Research output per year
Research output per year
Dr, BSc Murd., PhD W.Aust.
The University of Western Australia (M561), 35 Stirling Highway,
6009 Perth
Australia
Dr Ruth Thornton is a Passe and Williams Foundation Mid-Career Research Fellow within The Centre for Child Health Research at the University of Western Australia and Co-Lead of the Bacterial Respiratory Infectious Disease Group at the Telethon Kids Institute. Her research interests lie in understanding the interactions between bacteria and the host in chronic and recurrent respiratory infections including ear, nose and throat infections, and chronic lung disease.
Dr Thornton’s research into the role of bacterial biofilms, intracellular persistence and host immunity in recurrent middle ear infections (otitis media) has changed paradigms in understanding and treating otitis media. She demonstrated that otopathogenic bacteria exist in biofilms and intracellularly in the middle ear mucosa of children with chronic and recurrent otitis media. She also demonstrated that the middle ear fluid contains host DNA which can be used by the bacteria as scaffolding to persist in the middle ear. This DNA scaffolding can be targeted to prevent recurrent ear infections and repeat surgeries following grommet surgery. This is the basis of the ATOMIC ears clinical trial which she currently leads at Perth Children’s Hospital, investigating the safety and effectiveness of using an anti-biofilm agent to treat recurrent and chronic otitis media.
Passe and Williams Foundation Mid-Career Research Fellow
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
McLeod, C., Richmond, P., Snelling, T., Flanagan, K., Plebanski, M., Marsh, J., Dymock, M., Williams, P., Thornton, R., Nicholson, S., Faust, S. & Blyth, C.
Medical Research Future Fund MRFF
29/06/23 → 30/05/25
Project: Research
Thornton, R., Richmond, P., Kirkham, L., Vijayasekaran, S., Brennan-Jones, C., Li, I., Kuthubutheen, J., Herbert, H. & Friedland, P.
Department of Health (Western Australia)
1/01/23 → 1/12/25
Project: Research
Blyth, C., Smith, D., Kirkham, L., Thornton, R., Bhuiyan, M. & Jacoby, P.
1/01/16 → 31/12/17
Project: Research
Kirkham, L., Thornton, R., Richmond, P., Pickering, J., Blyth, C., Bowen, A., Van Den Biggelaar, A., Prescott, S., Gamez Gamez, C., Strunk, T., Adams, L., Stick, S., Kicic, A., Le Souef, P., Laing, I., Hales, B. & Baltic, S.
National Health & Medical Research Council NHMRC
1/01/16 → 31/12/17
Project: Research
Barry, Kristin (Recipient), Valente, Filippo (Recipient), Thornton, Ruth (Recipient), Ong, Huan Ting (Recipient), Forrest, Alistair (Recipient), Mulders, Wilhelmina (Recipient), Atlas, Marcus (Recipient) & Clark, Sharon (Recipient), 2022
Prize
Valente, Filippo (Recipient), Thornton, Ruth (Recipient), Mulders, Wilhelmina (Recipient), Barry, Kristin (Recipient), Al-Salami, Hani (Recipient), Kicic, Anthony (Recipient), Ong, Ting (Recipient), Atlas, Marcus (Recipient) & Allardyce, Benjamin J. (Recipient), Dec 2021
Prize: Other distinction