is a PhD student in the Cancer Immunotherapy Team under the supervision of Dr Bree Foley, Dr Emma de Jong, Dr Sonia Fernandez, Dr Alison McDonnell, and Dr Jason Waithman.
Prior to her PhD, Samantha first joined the team as a research assistant in 2019 before completing her Master of Pathology project in 2020. With a research focus in NK cell biology and adoptive cell therapy, her PhD project aims to use a suite of sophisticated bioinformatics platforms to understand the molecular drivers of enhanced NK cell function. The ultimate goal of this work is to identify novel targets that can be leveraged to boost the efficacy of NK cell therapies against leukaemia.
Engagement
Committee member for the WA branch of the Australian and New Zealand Society for Immunology (ASI) (2021 - ongoing)
Education/Academic qualification
Master of Pathology, The University of Western Australia
2020
Master of Clinical Pathology, The University of Western Australia
2017 → 2018
Genetics, Microbiology and Immunology, Bachelor of Science, The University of Western Australia
2014 → 2016
Research expertise keywords
- NK cells
- Leukaemia
- Flow cytometry
- Adoptive cell therapy
- Immunotherapy
- RNA sequencing
- Cancer immunology
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Collaborations and top research areas from the last five years
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Interleukin-4 modulates type I interferon to augment antitumor immunity
Newnes, H. V., Armitage, J. D., Buzzai, A. C., de Jong, E., Audsley, K. M., Barnes, S. A., Srinivasan, S., Serralha, M., Fear, V. S., Guo, B. B., Jones, M. E., Forrest, A. R. R., Foley, B., Darcy, P. K., Beavis, P. A., Bosco, A. & Waithman, J., 16 May 2025, In: Science Advances. 11, 20, 14 p., eadt3618.Research output: Contribution to journal › Article › peer-review
3 Link opens in a new tab Citations (Scopus) -
Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells
Barrett, L. W., Fear, V. S., Foley, B., Audsley, K., Barnes, S., Newnes, H., McDonnell, A., Wood, F. M., Fear, M. W. & Waithman, J., 2022, In: Burns and Trauma. 10, tkac016.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Citations (Web of Science) -
Type I interferon subtypes differentially activate the anti-leukaemic function of natural killer cells
Barnes, S. A., Audsley, K. M., Newnes, H. V., Fernandez, S., de Jong, E., Waithman, J. & Foley, B., 24 Nov 2022, In: Frontiers in Immunology. 13, 1050718.Research output: Contribution to journal › Article › peer-review
Open Access14 Link opens in a new tab Citations (Scopus) -
IFNβ Is a Potent Adjuvant for Cancer Vaccination Strategies
Audsley, K. M., Wagner, T., Ta, C., Newnes, H. V., Buzzai, A. C., Barnes, S. A., Wylie, B., Armitage, J., Kaisho, T., Bosco, A., McDonnell, A., Cruickshank, M., Fear, V. S., Foley, B. & Waithman, J., 6 Sept 2021, In: Frontiers in Immunology. 12, 735133.Research output: Contribution to journal › Article › peer-review
Open Access21 Link opens in a new tab Citations (Scopus) -
Making a Killer: Selecting the Optimal Natural Killer Cells for Improved Immunotherapies
Barnes, S. A., Trew, I., de Jong, E. & Foley, B., 27 Oct 2021, In: Frontiers in Immunology. 12, 765705.Research output: Contribution to journal › Review article › peer-review
Open Access16 Link opens in a new tab Citations (Scopus)